导师姓名： 郑家伟 专业代码： 100302
性别： 男 专业名称： 口腔临床医学
培养单位： 附属第九人民医院 三级学科/
专业领域：
导师类型： 博士生导师 专业学位导师： 兼
联系方式：
邮编： 200011 邮箱地址： davidzhengjw@sjtu.edu.cn

研究方向 (点击浏览详细信息)
口腔颌面部血管瘤与脉管畸形的基础与临床研究

社会任职
《Frontiers of Oral and Maxillofacial Medicine，FOMM》（英文杂志）主编
中华口腔医学会口腔颌面外科专业委员会脉管性疾病学组副组长
Chinese Medical Journal(SCI收录) 编委
Journal of Oral and Maxillofacial Surgery(SCI收录) 国际编委
中华口腔医学会口腔医学教育专业委员会副主任委员
全国统编教材《口腔颌面外科学》编委
《口腔颌面外科学精要》主编
《上海口腔医学》常务副主编
第六届中华口腔医学会口腔颌面外科专业委员会常委
《中国口腔颌面外科杂志》主编
《中华医学教育探索杂志》编委
《Advances in oral and maxillofacial surgery》（专著）主编
Asian Journal of Oral and Maxillofacial Surgery编委
《口腔医学解剖图谱》主译
国际口腔颌面外科医师协会会员
国际脉管异常研究学会（ISSVA） 委员
Head and Neck Oncology (SCI收录)编委

科研项目 项目编号项目名称课题来源起止年月批准经费承担职责
** 血管瘤干细胞通过外泌体途径调控血管瘤发生、发展的机制研究 国家自然科学基金 2018-01~2021-12 56万元 课题负责人
** 普萘洛尔等纳米制剂治疗血管瘤的作用及机制研究 国家自然科学基金 2015-01~2018-12 73万元 课题负责人
** 血管瘤干细胞联合雌激素构建血管瘤动物模型及其机制的研究 国家自然科学基金 2013-01~2016-12 70万元 课题负责人
** 血管瘤组织中肿瘤干细胞的成瘤作用及干预试验 国家自然科学基金 2011-01~2011-12 10万元 课题负责人
** RASA1突变与Sturge-Weber综合征的关系研究 国家自然科学基金 2007-01~2009-12 28万元 课题负责人
**/C** 转基因小鼠组织特异性表达血管瘤模型的建立 国家自然科学基金 2004-01~2006-12 20万元 课题负责人

学术论文 作者论文标题期刊名出版年卷期页码
Wu H, Wang X, Liang H, Zheng J （通讯作者）, Huang S, Zhang D Enhanced efficacy of propranolol therapy for infantile hemangiomas based on a mesoporous silica nanoplatform through mediating autophagy dysfunction Acta Biomater 2020 107:272-285
Wu H, Wang X, Zheng J （通讯作者）, Zhang L, Li X, Yuan WE, Liu X Propranolol-loaded mesoporous silica nanoparticles for treatment of infantile hemangiomas Adv Healthc Mater 2019 6:e**
Zhao Z, Liu C, Wu H, Zhao H, Zheng J （通讯作者） Sclerotherapy with polidocanol foam is a promising perspective treatment for pyogenic granuloma: a retrospective analysis in 52 cases Clin Surg 2019 4:2680
Liu C, Zhao Z, Wu H （通讯作者）, Zheng J, Wang Y, Liu X, Fan X Effect of combined low-dose oral prednisone with beta-adrenergic receptor antagonists for refractory infantile hemangiomas: retrospective cohort study in 76 patients Ann Transl Med 2019 2019,7(23):750
Liu C, Zhao Z, Ji Z, Jiang Y, Zheng J （通讯作者） MiR-187-3p enhances propranolol sensitivity of hemangioma stem cells Cell Struct Funct 2019 44(1):41-50
Fu JY, Zhang CP, Gao J, Luo JF, Li J, Zheng JW （通讯作者） Estimate of health burden on smoking-associated oral cancer in Shanghai and its surrounding areas Chin J Det Res 2018 2018,21(2):127-134
Wu HW, Wang X, Zhang L, Zheng JW （通讯作者）, Liu C, Wang YA Topical timolol vs. oral propranolol for the treatment of superficial infantile hemangiomas Front Oncol 2018 8:605
Liu X, Shen P, Wang X, Zhang S, Zheng J （通讯作者）,Yang C A prognostic nomogram for postoperative bone remodeling in patients with ADDWoR Sci Rep 2018 2018,8:4361
