彭金良 副研究员

电话：
邮箱：pjl76@sjtu.edu.cn
主页：地址：生物药学楼6号楼412室


个人简历 研究方向 发表论文 科研成果
教育及工作经历：
2012/10-2013/10，加州大学洛杉矶分校医学院（纳米系统研究院/Crump分子影像中心），博士后（访问****）
2007/05-至今，上海交通大学，系统生物医学研究院/MED-X研究院/药学院，助理研究员/副研究员
2002/04 - 2007/03，上海交通大学，生命科学技术学院（生物医学工程专业），博士
1998/09 - 2001/07，武汉大学，资源与环境学院（环境科学专业），硕士
1994/09 - 1998/07，武汉大学，生命学院（发育与细胞生物学专业），学士


主要研究方向：
1.生物大分子药物（基因，多肽）新型递送系统的发展与相关疾病治疗研究
2.纳米药物制剂及治疗性细胞的体内影像学示踪与分析


1. Hongfei Yu#, Jinliang Peng#, Yuhong Xu, Jiang Chang, Haiyan Li. Bioglass activated skin tissue engineering constructs for wound healing. ACS Appl Mater Interfaces. 2016, 13;8(1): 703-715. 2. Zhen Yang, Yunlong Zan, Xiujuan Zheng, Wangxi Hai, Kewei Chen, Qiu Huang*, Yuhong Xu*, Jinliang Peng*. Dynamic FDG-PET imaging to differentiate malignancies from inflammation in subcutaneous and in situ mouse model for non-small cell lung carcinoma (NSCLC). PLoS One. 2015,10(9):e**. 3. Qian Ding, Xiaofei Si, Dan Liu, Jinliang Peng, Hailing Tang, Wenqiang Sun, Mengjie Rui, Qunli Chen, Lieyi Wu, Yuhong Xu.Targeting and liposomal drug delivery to CD40L expressing T cells for treatment of autoimmune diseases. J Control Release. 2015,207:86-92. 4. Shuang Hou, Jin-sil Choi, Kuan-Ju Chen, Yang Zhang, Jinliang Peng, Mitch A. Garcia, Jue-Hua Yu, Kaushali Thakore-Shah, Tracy Ro, Jie-Fu Chen, Parham Peyda, Guoping Fan, April D. Pyle, Hao Wang, Hsian-Rong Tseng. Supramolecular nanosubstrate mediated delivery for reprogramming and transdifferentiation of Mammalian cells. Small. 2015 ,11(21):2499-504. 5. Yanzhu Yang, Qian Ding, Jian Chen, Jinliang Peng*, Yuhong Xu*. Multi-walled Carbon Nanotube Modified PLGA Scaffolds for Dendritic Cell Culture. J Biomed Mater Res A. 2015, 103(3):1045-52. 6. Hailing Tang, Xiaojing Chen, Mengjie Rui, Wenqiang Sun, Jian Chen, Jinliang Peng, Yuhong Xu. Effects of surface displayed targeting ligand GE11 on liposome distribution and extravasation in tumor. Mol Pharm. 2014,11(10): 3242-50. 7. Jinliang Peng*, Sanyuan Shi, Zhen Yang, Qian Ding, Wangxi Hai, Hailing Tang, Yanzhu Yang, James R. Bernstein, Parham Peyda, Yuhong Xu. Short-fragment DNA improves the immune response of electroporation-mediated DNA vaccination. Gene Therapy. 2014,21(7):703-708? 8. Jinliang Peng, Mitch André Garcia, Libo Zhao, Kuan-Ju Chen, James R. Bernstein, Yu-Sheng Hsiao, Katherine W. Liu, Wei-Yu Lin, Hao Wang, Shuang Hou, Hsian-Rong Tseng. Nanosubstrate-mediated delivery of genes that are encapsulated in self-assembled nanoparticles. ACS Nano. 2014,8 (5):4621–29? 9. Maoquan Chu, Yuxiang Shao, Jinliang Peng, Xiangyun Dai, Haikuo Li, Qingsheng Wu, Donglu Shi. Near-infrared laser light mediated cancer therapy by photothermal effect of Fe3O4 magnetic nanoparticles. Biomaterials. 