导师姓名： 金贤 专业代码： 100201
性别： 男 专业名称： 内科学
培养单位： 附属第六人民医院 三级学科/
专业领域： 心血管病
导师类型： 硕士生导师 专业学位导师： 兼
联系方式：
邮编： 邮箱地址： jinxianian@126.com

研究方向 (点击浏览详细信息)
急性心肌梗死后损伤修复的机制

社会任职
中国医药教育协会心血管病分会青年委员会委员
上海市医学会心血管病分会委员，结构性心脏病副组长

科研项目 项目编号项目名称课题来源起止年月批准经费承担职责
** 孤核受体Nr4a1调控单核/巨噬细胞分化和极化改善糖尿病急性心肌梗死损伤修复的机制研究 国家自然科学基金-面上项目 2019-01~2022-12 57万元 课题负责人

学术论文 作者论文标题期刊名出版年卷期页码
Jin X,Liu L, Zhang Y, Xiang Y, Yin G, Lu Y, Shi L, Dong J, Shen C Advanced Glycation End Products Enhance Murine Monocyte Proliferation in Bone Marrow and Prime Them into an Inflammatory Phenotype through MAPK Signaling J Diabetes Res. 2018 2018 **
Liu L, Jin X （共同第一作者）, Hu CF, Zhang YP, Zhou Z, Li R, Shen CX Amphiregulin enhances cardiac fibrosis and aggravates cardiac dysfunction in mice with experimental myocardial infarction partly through activating EGFR-dependent pathway Basic Res Cardiol 2018 113 (2):12
Liu L, Jin X （共同第一作者）, Hu CF, Li R, Zhou Z, Shen CX Exosomes Derived from Mesenchymal Stem Cells Rescue Myocardial Ischaemia/Reperfusion Injury by Inducing Cardiomyocyte Autophagy Via AMPK and Akt Pathways Cell Physiol Biochem 2017 43(1):52-68
Jin X, Chen C, Li D, Su Q, Hang Y, Zhang P, Hu W PRDX2 in Myocyte Hypertrophy and Survival is Mediated by TLR4 in Acute Infarcted Myocardium Sci Rep 2017 7(1):6970
Zhou Z, Tang Y, Jin X （通讯作者）, Chen C, Lu Y, Liu L, Shen C Metformin Inhibits Advanced Glycation End Products-Induced Inflammatory Response in Murine Macrophages Partly through AMPK Activation and RAGE/NFkappaB Pathway Suppression. J Diabetes Res 2016 **
Liu L, Jin X （共同第一作者）, Zhou Z, Shen C Enhancement of Anti-Hypoxic Activity and Differentiation of Cardiac Stem Cells by Supernatant Fluids from Cultured Macrophages that Phagocytized Dead Mesenchymal Stem Cells. Int J Mol Sci 2016 17(7). pii: E1175.
Jin X, Liu L, Zhou Z, Ge J, Yao T, Shen C Pioglitazone alleviates inflammation in diabetic mice fed a high-fat diet via inhibiting advanced glycation end-product-induced classical macrophage activation FEBS J 2016 283 (12):2295-2308.
Jin X, Yao T, Zhou Z, Zhu J, Zhang S, Hu W, Shen C Advanced Glycation End Products Enhance Macrophages Polarization into M1 Phenotype through Activating RAGE/NF-κB Pathway. Biomed Res Int 2015 732450
Tang Y, Jin X （共同第一作者）, Xiang Y, Chen Y, Shen CX, Zhang YC, Li YG The lncRNA MALAT1 protects the endothelium against ox-LDL-induced dysfunction via upregulating the expression of the miR-22-3p target genes CXCR2 and AKT FEBS Lett 2015 589(20 Pt B):3189-3196.