陈彦佐 副教授 硕士生导师
电话：
E-mail: chenyz@ecust.edu.cn
地址：上海市徐汇区梅陇路130号 实验18楼329室
邮编：200237

个人简介：
2013年毕业于复旦大学药学院药剂学专业，获理学博士学位。同年9月加入华东理工大学药学院，从事新型纳米递药系统方向的博士后研究。2017年至2018年间在美国北卡罗来纳大学教堂山分校Leaf Huang教授课题组进行肿瘤微环境和免疫机制方面研究。2018年9月晋升副教授，从事药剂学相关的教学和科研工作。作为项目负责人，先后主持中国博士后基金，上海市博士后基金，国家自然科学基金青年基金，教育部基本科研业务费探索研究基金等科研项目6项，发表SCI科研论文30余篇，申请中国发明专利3项，参与出版教材3册。


研究方向：

1.新型药物传递系统的构建与评价
2.肿瘤联合治疗策略研究
3.药物新剂型与新制剂的研究开发


代表性论文：
1.Yanzuo Chen, Wantong Song*, Limei Shen, Nasha Qiu, Mengying Hu, Yun Liu, Qi Liu, Leaf Huang*. Vasodilator hydralazine promotes nanoparticle penetration in advanced desmoplastic tumor.ACS Nano.2019; DOI:10.1021/acsnano.8b078302.
2. Junru Wu, Shu Feng, Wenchao Liu, Feng Gao*,Yanzuo Chen*. Targeting integrin-rich tumors with temoporfin-loaded vitamin-E-succinate-grafted chitosan oligosaccharide/d-α-tocopheryl polyethylene glycol 1000 succinate nanoparticles to enhance photodynamic therapy efficiency.Int. J. Pharm.2017; 528(1-2): 287-298.
3.Yanzuo Chen, Shu Feng, Wenchao Liu, Zeting Yuan, Peihao Yin, Feng Gao*. Vitamin E succinate-grafted-chitosan oligosaccharide/RGD-conjugated TPGS mixed micelles loaded with paclitaxel for U87MG tumor therapy.Mol. Pharm.2017; 14(4):1190-1203.
4. Yukun Huang, Wenchao Liu, Feng Gao, Xiaoling Fang,Yanzuo Chen*. c(RGDyK)-decorated Pluronic micelles for enhanced doxorubicin and paclitaxel delivery to brain glioma.Int. J. Nanomedicine.2016; 11: 1629-1641.
5.Yanzuo Chen*, Wei Zhang, Yukun Huang, Feng Gao, Xiaoling Fang*. In vivo biodistribution and anti-tumor efficacy evaluation of doxorubicin and paclitaxel-loaded Pluronic micelles decorated with c(RGDyK) peptide.PLoS One.2016; 11(3): e**.
6.Yanzuo Chen, Yukun Huang, Dongdong Qin, Wenchao Liu, Chao Song, Kaiyan Lou*, Wei Wang, Feng Gao*. β-cyclodextrin based inclusion complexation bridged biodegradable self-assembly macromolecular micelle for the delivery of paclitaxel.PLoS One.2016; 11(3): e**.
7.Yanzuo Chen*,WeiZhang,YukunHuang,FengGao,XianyiSha,XiaolingFang*. Pluronic-based functional polymeric mixed micelles for co-delivery of doxorubicin and paclitaxel to multidrug resistant tumor.Int. J. Pharm.2015; 488(1-2): 44-58.
8.Yanzuo Chen*,WeiZhang,YukunHuang,FengGao,XianyiSha,KaiyanLou,XiaolingFang*. The therapeutic effect of methotrexate-conjugated Pluronic-based polymeric micelles on the folate receptor-rich tumors treatment.Int. J. Nanomedicine.2015; 10: 4043-4057.
9.Yanzuo Chen*,WeiZhang,YukunHuang,FengGao,XiaolingFang*. Dual-functional c(RGDyK)-decorated Pluronic micelles designed for antiangiogenesis and the treatment of drug-resistant tumor.Int. J. Nanomedicine.2015; 10: 4863-4881.
10.Yanzuo Chen,YukunHuang, Yuan Chen, Yajing Ye, Kaiyan Lou, Feng Gao*. Novel nanoparticles composed of chitosan and β-cyclodextrin derivatives as potential insoluble drug carrier.Chin. Chem. Lett.2015; 26: 909-913.
11.Yanzuo Chen, Wuli Yang, Baisong Chang, Hangting Hu, Xiaoling Fang, Xianyi Sha*. In vivo distribution and antitumor activity of doxorubicin-loaded N-isopropylacrylamide-co-methacrylic acid coated mesoporous silica nanoparticles and safety evaluation.Eur. J. Pharm. Biopharm.2013; 85: 406-412.