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上海中医药大学中药学院导师教师师资介绍简介-冯年平教授
本站小编 Free考研考试/2021-01-23
个人简介:
冯年平,二级教授,博士生导师。上海市“曙光****”,教育部新世纪优秀人才,上海市优秀学科带头人。现任药剂教研室主任、国家中医药管理局中药制剂三级实验室主任。
1997年6月于中国药科大学获得博士学位后留校,1998年10月至今在上海中医药大学工作,2012年9月至2013年9月美国普渡大学高级研究****。
承担完成国家自然科学基金项目、国家重大新药创制专项、教育部博士点、上海市中药现代化专项、上海市纳米科技专项等各级课题多项,在国内外学术期刊发表论文200余篇,授权发明专利10余项,其中PCT专利1项,主编《中药药剂学》等教材和学术著作多部。曾获霍英东基金会全国高校青年教师奖、中华医学科技奖、上海市科技进步奖、中华中医药学会科学技术奖、上海市浦东新区科技创新成就奖、明治生命科学奖等。
承担课程:
承担《中药药剂学》(本科)、《药物新剂型与新技术》(研究生)等课程的教学工作。
研究领域:
新型给药系统;中药纳米技术;中药制剂的体内过程;经皮给药与功效性化妆品
电子信箱:npfeng@shutcm.edu.cn
主要学术职务
世界中医药学会联合会经皮给药专业委员会 副会长
中国中药协会科技交流与合作专业委员会 副主任委员
中国中医药信息研究会中药外治分会 副会长
中华中医药学会制剂分会副秘书长
上海市药理学会皮肤药理专业委员会 副主任委员
中国中药协会儿童健康与药物研究专业委员会 常务委员
上海市药学会药剂学专业委员会 委员
Asian Journal of Pharmaceutical Sciences(SCI)编委
CurrentDrug Delivery (SCI) 编委
Evidence-Based Complementary and Alternative Medicine (SCI) 编委
主要教材与著作
中药药剂学,主编,科学出版社,2017
中药药剂学实验【双语版】,共同主编,科学出版社,2018
中药经皮给药与功效性化妆品,共同主编,中国医药科技出版社,2019
现代中药制剂设计,共同主编,中国医药科技出版社,2020
中成药学,副主编,上海科学技术出版社 2009
物理药剂学,副主编,中国中医药出版社,2018
药剂学,副主编,中国中医药出版社,2020
中药提取分离技术原理与应用,共同主编,中国医药科技出版社 2005
主要论文(通讯作者):
[1] Yuanzhi He, Xuefeng Hou, Jingwen Guo, Zehui He, Teng Guo, Ying Liu, Yongtai Zhang, Jiwen Zhang, Nianping Feng?. Activation of a gamma–cyclodextrin–based metal–organic framework using supercritical carbon dioxide for high–efficient delivery of honokiol. Carbohydrate Polymers, 2020,235:115935
[2] Ying Liu?, Xingmei Xie?, Xuefeng Hou, Junyi Shen, Jiangpei Shi, Haizhen Chen, Yuanzhi He, Zhi Wang, Nianping Feng?. Functional Oral Nanoparticles for Delivering Silibinin and Cryptotanshinone against Breast Cancer Lung Metastasis. Journal of Nanobiotechnology. 2020,18:83
[3] Yongtai Zhang?, Hongyu Zhang?, Kai Zhang, Zhe Li, Teng Guo, Tong Wu, Xuefeng Hou,Nianping Feng?. Co-hybridized composite nanovesicles for enhanced transdermal eugenol and cinnamaldehyde delivery and their potential efficacy in ulcerative colitis. Nanomedicine: Nanotechnology, Biology, and Medicine.2020, 28:102212
[4] Sirui Xiao?, Yulu Yan?, Jihui Zhao?, Yongtai Zhang, Nnianping Feng?. Increased microneedle-mediated transdermal delivery of tetramethylpyrazine to the brain, combined with borneol and iontophoresis, for MCAO prevention.International Journal of Pharmaceutics, 2020,575:118962
