杨红
职称：副教授
邮箱：yanghongyh@uestc.edu.cn
所在系别：生物技术系
研究领域：纳米生物医学，生物材料



教育背景
1992年09月—1996年06月，西南大学，生命科学学院，生物学专业，本科2000年09月—2003年06月，重庆大学，生物工程学院，生物医学工程专业，硕士2005年09月—2010年06月，电子科技大学，生命科学与技术学院，生物医学工程专业，博士
工作履历
2012年08月—今，电子科技大学，生命科学与技术学院，副教授2004年09月—2012年07月，电子科技大学，生命科学与技术学院，讲师1996年07月—2000年06月，西南大学，生命科学学院，助教
科学研究
研究概况
长期从事多功能化基因/药物靶向输送系统和微纳生物材料方面的研究，研究特色明显，已发表SCI论文60余篇，其中第一或通讯作者论文20余篇。主持国家自然科学基金青年项目一项，面上项目两项，四川省科技计划项目一项。
代表性成果
1.Tingting Li, Yue Geng, Hanxi Zhang, Jing Wang, Yi Feng, Zhongyuan Chen, Xiaoxue Xie, Xiang Qin, Shun Li, Chunhui Wu, Yiyao Liu* & Hong Yang*. (2020) A versatile nanoplatform for synergistic chemophotothermal therapy and multimodal imaging against breast cancer. Expert Opinion on Drug Delivery. VOL. 17, NO. 5, 725–7332.Xie X,?Chen Y,?Chen Z,?Feng Y,?Wang J,?Li T,?Li S,?Qin X,?Wu C,?Zheng C,?Zhu J,?You F,?Liu Y*,?Yang H*.（2019）Polymeric Hybrid Nanomicelles for Cancer Theranostics: An Efficient and Precise Anticancer Strategy for the Codelivery of?Doxorubicin/miR-34a?and?Magnetic?Resonance?Imaging. ?ACS Appl. Mater. Interfaces. 11, 43865?438783.Yang H, Shen X, Yan J, Xie X, Chen Z, Li T, Li S, Qin X, Wu C,?Liu Y*. (2018) Charge-reversal functionalized PLGA nanobubbles as theranostic agents for ultrasonic imaging-guided combination therapy. Biomaterials Science. 6: 2426-24394.Yang H, Zhang C, Li T, Shen X, Chen Z, Xie X, Li S, Qin X, Wu C, Liu Y*. (2017) Rational design of multifunctional polymeric micelles with stimuli-responsive for imaging-guided combination cancer therapy. Journal of Biomedical Nanotechnology. 13(10): 1221-1234.5.Yang, Hong; Chen, Yin; Chen, Zhongyuan; Geng, Yue; Xie, Xiaoxue; Shen, Xue; Li, Tingting; Li, Shun; Wu, Chunhui; Liu, Yiyao. (2017) Chemo-photodynamic combined gene therapy and dual-modal cancer imaging achieved by pH-responsive alginate/chitosan multilayer-modified magnetic mesoporous silica nanocomposites. Biomaterials science. 5: 1001–1013.6.Yang H, Xu M, Shen X, Li T, Yan J, Zhang C, Wu C, Zeng H, Liu Y*. (2016) Chitosan hybrid nanoparticles as a theranostic platform for targeted doxorubicin/VEGF shRNA co-delivery and dual-modality fluorescence imaging. RSC Advances. 6: 29685-29696.7.Yang H, Guan L, Li S, Jiang Y, Xiong N, Li L, Wu C, Zeng H, Liu Y*. (2016) Mechanosensitive caveolin-1 activation-induced PI3K/Akt/mTOR signaling pathway promotes breast cancer motility, invadopodia formation and metastasis in vivo. Oncotarget. 7(13): 16227-16247. 8.Yang H, Deng L, Li T, Shen X, Yan J, Zuo L, Wu C, Liu Y*. (2015) Multifunctional PLGA nanobubbles as theranostic agents: Combining doxorubicin and P-gp siRNA co-delivery into human breast cancer cells and ultrasound cellular imaging. Journal of Biomedical Nanotechnology. 