张井岩教授，博士生导师
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电话:021-64253846
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传真:021-64253846
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E-mail:jyzhang@ecust.edu.cn
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个人简介
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张井岩，女，1968年9月生。2000年3月毕业于以色列魏兹曼科学研究院(WeizmannInstituteofScience，Israel)，获理学博士学位。2000年3月至2003年3月先后在美国明尼苏达大学（UniversityofMinnesota）化学系和生物化学系做博士后研究。2003年4月至2005年10月在美国明尼苏达大学生物化学系做研究员（ResearchAssociate)。2005年11月起任华东理工大学药学院教授。研究专长为化学生物学等。已在J.Am.Chem.Soc.,ACSNano,Chem.Commun.,Small,J.Phys.Chem.B,J.Biology.Chem.,Langumir,Biochemistry,BBRC，J.MolecularcatalysisA:Chemical等国外专业期刊发表研究论文，单篇被同行引用上百次。现主持三项国家自然基金、国家重点实验室重点项目、浦江人才计划项目以及政府间科技合作项目等科研项目。

研究方向
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生物化学：含金属酶的催化反应机理，生理活性，以及在药物合成中的应用。
生物无机化学：金属蛋白质活性中心的模拟及其生物催化反应研究。
无机药物化学：具有潜在药物活性的金属配合物的合成、药物活性以及作用机理研究。
获奖
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RobertJennessAward，2006，明尼苏达大学生物化学系。

代表性论著
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1.XuejiaoZhou,YanZhang,ChongWang,Xiaochen.Wu,Yang,BinZheng,Wu,ShouwuGuo*,JingyanZhang*,Photo-FentonReactionofGrapheneOxide:ANewStrategytoPrepareGrapheneQuantumDotsforDNACleavage,ACSNano2012,6,6592-6599.
2.BinZheng,ChongWang,CongyuWu,XuejiaoZhou,MinLin,XiaochenWu,XioazhenXin,XinChen,JingZheng,Hui,Liu,JingyanZhang*,ShouwuGuo*;NucleaseActivityandCytotoxicityEnhancementoftheDNAIntercalatorsviaGrapheneOxide，J.Phys.Chem.C2012,116,15839-15846.
3.LijunLu,YanyingSong,HuiLiu,JingyanZhang*,Synthesis,characterization,andpolyphenoloxidaseactivityofCuII,MnII,andFeIIIcomplexeswithaN2O2Ligand.J.Coord.Chem.2012,65,1278–1288.
4.Y.Zhang,J.Zhang,H.Wu,S.Guo*,J.Zhang*,GlasscarbonelectrodemodifiedwithhorseradishperoxidaseimmobilizedonpartiallyreducedgrapheneoxidefordetectingphenoliccompoundsJ.Electroanal.Chem.2012,681,49–55.

5.WanjunLan,HongliuRen,YuPang,ChusengHuang,YufangXu,RobertJ.BrookerandJingyanZhang*,AfaciletransportassayforH+coupledmembranetransportusingfluorescenceprobesAnalyticalMethods2012,4,44-46.
6.YanZhang,JingyanZhang*,XueleiHuang,XuejiaoZhou,HaixiaWu,andShouwuGuo*AssemblyofGrapheneOxide–EnzymeConjugatesthroughHydrophobicInteractionSmall，2012,8,154–159.HighlightedbyMaterialsviewshttp://www.materialsviews.com/details/news/1388257/Highly_Active_Enzymes_on_Graphene_Oxide_Surface.html?utm_source=author_alert&utm_medium=email&utm_campaign=author_email_alert
7.RongLi,JinleiTian,HuiLiu,ShipingYan，ShouwuGuo,JingyanZhang*Directevidencefortheroleofimidazoleindisproportionationofhydrogenperoxidebyamononuclearmanganesesalencomplex.TransitionMetChem2011,36,811–817.
8.YanZhang,HaixiaWu,XueleiHuang,JingyanZhang*andShouwuGuo*Effectofsubstrate(ZnO)morphologyonenzymeimmobilizationanditscatalyticactivity，NanoscaleResearchLetters2011,6,450
9.XuejiaoZhou,JialiZhang,HaixiaWu,HaijunYang,JingyanZhang*,andShouwuGuo*,ReducingGrapheneOxideviaHydroxylamine:ASimpleandEfficientRoutetoGraphene,J.Phys.Chem.C2011,115,11957–11961