[5] Qiang Zhao, Feng Xing, Yanyan Tao, Hongliang Liu, Kai Huang, Yuan Peng, Nianping Feng?, Chenghai Liu?. Xiaozhang Tie improves intestinal motility in rats with cirrhotic ascites via regulating SCF/c-kit pathway in ICCs. Frontiers in Pharmacology, 2020, 11:1-10
[6] Zehui He, Yongtai Zhang and Nianping Feng?. Cell membrane-coated nanosized active targeted drug delivery systems homing to tumor cells: A review. Materials Science & Engineering C. 2020,106:110298
[7] Teng Guo?, Ning Cheng?, Jihui Zhao, Xuefeng Hou, Nianping Feng?. Novel nanostructured lipid carriers-loaded dissolving microneedles for controlled local administration of aconitine. International Journal of Pharmaceutics2019, 572:118741
[8] Yuanzhi He, Xuefeng Hou, Ying Liu and Nianping Feng?. Recent progress in synthesis, structural diversity and emerging applications of cyclodextrin-based carbohydrate metal-organic frameworks. Journal of Materials Chemistry B2019,7:5602-5619
[9] Xuefeng Hou, Beilei Cao, Yuanzhi He, Teng Guo, Zhe Li, Ying Liu, Yongtai Zhang, Nianping Feng?. Improved self-assembled micelles based on supercritical fluid technology as a novel oral delivery system for enhancing germacrone oral bioavailability. International Journal of Pharmaceutics 2019,569:118586
[10] Qibo Zhang?, Jihui Zhao?,Hongmei Hu, Yulu Yan, Xiaoge Hu, Kuan Zhou, Sirui Xiao, Yongtai Zhang, Nianping Feng. Construction and in vitro and in vivo evaluation of folic acid-modified nanostructured lipid carriers loaded with paclitaxel and chlorin e6. International Journal of Pharmaceutics 2019,569:118595
[11] Ying Liu?, Zifei Jiang?, Xuefeng Hou, Xingmei Xie, Jiangpei Shi, Junyi Shen, Yuanzhi He, Zhi Wang, Nianping Feng?. Functional lipid polymeric nanoparticles for oral drug delivery: rapid mucus penetration and improved cell entry and cellular transport. Nanomedicine: Nanotechnology, Biology, and Medicine.2019,21:102075
[12] Kai Zhang?, Yongtai Zhang?, Nana Li,Feng Xing, Jihui Zhao, Tao Yang,Chenghai Liu?, Nianping Feng?.An herbal-compound-based combination therapy that relieves cirrhotic ascites by affecting the L-arginine/nitric oxide pathway: a metabolomics-based systematic study. Journal of Ethnopharmacology. 2019,241:112034
[13] Xiaoge Hu?,Ning Cheng?,Jihui Zhao, Xianghua Piao, Yulu Yan, Qibo Zhang, Kuan Zhou, Yongtai Zhang, Nianping Feng?. Percutaneous absorption and brain distribution facilitation of borneol on tetramethylpyrazine in a microemulsion-based transdermal therapeutic system. Asian Journal of Pharmaceutical Sciences2019,14(3):305-312.