11: 2124-2136. 9.Yang Hong *，Li Tingting , Chen Ying , Xu Mingming , Li Ying . (2015) VCAM-1-targeted silica nanoparticles doped with FITC and Fe3O4 for dual-mode cellular imaging of LPS-induced inflammatory endothelial cells. Journal of Controlled Release. 23:e40-e41, doi:10.1016/j.jconrel.2015.05.065.10.Yang H, Li Y, Chen Y, Wu C, Dong X, Li T, Xu M, Liu Y*. (2014) Multifunctional core/shell nanoparticles cross-linked polyetherimide-folic acid as efficient Notch-1 siRNA carrier for targeted killing of breast cancer. Scientific Reports. 4: 7072, DOI: 10.1038/srep07072.11.Yang H, Shi M, Xu M, Li Y, Wu C, Liu Y*. (2013) Multifunctional silica nanoparticles as theranostic agents: combining VEGF gene delivery and dual-modality cellular imaging. Journal of Controlled Release. 172(1): e120-e121.12.Yang H, Zhao F, Li Y, Xu M, Li L, Wu C, Miyoshi H, Liu Y*. (2013) VCAM-1-targeted core/shell nanoparticles for selective adhesion and delivery to endothelial cells with lipopolysaccharide-induced inflammation under shear flow and cellular magnetic resonance imaging in vitro. International Journal of Nanomedicine. 8: 1897-1906.13.Yang H, Zhang L, Xiong X,?Liu Y*.?(2011)?Specific adhesion and accumulation of VCAM-1-targeted ultrasound microbubbles to inflammatory endothelial cells under hemodynamic shear flow simulation.?Journal of Controlled Release. 152(s1): e227-e229. 14.Yang H, Lou C, Xu M, Wu C, Miyoshi H,?Liu Y*.?(2011)?Investigation of folate conjugated fluorescent silica nanoparticles for targeting delivery to folate receptor-positive tumors and their internalization mechanism.?International Journal of Nanomedicine. 6: 2023-2032. 15.Yang H, Xiong X, Zhang L, Wu C,?Liu Y*.?(2011)?Adhesion of bio-functionalized ultrasound microbubbles to endothelial cells by targeting to vascular cell adhesion molecule-1 under shear flow.?International Journal of Nanomedicine. 6: 2043-2051. 16.Yang H, Liu Z, Liu Y*, Lou C, Ren Z, Miyoshi H.?(2010)?Vascular gene transfer and drug delivery?in vitro?by using low frequency ultrasound with microbubbles.?Acta Pharmacologica Sinca. 31: 515-522. 17.Yang H, Miyoshi H, Lou C, Ren Z, Liu Y*.?(2010)?Preparation, characterization and release of methyl viologen from a novel nanoparticle delivery system with double shells of silica and PLGA.?Chinese Science Bulletin. 55: 263-267. 1.青年基金，叶酸受体靶向的超顺磁/荧光/VEGF siRNA 多功能硅纳米载体的抗肿瘤作用及其成像规律研究，（**）2012.10-2015.12，23万元，主持。2.国家自然科学基金面上项目，基因/化疗药物共输送的氧化还原响应性PLGA超声纳米泡协同抗肿瘤作用及其超声成像研究（**）2014.09-2018.12，85万元，主持。3.国家自然科学基金面上项目，发光/磁性杂合靶向纳米胶束联合阿霉素和miR-34a治疗肿瘤协同增敏和双模态成像研究，（**）2017.1-2020.12，58万元，主持。4.四川省科技计划项目，复合纳米胶束联合DOX和miRNAs用于成像引导下的肿瘤治疗，（2019YJ0184），2019.01-2021.12，10万元，主持。刘贻尧，徐敏，杨红，吴春惠，曾红娟. 一种碳量子点的制备方法及其应用. 授权号：ZL .0.
