邱明丰 研究员

电话：(86)-021-3420-4052
传真：(86)-021-3420-4052
邮箱：mfqiu@sjtu.edu.cn



个人简历 研究方向 发表论文 科研成果
邱明丰，男，研究员、博士生导师、博士，现任副院长、上海交通大学-西双版纳州傣医药研究中心主任、功能化DDS及新药研发课题组组长。2001年于成都中医药大学获博士学位，2003年9月从新加坡回国任职至今。长期从事中药、民族药（傣药）领域的科研与教学，致力中药、民族药（傣药）缓释与速释新型制剂及其整体疗效综合评价方法的研究。主持课题20项、参加科研项目21项（含国家自然科学基金4项、国家九五攻关、国际合作项目等），在EJPS、JEP、JPBA、ECAM、JAFC、JPR、《中国中药杂志》、《中草药》、《中成药》等杂志上发表论文126篇（含SCI 40篇，高被引论文1篇，单篇被引过百次并被Nature中文章作为亮点引用1篇），编写著作教材11部（含教材3部、主编1部、副主编5部），申请专利32项（授权9项）。主讲本科生课程4门、研究生课程3门。教学获奖近10项，包括上海交通大学首批晨星****奖励、教学成果特等奖、优秀教师二等奖等。科研获奖6项，包括中华中医药学会科技二等奖、市政府决策咨询成果二等奖等；联合研发的1类、6类和8类新药获临床批件。指导硕士生59名、博士留学生2名，学生获奖18人次（包括研究生国家奖学金、上海市优秀毕业生、校三好标兵等）。
学术兼职，包括滇西应用技术大学学术委员会委员、科技部国际合作司评审专家、教育部高等学校科学技术同行评议专家、国家自然科学基金委员会同行评议专家、世界中医药学会联合会中药药剂专业委员会理事、中国民族医药学会傣医药分会常务理事、中华中医药学会中成药分会委员、上海市药学会中药专业委员会委员、《中华医学实践杂志》常务编委、《转化医学电子杂志》编委等。


长期从事中药、民族药（傣药）领域的科研与教学，致力中药、民族药（傣药）缓释与速释新型制剂及其整体疗效综合评价方法的研究。
1、生物仿生膜系统载药（天然药物、生物大分子、化学药物）研究
2、中药、民族药（傣药）和天然药物新药研究


1.Xin Ma, Haimiao Zou, Yibin Pan, Jing Su, Yujiao Qiu，Mingfeng Qiu*.Quality assessment of pollen typhae by high-performance liquid chromatography fingerprint, hierarchical cluster analysis, and principal component analysis. Pharmacognosy Magazine, 2019, 15(61): 177.
2.Xiao Que, Jing Su, Pengcheng Guo, Zul Kamal, Enge Xu, Siyu Liu, Jieyu Chen, Mingfeng Qiu*. Study on preparation, characterization and multidrug resistance reversal of red blood cell membrane-camouflaged tetrandrine-loaded PLGA nanoparticles. Drug delivery, 2019, 26(1): 199-207.
3.Xiumei Zhang, Mingfeng Qiu, Pengcheng Guo, Yumei Lian, Enge Xu, Jing Su*.Autologous Red Blood Cell Delivery of Betamethasone Phosphate Sodium for Long Anti-Inflammation. Pharmaceutics,2018,10(4)286.
4.Jing Su,Geyi Liu, Yumei Lian ,Zul Kamal, Xiao Que, Yujiao Qiu，Mingfeng Qiu*. Preparation and Characterization of Erythrocyte Membrane Cloaked PLGA/Arsenic Trioxide Nanoparticles and Its’ in Vitro Anti-tumor Evaluation，RSC Advances.2018,8,20068-20076
5.Jing Su, Ran Zhang, Yumei Lian, Zul Kamal, Zhongyao Cheng, Yujiao Qiu, Mingfeng Qiu*. Preparation and characterization of erythrocyte membrane-camouflaged berberine hydrochloride （BH）-loaded gelatin nanoparticles. Pharmaceutics. 2019, 11(2): 93.
6.Zhongyao Cheng, Yumei Lian, Zul Kamal, Xin Ma, Jianjun Chen, Xinbo Zhou*., Jingsu*. and Mingfeng Qiu*. Nanocrystals Technology for Pharmaceutical Science. Current Pharceutical Design, 2018, 24(21):2497-2507.