[14] Zhe Li, Yongtai Zhang and Nianping Feng?. Mesoporous silica nanoparticles: synthesis, classification, drug loading, pharmacokinetics, biocompatibility, and application in drug delivery. Expert Opinion on Drug Delivery.2019,16(3):219-237
[15] QingXia?,YongtaiZhang?,ZheLi,XuefengHouandNianpingFeng?. Red blood cell membrane-camouflaged nanoparticles: A novel drug delivery system for antitumor application.Acta Pharmaceutica Sinica B. 2019,9(4):675-689
[16] Yongtai Zhang?, Qing Xia?, Yanyan Li?, Zehui He?, Zhe Li, Teng Guo, Zhonghua Wu, and Nianping Feng?. CD44 assists topical anti-psoriatic efficacy of curcumin-loaded hyaluronan-modified ethosomes: a new strategy for clustering drug in inflammatory skin. Theranostics.2019;9(1):48-64
[17] Yongtai zhang, Zhi Wang; Li-Na Shen; Yan-Yan Li; Ze-Hui He; Qing Xia; Nianping Feng?. A novel microemulsion-based isotonic perfusate modulated by Ringer's solution for improved microdialysis recovery of liposoluble substances. Journal of Nanobiotechnology2018,16:91
[18] Qiangyuan Fan?, Yongtai Zhang?,Xuefeng Hou, Zhe Li, Kai Zhang, Qun Shao, Nianping Feng?. Improved oral bioavailability of notoginsenoside R1 with sodium glycocholate-mediated liposomes: preparation by supercritical fluid technology and evaluation in vitro and in vivo. International Journal of Pharmaceutics.2018,552(1-2):360-370
[19] Jun Liang?, Ying Liu?, Jinguang Liu, Zhe Li, Qiangyuan Fan, Zifei Jiang, Fei Yan, Zhi Wang, Peiwen Huang and Nianping Feng?. Chitosanfunctionalized lipidpolymer hybrid nanoparticles for oral delivery of silymarin and enhanced lipidlowering effect in NAFLD. Journal of Nanobiotechnology2018,16:64
[20]Nana Li?, Zhi Wang?, Yongtai Zhang, Kai Zhang, Jianxu Xie, Ying Liu, Wansi Li Nianping Feng?. Curcumin-loaded redox-responsive mesoporous silica nanoparticles for targeted breast cancer therapy. Artificial Cells, Nanomedicine, and Biotechnology. 2018,46(52):5921-5935
[21] Gang Yang,Zhe Li,Qun Shao,NianpingFeng?. Measurement and correlation study of silymarin solubility in supercritical carbon dioxide with and without a cosolvent using semi-empirical models and back-propagation artificial neural networks. Asian Journal of Pharmaceutical Sciences,2017, 12(5):456-463
[22] Ying Liu, Jinguang Liu, Jun Liang, Meiying Zhang, Zhe Li, Zhi Wang, Beilei Dang, Nianping Feng?. Mucosal transfer of wheat germ agglutinin modified lipid–polymer hybrid nanoparticles for oral delivery of oridonin.Nanomedicine: Nanotechnology Biology and Medicine.2017;13(7): 2219-2229
[23] Kai Zhang, Yongtai Zhang, Zhe Li, Nana Li, Nianping Feng?. Essentialoil-mediated glycerosomes increase transdermal paeoniflorin delivery: optimization, characterization, and evaluation in vitro and in vivo.International Journal of Nanomedicine.2017,12:3521-3532
[24] Zhang, M., Dai, T. & Feng, N?. A novel solubility-enhanced rubusoside-based micelles for increased cancer therapy. Nanoscale Res Lett2017,12: 274.