教育教学
本科生课程
《生命科学导论》、《生物技术制药》
研究生课程
《高级细胞生物学》
招生专业

个人/团队主页
http://biophysics.uestc.edu.cn/
职称 副教授 邮箱 yanghongyh@uestc.edu.cn
所在系别 生物技术系 研究领域 纳米生物医学，生物材料
科学研究 招生专业
联系方式 办公地址
团队联系方式 教育教学 1992年09月—1996年06月，西南大学，生命科学学院，生物学专业，本科
2000年09月—2003年06月，重庆大学，生物工程学院，生物医学工程专业，硕士
2005年09月—2010年06月，电子科技大学，生命科学与技术学院，生物医学工程专业，博士
工作履历 2012年08月—今，电子科技大学，生命科学与技术学院，副教授
2004年09月—2012年07月，电子科技大学，生命科学与技术学院，讲师
1996年07月—2000年06月，西南大学，生命科学学院，助教 研究概况 长期从事多功能化基因/药物靶向输送系统和微纳生物材料方面的研究，研究特色明显，已发表SCI论文60余篇，其中第一或通讯作者论文20余篇。主持国家自然科学基金青年项目一项，面上项目两项，四川省科技计划项目一项。
代表性成果 1.Tingting Li, Yue Geng, Hanxi Zhang, Jing Wang, Yi Feng, Zhongyuan Chen, Xiaoxue Xie, Xiang Qin, Shun Li, Chunhui Wu, Yiyao Liu* & Hong Yang*. (2020) A versatile nanoplatform for synergistic chemophotothermal therapy and multimodal imaging against breast cancer. Expert Opinion on Drug Delivery. VOL. 17, NO. 5, 725–733
2.Xie X,?Chen Y,?Chen Z,?Feng Y,?Wang J,?Li T,?Li S,?Qin X,?Wu C,?Zheng C,?Zhu J,?You F,?Liu Y*,?Yang H*.（2019）Polymeric Hybrid Nanomicelles for Cancer Theranostics: An Efficient and Precise Anticancer Strategy for the Codelivery of?Doxorubicin/miR-34a?and?Magnetic?Resonance?Imaging. ?ACS Appl. Mater. Interfaces. 11, 43865?43878
3.Yang H, Shen X, Yan J, Xie X, Chen Z, Li T, Li S, Qin X, Wu C,?Liu Y*. (2018) Charge-reversal functionalized PLGA nanobubbles as theranostic agents for ultrasonic imaging-guided combination therapy. Biomaterials Science. 6: 2426-2439
4.Yang H, Zhang C, Li T, Shen X, Chen Z, Xie X, Li S, Qin X, Wu C, Liu Y*. (2017) Rational design of multifunctional polymeric micelles with stimuli-responsive for imaging-guided combination cancer therapy. Journal of Biomedical Nanotechnology. 13(10): 1221-1234.
5.Yang, Hong; Chen, Yin; Chen, Zhongyuan; Geng, Yue; Xie, Xiaoxue; Shen, Xue; Li, Tingting; Li, Shun; Wu, Chunhui; Liu, Yiyao. (2017) Chemo-photodynamic combined gene therapy and dual-modal cancer imaging achieved by pH-responsive alginate/chitosan multilayer-modified magnetic mesoporous silica nanocomposites. Biomaterials science. 5: 1001–1013.
6.Yang H, Xu M, Shen X, Li T, Yan J, Zhang C, Wu C, Zeng H, Liu Y*. (2016) Chitosan hybrid nanoparticles as a theranostic platform for targeted doxorubicin/VEGF shRNA co-delivery and dual-modality fluorescence imaging. RSC Advances. 6: 29685-29696.
7.Yang H, Guan L, Li S, Jiang Y, Xiong N, Li L, Wu C, Zeng H, Liu Y*. (2016) Mechanosensitive caveolin-1 activation-induced PI3K/Akt/mTOR signaling pathway promotes breast cancer motility, invadopodia formation and metastasis in vivo. Oncotarget. 7(13): 16227-16247.
8.Yang H, Deng L, Li T, Shen X, Yan J, Zuo L, Wu C, Liu Y*. (2015) Multifunctional PLGA nanobubbles as theranostic agents: Combining doxorubicin and P-gp siRNA co-delivery into human breast cancer cells and ultrasound cellular imaging. Journal of Biomedical Nanotechnology. 11: 2124-2136.
