导师姓名： 范存义 专业代码： 100210
性别： 男 专业名称： 外科学
培养单位： 附属第六人民医院 三级学科/
专业领域： 骨外
导师类型： 博士生导师 专业学位导师： 兼
联系方式： 上海市徐汇区宜山路600号 上海交通大学附属第六人民医院
邮编： 200233 邮箱地址： fancunyi888@163.com

研究方向 (点击浏览详细信息)
肢体复杂损伤修复与功能重建
组织粘连发生与发展机制与干预措施研究
生物材料与组织再生
异位骨化

社会任职

现任上海交通大学附属第六人民医院副院长、上海市第六人民医院东院常务副院长，上海交通大学附属第六人民医院主任医师，上海市四肢显微外科研究所副所长，上海交通大学创伤骨科研究所副所长，上海健康医学院外科学系主任。学术上担任中华医学会手外科学会常务委员，中国医师协会手外科分会副会长，上海医学会手外科学分会主任委员，上海医师协会手外科分会副会长，中国康复医学会肢残专业委员会常务委员，中国医学工程学会委员，全国外科植入物和矫形器械标准化技术委员会材料及骨科植入物分技术委员会委员，中华手外科杂志、中华创伤骨科杂志、中国矫形外科杂志、国际骨科学杂志、实用手外科杂志、美国Journal of Shoulder and Elbow Surgery、Microsurgery、Frontier in Neuroscience杂志等国内外著名学术期刊编委和特约审稿专家。

科研项目 项目编号项目名称课题来源起止年月批准经费承担职责
** 巨噬细胞极化介导的成骨破骨平衡在创伤后异位骨化中的作用及机制研究 国家自然科学基金委重点项目 2019-01~2023-12 293万元 课题负责人
PKJ2018-Y52 负载骨髓间充质干细胞的PLGA/PLLA韧带补片修复肘关节功能障碍术后侧副韧带大段缺损的机制研究 上海浦东科学技术委员会 2018-12~2021-11 20万元 课题负责人
PW2018E-01 肘关节异位骨化和功能障碍的综合防治策略 上海浦东卫生和计划生育委员会 2018-12~2021-11 100万元 课题负责人
SHDC** 肘关节功能障碍评估评价体系的建立 上海申康医院发展中心 2018-11~2021-11 50万元 课题负责人
PWZxq2017-03 骨关节炎的防治体系 上海浦东卫生和计划生育委员会 2017-10~2020-12 120万元 课题负责人
** 肘关节功能障碍综合性治疗技术的建立 上海市科学技术委员会 2017-06~2020-06 20万元 课题负责人
** NF-κB介导的巨噬细胞活化在关节粘连形成中的机制及干预研究 国家自然科学基金委面上项目 2017-01~2020-12 57万元 课题负责人
16CR3029A 系统化肘关节功能障碍治疗体系 上海申康医院发展中心 2016-12~2019-12 50万元 课题负责人
- ERK2-siRNA/聚阳离子纳米颗粒预防创伤关节粘连的机制研究 上海交通大学 “医工交叉研究基金”重点项目 2016-01~2018-12 60万元 课题负责人
－ 负载siRNA-TGF-β1/纳米颗粒的仿生腱鞘膜防治肌腱粘连的实验研究 上海市科学技术委员会优秀学术带头人计划 2014-07~2017-06 40万元 课题负责人
2013SY043 肘关节损伤与功能障碍的规范化治疗平台建设 上海市卫生和计划生育委员会 2014-01~2016-12 55万元 课题负责人
PKJ2013-Y66 肘关节功能障碍治疗方案的优化及相关研究 上海浦东科学技术委员会 2013-12~2015-12 20万元 课题负责人
PW2013D-7 肘关节功能障碍的规范化治疗 上海浦东卫生和计划生育委员会 2013-09~2016-09 14万元 课题负责人
** 负载塞来昔布的PELA纳米纤维膜防止肌腱粘连的相关机制研究 国家自然科学基金面上项目 2013-01~2016-12 68万元 课题负责人
112nm** 缓控释神经生长因子的导电高分子纳米纤维导管复合骨髓间充质干细胞促进周围神经再生的研究 上海市科学技术委员会 2013-01~2015-06 30万元 课题负责人
12DZ** PGLA周围神经导管修复周围神经缺损的临床研究 产学研医项目子课题 2012-09~2015-09 95万元 课题负责人
** 含丝素蛋白的取向纳米纤维神经导管修复周围神经缺损的机制研究 国家自然科学基金面上项目 2012-01~2015-12 59万元 课题负责人
11nm** 双向组织匹配性纳米纤维防粘连膜的研制 上海市科学技术委员会 2012-01~2014-06 40万元 课题负责人
11JC** 血管紧张素Ⅱ及受体对关节囊内粘练的作用机制研究 上海市科学技术委员会 2012-01~2014-12 30万元 课题负责人

学术论文 作者论文标题期刊名出版年卷期页码
Qian Y, Yuan WE, Cheng Y, Yang Y, Qu X, Fan C. （通讯作者） Concentrically Integrative Bioassembly of a Three-Dimensional Black Phosphorus Nanoscaffold for Restoring Neurogenesis, Angiogenesis, and Immune Homeostasis. Nano Lett 2019 19(12):8990-9001
范存义 手部骨折治疗原则与展望 中华手外科杂志 2019 35(3):161-162
Sun Z, Li J, Cui H, Ruan H, Wang W, Fan C. （通讯作者） A new pathologic classification for elbow stiffness based on our experience in 216 patients. J Shoulder Elbow Surg 2019 epub
Sun Z, Cui H, Liang J, Li J, Wang X, Fan C. （通讯作者） Determining the effective timing of an open arthrolysis for post-traumatic elbow stiffness: a retrospective cohort study. BMC Musculoskelet Disord 2019 20(1):122
王飞燕, 孙子洋, 范存义. （通讯作者） 创伤后肘关节僵硬诊治进展 国际骨科学杂志 2019 40(3):147-151
Qian Y, Yao Z, Wang X, Cheng Y, Fang Z, Yuan WE, Fan C （通讯作者）, Ouyang Y. (-)-Epigallocatechin gallate-loaded polycaprolactone scaffolds fabricated using a 3D integrated moulding method alleviate immune stress and induce neurogenesis. Cell Prolif 2019 53(1):e12730
Wang J, Cheng Y, Chen L, Zhu T, Ye K, Jia C, Wang H, Zhu M, Fan C （通讯作者）, Mo X. In vitro and in vivo studies of electroactive reduced graphene oxide-modified nanofiber scaffolds for peripheral nerve regeneration. Acta Biomater 2019 84:98-113.