Zhang L, Wu HW, Yuan WE, Zheng JW （通讯作者） Estrogen-mediated hemangioma derived stem cells through estrogen receptor-αfor infantile hemangioma Cancer Manag Res 2017 9:279-286
Wu HW, Liu C, Wang X, Zhang L, Yuan W, Zheng JW （通讯作者）, Su LX, Fan XD Topical application of 0.5% timolol maleate hydrogel for the treatment of superficial infantile hemangioma Front Oncol 2017 2017,7:137
Zhang L,Wu H, Yuan W, Zheng J （通讯作者） Propranolol therapy for infantile hemangioma- our experience Drug Des Dev Ther 2017 11:1401-1408
Ge J, Yang C, Zheng J （通讯作者）, Hu Y Autogenous bone grafting for treatment of osseous defect after impacted mandibular third molar extraction: A randomized controlled trial Clin Implant Dent Relat Res 2017 19(3):572-580
Ge J, Zheng JW （通讯作者）, Yang C, Qian WT Variations in the buccal-lingual alveolar bone thickness of impacted mandibular third molar: our classification and treatment perspectives Sci Rep 2016 6:16375
Zhu L, Zhang C, Yang J, Yu Q, Zheng JW （通讯作者） Diffusion weighted-MRI in distinguishing between tumor-like benign lympho-epithelial lesion and mucosa-associated lymphoid tissue lymphoma of parotid gland Int J Clin Exp Med 2016 9(3):6295-6301
Zhu L, Zhang C, Hua Y, Yang J, Yu Q, Tao X, Zheng J （通讯作者） Dynamic contrast-enhanced MR in the diagnosis of lympho-associated benign and malignant lesions in the parotid gland Dentomaxillofac Radiol 2016 45(4):**
Zhang L, Yuan WE, Zheng JW （通讯作者） Pharmacological therapies for infantile hemangiomas: A clinical study in 853 consecutive patients using a standard treatment algorith Sci Rep 2016 6:21670
Liu X, Li J,Qu X, Yan W, Zhang L, Yang C, Zheng J （通讯作者） Treatment of kaposiform hemangioendothelioma and tufted angioma Int J Cancer 2016 139(7):1658–1666
Liu X, Li J, Qu X, Yan W, Zhang L, Zhang S, Yang C, Zheng J （通讯作者） Clinical outcome for systemic corticosteroids versus vincristine in treating kaposiform hemangioendothelioma and tufted angioma Medicine 2016 95(20):e3431
Ge J, Yang C, Zheng J （通讯作者）, Qian W Piezosurgery for the lingual split technique in lingual positioned impacted mandibular third molar removal: a retrospective study Medicine 2016 95(12):e3192
Ge J, Zheng J （通讯作者）, Zhang L,Yuan W, Zhao H Oral propranolol combined with topical timolol for compound infantile hemangiomas: a retrospective study Sci Rep 2016 6:19765
Chen ZG陈正岗, Zheng JW （通讯作者）, Yuan ML, Zhang L, Yuan WE A novel topical nano-propranolol for treatment of infantile hemangiomas Nanomedicine 2015 （11):1109–1115
Liu X, Qu X, Zheng J （通讯作者）, Zhang L Effectiveness and safety of oral propranolol versus other treatments for infantile hemangiomas: a meta-analysis PLoS One 2015 10(9):e**