9.Yang Hong *，Li Tingting , Chen Ying , Xu Mingming , Li Ying . (2015) VCAM-1-targeted silica nanoparticles doped with FITC and Fe3O4 for dual-mode cellular imaging of LPS-induced inflammatory endothelial cells. Journal of Controlled Release. 23:e40-e41, doi:10.1016/j.jconrel.2015.05.065.
10.Yang H, Li Y, Chen Y, Wu C, Dong X, Li T, Xu M, Liu Y*. (2014) Multifunctional core/shell nanoparticles cross-linked polyetherimide-folic acid as efficient Notch-1 siRNA carrier for targeted killing of breast cancer. Scientific Reports. 4: 7072, DOI: 10.1038/srep07072.
11.Yang H, Shi M, Xu M, Li Y, Wu C, Liu Y*. (2013) Multifunctional silica nanoparticles as theranostic agents: combining VEGF gene delivery and dual-modality cellular imaging. Journal of Controlled Release. 172(1): e120-e121.
12.Yang H, Zhao F, Li Y, Xu M, Li L, Wu C, Miyoshi H, Liu Y*. (2013) VCAM-1-targeted core/shell nanoparticles for selective adhesion and delivery to endothelial cells with lipopolysaccharide-induced inflammation under shear flow and cellular magnetic resonance imaging in vitro. International Journal of Nanomedicine. 8: 1897-1906.
13.Yang H, Zhang L, Xiong X,?Liu Y*.?(2011)?Specific adhesion and accumulation of VCAM-1-targeted ultrasound microbubbles to inflammatory endothelial cells under hemodynamic shear flow simulation.?Journal of Controlled Release. 152(s1): e227-e229.
14.Yang H, Lou C, Xu M, Wu C, Miyoshi H,?Liu Y*.?(2011)?Investigation of folate conjugated fluorescent silica nanoparticles for targeting delivery to folate receptor-positive tumors and their internalization mechanism.?International Journal of Nanomedicine. 6: 2023-2032.
15.Yang H, Xiong X, Zhang L, Wu C,?Liu Y*.?(2011)?Adhesion of bio-functionalized ultrasound microbubbles to endothelial cells by targeting to vascular cell adhesion molecule-1 under shear flow.?International Journal of Nanomedicine. 6: 2043-2051.
16.Yang H, Liu Z, Liu Y*, Lou C, Ren Z, Miyoshi H.?(2010)?Vascular gene transfer and drug delivery?in vitro?by using low frequency ultrasound with microbubbles.?Acta Pharmacologica Sinca. 31: 515-522.
17.Yang H, Miyoshi H, Lou C, Ren Z, Liu Y*.?(2010)?Preparation, characterization and release of methyl viologen from a novel nanoparticle delivery system with double shells of silica and PLGA.?Chinese Science Bulletin. 55: 263-267.

1.青年基金，叶酸受体靶向的超顺磁/荧光/VEGF siRNA 多功能硅纳米载体的抗肿瘤作用及其成像规律研究，（**）2012.10-2015.12，23万元，主持。
2.国家自然科学基金面上项目，基因/化疗药物共输送的氧化还原响应性PLGA超声纳米泡协同抗肿瘤作用及其超声成像研究（**）2014.09-2018.12，85万元，主持。
3.国家自然科学基金面上项目，发光/磁性杂合靶向纳米胶束联合阿霉素和miR-34a治疗肿瘤协同增敏和双模态成像研究，（**）2017.1-2020.12，58万元，主持。
4.四川省科技计划项目，复合纳米胶束联合DOX和miRNAs用于成像引导下的肿瘤治疗，（2019YJ0184），2019.01-2021.12，10万元，主持。

刘贻尧，徐敏，杨红，吴春惠，曾红娟. 一种碳量子点的制备方法及其应用. 授权号：ZL .0. 教育教学
本科生课程 《生命科学导论》、《生物技术制药》 研究生课程 《高级细胞生物学》
个人团队主页 http://biophysics.uestc.edu.cn/ 代表性学术成果
荣誉与奖励 团队主页