Cui H, He Y, Chen S, Zhang D, Yu Y, Fan C. （通讯作者） Macrophage-Derived miRNA-Containing Exosomes Induce Peritendinous Fibrosis after Tendon Injury through the miR-21-5p/Smad7 Pathway. Mol Ther Nucleic Acids 2019 14:114-130
Qian Y, Liu W, Wang W, Fan C. （通讯作者） Obesity may be a risk factor for recurrent heterotopic ossification in post-traumatic stiff elbow among children and teenagers. Orthop Traumatol Surg Res 2019 Epub
Qian Y, Cheng Y, Cai J, Zhao X, Ouyang Y, Yuan WE, Fan C. （通讯作者） Advances in electrical and magnetic stimulation on nerve regeneration. Regen Med 2019 14(10):969-979
Cui HM, Yu YL, He Y, Kong LZ, Fan CY. （通讯作者） Management of elbow dysfunction associated with giant cell tumor of the distal humerus: achieving oncologic safety and good function by a combined reconstruction. J Shoulder Elbow Surg 2019 28(1):120-125
阮基浩, 陈帅, 范存义 （通讯作者） 关节腔注射治疗骨关节炎载药体系的研究进展 中华骨与关节外科杂志 2019 12(7):551-555
Ouyang Y, Wang W, Tu B, Zhu Y, Fan C, Li Y. Overexpression of SOX9 alleviates the progression of human osteoarthritis in vitro and in vivo Drug Des Devel Ther 2019 13:2833-2842
Yao Z, Wang W, Ning J, Zhang X, Zheng W, Qian Y, Fan C. （通讯作者） Hydroxycamptothecin Inhibits Peritendinous Adhesion via the Endoplasmic Reticulum Stress-Dependent Apoptosis. Front Pharmacol 2019 10:967
Sun Z, Liu W, Wang W, Fan C. （通讯作者） Development and validation of a new elbow-specific scoring system for patients with elbow stiffness: the Shanghai Elbow Dysfunction Score. J Shoulder Elbow Surg 2019 28(2):296-303
孙子洋, 王飞燕, 崔昊旻, 郁诗阳, 陈帅, 熊浩, 王伟, 范存义 （通讯作者） 开放性肘关节松解术治疗创伤后肘关节僵硬的现状与展望 中华创伤骨科杂志 2019 21(8):727-732
Cui H, Sun Z, Ruan J, Yu Y, Fan C. （通讯作者） Effect of enhanced recovery after surgery (ERAS) pathway on the postoperative outcomes of elbow arthrolysis: A randomized controlled trial. Int J Surg 2019 68:78-84
Sun Z, Wang W, Fan C. （通讯作者） Tobacco use predicts poorer clinical outcomes and higher post-operative complication rates after open elbow arthrolysis. Arch Orthop Trauma Surg 2019 139(7):883-891
钱运, 范存义. （通讯作者） 石墨烯促进周围神经再生的研究进展 中华手外科杂志 2019 35(2):158-160
Yao Z, Zheng W, Zhang X, Xiong H, Qian Y, Fan C. （通讯作者） Hydroxycamptothecin Prevents Fibrotic Pathways in Fibroblasts In Vitro. IUBMB Life 2019 71(5):653-662
Qian Y, Han Q, Zhao X, Li H, Yuan WE, Fan C. （通讯作者） Asymmetrical 3D Nanoceria Channel for Severe Neurological Defect Regeneration. iScience 2019 12:216-231
Qian Y, Han Q, Liu W, Yuan WE, Fan C. （通讯作者） Characteristics and management of bone and joint tuberculosis in native and migrant population in Shanghai during 2011 to 2015. BMC Infect Dis 2019 18(1):543
Sun Z, Cui H, Ruan J, Li J, Wang W, Fan C. （通讯作者） What Range of Motion and Functional Results Can Be Expected After Open Arthrolysis with Hinged External Fixation For Severe Posttraumatic Elbow Stiffness? Clin Orthop Relat Res 2019 477(10):2319–2328
Wang X, Xie L, Crane J, Zhen G, Li F, Yang P, Gao M, Deng R, Wang Y, Jia X, Fan C, Wan M, Cao X. Aberrant TGF-β activation in bone tendon insertion induces enthesopathy-like disease. J Clin Invest 2018 128(2):846-860
Qian Y, Han Q, Yuan W, Fan C. （通讯作者） Insights into medical humanities education in China and the West. J Int Med Res 2018 46(9):3507-3517
Zheng W, Song J, Sun Z, Liu J, Chen S, Fan C. （通讯作者） Effect of disease duration on functional outcomes and complications after arthrolysis in patients with elbow stiffness. J Shoulder Elbow Surg 2018 27(3):381-386
