摘要/Abstract

探索了一种超声促进合成2-磺酰基氮杂环化合物的反应.以氮杂环氮氧化物和亚磺酸为原料，以三吡咯烷基溴化鏻六氟磷酸盐（PyBroP）为催化剂，室温下超声反应1.0 h，能够以良好的收率得到2-磺酰基氮杂环化合物.该反应具有底物适用性好，反应时间短，反应产率高等优点，为高效合成2-磺酰基氮杂环化合物及其衍生物提供了一种新的途径.
关键词: 2-磺酰基氮杂环, 氮杂环氮氧化物, 亚磺酸, 超声促进
A facile and convenient ultrasonic-assisted method for the synthesis of 2-sulfonyl nitrogen heterocyclics has been developed. Using bromo-tris-pyrrolidino-phosphonium hexafluorophosphate (PyBroP) as catalyst, the reactions were carried out under ultrasound irradiation condition at room temperature for 1.0 h, and the 2-sulfonyl nitrogen heterocyclics were obtained in good yields with nitrogen heterocyclic N-oxides and sulfinic acid as raw materials. The reaction has the advantages of good substrate suitability, short reaction times and high yields, which provides a efficient approach for the synthesis of 2-sulfonyl nitrogen heterocyclics and their derivatives.
Key words: 2-sulfonyl nitrogen heterocyclics, nitrogen heterocyclic N-oxides, sulfinic acids, ultrasound-assisted


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