摘要/Abstract

研究了5,10,15-三(五氟苯基)咔咯铜配合物(CuTPFC)催化的烯丙基sp³杂化C—H键与羧酸的氧化交叉脱氢偶联反应(CDC). 该反应可以平稳地生成烯丙基酯, 且具有广泛的底物范围和良好的官能团耐受性. 克级实验中, 在催化剂的用量仅为0.01 mol%的情况下, 转换量(TON)可以达到5100, 表明目前的催化体系在烯丙基酯合成方面具有潜在的应用前景.
关键词: 铜, 咔咯, 交叉脱氢偶联, 烯丙基化合物, 催化
Copper 5,10,15-tris(pentafluorophenyl)corrole (CuTPFC) catalyzed oxidative cross dehydrogenative coupling (CDC) of allylic sp³-C—H bonds and acids had been investigated in a homogeneous system, which provided allylic esters smoothly. This reaction proceeded with broad substrate scope and good functional group tolerance. In a gram scale test, the turnover number (TON) reached 5100 at only 0.01 mol% catalyst loading, indicating the current catalytic system has potential uses in the allylic esters.
Key words: copper, corrole, cross dehydrogenative coupling, allylic compounds, catalysis


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