Wu R, Ruan J, Sun Y, Liu M, Sha Z, Fan C （通讯作者）, Wu Q. Long non-coding RNA HIF1A-AS2 facilitates adipose-derived stem cells (ASCs) osteogenic differentiation through miR-665/IL6 axis via PI3K/Akt signaling pathway. Stem Cell Res Ther 2018 9(1):348
Liu S, Wu F, Gu S, Wu T, Chen S, Chen S, Wang C, Huang G, Jin T, Cui W, Sarmento B, Deng L, Fan C. （通讯作者） Gene Silencing via PDA/ERK2-siRNA-Mediated Electrospun Fibers for Peritendinous Antiadhesion. Adv Sci (Weinh) 2018 6(2):**
Wang X, Li F, Xie L, Crane J, Zhen G, Mishina Y, Deng R, Gao B, Chen H, Liu S, Yang P, Gao M, Tu M, Wang Y, Wan M, Fan C, Cao X. Inhibition of overactive TGF-β attenuates progression of heterotopic ossification in mice. Nat Commun 2018 9(1):551
刘家志, 陈帅, 范存义. （通讯作者） 开放松解术联合桡骨远端固定铰链式外固定支架治疗肘关节僵硬 中国修复重建外科杂志 2018 32(2):134-138
孙子洋, 王伟, 刘文军, 范存义. （通讯作者） 肘关节相关临床评分系统应用于肘关节功能障碍的现状和展望 中华创伤骨科杂志 2018 20(10):916-920
Qian Y, Han Q, Wang W, Ouyang Y, Yuan W, Fan C. （通讯作者） Surgical release for tubercular elbow stiffness. Infect Drug Resist 2018 11:9-16
Sun Z, Xiong H, Fan C. （通讯作者） Impact of different glucose metabolism status on clinical outcomes of open arthrolysis for post-traumatic elbow stiffness. J Shoulder Elbow Surg 2018 27(6):1072-1077
程嫄, 王飞燕, 范存义. （通讯作者） 肘关节尺侧副韧带损伤和修复重建的研究进展 国际骨科学杂志 2018 39(4):205-209
Zheng W, Chen C, Chen S, Fan C （通讯作者）, Ruan H. Integrated analysis of long non-coding RNAs and mRNAs associated with peritendinous fibrosis. J Adv Res 2018 15:49-58
Cui HM, Yu YL, He Y, Cheng Y, Liu JZ, Zheng W, Chen S, Fan CY. （通讯作者） Management of elbow stiffness after postoperative treatment of terrible triad elbow injury: maintaining mobility and stability using a combined protocol. Int Orthop 2018 42(3):609-618
Sun Z, Fan C. （通讯作者） Validation of the Liverpool Elbow Score for evaluation of elbow stiffness. BMC Musculoskelet Disord 2018 19(1):302
Qian Y, Liu WJ, Wang W, Fan CY. （通讯作者） Structural Restoration of the Medial Collateral Ligament Using Cubital Tunnel Retinaculum in Stiff Elbow Instability. Chin Med J (Engl) 2018 131(21):2608-2610
Zheng W, Qian Y, Chen S, Ruan H, Fan C. （通讯作者） Rapamycin Protects Against Peritendinous Fibrosis Through Activation of Autophagy. Front Pharmacol 2018 9:402
Qian Y, Han Q, Zhao X, Song J, Cheng Y, Fang Z, Ouyang Y, Yuan WE, Fan C. （通讯作者） 3D melatonin nerve scaffold reduces oxidative stress and inflammation and increases autophagy in peripheral nerve regeneration. J Pineal Res 2018 65(4):e12516
Qian Y, Song J, Zhao X, Chen W, Ouyang Y, Yuan W, Fan C. （通讯作者） 3D Fabrication with Integration Molding of a Graphene Oxide/Polycaprolactone Nanoscaffold for Neurite Regeneration and Angiogenesis. Adv Sci (Weinh) 2018 5(4):**
Yu S, Chen M, Fan C （通讯作者） Team Approach: Elbow Contracture Due to Heterotopic Ossification. JBJS Rev 2017 5(1)
Song J, Ouyang Y, Che J, Li X, Zhao Y, Yang K, Zhao X, Chen Y, Fan C, Yuan W. （通讯作者） Potential Value of miR-221/222 as Diagnostic, Prognostic, and Therapeutic Biomarkers for Diseases. Front Immunol 2017 8:56
Chen S, Liu J, Cai J, Zheng W, Li Z, Chen W, Fan C. （通讯作者） Results and outcome predictors after open release of complete ankylosis of the elbow caused by heterotopic ossification. Int Orthop 2017 41(8):1627-1632
Cheng DD, Lin HC, Li SJ, Yao M, Yang QC, Fan CY. （通讯作者） CSE1L interaction with MSH6 promotes osteosarcoma progression and predicts poor patient survival. Sci Rep 2017 7:46238.