Zhang L,张凌Zheng JW （通讯作者）, Yuan WE Treatment of alarming head and neck infantile hemangiomas with interferon-α2a: a clinical study in eleven consecutive patients Drug Des Dev Ther 2015 9:723-727
Zhu L朱凌, Yang J, Zheng J （通讯作者） Radiological and clinical features of peripheral keratocystic odontogenic tumor Int J Clin Exp Med 2014 7(1): 300-306
Zhang L张凌, Mai H, Zheng J （通讯作者）, Zheng J, Wang Y, Qin Z, Li K Propranolol inhibits angiogenesis via down-regulating the expression of vascular endothelial growth factor in hemangioma derived stem cell Int J Clin Exp Pathol 2014 7(1): 48-55
Zhang L,张凌Mai H, Zheng J （通讯作者）, Zheng J, Wang Y, Qin Z, Li K Propranolol inhibits angiogenesis via down-regulating the expression of vascular endothelial growth factor in hemangioma derived stem cell Int J Clin Exp Pathol 2014 7(1): 48-55
Yan G, Zou R, Chen Z, Fan B, Wang Z, Wang Y, Yin X, Zhang D, Tong L, Yang F, Jiang W, Fu W, Zheng J （通讯作者）, Bergo MO, Dalin M, Zheng J, Chen S, Zhou J Silencing RhoA inhibits migration and invasion through Wnt/β-catenin pathway and growth through cell cycle regulation in human tongue cancer Acta Biochim Biophys Sin (Shanghai) 2014 46(8):682-690
Fu J, Gao J, Zhang Z, Zheng J （通讯作者）, Zhong L, Luo J, Xiang Y Role of cigarette filter on the risk of oral cancer: a case-control study in a Chinese population Oral Dis 2013 19(1):80-84
Mai HM麦华明, Zheng JW （通讯作者）, Wang YA, Yang XJ, Zhou Q, Qin ZP, Li KL CD133 selected stem cells from proliferating infantile hemangioma and establishment of an in vivo mice model of hemangioma Chin Med J (Engl) 2013 126(1):88-94
Fu JY, Gao J, Zhang ZY, Zheng JW （通讯作者）, Zhong LP, Luo JF, Xiang YB Role of cigarette filter on the risk of oral cancer: a case-control study in a Chinese population Oral Dis 2013 19(1):80-84
Mai HM麦华明, Zheng JW （通讯作者）, Zhou Q, Yang XJ, Wang YA, Fan XD Intralesional injection of pingyangmycin is a safe and effective treatment for microcystic lymphatic malformations in the tongue Phlebology 2013 28(3):147-152
Zhang L张凌, Mai HM, Zheng J （通讯作者）, Zheng JW, Chen ZG, Wang YA, Qin ZP, Li KL, Yuan W Preliminary study on plasma PRN concentration of patients with infantile hemangioma treated with propranolol Int J Clin Exp Med 2013 6(5):342-345
Fu JY, Gao J, Zhang ZY, Zheng JW （通讯作者）, Luo JF, Zhong LP, Xiang YB Tea consumption and the risk of oral cancer incidence: A case-control study from China Oral Oncol 2013 49(9):918-922
Zhang SY, Zheng JW （通讯作者）, Yang C, Zhang ZY, Shen GF, Zhang JZ, Xu YJ, Cao X Case-based learning in clinical courses in a Chinese college of stomatology J Dent Educ 2012 76(10):1389-1392
张凌,郑家伟 （通讯作者） 普萘洛尔治疗婴幼儿血管瘤的作用机制研究进展 中国口腔颌面外科杂志 2012 10(4):342-348
郑家伟 （共同第一作者）,张凌,麦华明 口腔颌面部血管瘤的治疗 中华口腔医学研究杂志（电子版） 2012 6(2):1-6
中华口腔医学会口腔颌面外科专业委员会脉管性疾病学组 （通讯作者） 口腔颌面－头颈部静脉畸形诊治指南 中国口腔颌面外科杂志 2011 9(6):510-517
