导师姓名： 李榕 专业代码： 100201
性别： 女 专业名称： 内科学
培养单位： 附属胸科医院 三级学科/
专业领域： 呼吸系病
导师类型： 硕士生导师 专业学位导师： 兼
联系方式： **
邮编： 200030 邮箱地址： lwro@hotmail.com

研究方向 (点击浏览详细信息)
肺癌的分子生物学研究

社会任职
CSCO 会员
中国医药教育协会 临床用药评价专业委员会 常务委员
上海市药理协会药物临床试验专业委员会 委员

科研项目 项目编号项目名称课题来源起止年月批准经费承担职责
** 全外显子组测序（Whole-Exome Sequencing，WES）检测NSCLC中难治性OCT4+循环肿瘤细胞的基因突变 国家自然科学基金面上项目 2018-01~2021-12 50万元 课题负责人
** 维生素D 协同顺铂促进肺腺癌细胞凋亡的机制研究 国家自然科学基金青年科学基金项目 2012-01~2014-12 22万元 课题负责人

学术论文 作者论文标题期刊名出版年卷期页码
Zhang Y, Zhang L, Li R, Chang DW, Ye Y, Minna JD, Roth JA, Han B, Wu X. Genetic variations in cancer-related significantly mutated genes and lung cancer susceptibility. Ann Oncol. 2017 28(7):1625-1630.
Li R, Gu J, Heymach JV, Shu X, Zhao L, Han B, Ye Y, Roth J, Wu X. Hypoxia pathway genetic variants predict survival of non-small-cell lung cancer patients receiving platinum-based chemotherapy. Carcinogenesis 2017 38(4):419-424.
Huang A, Li R （共同第一作者）, Zhao J, Wang X, Jin B, Niu Y, Zhang J, Jiang L, Han B. Epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors combined with chemotherapy in first-line treatment in an advanced non-small cell lung cancer patient with EGFR sensitive mutation. Thoracic Cancer 2016 7(5):614-618.
Li R, Pu X, Chang JY, Ye Y, Komaki R, Minna JD, Roth JA, Han B, Wu X. MiRNA-Related Genetic Variations Associated with Radiotherapy-Induced Toxicities in Patients with Locally Advanced Non-Small Cell Lung Cancer. PLoS One. 2016 11(3):e**.
Li R, Huang J, Ma M, Lou Y, Zhang Y, Wu L, Chang DW, Zhao P, Dong Q, Wu X, Han B. Two-stage induced differentiation of OCT4+/Nanog+ stem-like cells in lung adenocarcinoma. Oncotarget. 2016 7(42):68360-68370.
Lou Y, Li R （共同第一作者）, Liu J, Zhang Y, Zhang X, Jin B, Liu Y, Wang Z, Zhong H, Wen S, Han B. Mitofusin-2 over-expresses and leads to dysregulation of cell cycle and cell invasion in lung adenocarcinoma. Med Oncol. 2015 32(4):132
Li R, Lou Y, Zhang W, Dong Q, Han B. Vitamin D inhibition of lung adenocarcinoma cell proliferation in vitro. Tumour Biol. 2014 35(11):10953-8
Lou Y, Li R, Zhang Y, Zhong R, Pei J, Xiong L, Zhang X, Han B. XPA gene rs** single nucleotide polymorphism and lung cancer risk: a meta-analysis. Tumour Biol. 2014 35(7):6607-17
Lou, Yuqing、Li （共同第一作者）, Rong、Xiong, Liwen、Gu, Aiqin、Shi, Chunlei、Chu, Tianqing、Zhang, Xueyan、Gu, Ping、Zhong, Hua、Wen, Shaojun、*Han, Baohui NAD(P)H: quinone oxidoreductase 1 (NQO1) C609T polymorphism and lung cancer risk: a meta-analysis Tumour Biol 2013 34(6): 3967-3979
Li, R., Lou, Y., Zhang, Y., Shi, C., Xiong, L., Gu, A. and Han, B. Clinical analysis of Gefitinib in the treatment of stage IV lung adenocarcinoma with unknown EGFR gene mutations. Thoracic Cancer 2013 4(4): 433–439
Li R, Wu J, Xiong L, Han B. Lung cancer and benign lung diseases in patients with serious vitamin D deficiency in eastern China. Thoracic Cancer 2012 3(4): 303–306
Li R, Wu J, Ma M, Pei J, Song Y, Zhang X, Han B. Comparison of PG-SGA, SGA and body-composition measurement in detecting malnutrition among newly diagnosed lung cancer patients in stage IIIB/IV and benign conditions. Med Oncol. 2011 28(3): 689-696