摘要/Abstract
报道了一种铜催化N-芳基甘氨酸酯与烯醇硅醚交叉氧化偶联反应合成β-酰基-α-氨基酸酯的新方法.该反应的特点在于：反应产率较高，反应条件温和（如室温环境和廉价的催化剂等），以及可以在含水介质中顺利进行.
关键词: 铜催化, 偶联反应, 氨基酸衍生物, 合成
A novel copper-catalyzed oxidative cross-coupling reaction between N-arylglycine esters and Silyl enol ethers for the synthesis of β-acyl-α-amino acid esters has been developed. The features of this reaction are high reaction yields, mild reaction conditions (such as room temperature environments and inexpensive catalysts, etc.) and smooth operation in aqueous medium.
Key words: copper-catalyzed, coupling reactions, amino acid derivatives, synthesis
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