xm:陈浩
xb:男
zc:研究员
xl:博士
dh:
cz:
dzyj:haoc@simm.ac.cn
grzy:https://www.researchgate.net/profile/Hao_Chen196
zjlb:研究员
zw:课题组长
txdz:上海浦东张江祖冲之路555号3-420
grjj:陈浩,研究员,课题组长。2015年获得博士学位。博士毕业后,在美国斯坦福大学分子影像中心从事NIR-II荧光,PET-CT诊疗药物研发。设计合成首个可修饰短波近红外染料CH1055 (NIR-II or SWIR, 1000 nm-1700 nm),并开发其生物医学应用。2019年2月加入上海药物研究所,担任课题组长,主要从事荧光手术导航,光热,光动力,PET-CT/SPECT-CT诊疗药物研发。以及分子影像技术在药物开发,靶标发现,药效评价,大分子药物药代动力学中的应用研究。具备化学,生物,仪器设备交叉学科研究背景,擅长使用多学科技术解决药物开发中遇到的困难。2012年至今,共发表学术论文20余篇,包括Nature Materials, Nature Communications, Chemical science等多篇一区论文。
yjfx:1. 诊疗药物研发 (荧光手术导航,光热,光动力,PET-CT/SPECT-CT等)
2. 分子影像技术在药物开发中的应用研究,包括靶标发现,药效评价,大分子药物药代动力学,“0期临床研究”(phase 0 clinical trails)等
3. 放射性药物化学(18F, 68Ga, 89Zr, 3H, 14C 等)
4. 新型成像系统的开发
dblz: 2019. 2-至今1. H. Chen, J. Wang, X. Feng, H, M. Zhu, S. Hoffmann, A. Hsu, K. Qian, D. Huang, F. Zhao, W. Liu, H. Zhang*, Z. Cheng*. Mitochondria-targeted fluorescent molecules for high efficiency cancer growth inhibition and imaging. Chemical Science, 2019, 10, 7946-79512. Y. Yang, X. Fan, L. Li, Y. Yang, A. Nuernisha, D. Xue, C. He, J. Qian*, Q. Hu*, H. Chen*, J. Liu*, W. Huang. Semiconducting Polymer Nanoparticles as Theranostic System for Near-Infrared-II Fluorescence Imaging and Photothermal Therapy under Safe Laser Fluence. ACS Nano, 2020, 14 (2), 2509–2521.2015. 6-2019. 21. A. Antaris, H. Chen, K. Cheng, Y. Sun, G. Hong, C. Qu, S. Diao, Z. Deng, X. Hu, B. Zhang, X. Zhang, O. K. Yaghi, Z. Alamparambil, X. Hong*, Z. Cheng*, H. Dai*. A Small Molecule Dye for NIR II Imaging, Nature Materials, 2015, 15, 235–242. (Co-first author)2. A. Antaris, H. Chen, S. Diao, Z. Ma, S. Zhu, C. Leila, W. Joy, L. Alexander, K. Cheng, X. Hong*, H. Dai*, Z. Cheng*. A high quantum yield moleculeprotein complex fluorophore for near-infrared II imaging. Nature Communications, 2016, 8, 15269. (Co-first author)3. K. Cheng, H. Chen, C. H. Jenkins, G. Zhang, W. Zhao, Z. Zhang, F. Han, J. Fung, M. Yang, Y. Jiang, L. Xing*, Z. Cheng*. Synthesis, Characterization, and Biomedical Applications of a Targeted Dual-Modal Near-Infrared-II Fluorescence and Photoacoustic Imaging Nanoprobe. ACS nano, 2017, 11(12), 12276-12291. (Co-first author)4. K. Shou, Y. Tang, H. Chen, S. Chen, L. Zhang, A. Zhang, Q. Fan, A*. Yu, Z*. Cheng*. Diketopyrrolopyrrole-based semiconducting polymer nanoparticles for in vivo second near-infrared window imaging and image-guided tumor surgery. Chemical Science, 2018, 9, 3105-3110. (Co-first author)
jyjl:武汉大学,药学,理学学士
删除或更新信息,请邮件至freekaoyan#163.com(#换成@)