程家高副教授
电话:64252945－8310E-mail:jgcheng@ecust.edu.cn;jgcheng78@gmail.com
个人简介

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程家高：博士，副教授，1978年6月生。2000年7月毕业于山东曲阜师范大学化学系获学士学位；同年9月考入中科院上海药物研究所攻读博士学位（硕博连读）师从陈凯先院士和蒋华良研究员，2005年7月获有机化学药物设计方向博士学位；同年9月进入华东理工大学药学院进行博士后研究，合作导师唐赟教授、李忠教授；2007年9月博士后出站留校在药物化工所工作，主要从事从事计算化学、药物设计和分子模拟研究。
在J.Org.Chem.;Chem.Phys.Lett.;QSAR&CombinatorialScience;J.Phys.Org.Chem.;Bioorg.Med.Chem.;Proteins;BiophysicalJ.;TetrahedronLett.;J.Phys.Chem.A;J.Phys.Chem.B等国际重要学术期刊上外发表外文SCI论文20余篇。作为课题负责人，先后主持国家自然科学基金一项、省部级科研基金三项、省部级重点实验室开放基金2项、指导国家大学生创新实验计划一项。

近三年（2007-今）发表的论文

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1.TingtingCao,YipeiMa,XiuhuaYan,JiagaoCheng*,YouhuaLuo,LimingHe,WeiliangZhu*.“IsFreeCyclooctatetraeneDianionanAromaticSystem?AQuantumChemistryStudy”,ChineseJournalofChemistry2009,27,1914-1918(*通讯作者)
2.FengFan,ZhiqiYou,ZhongLi,JiagaoCheng,YunTang,ZhenhuaTang.“AButterflyEffect:HighlyInsecticidalResistanceCausedbyOnlyaConservativeResidueMutatedofDrosophilaMelanogasterAcetylcholinesterase”,JournalofMolecularModeling,2009,publishedonline,DOI:10.1007/s00894-009-0474-5
3.FengFan,JiagaoCheng,ZhongLi*,XiaoyongXu,XuhongQian*.“NoveldimerbaseddescriptorswithsolvationalcomputationforQSARstudyofoxadiazoylbenzoyl-ureasasnovelisect-growthregulators”.JournalofComputationalChemistry.2009,publishedonline,DOI:10.1002/jcc.2135
4.FengFan,JinZhu,ShuaishuaiNi,JiagaoCheng*,YunTang,CongminKang,JianLi*,HualiangJiang.“PharmacophoreRefinementand3D-QSARStudiesofInhibitorsofCyclophilinAContainingAmideLinker”QSAR&CombinatorialScience,2009,28,183-193(*通讯作者)
5.LingyanHe§,JiagaoCheng§,TaoWang,CaimeiLi,ZhenGong,HongLiu,Bu-BingZeng,HualiangJiang,WeiliangZhu,"Cation-πcomplexesformedbetweencyclooctantetraeneandalkalineearthmetals:predictedandrecordedNMRfeatures",Chem.Phys.Lett.2008,462,45-58.(§并列第一作者）
6.JiagaoCheng,WeiLiangZhu,YanLiWang,XiuHuaYan,ZhongLi,YunTang,HuaLiangJiang,"TheOpen-CloseMechanismofM2ChannelProteininInfluenzaAVirus:AComputationalStudyontheHydrogenBondsandCation-piinteractionsamongHis37andTrp41",Sci.ChinaSer.B-Chem,2008,51,768-775.
7.JiagaoCheng,XiaoMinLuo,XiuHuaYan,ZhongLi,YunTang,HuaLiangJiang，WeiLiangZhu,"ResearchProgressinCation-piinteractions",Sci.ChinaSer.B-Chem,2008,51,709-717.
8.WeihuaLi,YunTang,HongLiu,JiagaoCheng,WeiliangZhu,andHualiangJiang.“ProbingligandbindingmodesofhumancytochromeP4502J2byhomologymodeling,moleculardynamicssimulation,andflexiblemoleculardocking”.Proteins:Structure,Functions,andBioinformatics,2008,71,938-949
9.JiagaoCheng,ZhenGong,WeiliangZhu,YunTang,WeihuaLi,ZhongLi,HualiangJiang.“Cationsittinginaromaticcages:abinitiocomputationalstudiesontetramethylammonium–(benzene)n(n=3–4)complexes”J.Phys.Org.Chem.,2007,20,448-457
10.YanliWang,JiagaoCheng,XuhongQian,ZhongLi.“ActionsbetweenneonicotinoidsandkeyresiduesofinsectnAChRbasedonanabinitioquantumchemistrystudy:Hydrogenbondingandcooperativeπ—πinteraction”.Bioorgan.&.Med.Chem.2007,15,2624-2630.
11.FeiZheng,RongjianSa,JiagaoCheng,HualiangJiang,JianhuaShen.“Carbocation-πinteractionwithCar-Parrinellomoleculardynamics:Abinitiomoleculardynamicsinvestigationofcomplexofmethylcationwithbenzene”.Chem.Phys.Lett.2007,435,24-28.
12.XifengLi,DahaiZhang,UkLee,XianguoLi,JiagaoCheng,WeiliangZhu,JeeHJung,HongDaeChoi,ByengWhaSon.“BromomyrothenoneBandBotrytinone,CyclopentenoneDerivativesfromaMarineIsolateoftheFungusBotrytis”.J.Nat.Prod.2007,70,307-309.
13.WeiFu,JianhuaShen,Xiaomin,Luo,WeiliangZhu,JiagaoCheng,KunqianYu,JamesMBriggs,GuozhangJin,KaixianChen,HualiangJiang.“DopamineD1ReceptorAgonistandD2ReceptorAntagonistEffectsoftheNaturalProduct(-)-Stepholidine(SPD):MolecularModelingandDynamicsSimulations"BiophysicalJournal2007,93,1431-1441.

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