摘要/Abstract

基于噁唑啉酰胺导向基团实现了铜参与的烯基酰胺b-碳氢键与端炔的炔基化反应，构建了一系列1，3-共轭烯炔化合物.该反应条件温和，底物适用范围广，具有良好的区域及立体选择性.
关键词: b-碳氢键炔基化, 铜, 1,3-烯炔, 立体选择性
Cu(Ⅱ)-mediated b-C-H alkynylation of acrylamides with terminal alkynes is described by employing amide-oxazoline bidentate auxiliary, forming the conjugated 1,3-enynes. This protocol is characterized by its mild conditions, broad substarate scope and excellent regio- and stereo-selectivity.
Key words: b-C-H alkynylation, copper, 1,3-enynes, stereo-selectivity


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