摘要/Abstract

亲电试剂的还原偶联反应避免了有机金属试剂的制备与使用，对各类官能团拥有极好的兼容性，为C-C键的构筑提供了一类重要的方法.近些年来，该反应的研究取得了突破性进展，实现了一系列C（sp²）-X与C（sp³）-X亲电试剂参与的交叉偶联反应.主要针对镍催化亲电试剂交叉偶联反应构筑C（sp²）-C（sp²）和C（sp²）-C（sp³）键的研究展开综述，详细介绍了各种偶联反应及其反应机制.
关键词: 偶联反应, 还原偶联, 亲电试剂, Ni催化
The cross-coupling of two electrophiles has emerged as an important and attractive method for carbon-carbon bond formation. This synthetic protocol avoids preparation of organometallic nucleophilic reagents and exhibits excellent functional group tolerance. Recently, breakthrough progress has been developed to the cross-electrophile coupling of C(sp²)-X/C(sp³)-X. The recent progress in the research of Ni-catalyzed electrophilic coupling for the construction of C(sp²)-C(sp²) and C(sp²)-C(sp³) is reviewed.
Key words: cross-coupling reaction, reductive coupling, electrophiles, Ni catalysis


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