摘要/Abstract

γ-戊内酯（GVL）是重要的生物质平台分子，将其转化为高附加值的化学品和燃料，具有重要的应用前景.介绍了一种在温和条件下通过还原胺化/环化反应，分别使用锆基路易斯酸催化剂Zr-P-O和ZrOCl₂·8H₂O，催化GVL与胺类化合物合成羟基酰胺类化合物和吡咯烷酮类化合物.特别值得一提的是，在无溶剂的情况下，均可以得到中等偏上的产物收率.该方法为GVL的应用研究进一步奠定了基础.
关键词: γ-戊内酯, 羟基酰胺, 吡咯烷酮, 路易斯酸催化, 锆基催化剂
γ-Valerolactone (GVL) is an important biomass platform molecule, it can be converted into high value-added chemicals and fuel, which has important application prospects. This article describes a method for the synthesis of hydroxyamides and pyrrolidones from GVL and amine compounds by reductive amination/cyclization reactions under mild conditions using zirconium-based Lewis acid catalysts Zr-P-O and ZrOCl₂·8H₂O, respectively. In particular, a moderately high product yield can be obtained with the absence of a solvent. This method further lays the foundation for the application research of GVL.
Key words: γ-valerolactone, hydroxyamide, pyrrolidone, Lewis acid catalysis, zirconium-based catalyst


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