程志红

天然药物学, 教授, 硕士生导师


姓名
 程志红
性别
 男

职称
 教授
学历
 博士

电话
 
传真
 

电子邮件
 chengzhh@fudan.edu.cn
个人主页


通讯地址
 上海市浦东新区张衡路826号复旦大学药学院




教育经历
1998.09 – 2003.06中国药科大学中药学院，生药学博士
1994.09 – 1998.06中国药科大学中药学院，中药分析学学士

工作经历
2018.12 -- 今 复旦大学药学院，教授
2009.01 – 2018.12复旦大学药学院，副研究员
2005.10 – 2008.08美国马里兰大学(University of Maryland at College Park)，博士后
2003.07 – 2005.09中科院上海有机化学研究所，博士后

社会任职
2010.10-今 上海市药学会生药学专业委员会委员
2019.06-今 世界中医药学会联合会中药分析专业委员会理事
2015.12-今 SCI收录期刊《Current Analytical Chemistry》 编委

获奖及荣誉
2011.01 教育部自然科学二等奖-麦冬类中药的系统研究（第三完成人）

承担科研项目情况

1. 上海市科委自然科学基金面上项目: 基于微生物转化和化学修饰探讨续随子烷二萜抑制肿瘤多药耐药性的构效关系（19ZR**, 2019.7-2022.07）;
2. 国家自然科学基金面上项目: 维药天山堇菜和一枝蒿治疗重症流感的物质基础研究（**, 2015.1-2018.12）；
3. 国家自然科学基金面上项目: 基于补体抑制作用探讨紫花地丁和夏枯草的清热药效物质（**, 2011.1-2013.12）；
4. 上海市科委中药现代化专项基金: 紫花地丁清热药效物质基础及其对急性肺损伤的防治作用（09dZ**, 2009.6-2012.6）；
5. 教育部博士点基金(新教师类) : 清热药夏枯草的清热药效物质基础研究（052, 2011.1-2013.12）；
6. “国家重大新药创制” 科技重大专项课题: 中药药效物质基础及物质资源库研究关键技术（2009ZX09502-013, 2009.1-2010.12, 课题副组长）；
7. 2010国家药品标准提高研究课题：五加皮药材、五加皮饮片国家标准的制定研究（2010.9-2012.12）.

研究方向
1. 中草药的药效物质基础及质量控制研究；
2. 小分子天然产物的微生物转化研究。

代表性论著
1. Peiliang Zhang, Lei Zhang, Jiyao Shi, Na Zhang, Yue Li, Tao Wu*, Zhihong Cheng*.TLC-electrostatic field induced spray ionization-MS analysis of diverse structural skeletons and its coupling with TLC bioautography for characterization of lipase inhibitory components in American ginseng.Journal of Pharmaceutical and Biomedical Analysis, 2019, 174: 486-494;
2. Xin Liu, Chengle Yin, Yue Cao, Jinge Zhou, Tao Wu, Zhihong Cheng*. Chemical constituents fromGueldenstaedtia vernaand their anti-inflammatory activity. Natural Product Research, 2018, 32(10): 1145-1149;
3. Pei-Lan Ding, Chang-Ming He, Zhi-Hong Cheng*, Dao-Feng Chen*. Flavonoids rather than alkaloids as the diagnostic constituents to distinguish Sophorae Flavescentis Radix from Sophorae Tonkinensis Radix et Rhizoma: an HPLC fingerprint study.Chinese Journal of Natural Medicines, 2018, 16(12): 951-960;
4. Yan Qin, Boyan Gao, Haiming Shi, Jie Cao, Chengle Yin, Weiying Lu, Liangli Yu, Zhihong Cheng*. Characterization of flavonol mono-, di-, tri- and tetra-O-glycosides by ultra-performance liquid chromatography-electrospray ionization-quadrupole time-of-flight mass spectrometry and its application for identification of flavonol glycosides inViola tianschanica. Journal of Pharmaceutical and Biomedical Analysis, 2017, 142: 113-124;
5. Lei Zhang, Jiyao Shi, Jihe Tang, Zhihong Cheng*, Xiaohui Lu, Yao Kong, Tao Wu*. Direct coupling of thin-layer chromatography-bioautography with electrostatic field induced spray ionization-mass spectrometry for separation and identification of lipase inhibitors in lotus leaves. Analytica Chimica Acta, 2017, 967: 52-58;
6. Yiqing Wu, Chengle Yin, Yue Cao, Xin Liu, Jinxiang Yu, Jian Zhang, Boyang Yu, Zhihong Cheng*. Regioselective hydroxylation of lathyrane diterpenoids biocatalyzed by microorganisms and its application in integrated synthesis. Journal of Molecular Catalysis B: Enzymatic, 2016, 133: S352-S359;
7. Dongsheng Du, Yan Lu, Zhihong Cheng*, Daofeng Chen*. Structure characterization of two novel polysaccharides isolated from the spikes of Prunella vulgaris and their anticomplement activities. Journal of Ethnopharmacology, 2016, 193: 345-353;
8. Yan Qin, Yingming Pang, Zhihong Cheng*. Needle trap device as a new sampling and preconcentration approach for volatile organic compounds of herbal medicines and its application to the analysis of volatile components in Viola tianschanica. Phytochemical Analysis, 2016, 27(6):364-374;
9. Chengle Yin, Jinge Zhou, Yiqing Wu, Yue Cao, Tao Wu, Shoude Zhang, Honglin Li, Zhihong Cheng*. Pterocarpans and triterpenoids from Gueldenstaedtia verna. Fitoterapia, 2015, 106: 46-54;
10. Dongsheng Du, Zhihong Cheng*, Daofeng Chen*. Anti-complement sesquiterpenes fromViola yedoensis. Fitoterapia, 2015, 101: 73-79;
11. Jie Cao, Chengle Yin, Yan Qin, Zhihong Cheng*, Daofeng Chen. Approach to the study of flavone di-C-glycosides by high performance liquid chromatography-tandem ion trap mass spectrometry and its application to characterization of flavonoid composition in Viola yedoensis. Journal of Mass Spectrometry, 2014, 49: 1010-1024;
12. Guodong Xiao, Guowen Li, Liang Chen, Zijia Zhang, Jun-Jie Yin, Tao Wu*, Zhihong Cheng*, Xiaohui Wei, Zhengtao Wang. Isolation of antioxidants from Psoralea corylifolia fruits using high-speed counter-current chromatography guided by thin layer chromatography-antioxidant autographic assay. Journal of Chromatography A, 2010, 1217: 5470-5476;
13.Zhihong Cheng, Huiping Zhou, Marla Luther, Junjie Yin, Liangli (Lucy) Yu*. Effects of wheat antioxidants on oxygen diffusion-concentration products in liposomes and key genes for cholesterol biosynthesis and metabolism in primary rat hepatocytes. Journal of Agricultural & Food Chemistry, 2008, 56(13): 5033-5042;
14.Zhihong Cheng, Yinlong Guo*, Haoyang Wang, Guoqiang Chen. Qualitative and quantitative analysis of quaternary ammonium alkaloids from Rhizoma Corydalis by MALDI-FTMS coupled with a special precipitation reaction using Reinecke salt. Analytica Chimica Acta, 2006, 555: 269-277;
15.Zhihong Cheng, Boyang Yu*, Cordell Geoffrey A., Shengxiang Qiu*. Biotransformation of quinovic acid glycosides by microbes: direct conversion of the ursane to the oleanane triterpene skeleton by Nocardiasp. NRRL 5646. Organic Letters, 2004, 6(18): 3163-3165.