7.Junwei Fang, Liping Wang, Yang Wang, Mingfeng Qiu* and Yongyu Zhang*. Metabolomics combined with pattern recognition and bioinformatics analysis methods for the development of pharmacodynamics biomarkers on live fibrosis. Molecular BioSystems，2017, 13(8): 1575-1583.
8. Yanan Sun, Jing Su,Geyi Liu, Jianjun Chen, Xiumei Zhang，Ran Zhang，Minhan Jiang，Mingfeng Qiu*. Advances of blood cell-based drug delivery systems. European Journal of Pharmaceutical Sciences.2017,96:115-128.
9.Xuelan Tang1, Ping Lu1, Mingfeng Qiu1, Jianjun Chen, Lin Ma, Yanan Sun, Feng Zheng, Enge Xu, Jing Sheng and Jing Su. Screening PEGylated polyethylenimine derivatives for safe and efficient delivery of gene materials. RSC Advances.2016,6(108):106316-106326.
10.Hongmei An, Chen Lin, Chao Gu, Jinjun Chen, Wenxian Sun, Miao Jin, Tianli Zhang, Mingfeng Qiu*, Bing Hu*. Di-Huang-Yi-Zhi herbs attenuate amyloid-induced neurotoxicity in PC12 cells. Experimental and Therapeutic Medicine. 2017, 13(6): 3003-3008.
11.Junwei Fang, Wenyu Wang, Shujun Sun, Yang Wang, Qianhua Li, Mingfeng Qiu* Yongyu Zhang*. Metabolomics study of renal fibrosis and intervention effect of total aglycone extracts of Scutellaria baicalensis in unilateral ureteral obstruction rats. Journal of Ethnopharmacology. 2016,192:20-29.
12.Ge Ru，Limei Han，Jin Qing，Jianyong Sheng，Ruixiang Li, Mingfeng Qiu*, & Jianxin Wang*. Effects of borneol on the pharmacokinetics of 9-nitrocamptothecin encapsulated in PLGA nanoparticles with different size via oral administration. Drug Delivery.2016,23(9):3417-3423.
13.Song Xue, Ran Zhang, Jing Su, Xuelan Li,Mingfeng Qiu*, Yingzi Wang*. 27 Fingerprint analysis of Clerodendranthus Spicatus from different regions by high-performance liquid chromatography. Asian Journal of Traditional Medicines，2016,11(1):1-10.
14.Linjing Zhao, Aihua Zhao, Tianlu Chen, Wenlian Chen, Jiajian Liu, Runmin Wei, Jing Su, Xuelan Tang, Keyi Liu, Ran Zhang, Guoxiang Xie, Jun Panee, Mingfeng Qiu*, Jia Wei*. Global and Targeted Metabolomics Evidences of the Protective Effect of Chinese Patent Medicine Jinkui Shenqi Pill on Adrenal Insufficiency after Acute Glucocorticoid Withdrawal in Rats. Journal of Proteome Research. 2016,15(7):2327-2336 .
15.Feng Zheng, Biao Zhang, Yanan Sun, Mingfeng Qiu*, Jing Su. Evaluation of WO A1, FKBP52-Tau Interaction as novel therapeutical target for treating the neurological disorders involving Tau dysfunction. Expert Opinion on Therapeutic Patents, 2015,25(7):831-835.
16. Haimiao Zou, Biao Zhang, Xinchun Xu, Jing Su, Yanan Sun, Song Xue, Xiaoyan Wang, Mingfeng Qiu*. Urinary metabolomic Strategy to evaluate Compound Danshen Dripping Pills for myocardial ischaemia in rats. Journal of Pharmaceutical and Biomedical Analysis, 2015, 112: 98-105.
17.Qing Lin, Yunpeng Cai, Mingfeng Qiu*, Jing Su*, and Weien Yuan. Development 5-fluorouracil-loaded PLGA microspheres using a solid-in-oil-in-hydrophilic oil （S/O/Oh）novel method for treatment of tumor, Oncology Reports. 2014,32(6):2405-2410.
18.Linjing Zhao, Hongbing Wu, Aihua Zhao, Huili Lu, Wei Sun, Chungwah Ma, Yiting Yang, Xue Xin, Haimiao Zou, Mingfeng Qiu*, Wei Jia*. The in vivo and in vitro study of polysaccharides from a two-herb formula on ulcerative colitis and potential mechanism of action. Journal of Ethnopharmacology, 2014,153,(1): 151-159.