10.Hongliu,Ren;Chong,Wang;Jiali,Zhang;Xuejiao,Zhou;Dafeng,Xu;Jing,Zheng;Shouwu,Guo*;Zhang,Jingyan*.DNACleavageSystemofNanosizedGrapheneOxideSheetsandCopperIons.ACSNano,2010,4,7169-7174.
11.FengZhang,BinZheng,JialiZhang,XueleiHuang,HuiLiu,ShouwuGuo,JingyanZhang,HorseradishPeroxidaseImmobilizedonGrapheneOxide:PhysicalPropertiesandApplicationsinPhenolicCompoundRemoval.J.Phys.Chem.C,2010,114,8469–8473.
12.JialiZhang,FengZhang,HaijunYang,XueleiHuang,HuiLiu,JingyanZhang,ShouwuGuo,GrapheneOxideasaMatrixforEnzymeImmobilization.Langmuir2010,26,6083–6085.
13.RongLi,FuqiangHuang,XiaojunJiang,MinyuanLiu,YanyingSong,HuiLiu,JingyanZhangCatalase-likeCatalyticReactionoftheDinuclearManganese-salenComplexJ.Coord.Chem.2010,63，1611-1618
14.GuankeZuo,XiaojunJiang,HuiLiu,JingyanZhang,ANovelUrinaryOxalateDeterminationMethodviaaCatalaseModelCompoundwithOxalateOxidase,AnalyticalMethods2010,2,254–258
15.JialiZhang,HaijunYang,GuangxiaShen,PingCheng,JingyanZhang,ShouwuGuo,ReductionofgrapheneoxideviaL-ascorbicacid，Chem.Commun.,2010,46,1112–1114
16.HuiLiu,JinleiTian,YingyingKou,JingyanZhang,LiFeng,DongdongLi,WenGu,XinLiu,DaizhengLiao,PengCheng,JoanRibasandShipingYan,Synthesis,structuresandmagneticpropertiesofpolynuclearmixed-valenceMnIIMnIIIcomplexescontaining3-(2-phenol)-5-(pyridin-2-yl)-1,2,4-triazoleligand,DaltonTrans.,2009,10511–10517
17.XiaojunJiang,HuiLiu,BingZhengandJingyanZhang,Coordinationmodesofbridgecarboxylatesindinuclearmanganesecompoundsdeterminetheircatalase-likeactivities,DaltonTrans.,2009,8714–8723.
18.JingHou,GuankeZuo,GuangxiaShen,HeGuo,HuiLiu,PingCheng,JingyanZhang,ShouwuGuoHollowSodiumTungstenBronze(Na0.15WO3)Nanospheres:Preparation,Characterization,andTheirAdsorptionProperties,NanoscaleRes.Lett.2009,4,1241–1246.
19.JingyanZhang,JohnLipscomb.MappingthebindingconformationofBcomponenttohydroxylaseinsolublemethanemonooxygenaseusingSpinLabelingEPRspectroscopy.Biochemistry2006,45，2913-2926
20.JingyanZhang,JohnLipscomb.RoleoftheC-terminalRegionoftheBComponentofMethylosinustrichosporiumOB3bMethaneMonooxygenaseintheRegulationofOxygenActivation,Biochemistry2006,45,1459-1469
21.JingyanZhang,HuiZheng,StecphenGroce,JohnLipscombBasisforspecificityinmethanemonooxygenaseandrelatednon-heme　iron-containingbiologicaloxidationcatalysts,J.Mol.Cat.A:Chemical2006，251,54-65.
22.AiminLiu,YiJin,JingyanZhang,BrainBrazeau,JohnLipscomb.Substrateradicalintermidiatesinsoluablemethanemonooxygenase.Biochem.Biophy.Res.Commun.2005,338,254-261
23.Patzlaff,J.S.;Zhang,J.;Brooker,R.J.;Barry,B.A.AnIsotope-editedFT-IRStudyofaSymporter,theLactosePermease.
Biochemistry2002,41,7366-7372,
24.Zhang,J.;Patzlaff,J;Brooker,RJ,etal.FT-IRstudyoftheisotopelabelledlactosepermeaseofE-coli
BiophysicalJournal2002,82,532A.
25.DiDonato,M.;Zhang,J.;Que,L.Jr.;andSarkar,B.ZincBindingtotheN-TerminalDomainoftheWilsonDiseaseCopper-TransportingATPase:ImplicationsforinvivoMetalIonMediatedRegulationofATPaseActivity.J.Biol.Chem.2002,277,13409.
26.Zhang,J.;Carl,P.J.;Zimmerman,H.;Goldfarb,D.InvestigationoftheformationofMCM-41byElectronSpinEchoEnvelopeModulationspectroscopy.J.Phys.Chem.B2002,106,5382.
27.Zhang,J.;Goldfarb,D.In-situinvestigationoftheFormationmechanismofmesoporousmaterialsviathedynamicsandorderingofspin-probes-pHandSi/surfactanteffect.MicroporousMesoporousMater.2001,48,143.
28.Zhang,J.;Goldfarb,D.ManganeseincorporationintotheMCM-41underacidicconditionsandstudiesbyhighfieldEPRandENDORtechniquesJ.Am.Chem.Soc.2000,122,7034..
29.Zhang,J.;Luz,Z.;Goldfarb,D.EvolutionoftherotationaldiffusionratesandorderparametersduringtheformationofMCM-41
J.Phys.Chem.B2000,104,279.