陈伟, 钱运, 王伟 （通讯作者）, 范存义. 肘关节假体周围感染诊治进展 国际骨科学杂志 2017 38(6):349-352
Zheng W, Song J, Zhang Y, Chen S, Ruan H, Fan C. （通讯作者） Metformin prevents peritendinous fibrosis by inhibiting transforming growth factor-β signaling. Oncotarget 2017 8(60):101784-101794
Kopka M, Monument MJ, Befus AD, Zhang M, Hart DA, Salo PT, Schneider PS, Fan CY, Liang X, Garven A, Hildebrand KA. （通讯作者） Serum Mast Cell Tryptase as a Marker of Posttraumatic Joint Contracture in a Rabbit Model. J Orthop Trauma 2017 31(3):e86-e89
Zheng W, Chen S, Song J, Liu J, Fan C. （通讯作者） The influence of body mass index on outcome of open arthrolysis for post-traumatic elbow stiffness. J Shoulder Elbow Surg 2017 26(5):809-814
Cheng DD, Li J, Li SJ, Yang QC, Fan CY. （通讯作者） CNOT1 cooperates with LMNA to aggravate osteosarcoma tumorigenesis through the Hedgehog signaling pathway. Mol Oncol 2017 11(4):388-404
Liu S, Chen H, Wu T, Pan G, Fan C, Xu Y, Cui W. （通讯作者） Macrophage infiltration of electrospun polyester fibers. Biomater Sci 2017 5(8):1579-1587
Song JL, Zheng W, Chen W, Qian Y, Ouyang YM, Fan CY. （通讯作者） Lentivirus-mediated microRNA-124 gene-modified bone marrow mesenchymal stem cell transplantation promotes the repair of spinal cord injury in rats. Exp Mol Med 2017 49(5):e332
Cheng DD, Zhang HZ, Yuan JQ, Li SJ, Yang QC, Fan CY. （通讯作者） Minichromosome maintenance protein 2 and 3 promote osteosarcoma progression via DHX9 and predict poor patient prognosis. Oncotarget 2017 8(16):26380-26393
Chen S, Jiang S, Zheng W, Tu B, Liu S, Ruan H, Fan C. （通讯作者） RelA/p65 inhibition prevents tendon adhesion by modulating inflammation, cell proliferation, and apoptosis. Cell Death Dis 2017 8(3):e2710
Zhou Y, Cai JY, Chen S, Liu S, Wang W, Fan CY. （通讯作者） Application of distal radius-positioned hinged external fixator in complete open release for severe elbow stiffness. J Shoulder Elbow Surg 2017 26(2):e44-e51
Wang W, Zhan YL, Yu SY, Zheng XY, Liu S, Fan CY. （通讯作者） Open arthrolysis with pie-crusting release of the triceps tendon for treating post-traumatic contracture of the elbow. J Shoulder Elbow Surg. 2016 25(5):816-22
夏震, 刘珅, 范存义. （通讯作者） 肘关节功能障碍245例疗效及病因分析 中华手外科杂志 2016 32(3):162-164
Sun Y, Cai J, Yu S, Chen S, Li F, Fan C. （通讯作者） MiR-630 Inhibits Endothelial-Mesenchymal Transition by Targeting Slug in Traumatic Heterotopic Ossification. Sci Rep 2016 6:22729
Tu B, Liu S, Liu G, Li Z, Sun Y, Fan C. （通讯作者） Inhibition of connexin 43 prevents trauma-induced heterotopic ossification. Sci Rep 2016 6:37184
Tu B, Liu S, Yu B, Zhu J, Ruan H, Tang T, Fan C. （通讯作者） miR-203 inhibits the traumatic heterotopic ossification by targeting Runx2. Cell Death Dis 2016 7(10):e2436
阮洪江, 范大鹏, 陈帅, 李旭军, 范存义. （通讯作者） miRNA219-5P靶向调控Smad4表达影响TGF-β1诱导肌腱成纤维细胞纤维化的研究 中国修复重建外科杂志 2016 30(5):641-646
李岩峰, 孙源, 蔡培华, 范存义. （通讯作者） 指固有神经卡压综合征15例 中华手外科杂志 2016 32(6):453-454
Song J, Chen Y, Jiang S, Yang K, Li X, Zhao X, Ouyang Y, Fan C, Yuan W. （通讯作者） Efficient and Non-Toxic Biological Response Carrier Delivering TNF-α shRNA for Gene Silencing in a Murine Model of Rheumatoid Arthritis. Front Immunol 2016 7:305
Song J, Sun B, Liu S, Chen W, Zhang Y, Wang C, Mo X, Che J, Ouyang Y, Yuan W, Fan C. （通讯作者） Polymerizing Pyrrole Coated Poly (l-lactic acid-co-ε-caprolactone) (PLCL) Conductive Nanofibrous Conduit Combined with Electric Stimulation for Long-Range Peripheral Nerve Regeneration. Front Mol Neurosci 2016 9:117
Cai J, Zhou Y, Chen S, Sun Y, Yuanming O, Ruan H, Fan C. （通讯作者） Ulnar neuritis after open elbow arthrolysis combined with ulnar nerve subcutaneous transposition for post-traumatic elbow stiffness: outcome and risk factors. J Shoulder Elbow Surg 2016 25(6):1027-33
Fan D, Liu S, Jiang S, Li Z, Mo X, Ruan H, Zou GM, Fan C. （通讯作者） The use of SHP-2 gene transduced bone marrow mesenchymal stem cells to promote osteogenic differentiation and bone defect repair in rat. J Biomed Mater Res A 2016 104(8):1871-81
Chen S, Yan H, Wang W, Zhang M, Hildebrand KA, Fan CY. （通讯作者） Reconstruction of medial collateral ligament defects with a flexor-pronator fascia patch in complete open release of stiff elbows. J Shoulder Elbow Surg 2016 26(1):133-139
Cai JY, Wang W, Yu SY, Yan HD, Zhan YL, Fan CY*. （通讯作者） Chronic Post-traumatic Dislocation of Radial Head with Ulnar Nerve Entrapment in a Child: A Case Report and Literature Review. Ann Plas Surg 2016 76(6):659-62.
