摘要/Abstract

制备了一种以三苯胺、辛基芴和丙二腈分别作为给体、π桥和受体基团的扭转型D-π-A结构的用于检测Fe³⁺离子的纳米颗粒（TA-DF-BDM/PSMA NPs）荧光探针.TA-DF-BDM/PSMA NPs具有610 nm红光发射，并具有大的斯托克斯位移（203 nm左右）.TA-DF-BDM/PSMA NPs可在纯水中检测Fe³⁺，并具有较高的选择性和灵敏度以及低的检出限（0.9883 μmol/L）.更重要的是TA-DF-BDM/PSMA NPs具有稳定的光物理性质，并且具有可逆性、较好的生物相容性和较低的细胞毒性，使其可应用于生物成像研究.
关键词: 荧光探针, Fe^3＋离子, 亲水性, 可逆性
In this work, the novel fluorescent probes for detecting Fe³⁺ ions based on nanoparticles (TA-DF-BDM/PSMA NPs) of fluorescence material with twisting D-π-A configuration was designed and prepared, in which triphenylamine (TA), 9,9-dioctylfluorene (DF) and benzylidenemalononitrile (BDM) serve as electron donor (D) unit, π conjugated unit, and electron acceptor (A) unit, respectively. TA-DF-BDM/PSMA NPs exhibit red-emission peak located at 610 nm in photoluminescence spectrum and larger stokes shifts (ca. 203 nm). And, TA-DF-BDM/PSMA NPs exhibit high selectivity for detecting Fe³⁺ ions in pure water with high sensitivity and low detection limit of 0.9833 μmol/L. More importantly, TA-DF-BDM/PSMA NPs show such properties as good photophysical stability, reversibility, excellent biocompatibility and low cytotoxicity, which can be utilized in bioimaging investigations.
Key words: fluorescent probes, Fe³⁺ ions, hydrophilcity, reversibility


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