摘要/Abstract

由于吖啶特殊的结构、功能单元和在诸多领域的重要应用，对吖啶的研究在国内外重新成为热点.大的共轭环使其在荧光方面有着标记和成像等作用，而作为能够嵌入到DNA链中的化合物在医药等领域有着广泛的应用，在染料方面与天然产物的色价非常相似，此外作为光电材料化合物在有机半导体材料中代替金属半导体材料也展现出很好的潜在价值.近年来出现了微波辅助、无金属催化、一锅法合成等多种绿色、简便的合成方法和有机半导体材料等新的研发领域，为吖啶的合成和应用方面带来了更多的关注.介绍了2010年以来吖啶衍生物的各类合成方法及在医药、荧光材料、工业染料以及电致发光等诸多领域中的应用，并介绍了本课题组在吖啶研究方面的工作以及合成吖啶衍生物的新进展，最后对吖啶衍生物的合成与应用前景进行了展望.
关键词: 吖啶衍生物, 合成方法, 三组分一锅法, 微波
Due to the special functional structural units and important applications in many fields, the study of acridine derivatives has become a hot topic worldwide. The large conjugated ring enables these dyes to be markers for fluorescence and imaging. Thanks to the ability of embedding into DNA chain, they have a wide range of applications in medicine and other fields. These dyes have the very similar color index value to that of the natural compounds. As an alternative to metal semiconductor material, acridines have presented potential value in the field of organic semiconductor materials. In recent years, emerging of the new and simple preparation technique, such as microwave assisted synthesis, metal free catalysis, one pot synthesis, and so on, has brought more attention to the synthesis and application of acridines. In this paper, various synthetic methods of acridine derivatives since 2010 and their applications in medicine, fluorescent materials, industrial dyeing materials and electroluminescence are introduced. The work about acridines accomplished in our group is also introduced. In the end, the future prospective of synthesis and application of acridine derivatives is proposed.
Key words: acridine derivative, synthetic method, three-component one-pot method, microwave


PDF全文下载地址:

点我下载PDF