黎之惟, 王伟, 陈伟, 范存义. （通讯作者） 桡骨头置换术研究进展 国际骨科学杂志 2016 37(6):363-367
Fan D, Wang W, Hildebrand KA, Fan CY. （通讯作者） Open arthrolysis for elbow stiffness increases carrying angle but has no impact on functional recovery. BMC Musculoskelet Disord 2016 17(1):388
Sun Y, Li F, Fan C. （通讯作者） Effect of pERK2 on extracellular matrix turnover of the fibrotic joint capsule in a post-traumatic joint contracture model. Exp Ther Med 2016 11(2):547-552
Cai JY, Zhou Y, Chen S, Sun YB, Ouyang YM, Ruan HJ, Fan CY. （通讯作者） Ulnar neuritis after open elbow arthrolysis combined with ulnar nerve subcutaneous transposition for post-traumatic elbow stiffness: outcome and risk factors. J Shoulder Elb Surg 2016 25(6):1027-33
Wang W, Yu J, Fan CY, Liu S, Zheng X （通讯作者） Stability of the distal phalanx fracture - A biomechanical study on the importance of the nail and the influence of fixation by crossing Kirschner wires. Clin Biomech (Bristol, Avon) 2016 37:137-140
Li L, Zheng X, Fan D, Yu S, Wu D, Fan C, Cui W, Ruan H. （通讯作者） Release of celecoxib from a bi-layer biomimetic tendon sheath to prevent tissue adhesion. Mater Sci Eng C Mater Biol Appl 2016 61:220-6
Li L, Zheng X, Fan D, Yu S, Wu D, Fan C, Cui W, Ruan H. （通讯作者） Release of celecoxib from a bi-layer biomimetic tendon sheath to prevent tissue adhesion. Mater Sci Eng C Mater Biol Appl 2016 61:220-6
Lin D, Zhang J, Bai F, Cao X, Fan C, Yuan Y, Wang J, Zhang J, Liu C. （通讯作者） Fabrication and clinical application of easy-to-operate pre-cured CPC/rhBMP-2 micro-scaffolds for bone regeneration. Am J Transl Res 2016 8(3):1379-96
Cai J, Wang W, Yu S, Yan H, Zhan Y, Fan C. （通讯作者） Chronic Posttraumatic Dislocation of Radial Head With Ulnar Nerve Entrapment in a Child: A Case Report and Literature Review. Ann Plast Surg 2016 76(6):659-62
Tu B, Zhu J, Liu S, Wang L, Fan Q, Hao Y, Fan C, Tang TT. （通讯作者） Mesenchymal stem cells promote osteosarcoma cell survival and drug resistance through activation of STAT3. Oncotarget 2016 7(30):48296-48308
Wang W, Zhan YL, Yu SY, Zheng XY, Liu S, Fan CY. （通讯作者） Open arthrolysis with pie-crusting release of the triceps tendon for treating posttraumatic contracture of the elbow J Shoulder Elb Surg 2016 25(5):816-22
Chen W, Chen S, Morsi Y, El-Hamshary H, El-Newhy M, Fan C, Mo X （通讯作者） Superabsorbent 3D Scaffold Based on Electrospun Nanofibers for Cartilage Tissue Engineering. ACS Appl Mater Interfaces 2016 8(37):24415-25
Pan G, Liu S, Zhao X, Zhao J, Fan C （通讯作者）, Cui W Full-course inhibition of biodegradation-induced inflammation in fibrous scaffold by loading enzyme-sensitive prodrug Biomaterials 2015 53:202-10
Yu SY, Wang W, Liu S, Ruan HJ, Liu JJ, Li XJ, Zhan YL, Fan CY. （通讯作者） Arthrolysis and delayed internal fixation combined with hinged external fixation for elbow stiffness associated with malunion or nonunion of capitellum fracture. J Shoulder Elbow Surg 2015 24(6):941-6
Wang W, Liu S, Jiang SC, Ruan HJ, He N, Fan CY （通讯作者） Limited Medial and Lateral Approaches to Treat Stiff Elbows Orthopedics 2015 38(6):e477-84
Huang C, Ouyang Y, Niu H, He N, Ke Q, Jin X, Li D, Fang J, Liu W, Fan C （通讯作者）, Lin T. Nerve guidance conduits from aligned nanofibers: improvement of nerve regeneration through longitudinal nanogrooves on a fiber surface. ACS Appl Mater Interfaces 2015 7(13):7189-96
