梁鑫淼
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电话:021-64251830
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传真:021-64251830
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E-mail:liangxm@dicp.ac.cn
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个人简介
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1987年从杭州大学免试进入大连化物所，攻读色谱专业硕士学位，师从卢佩章院士、张玉奎院士。两年后，又以优异成绩直接攻读博士学位，1992年12月毕业获博士学位并留所工作。历任大连化物所助理研究员、副研究员、研究员，大连化物所副所长；现任华东理工大学特聘教授，制药工程与过程化学研究中心主任，厦门大学“材料与生命过程分析科学”国家教委开放实验室学术委员会委员、中国仪器仪表学会分析仪器学会理事。
自1995年以来一直从事中药的化学物质基础研究，承担并完成了国家973项目“方剂关键科学问题的基础研究”中“方剂化学物质基础的研究”课题、中科院知识创新工程领域前沿项目“中药黄芪对白血病的基因调控研究及治疗药物的开发”。参加并完成国家自然科学基金重点项目“中药药效组分的指纹图谱分析的方法研究”；作为首席科学家承担“中科院知识创新工程”重大项目“基于现代理论和技术的复方中药系统研究”。近年来，在国内外专业杂志上已发表研究报告239篇，其中AngewChemIntEd,JAmChemSoc,AnalChem,ChemCommun,JOrgChem,EnvironSciTechnol,JChromatogr等SCI论文118篇，已培养博士33名、博士后5名、硕士9名，指导博士生27名、博士后3名、硕士生7名。


研究方向
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学科涉及制药工程、药物化学、有机化学和分析化学等，主要研究方向为：
1.中药系统分离纯化与化学表征技术研究。
2.新型分离材料和分离技术研究与开发。
3.有机合成方法学及其在药物合成中的应用。
4.制药过程化学的研究与开发。

获奖成果
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2001.12辽宁省自然科学一等奖
1993.10第七届中国图书奖
2000.4全国先进工作者称号
1999.10辽宁省科技功勋奖
1998.5辽宁青年五四奖章
1997.4全国五一劳动奖章
1997.3首届“中国科学院杰出青年”称号
1997.2“艰苦奋斗的创业者”称号
1997.3中华人民共和国国务院政府特殊津贴
1995.9中国科学院青年科学家奖二等奖

代表性论著
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代表性论著：(2005年以后)：
1.Zhang,Z.P.;Zheng,Y.J.;Chen,J.P.;Zhang,Q.;Ni,Y.W.;Liang,X.M.,FacileSynthesisofMonodisperseMagnesiumOxideMicrospheresviaSeed-InducedPrecipitationandTheirApplicationsinHigh-PerformanceLiquidChromatography.AdvancedFunctionalMaterials2007,inpress.
2.Guo,Z.M.;Lei,A.W.;Zhang,Y.P.;Xu,Q.;Xue,X.Y.;Zhang,F.F.;Liang,X.M.,“ClickSaccharides”:NovelSeparationMaterialsforHydrophilicInteractionLiquidChromatography.ChemicalCommunications2007,inpress.
3.Zhang,Z.P.;Zheng,Y.J.;Zhang,J.X.;Zhang,Q.;Chen,J.P.;Liu,Z.M.;Liang,X.M.,Synthesisandshapeevolutionofmonodispersebasicmagnesiumcarbonatemicrospheres.CrystalGrowth&Design2007,7,(2),337-342.
4.Zhou,D.Y.;Xu,Q.;Xue,X.Y.;Zhang,F.F.;Liang,X.M.,IdentificationofO-diglycosylflavanonesinFructusaurantiibyliquidchromatographywithelectrosprayionizationandcollision-induceddissociationmassspectrometry.JournalofPharmaceuticalandBiomedicalAnalysis2006,42,(4),441-448.
