摘要/Abstract
阿片类药物广泛用于临床，但存在呼吸抑制、成瘾性等诸多副作用，因此阿片类药物研发一直受到广泛关注.近年来相关基础研究的进展为新机制阿片类药物研究提供了重要线索.对小分子阿片类药物的近期研究热点进行了总结.
关键词: 阿片药物, 阿片受体, 阿片样副作用, 药物研究
Opioid drugs are widely used in clinical practice, but they are also notorious for their respiratory depression and addictive side effects. Therefore, tremendous efforts have been paid to the research and development of opioid drugs. Recent progresses in related research fields provide important clues for developing opioid drugs with novel mechanisms. Recent reports on several topics in the study of small molecule opioid drugs are summarized.
Key words: opioid drug, opioid receptor, opioid side effects, drug research
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