摘要/Abstract

次氯酸（HClO）和次氯酸钠（NaClO）广泛存在于生命体和环境中，并与生命体的健康或疾病密切相关.近年来，为揭示HClO对生物体的作用及作用机制，已经设计出许多HClO比色荧光探针，这些次氯酸比色荧光探针由于具有灵敏、快速、高选择性、可视化和实时监测等优点而被用于环境或生物体中HClO或ClO^-的检测.根据探针对HClO识别机制的不同，将HClO比色荧光探针分为五大类，总结评价近五年来次氯酸比色荧光探针的设计、特征及实际应用.
关键词: 次氯酸, 荧光比色探针, 识别机制, 应用
Hypochlorous acid (HClO) and sodium hypochlorite (NaClO) exist widely in living organisms and environment and is closely related to the health or disease of living organisms. In recent years, in order to reveal the effect and mechanism of HClO on living organisms, many HClO colorimetric and fluorimetric probes have been designed and applied to the detection HClO or ClO^- in environment or living organisms due to their sensitivity, rapidity, high selectivity and real-time monitoring. According to the different recognition mechanism of probes for HClO, HCO colorimetric fluorescent probes are divided into five categories. The design, characteristics and practical application of hypochlorite colorimetric fluorescent probes in the past five years are summarized and evaluated.
Key words: hypochlorous acid, colorimetric and fluorimetric probe, recognition mechanism, application


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