19.Hong-Mei An, Guo-Wen Li, Chen Lin, Chao Gu, Miao Jin, Wen-Xian Sun, Ming- Feng Qiu*, Bing Hu. Acorus Tatarinowii Schott extract protects PC12 cells from Amyloid-β induced neurotoxicity. Pharmazie, 2014, 69(5): 391-395.
20.Xue Xin, Haimiao Zou, Ningning Zheng, Xinchun Xu,Yinmin Liu, Xiaoxian Wang, Hongbing Wu, Lina Lu，Jing Su, Mingfeng Qiu*, Xiaoyan Wang. Metabonomic strategy to study the evaluation of Chinese Medicine Compound Danshen Dripping Pills interfering myocardial ischemia in rats. Evidence-Based Complementary and Alternative Medicine. 2013, 2013:1-10.
21.Linjing Zhao1, Hongbing Wu1, Mingfeng Qiu1, Wei Sun, Runmin Wei, Xiaojiao Zheng, Yiting Yang, Xue Xin, Haimiao Zou, Tianlu Chen, Jiajian Liu, Lina Lu, Jing Su, Chungwah Ma, Aihua Zhao, Wei Jia. Metabolic Metabolic Signature of the Kidney Yang Deficiency Syndrome and Protective Effects of Two Herb Extracts in Rats GC/TOF MS. Evidence-Based Complementary and Alternative Medicine. 2013, 2013:1-10.
22.Zheng Ningning, Dai Jianye, Cao Huijuan, Sun Shujun, Fang Junwei, Li Qianhua, Su Shibing, Zhang Yongyu, Qiu Mingfeng*, Huang Shuang. Current Understanding on Antihepatocarcinoma Effects of Xiao Chai Hu Tang and Its Constituents. Evidence-Based Complementary and Alternative Medicine, 2013,2013:1-14.
23.Rui Liu, Zheng Zhang, Huan Liu, Panpan Hou, Jun Lang, Sheng Wang, Hongli Yan, Pengcheng Li, Zhigang Huang, Hongbing Wu, Mingqiang Rong, Jian Huang, Hong Wang, Longbao Lv, Mingfeng Qiu, Jiuping Ding,Ren Lai*. Human β-Defensin 2 Is a Novel Opener of Ca2+-Activated Potassium Channels and Induces Vasodilation and Hypotension in Monkeys. HYPERTENSION, 2013,62(2): 415-425.
24.Guoxiang Xie, Aihua Zhao, Tianlu Chen, Huiyuan Chen, Xin Qi, Xiaojiao Zheng, Yan Ni, Yu Cheng, Ke Lan, Chun Yao, Mingfeng Qiu, and Wei Jia*. Metabolic Fate of Tea Polyphenols in Humans. J. Proteome Res. 2012,11(6):3449-3457 .
25.Hongbing Wu, Jianxu, Li, Qizhi Zhang, Xiluan Yan, Liangran Guo, Xiaoling Gao, Mingfeng Qiu, Xinguo Jiang, Ren Lai, Hongzhuan Chen. A novel small Odorranalectin-bearing cubosomes:Preparation, brain delivery and pharmacodynamic study on amyloid-β25–35-treated rats following intranasal administration. European Journal of Pharmaceutics and Biopharmaceutics, 2012,80(2): 368-378.
26.Zhiyong Guo, Aihua Zhao*, Tianlu Chen, Guoxiang Xie,Mingmei Zhou, Mingfeng Qiu, Wei Jia. Differentiation of Schisandra chinensis and Schisandra sphenanthera using metabolite profiles based on UPLC-MS and GC-MS. Natural product research, 2012, 26(3): 255-263.
27.Tie Zhao, Mingfeng Qiu*, Guoxiang Xie, Hongbing Wu, Wei Jia. Gender differences in the bioavailablility and pharmacokinetics of γ-schisndrin from a Wurenchun-PVP k30 solid dispersion in rats. Asian Journal of Traditional Medicines, 2010, 5(6): 51-59.
28.Guoxiang Xie, Mao Ye, Yungang Wang, Yan Ni, Mingming Su, Hua Huang, Mingfeng Qiu*, Aihua Zhao, Xiaojiao Zheng, Tianlu Chen, Deborah E. Kipp, and Wei Jia*. Characterization of Pu-erh Tea using Chemical and Metabolic Profiling Approaches. J Agric Food Chem. 2009, 57(8): 3046-3054 .