2013;34(16): 4078-88. 10. Maoquan Chu, Jinliang Peng, Jiajia Zhao, Shanlu Liang, Yuxiang Shao, Qiang Wu. Laser light triggered-activated carbon nanosystem for cancer therapy. Biomaterials. 2013; 34(7):1820-32. ? 11. Jing Bai, Zhengyuan Zhou, Hailing Tang, Shuxian Song, Jinliang Peng, Yuhong Xu. Impact of PEGylation on biodistribution and tumor accumulation of Lipid-Mu peptide-DNA. J Liposome Res. 2013; 23(1):1-10. 12. Jinliang Peng*, Yonggang Zhao, Junhua Mai, Wei Guo, Yuhong Xu. Short noncoding DNA fragment improve efficiencies of in vivo electroporation-mediated gene transfer. J Gene Med. 2012; 14(9-10):563-9. ? 13. Maoquan Chu, Xiaojing Pan, Ding Zhang, Qiang Wu, Jinliang Peng, Waixi Hai. The therapeutic efficacy of CdTe and CdSe quantum dots for photothermal cancer therapy. Biomaterials. 2012; 33(29):7071-83.? 14. Shuxian Song, Dan Liu, Jinliang Peng, Hongwei Deng, Yan Guo, Ming Yao, Zhonghai Li, Andrew D. Miller, Lisa Xu,Yuhong Xu. Peptide ligand directed liposome drug delivery toward EGFR high-expressing cancer cells in vitro and in vivo. FASEB J. 2009,23:1396-404 15. Junhua Mai, Shuxian Song, Mengjie Rui, Dan Liu, Qian Ding, Jinliang Peng, Yuhong Xu. A synthetic peptide mediated active targeting of cisplatin liposomes to Tie2 expressing cells. J. Control Release. 2009, 139(3): 174-81 16. Shuxian Song, Dan Liu, Jinliang Peng, Ye Sun, Zonghai Li, Jian-Ren Gu and Yuhong Xu. Peptide ligand-mediated liposome distribution and targeting to EGFR expressing tumor in vivo. Int J Pharm. 2008, 363(1-2):155-61 17. Jinliang Peng, Yonggang Zhao, Wengka Pang, Junhua Mai, Wei Guo, Guangming Cheng, Guoyu Mo, Guirong Rao, Yuhong Xu. Non cytolytic antigen clearance in DNA vaccinated mice with electroporation. Acta Pharmacologica Sinica. 2007,28(7):1024-30 18. Huifeng Qian, Chaoqing Dong, Jinliang Peng, Xin Qiu, Yuhong Xu, and Jicun Ren. High-quality and water-soluble near-infrared photoluminescent CdHgTe/CdS quantum dots prepared by adjusting size and composition. J. Phys. Chem. C. 2007, 111 (45), 16852 -7 19. Yong-Gang Zhao, Huili Lu, Jinliang Peng, Long Xu, Yufeng Li, Yuhong Xu. The Inhibition Effect of Ca2+ on in vivo Gene Transfer by Electroporation. Acta Pharmacologica Sinica. 2006,27(3):307-10 20. Jinliang Peng, Yonggang Zhao, Junhua Mai, Yongjia Peng, Xiaohui Wei, Peizuo Zhang, Yuhong Xu. Inhibition of hepatitis B virus replication by various RNAi constructs and their pharmacodynamic properties. J Gen Virol. 2005;86: 3227-34.

主持包括国家自然科学基金青年项目和面上项目、863重大项目子课题、上海市自然科学基金项目、上海交通大学医工合作专项等课题。作为主要学术骨干参加“重大新药创制”科技重大专项课题、863计划生物治疗新型前沿技术及新型产品研发课题、上海市科委基础研究重点项目等研究工作。已在Gene therapy, ACS nano等SCI期刊上发表论文30余篇，申请中国发明专利7项。