5.Zhao,H.X.;Xue,X.Y.;Xu,Q.;Zhang,F.F.;Liang,X.M.,Gaschromatographicpeakidentificationforpolybrominateddiphenylethersunderdifferenttemperatureprograms.JournalofChromatographyA2006,1107,(1-2),248-256.
6.Zhang,Z.P.;Zheng,Y.J.;Ni,Y.W.;Liu,Z.M.;Chen,J.P.;Liang,X.M.,Temperature-andpH-dependentmorphologyandFT-IRanalysisofmagnesiumcarbonatehydrates.JournalofPhysicalChemistryB2006,110,(26),12969-12973.
7.Zhang,Z.P.;Zhang,S.G.;Chen,J.P.;Liu,Z.M.;Liang,X.M.,CharacterizationofthesurfacepropertiesofMg/Aloxidesbythesolvationparametermodel.JournalofChromatographyA2006,1115,(1-2),58-63.
8.Zhang,X.L.;Martens,D.;Kramer,P.M.;Kettrup,A.A.;Liang,X.M.,Developmentandapplicationofasol-gelimmunosorbent-basedmethodforthedeterminationofisoproturoninsurfacewater.JournalofChromatographyA2006,1102,(1-2),84-90.
9.Zhang,X.L.;Martens,D.;Kramer,P.M.;Kettrup,A.A.;Liang,X.M.,On-lineimmunoaffinitycolumn-liquidchromatography-tandemmassspectrometrymethodfortraceanalysisofdiuroninwastewatertreatmentplanteffluentsample.JournalofChromatographyA2006,1133,(1-2),112-118.
10.Zhang,G.F.;Liu,R.H.;Xu,Q.;Ma,L.X.;Liang,X.M.,Sodiumnitrite-catalyzedoxybrominationofaromaticcompoundsandarylketoneswithacombinationofhydrobromicacidandmolecularoxygenundermildconditions.AdvancedSynthesis&Catalysis2006,348,(7-8),862-866.
11.Zeng,Q.H.;Hu,X.P.;Duan,Z.C.;Liang,X.M.;Zheng,Z.,Unsymmetricalferrocenylethylamine-derivedmonophosphoramidites:HighlyefficientchiralligandsforRh-catalyzedenantioselectivehydrogenationofenamidesandalpha-dehydroaminoacidderivatives.JournalofOrganicChemistry2006,71,(1),393-396.
12.Zeng,G.F.;Xiao,H.B.;Liu,J.X.;Liang,X.M.,IdentificationofphenolicconstituentsinRadixSalviamiltiorrhizaebyliquidchromatography/electrosprayionizationmassspectrometry.RapidCommunicationsinMassSpectrometry2006,20,(3),499-506.
13.Wang,N.W.;Liu,R.H.;Xu,Q.;Liang,X.M.,N-hydroxysuccinimide-promotedoxidationofprimaryalcoholsandaldehydestoformactiveesterswithhypervalent(III)iodine.ChemistryLetters2006,35,(6),566-567.
14.Ma,X.;Xiao,H.B.;Liang,X.M.,IdentificationofginsenosidesinPanaxquinquefoliumbyLC-MS.Chromatographia2006,64,(1-2),31-36.
15.Guo,Z.M.;Lei,A.W.;Liang,X.M.;Xu,Q.,Clickchemistry:anewfacileandefficientstrategyforpreparationoffunctionalizedHPLCpackings.ChemicalCommunications2006,(43),4512-4514.
16.Zhao,H.X.;Zhang,Q.;Xue,X.Y.;Liang,X.M.;Kettrup,A.,Predictinggaschromatographicretentiontimesof209polybrominateddiphenyls(PBBs)fordifferenttemperatureprograms.AnalyticalandBioanalyticalChemistry2005,382,(5),1304-1310.
17.Zhang,Y.;Xu,Q.;Zhang,X.Z.;Chen,J.P.;Liang,X.M.;Kettrup,A.,High-performanceliquidchromatography-tandemmassspectrometryforidentificationofisoflavonesanddescriptionofthebiotransformationofkudzuroot.AnalyticalandBioanalyticalChemistry2005,383,(5),787-796.
