摘要/Abstract

固定二氧化碳（CO₂）的工业过程远远落后于人类活动产生的碳排放量.由于二氧化碳是一种丰富、无毒且廉价易得的碳资源，因此开发出将二氧化碳转化为有价值的产品，以实现可持续发展的化学合成是非常有意义的.基于过渡金属催化和有机催化活化CO₂的机理研究，近年来已开发出多种有效的CO₂的不对称化学固定方法.讨论了通过CO₂的不对称化学固定实现的小分子化合物的手性合成的进展.通过阐述催化剂、CO₂和底物之间的相互作用，旨在激发CO₂不对称转化的新型催化系统的设计.
关键词: 二氧化碳, 不对称催化, 对映选择性, 羧基化, 环化反应
Industrial processes of fixing carbon dioxide (CO₂) lag far behind the carbon emission generated by human activity. Since CO₂ is an abundant, non-toxic, and cost-effective one carbon source, it is highly desirable to develop methodologies on converting CO₂ into valuable products for sustainable purpose. Based on the mechanistic insight of CO₂ activation by transition-metal catalyst and organocatalyst, a variety of efficient asymmetric CO₂ chemical fixation processes have been developed in recent years. This review discusses the advances of enantioselective synthesis of small molecules by asymmetric catalytic reactions with CO₂. The interaction between catalyst, CO₂ and substrate has been elaborated aiming to inspire the design of new catalytic systems for asymmetric CO₂ transformation.
Key words: carbon dioxide, asymmetric catalysis, enantioselectivity, carboxylation, cyclization


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