29.Guoxiang Xie, Robert Plumb, Mingming Su, Zhaohui Xu, Aihua Zhao, Mingfeng Qiu, Xiangbao Long, Zhong Liu, Wei Jia. Ultra-performance LC/TOF MS analysis of medicinal Panax herbs for metabolomic research, Journal of Separation Science, 2008, 31(6-7), 1015–1026.
30.Houkai Li, Yan Ni, Mingming Su, Yunping Qiu, Mingmei Zhou, Mingfeng Qiu, Aihua Zhao, Liping Zhao, Wei Jia*, Pharmaco-metabonomic phenotying reveals different responses to xenobiotic intervention in rats, Journal of Proteome Research, 2007, 6(4):1364-1370 .
31.Xiangping Chu, Zhaohui Xu, Dazheng Wu, Aihua Zhao, Mingmei Zhou, Mingfeng Qiu, Wei Jia*. In vitro and in vivo evaluation of the anti-asthmatic activities of fractions from Pheretima. Journal of Ethnopharmacology, 2007,111(3):490-495.
32.Guoxiang Xie, Yunping Qiu, Mingfeng Qiu, Xianfu Gao, Wei Jia, Analysis of dencichine in Panax notoginseng by gas chromatography-mass spectrometry with ethyl chloroformate derivatization, Journal of Pharmaceutical and Biomedical Analysis, 43(3):920-925, 2007.
33.Guoxiang Xie, Mingfeng Qiu, Aihua Zhao, Peng Li, Gu Xue, Wei Jia*.Determination of endogenous metabolites in obesity rat urine by pressurized capillary electrochromatography with ethyl chloroformate derivatization. Chinese Journal of Analytical Chemistry. 2007,35(8):1111-1115.
34.Guoxiang Xie, Mingfeng Qiu, Xianfu Gao, Wei Jia, Fingerprint Analysis of Flos Carthami by Pressurized CEC and LC, Chromatographia,2006.64(11/12):739-743.
35.Yongyu Zhang, Xiaoyan Wang，Xiaorong Wang, Zhaohui Xu, Zhe Liu， Qian Ni, Xiangping Chu, Mingfeng Qiu, Aihua Zhao, Wei Jia. Protective effect of flavonoids from Scutellaria baicalensis Georgi on cerebral ischemia injury. Journal of Ethnopharmacology, 2006.108(3):355-360.
36.Wei Jia, Xiaorong Wang, Desheng Xu, Mingfeng Qiu and Yongyu Zhang, Common traditional Chinese medicinal herbs for dysmenorrhea, Phytotherapy Research, 2006,20(10):819-824.
37.Ming-feng Qiu, Wei Jia, Shaoshun Li, Zhaohui Xu, Xia Sun, Xiaorong Wang, Yongyu Zhang, Guoxiang Xie. A New Silymarin Preparation Using Solid Dispersion Technique, Advances in Therapy, 2005,22 (6): 595-600.
38.Xianfu Gao, Chunbao Zhu, Wei Jia*, Wenyuan Gao, Mingfeng Qiu, Yongyu Zhang, Peigen Xiao. Induction and characterization of adventitious roots directly from the explants of Panax notoginseng, Biotechnology Letters. 2005,27(22): 1771–1775.
39.Shen Qi, Sun Xia, Qiu Mingfeng, Jia Wei, Xu Lianying. Effect of Anisaldehyde, Anethole and Cinnamaldehyde on the in vitro percutaneous absorption of 5-fluorouracil, Chinese Journal of Natural Medicines, 3(2):101-105, 2005.
40.Wei Jia, Mingfeng Qiu, Xia Sun, Yunping Qiu, Mingming Su. Preparation of Indapamide Slow-Release Pellets, Advances in Therapy, 2004,21(4):238-246.


主持课题20项、参加科研项目21项（含国家自然科学基金4项、国家九五攻关、国际合作项目等），在EJPS、JEP、JPBA、ECAM、JAFC、JPR、《中国中药杂志》、《中草药》、《中成药》等杂志上发表论文126篇（含SCI 40篇，高被引论文1篇，单篇被引过百次1篇），编写著作教材11部（含教材3部、主编1部、副主编5部），申请专利32项（授权9项）。科研获奖6项，包括中华中医药学会科技二等奖、市政府决策咨询成果二等奖等。