18.Zhang,Y.;Chen,J.P.;Zhang,C.Z.;Wu,W.Z.;Liang,X.M.,Analysisoftheestrogeniccomponentsinkudzurootbybioassayandhighperformanceliquidchromatography.JournalofSteroidBiochemistryandMolecularBiology2005,94,(4),375-381.
19.Zhang,C.Z.;Zhang,Y.F.;Chen,J.P.;Liang,X.M.,Purificationandcharacterizationofbaicalin-beta-D-glucuronidasehydrolyzingbaicalintobaicaleinfromfreshrootsofScutellariaviscidulaBge.ProcessBiochemistry2005,40,(5),1911-1915.
20.Zeng,Q.H.;Hu,X.P.;Duan,Z.C.;Liang,X.M.;Zheng,Z.,Newunsymmetricalhybridferrocenylphosphine-phosphoramiditeligandsderivedfromH-8-BINOLforhighlyefficientRh-catalyzedenantioselectivehydrogenation.Tetrahedron-Asymmetry2005,16,(6),1233-1238.
21.Yu,W.Y.;Zhang,H.;Huang,W.D.;Chen,J.P.;Liang,X.M.,Confirmationandidentificationoftheimpuritiesinmetolachlorusinggaschromatographyinterfacedwithorthogonalaccelerationtime-of-flightmassspectrometry(GC-oaTOFMS).Talanta2005,65,(1),172-178.
22.Wang,S.S.;Zhao,W.H.;Han,X.W.;Liang,X.M.,TwonewiridoidglycosidesfromtheTibetanfolkmedicineSwertiafranchetiana.Chemical&PharmaceuticalBulletin2005,53,(6),674-676.
23.Wang,N.W.;Liu,R.H.;Chen,J.P.;Liang,X.M.,NaNO2-activated,iron-TEMPOcatalystsystemforaerobicalcoholoxidationundermildconditions.ChemicalCommunications2005,(42),5322-5324.
24.Wang,L.X.;Zhang,L.F.;Wang,S.S.;Xiao,H.B.;Liang,X.M.,DiscriminatingthexanthonesinanextractofSwertiafranchetianabyretentionparameters.PhytochemicalAnalysis2005,16,(1),34-38.
25.Wang,J.C.;Guo,R.B.;Chen,J.P.;Zhang,Q.;Liang,X.M.,Phenylureaherbicides-selectivepolymerpreparedbymolecularimprintingusingN-(4-isopropylphenyl)-N’-butyleneureaasdummytemplate.AnalyticaChimicaActa2005,540,(2),307-315.
26.Ma,X.Q.;Liang,X.M.;Xu,Q.;Zhang,X.Z.;Xiao,H.B.,IdentificationofginsenosidesinrootsofPanaxginsengbyHPLC-APCI/MS.PhytochemicalAnalysis2005,16,(3),181-187.
27.Liu,R.H.;Dong,C.Y.;Liang,X.M.;Wang,X.J.;Hu,X.Q.,Highlyefficientcatalyticaerobicoxidationsofbenzylicalcoholsinwater.JournalofOrganicChemistry2005,70,(2),729-731.
28.Liang,X.M.;Fu,D.M.;Liu,R.H.;Zhang,Q.;Zhang,T.Y.;Hu,X.Q.,HighlyefficientNaNO2-Catalyzeddestructionoftrichlorophenolusingmolecularoxygen.AngewandteChemie-InternationalEdition2005,44,(34),5520-5523.
29.Fu,S.P.;Zhang,F.;Zhang,X.Z.;Xu,Q.;Xiao,H.B.;Liang,X.M.,PhysicochemicalcharacterizationoftheStrychnosalkaloidsbycapillaryzoneelectrophoresis.AnalyticalSciences2005,21,(11),1303-1308.