Yu SY, Chen S, Yan HD, Fan CY （通讯作者） Effect of cryotherapy after elbow arthrolysis: a prospective, single-blinded, randomized controlled study Arch Phys Med Rehabil 2015 96(1):1-6
Yu SY, Yan HD, Ruan HJ, Wang W, Fan CY （通讯作者） Comparative study of radial head resection and prosthetic replacement in surgical release of stiff elbows. Int Orthop 2015 39(1):73-9
Tu B, Liu S, Liu G, Yan W, Wang Y, Li Z, Fan C （通讯作者） Macrophages derived from THP-1 promote the osteogenic differentiation of mesenchymal stem cells through the IL-23/IL-23R/β-catenin pathway Exp Cell Res 2015 339(1):81-9
Jiang S, Yan H, Fan D, Song J, Fan C. （通讯作者） Multi-layer electrospun membrane mimicking tendon sheath for prevention of tendon adhesions. Int J Mol Sci 2015 16(4):6932-44
Cai J, Wang W, Yan H, Sun Y, Chen W, Chen S, Fan C （通讯作者） Complications of Open Elbow Arthrolysis in Post-Traumatic Elbow Stiffness: A Systematic Review PLoS One 2015 10(9):e**
Chen S, Yu SY, Yan H, Cai JY, Ouyang Y, Ruan HJ, Fan CY （通讯作者） The time point in surgical excision of heterotopic ossification of post-traumatic stiff elbow: recommendation for early excision followed by early exercise. J Shoulder Elbow Surg 2015 24(8):1165-71
Sun Y, Cai J, Li F, Liu S, Ruan H, Fan C （通讯作者） The efficacy of celecoxib in preventing heterotopic ossification recurrence after open arthrolysis for post-traumatic elbow stiffness in adults J Shoulder Elbow Surg 2015 24(11):1735-40
Yan H, Zhang F, Wang C, Xia Z, Mo X, Fan C. （通讯作者） The role of an aligned nanofiber conduit in the management of painful neuromas in rat sciatic nerves. Ann Plast Surg 2015 74(4):454-61
Liu S, Wu J, Liu X, Chen D, Bowlin GL, Cao L, Lu J, Li F, Mo X, Fan C. （通讯作者） Osteochondral regeneration using an oriented nanofiber yarn-collagen type I/hyaluronate hybrid/TCP biphasic scaffold. J Biomed Mater Res A 2015 103(2):581-92
Zhao X, Jiang S, Liu S, Chen S, Lin ZY, Pan G, He F, Li F, Fan C （通讯作者）, Cui W. Optimization of intrinsic and extrinsic tendon healing through controllable water-soluble mitomycin-C release from electrospun fibers by mediating adhesion-related gene expression Biomaterials 2015 61:61-74
Wang W, Liu S, Jiang SC, Ruan HJ, He N, Fan CY. （通讯作者） Limited Medial and Lateral Approaches to Treat Stiff Elbows. Orthopedics 2015 38(6):e477-84
Yan H, He J, Chen S, Yu S, Fan C （通讯作者） Intrawound application of vancomycin reduces wound infection after open release of post-traumatic stiff elbows： a retrospective comparative study J Shoulder Elbow Surg 2014 23(5):686-92
Jiang S, Zhao X, Chen S, Pan G, Song J, He N, Li F, Cui W, Fan C. （通讯作者） Down-regulating ERK1/2 and SMAD2/3 phosphorylation by physical barrier of celecoxib-loaded electrospun fibrous membranes prevents tendon adhesions. Biomaterials 2014 35(37):9920-9
Kuihua Z, Chunyang W, Cunyi F （通讯作者）, Xiumei M. Aligned SF/P（LLA-CL）-blended nanofibers encapsulating nerve growth factor for peripheral nerve regeneration J Biomed Mater Res A 2014 102(8):2680-91
Wang W, Jiang SC, Liu S, Ruan HJ, Fan CY （通讯作者） Stability of severely stiff elbows after complete open release： treatment by ligament repair with suture anchors and hinged external fixator J Shoulder Elbow Surg 2014 23(10):1537-44
Wang X, Zhu Y, Tao H, Jin C, Liu Y, Lu X, Hu X, Fan C Interaction of ERK1/2 and Smad2/3 signaling pathways in TGF-β1-induced TIMP-3 expression in rat chondrocytes Arch Biochem Biophys 2014 564:229-36.