郑家伟 （通讯作者）,赵怡芳 平阳霉素治疗脉管性疾病规范 中国口腔颌面外科杂志 2011 9(1):68-69
Zheng JW （共同第一作者）, Zhang SY, Yang C, Zhang ZY, Shen GF Creating an effective PBL case in oral and maxillofacial surgery at a Chinese dental school: a dental education primer J Dent Educ 2011 75(11):1496-1501
中华口腔医学会口腔颌面外科专业委员会脉管性疾病学组 （通讯作者） 口腔颌面部动静脉畸形诊治指南 中国口腔颌面外科杂志 2011 9(3):242-247
Zhou Q, Zheng JW （通讯作者）, Mai HM, Luo QF, Fan XD, Su LX, Wang YA, Qin ZP Treatment guidelines of lymphatic malformations of the head and neck Oral Oncol 2011 47 (12):1105-1109
郑家伟 （通讯作者）,周琴,王延安,范新东,周国瑜,秦中平,赵吉宏,王绪凯,赵怡芳 口腔颌面部血管瘤治疗指南 中国口腔颌面外科杂志 2011 9(1):61-67
Zhou Q, Zheng JW （通讯作者）, Yang XJ, Wang HJ, Ma D, Qin ZP Detection of RASA1 mutations in patients with sporadic Sturge-Weber syndrome Childs Nerv Syst 2011 27(4):603-607
Yang XJ, Jiang YH, Zheng JW （通讯作者）, Hong L,Zhou Q, Qin ZP The role of serum basic fibroblast growth factor (bFGF), estradiol and urine bFGF in differentiating infantile hemangiomas from vascular malformations Phlebology 2011 26(5):191-196
麦华明,郑家伟 （通讯作者）,王延安 The potential role of progesterone during pregnancy as an induction of infantile hemangioma 上海口腔医学 2011 20(6):669-672
周琴,郑家伟 （通讯作者）,杨秀娟,麦华明 α-干扰素治疗婴幼儿头颈部重症血管瘤的临床评价 中国口腔颌面外科杂志 2011 9(2):130-133
Zhou Q, Zheng JW （通讯作者）, Yang XJ, Wang YA Concentration is more important than dose when using intralesional Pingyangmycin injection for treatment of vascular malformations Shanghai J Stomatol 2010 19(2):220-221
郑家伟 （共同第一作者）,李金忠,涂文勇,张陈平,郭传瑸,李龙江,孙沫逸,韩正学,廖贵清,潘朝斌,张文峰,季彤 口腔颌面部恶性肿瘤治疗指南 中国口腔颌面外科杂志 2010 8(2):98-106
周琴,郑家伟 （通讯作者） Sturge-Weber综合征病理生理学研究进展 中国口腔颌面外科杂志 2009 7(5):470-475
周琴,郑家伟 （通讯作者） Klippel-Trenaunay综合征治疗进展 口腔颌面外科杂志 2009 19(4):296-300
Yang XJ, Zheng JW （通讯作者）, Zhou Q, Ye Wm, Wang YA, Zhu HG, Zhang ZY A possible mechanism of spontaneous involution of infantile hemangioma Bioscience Hypotheses(SCI)(MEDLINE) 2009 2(3):182-183
Wang YA, Zhang ZY, Zheng JW （通讯作者）, Ye WM, Wang LZ, Zhu HG Spontaneous thoracic duct cyst presenting as a left supraclavicular mass - report of a case and review of literature Phlebology(SCI)(MEDLINE) 2009 24(2):82-84
Zheng JW, Zhou Q, Yang XJ, He Y, Wang YA, Ye WM, Zhu HG, Zhang ZY Intralesional injection of Pingyangmycin may be an effective treatment for epulis Med Hypotheses(SCI) (MEDLINE) 2009 72(4):453-454
郑家伟,钟来平,张志愿 口腔癌的预防 中国口腔颌面外科杂志 2009 7(2):168-175
Fan XD, Su LX, Zheng JW （通讯作者）, Zheng LZ, Zhang ZY Ethanol Embolization of AVM in the mandible AJNR Am J Neuroradiol (SCI) 2009 30(6):1178-1183
Zheng JW, Yang XJ, Wang YA, He H, Ye WM, Zhang ZY Intralesional injection of Pingyangmycin for vascular malformations in oral and maxillofacial regions: an evaluation of 297 consecutive patients Oral Oncol(SCI)(MEDLINE) 2009 45(10):872-876
