摘要/Abstract

近年来过渡金属与以苯并四咪唑类化合物为代表的手性路易斯碱协同作用下的不对称催化反应取得了重要的进展，包括芳基醋酸酯α衍生化及乙内酰脲、二氢喹啉酮等结构的合成、双手性中心烯丙基化反应和α-氨基酸衍生物合成等.这些反应在有机合成中有广阔的应用前景.本文将对这类反应的研究进展做简要的介绍.
关键词: 路易斯碱催化, 过渡金属催化, 协同催化, α-位官能团化, 烯丙基化反应
Recent developments in the field of asymmetric α-functionalization of arylacetic acids and derivatives by combining chiral Lewis base and transition-metal catalyst are summarized. The unique character of Lewis bases, specifically, chiral benzotetramisole derivatives, plays a crucial role in these innovative strategies.
Key words: Lewis base catalyst, transition metal catalyst, cooperative catalysis, α-functionalization, allylation reaction


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