Shuai C, Hede Y, Shen L, Yuanming O, Hongjiang R, Cunyi F. （通讯作者） Is routine ulnar nerve transposition necessary in open release of stiff elbows? Our experience and a literature review Int Orthop 2014 38(11):2289-94
Chen S, Wang G, Wu T, Zhao X, Liu S, Li G, Cui W, Fan C. （通讯作者） Silver Nanoparticles/Ibuprofen-Loaded Poly( l-lactide) Fibrous Membrane: Anti-Infection and Anti-Adhesion Effects Int J Mol Sci 2014 15(8):14014-25
Yan H, Zhang F, Kolkin J, Wang C, Xia Z, Fan C. （通讯作者） Mechanisms of Nerve Capping Technique in Prevention of Painful Neuroma Formation PLoS One. 2014 9(4):e93973.
Wang W, Liu JJ, Liu S, Ruan HJ, Li XJ, Fan CY. （通讯作者） Arthrolysis combined with reconstruction for treatment of terrible triad injury with a poor outcome after surgical as well as conservative intervention. Arch Orthop Trauma Surg 2014 134(3):325-31
Li F, Liu S, Fan C （通讯作者） Lentivirus-Mediated ERK2 siRNA Reduces Joint Capsule Fibrosis in a Rat Model of Post-Traumatic Joint Contracture Int J Mol Sci 2013 14(10):20833-44
Liu S, Hu C, Li F, Li XJ, Cui W, Fan C. （通讯作者） Prevention of Peritendinous Adhesions with Electrospun Ibuprofen-Loaded Poly（L-Lactic Acid）-Polyethylene Glycol Fibrous Membranes Tissue Eng Part A 2013 19(3-4):529-37
Liu S, Qin M, Hu C, Wu F, Cui W, Jin T, Fan C （通讯作者） Tendon healing and anti-adhesion properties of electrospun fibrous membranes containing bFGF loaded nanoparticles. Biomaterials 2013 34(19):4690-701
Ruan HJ, Liu S, Fan CY （通讯作者）, Liu JJ Open arthrolysis and hinged external fixation for posttraumatic ankylosed elbows Arthives Of Orthopaedic and Trauma Surgery 2013 133(2):179-85
Liu S, Liu JJ, Li XJ, Ruan HJ, Fan CY （通讯作者） Open arthrolysis and prosthetic replacement of the radial head for elbow stiffness associated with ratation limitation J Shoulder Elbow Surg 2013 22(2):275-9
Yan H, Kolkin J, Zhao B, Li Z, Jiang S, Wang W, Xia Z, Fan C （通讯作者） The Effect of Hemodynamic Remodeling on the Survival of Arterialized Venous Flaps PLoS One 2013 8(11):e79608
Jiang S, Wang W, Yan H, Fan C （通讯作者） Prevention of intra-abdominal adhesion by bi-layer electrospun membrane Int J Mol Sci 2013 14(6):11861-70
Ouyang Y, Huang C, Zhu Y, Fan C （通讯作者）, Ke Q Fabrication of Seamless Electrospun Collagen/PLGA Conduits Whose Walls Comprise Highly Longitudinal Aligned Nanofibers for Nerve Regeneration J Biomed Nanotechnol 2013 9(6):931-43.
Yan H, Gao W, Li Z, Wang C, Liu S, Zhang F, Fan C （通讯作者） The management of degloving injury of lower extremities： technical refinement and classification. J Trauma Acute Care Surg 2013 74(2):604-10
Li F, He B, Liu S, Fan C. （通讯作者） Celecoxib effectively inhibits the formation of joint adhesions Exp Ther Med 2013 6(6):1507-1511
Yan H, Liu S, Gao W, Li Z, Chen X, Wang C, Zhang F, Fan C. （通讯作者） Management of degloving injuries of the foot with a defatted full-thickness skin graft. J Bone Joint Surg Am 2013 95(18):1675-81
Liu S, Zhao J, Ruan H, Wang W, Wu T, Cui W, Fan C （通讯作者） Antibacterial and anti-adhesion effects of the silver nanoparticles-loaded poly(L-lactide) fibrous membrane Mater Sci Eng C Mater Biol Appl 2013 33(3):1176-82
Liu S, Jin F, Lin K, Lu J, Sun J, Chang J, Dai K, Fan C （通讯作者） The effect of calcium silicate on in vitro physiochemical properties and in vivo osteogenisis, degradability and bioactivity of porous β- tricalcium phosphate bioceramics Biomedical Materials 2013 8(2):025008
S Liu, S Liu, X Liu, J Zhao, W Cui, C Fan （通讯作者） Antibacterial antiadhesion membranes from silver-nanoparticle-doped electrospun poly（L-lactide） nanofibers Journal Of Applied Polymer Science 2013 129(6):3459–3465
Ouyang Y, Liao Y, Liu Z, Fan C （通讯作者） Hinged external fixator and open surgery for severe elbow stiffness with distal humeral nonunion Orthopedics 2013 36(2):e186-92.