[25] Gang Yang,Yaping Zhao,Yongtai Zhang,Beilei Dang, Ying Liu, Nianping Feng?. Enhanced oral bioavailability of silymarin using liposomes containing a bile salt: preparation by supercritical fluid technology and evaluation in vitro and in vivo. International Journal of Nanomedicine.2015:10 6633–6644
[26] Feng Shi, Yongtai Zhang, Gang Yang, Teng Guo, Nianping Feng?. Preparation of a micro/nanotechnology based multi-unit drug delivery system for a Chinese medicine Niuhuang Xingxiao Wan and assessment of its antitumor efficacy. International Journal of Pharmaceutics. 2015, 492:244-247
[27] Teng Guo, Yongtai Zhang, Jihui Zhao, Chunyun Zhu and Nianping Feng?. Nanostructured lipid carriers for percutaneous administration of alkaloids isolated from Aconitum sinomontanum.Journal of Nanobiotechnology. 2015,13:47
[28] Ying Liu, Nian-Ping Feng?. Nanocarriers for the delivery of active ingredients and fractions extracted from natural products used in traditional Chinese medicine (TCM). Advances in Colloid and Interface Science. 2015,221: 60–76
[29] Ying Liu#, Man He#, Mengmeng Niu, Yiqing Zhao, Yuanzhang Zhu, Zhenhua Li, Nianping Feng?. Delivery of vincristine sulfate-conjugated gold nanoparticles using liposomes: a light-responsive nanocarrier with enhanced antitumor efficiency. International Journal of Nanomedicine2015:10 3081–3095
[30] Zhang Yong-Tai, Han Meng-qing, Shen Li-Na, Zhao Ji-Hui, Feng Nian-Ping?. Solid lipid nanoparticles formulated for transdermal aconitine administration and evaluated in vitro and in vivo. Journal of Biomedical Nanotechnology. 2015,11(2):351-361
[31] Feng Shi, Nianping Feng?, E. Omari-Siaw. Realgar nanoparticle-based microcapsules: preparation and in vitro/in vivo characterizations. Journal of Pharmacy and Pharmacology.2015,67(1):35-42
[32] Li-Na Shen, Yong-Tai Zhang, Qin Wang, Ling Xu, Nian-Ping Feng?. Preparation and evaluation of microemulsion-based transdermal delivery of total flavone of rhizoma arisaematis. International Journal of Nanomedicine. 2014,9(1):3453—3464
[33] Rong Tan, Mengmeng Niu, Jihui Zhao, Ying Liu, Nianping Feng?. Preparation of vincristine sulfate-loaded poly (butylcyanoacrylate) nanoparticles modified with pluronic F127 and evaluation of their lymphatic tissue targeting. Journal of Drug Targeting 2014 ;22(6):509-17.
[34] Li-Na Shen, Yong-Tai Zhang, Qin Wang, Ling Xu,Nian-Ping Feng?. Enhanced in vitroand in vivoskin deposition of apigenin delivered using ethosomes. International Journal of Pharmaceutics,2014 ,460(1-2):280-288
[35] Yi-qing Zhao Li-ping Wang, Chao Ma, Kun Zhao, Ying Liu, Nian-ping Feng?. Preparation and characterization of tetrandrine-phospholipid complex loaded lipid nanocapsules as potential oral carriers. Int J Nanomedicine.2013:8,4169-4181
[36] Shi F, Yang G ,Ren J, Du Y, Feng NP?. Formulation design,preparation, and in vitro and in vivo characterization of β-elemence-loaded nanostructured lipid carriers. Int J Nanomedicine.2013:8,2533-41
[37] Feng Shi, Ji-Hui Zhao, Ying Liu, Zhi Wang, Yong-Tai Zhang, Nian-Ping Feng?.Preparation and characterization of solid lipid nanoparticles loaded with frankincense and myrrh oil. Int J Nanomedicine. 2012,7: 2033-2043
[38] Zhi-Qiang Chen, Ying Liu, Ji-Hui Zhao, Lan Wang, Nian-Ping Feng?. Improved oral bioavailability of the poorly water-soluble drug indirubin by a supersaturatable self-microemulsifying drug delivery system. Int J Nanomedicine. 2012,7: 1115-1125
[39] Jie Xu, Ji-Hui Zhao, Ying Liu, Nian-Ping Feng?,Yong-Tai Zhang. RGD modified poly (lactic acid) nanoparticles enhances tumor targeting efficiency of oridonin.Int J Nanomedicine. 2012,7:211–219
[40] Songming Li, Ying Liu, Tao Liu, Ling Zhao, Jihui Zhao, Nianping Feng?. Development and in-vivo assessment of the bioavailability of oridonin solid dispersions by the gas anti-solvent technique.International Journal of Pharmaceutics, 2011,411:172-177
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