袁荣涛,郑家伟 （通讯作者）,李宁毅 颈动脉体瘤与SDH基因突变的研究进展 中国口腔颌面外科杂志 2009 7(3):281-283
Zheng JW, Yang XJ, Zhou Q, Wang YA, Su LX, Ye WM, Zhu HG, Zhang ZY The role of multipotential stem cells in human infantile hemangioma Bioscience Hypotheses(SCI) (MEDLINE) 2009 2:46-47
Zheng JW, Yang XJ, Zhou Q, Wang YA, Ye WM, Zhu HG, Zhang ZY Short-term high-dose oral prednisone on alternate days: A more rational regime for infantile hemangiomas Med Hypotheses(SCI) (MEDLINE) 2009 72(3):365-365
郑家伟 （通讯作者）,杨秀娟 血管瘤的治疗选择 中国实用口腔科杂志 2009 2(5):267-272
Zheng JW, Zhou Q, Yang XJ, Wang YA, Ye WM, Zhu HG, Zhang ZY Anti-estrogenic agents might be more favorable option for treatment of hereditary hemorrhagic telangiectasia Med Hypotheses(SCI) (MEDLINE) 2009 72(2):230-231
Zhou Q, Zheng JW （通讯作者）, Yang XJ, Wang YA, Ye WM, Zhu HG, Zhang ZY Fibronectin: characterization of a somatic mutation in Sturge-Weber Syndrome (SWS) Med Hypotheses(SCI)(MEDLINE) 2009 73(2):199-200
Yang XJ, Zheng JW （通讯作者）, Ye WM, Wang YA, Zhu HG, Wang LZ, Zhang ZY Malignant solitary fibrous tumours of the head and neck: A clinicopathological study of 9 consecutive patients Oral Oncol(SCI) (MEDLINE) 2009 45(8):678-682
Zheng JW, Zhong LP, Ye WM, Zhang ZY Autologous external jugular vein: A potential vascular graft for carotid artery reconstruction Med Hypotheses(SCI) (MEDLINE) 2009 72(5): 551-552
周琴,郑家伟 （通讯作者） 颈动脉体瘤分子生物学研究进展 上海口腔医学 2009 18(2):218-222
杨秀娟,郑家伟 （通讯作者）,洪莉,周琴,秦中平 血清bFGF、E2及尿bFGF对婴幼儿血管瘤和脉管畸形的诊断意义 中国口腔颌面外科杂志 2009 7(6):482-486
Wang YA, Zheng JW （通讯作者）, Fei ZL, Jiang XQ, Wang ZG, Fei J, Zhang ZY A novel transgenic mice model for venous malformation Transgenic Res(SCI) (MEDLINE) 2009 18(2):193-201
Wang YA, Fei ZL, Zhang ZY, Jiang XQ, Chen WT, Wang ZG, Fei J, Zheng JW （通讯作者） Construction of novel conditional transgenic vectors for molecular therapy based on the Tet-On system and flanked with insulators in a single plasmid Molecular Medicine Reports(SCI) (MEDLINE) 2009 2(5):799-803
尚伟,陆海军,李薇,郑家伟 （通讯作者） 头颈部鳞癌发病机制与治疗研究进展 中国口腔颌面外科杂志 2009 7(3):290-297
郑家伟,王延安,杨秀娟,周琴 The clinical significance of bimodal growth pattern in the treatment of hemangiomas in infancy and children 上海口腔医学 2009 18(5):555-556
秦中平,刘学键,李克雷,周琴,杨秀娟,郑家伟 （通讯作者） 小剂量普萘洛尔口服治疗婴儿血管瘤的近期疗效与安全性评价 中华医学杂志(MEDLINE) 2009 89(44): 3130-3134
Su YX, Zheng JW （共同第一作者）, Zheng GS, Liao GQ, Zhang ZY Neoadjuvant chemotherapy of PF regimen in head and neck squamous cell carcinoma: A meta-analysis Chinese Med J(SCI) (MEDLINE) 2008 121(19):1896-1901
中华口腔医学会口腔颌面外科专业委员会脉管性疾病学组 口腔颌面部血管瘤和脉管畸形治疗指南 中华医学杂志 (MEDLINE) 2008 88(44):3102-3107
Zheng JW, Zhou GY, Wang YA, Zhang ZY Management of head and neck hemangiomas in China Chinese Med J(SCI) 2008 121(11):1037-1042