Ruan H, Liu S, Li F, Li X, Fan C （通讯作者） Prevention of Tendon Adhesions by ERK2 Small Interfering RNAs Int J Mol Sci 2013 14(2):4361-71
Yan H, Fan C （通讯作者）, Zhang F, Gao W, Li Z, Zhang X Reconstruction of large dorsal digital defects with arterialized venous flaps: our experience and comprehensive review of literature. Annals of Plastic Surgery 2013 70(6):666-71
Ouyang Y, Wang Y, Fan C （通讯作者）, Liu Z, Liu S, Li F Using the contralateral reverse less invasive plating system for subtrochanteric femur fractures in elderly patients Medical principles and practice 2012 21(4):334-339
Ouyang Y, Wang Y, Li F, Fan C. （通讯作者） Open release and a hinged external fixator for the treatment of elbow stiffness in young patients Orthopedics 2012 35(9):1365-1370
Wang CY, Liu JJ, Fan CY （通讯作者）, Mo XM, Ruan HJ, Li FF. The effect of aligned core-shell nanofibres delivering NGF on the promotion of sciatic nerve regeneration J Biomater Sci Polym Ed 2012 23(1-4):167-184
Yan H, Ouyang Y, Chi Z, Gao W, Zhang F, Fan C （通讯作者） Digital pulp reconstruction with free neurovascular toe flaps Aesthetic plastic surgery 2012 36(5):1186-1193
Yan H, Gao W, Zhang F, Li Z, Chen X, Fan C （通讯作者） A comparative study of finger pulp reconstruction using arterialised venous sensate flap and insensate flap from forearm J Plast Reconstr Aesthet Surg 2012 65(9):1220-1226
Yan H, Fan C （通讯作者）, Gao W, Chen Z, Li Z, Chi Z Finger pulp reconstruction with free flaps from the upper extremity Microsurgery 2012 32(5):406-414
Li F, Fan C （通讯作者）, Zeng B, Zhang C, Chai Y, Liu S, Ouyang Y Effects and relationship of ERK1 and Celecoxib suppresses fibroblast proliferation and collagen expression by inhibiting ERK1/2 and SMAD2/3 phosphorylation Molecular medicine reports 2012 5(3):827-831
Liu S, Zhao J, Ruan H, Tang T, Liu G, Yu D, Cui W, Fan C （通讯作者） Biomimetic sheath membrane via electrospinning for antiadhesion of repaired tendon Biomacromolecules 2012 13(11):3611-3619
Li F, Liu S, Ouyang Y, Fan C （通讯作者）, Wang T, Zhang C, Zeng B, Chai Y, Wang X Effect of celecoxib on proliferation, collagen expression, ERK1/2 and SMAD2/3 phosphorylation in NIH/3T3 fibroblasts European journal of pharmacology 2012 678(1-3):1-5
Yan H, Gao W, Pan Z, Zhang F, Fan C （通讯作者） The Expression of alpha-SMA in the Painful Traumatic Neuroma: Potential Role in the Pathobiology of Neuropathic Pain Journal of neurotrauma 2012 29(18):2791-2797
Liu S, Liu JJ, Liu SH, Cai ZD, Chung K, Fan CY （通讯作者） Arcus venosus dorsalis pedis graft to restore the superficial palmar arch in devascularized hands J Reconstr Microsurg 2012 28(4):251-256
Wang X, Li F, Fan C （通讯作者）, Wang C, Ruan H Effects and relationship of ERK1 and ERK2 in interleukin-1beta-induced alterations in MMP3, MMP13, type II collagen and aggrecan expression in human chondrocytes Int J Mol Med 2011 27(4):583-589
Liu JJ, Wang CY, Wang JG, Ruan HJ, Fan CY （通讯作者） Peripheral nerve regeneration using composite poly(lactic acid-caprolactone)/nerve growth factor conduits prepared by coaxial electrospinning J Biomed Mater Res A 2011 96(1):13-20
Liu S, Fan CY （通讯作者）, Ruan HJ, Li FF, Tian J Combination of arthrolysis by lateral and medial approaches and hinged external fixation in the treatment of stiff elbow. J Trauma 2011 70(2):373-376
Wang CY, Zhang KH, Fan CY （通讯作者）, Mo XM, Ruan HJ, Li FF Aligned natural-synthetic polyblend nanofibers for peripheral nerve regeneration Acta Biomater 2011 7(2):634-643
Wang X, Li F, Fan C （通讯作者）, Wang C, Ruan H Analysis of isoform specific ERK signaling on the effects of interleukin-1beta on COX-2 expression and PGE2 production in human chondrocytes Biochem Biophys Res Commun 2010 402(1):23-29
Li F, Cai P, Fan C （通讯作者）, Zeng B, Chai Y, Ruan H. Distally based posterior tibial artery cross-bridge flap for reconstruction of contralateral leg soft tissue defects J Reconstr Microsurg 2010 26(3):159-164
Li F, Zeng B, Fan C （通讯作者）, Chai Y, Ruan H, Cai P Distally based extended peroneal artery septocutaneous perforator cross-bridge flap without microvascular anastomoses for reconstruction of contralateral leg and foot soft tissue defects J Reconstr Microsurg 2010 26(4):243-249
Li F, Ruan H, Fan C （通讯作者）, Zeng B, Wang C, Wang X Efficient inhibition of the formation of joint adhesions by ERK2 small interfering RNAs Biochem Biophys Res Commun 2010 391(1):795-799
Fan CY, Jiang J, Zeng BF, Jiang PZ, Cai PH, Chung KC. Reconstruction of Thumb Loss Complicated by Skin Defects in the Thumb-Index Web Space by Combined Transplantation of Free Tissues. J Hand Surg [Am]. 2006 31(2):236-241.
范存义,汤林祥,吴文革 负载妥布霉素的硫酸钙治疗慢性骨髓炎及合并骨缺损的疗效评价. 中华创伤骨科杂志, 2005 28(5):421-422.