郑家伟,叶为民,王延安,周国瑜,张志愿 婴幼儿血管瘤的现代治疗 上海口腔医学(MEDLINE) 2008 17(4):337-347
Li JZ, Zheng JW （共同第一作者）, Zhang ZY Evaluation of Cetuximab in combination with radiotherapy or chemotherapy against advanced squamous cell carcinoma of the head and neck Shanghai J Stomatol(MEDLINE) 2008 17(1):1-5
Li JZ, Pan HY, Zheng JW （通讯作者）, Zhou XJ, Zhang P, Chen WT, Zhang ZY Benzo (a) pyrene induced tumorigenesity of human immortalized oral epithelial cells: transcription profiling Chinese Med J(SCI) (MEDLINE) 2008 121(19):1882-1890
Zhong LP, Zheng JW （通讯作者）, Zhang WL, Zhang SY, Zhu HG, Ye WM, Wang YA, Zhang ZY Multicentric Gorham's disease in the oral and maxillofacial region: report of a case and review of the literature J Oral Maxillofac Surg(SCI) 2008 66(5):1073-1076
Jin WL, Ye WM, Zheng JW （通讯作者）, Zhou L, Zhu HG, Zhang ZY, Tian J Occult cervical lymph node metastases in 100 patients with cN0 tongue cancer Chinese Med J(SCI) (MEDLINE) 2008 121(19):1871-1874
Ye WM, Zhu HG, Zheng JW （通讯作者）, Wang XD, Zhao W, Zhong LP, Zhang ZY Use of allogenic acellular dermal matrix in prevention of Frey's syndrome after parotidectomy Br J Oral Maxillofac Surg(SCI) (MEDLINE) 2008 46(8):649-652
Zheng JW, Qiu WL, Zhang ZY Combined and sequential treatment of oral and maxillofacial malignancies: an evolving concept and clinical protocol Chinese Med J(SCI) (MEDLINE) 2008 121(19):1945-1952
周琴,郑家伟 （通讯作者） Sturge-Weber综合征研究进展 中国口腔颌面外科杂志 2008 6(3):221-226
杨秀娟,郑家伟 （通讯作者） 血管瘤与脉管畸形的鉴别诊断研究进展 上海口腔医学(MEDLINE) 2007 16(5):542-546
郑家伟,孙坚,张志愿 I型神经纤维瘤病研究进展 上海口腔医学(MEDLINE) 2007 16(6):561-569
Zheng JW, Zhong LP, Zhang ZY, Zhang CP, Zhu HG, Sun J, Fan XD, Hu YJ, Ye WM, Li J, Sun J Carotid artery resection and reconstruction: clinical experience of 28 consecutive cases Int J Oral Maxillofac Surg (SCI) 2007 36(6):514-21
王延安,张志愿,费照亮,蒋欣泉,王铸钢,郑家伟 （通讯作者） 绝缘子元件的克隆及功能验证 口腔颌面外科杂志 2007 17(4):297-300
郑家伟,李金忠,钟来平,张志愿 口腔鳞状细胞癌临床流行病学研究现状 中国口腔颌面外科杂志 2007 5(2):83-90
Zheng JW, Zhang WL, Fan XD, Zhang ZY Elongation and tortuosity of the bilateral internal carotid artery presenting as a pulsatile cervical mass: Report of a case J Oral Maxillofac Surg(SCI) 2007 65(7):1370-1372
郑家伟,王延安,周国瑜,竺涵光,叶为民,张志愿 头颈部血管瘤治疗适应证的探讨 上海口腔医学(MEDLINE) 2007 16(4):337-342
郑家伟,秦中平,张志愿,周国瑜 口服皮质激素治疗婴幼儿口腔颌面部血管瘤 中国口腔颌面外科杂志 2006 4(3):228-232
Zheng J, Zhang Z, Qin Z, Zhu H, Wang Y, Chen C Management of oral and maxillofacial vascular anomalies: the Chinese experience Phlebology Review 2006 14(5):193-209
Zheng JW, Zhu HG, Yuan RT, Li J, Wang LZ, Zhang SY, Zhang ZY Recurrent malignant carotid body tumor: report of one case and review of the literature Chin Med J (Engl) 2005 118(22):1929-1932
郑家伟,秦中平,张志愿 口腔颌面部淋巴管畸形的治疗 上海口腔医学(MEDLINE) 2005 14(6):553-556