王钊 邮箱:zhaowang@uestc.edu.cn
电话:
系别:物理电子系
职称:教授
教师个人主页:
教师简介
教育背景
2008-2013 Case Western Reserve University(美国),生物医学工程专业,博士学位
2006-2008 西安交通大学,生物医学工程专业,硕士学位
2002-2006 西安交通大学,生物医学工程专业,学士学位
工作履历
2018.07-至今 电子科技大学,教授
2013-2017 麻省理工学院(美国),博士后
科学研究
王钊教授的主要研究方向为医学影像、光学仪器、人工智能、医学图像处理、智能医疗器械等,现已出版英文学术专著和章节2部,发表SCI论文30余篇,国际会议论文或报告30余次,申请并获授权国际专利2项,担任10多个国际知名期刊的审稿人,论文被引700余次,H因子为18。实验室欢迎博士生、硕士生报考,也欢迎有意保研或积累科研工作经验的本科生和我们随时联系,特别是对医学影像和人工智能(AI)感兴趣的同学。(请发简历至zhaowang92@uestc.edu.cn)。
研究领域
下一代光学相干断层成像技术
光学相干断层成像技术(Optical Coherence Tomography, OCT)是一种基于近红外光干涉原理的生物医学三维断层成像技术,一般具有毫米级别的测量深度和微米级别的分辨率,100KHz-上兆Hz的成像速度,灵敏度高,已成为眼科领域诊断的金标(图1A-D),全球临床累计使用超过1亿次。
我们致力于开发成像距离更远、分辨率更高、功能更强大的下一代OCT成像技术。其中一个方向是研发宏观OCT成像技术,将OCT的应用领域拓展到机器视觉、三维传真、雷达勘探、手术术中导航、精密制造等领域。图1E-F是我们最近研发的米级三维OCT成像技术,在世界上首次实现了立方米级的成像景深和微米级别的分辨率。另一个方向是发展高分辨、多功能、多模态成像技术,在提供结构信息的同时获取光谱、血流、偏振、荧光等其他信息,用于临床疾病的诊断和生物医学基础研究。
图1:光学相干断层成像技术。(A-D)微米分辨率三维断层健康人眼视网膜活体成像,标尺为1mm。(E)宏观范围立方米级成像,假人大小与正常成年人类似。(F)三维物体成像与重建。参考文献:Z. Wang et al, " Optica 3, 1496-1503 (2016)
微型内窥成像技术
近红外光对人体的穿透力有限,如果要对人体内部器官成像并对疾病做出诊断,则必须将成像系统做成微型探头伸入到体内。我们致力于研发下一代内窥成像探头,可用于对人体消化道疾病特别是早期癌症的诊断、也可用于心血管、泌尿系统、神经系统等疾病的辅助诊断和手术导航。图2是我们参与研发的可吞服式系绳胶囊探头、可扩张式气球内窥探头,微型微电机内窥探头技术以及在活体病人中获得的三维图像。
图2:微型内窥成像技术。(左上)可吞服式系绳胶囊活体病人成像,标尺为1mm。(右上)基于微电机可扩张式气球探头所得的口腔黏膜血管造影成像。(下)基于微电机探头的活体食道成像。参考文献:K. Liang*, Z. Wang* et al, Optica 1(5) (2018), H.C. Lee et al, Gastrointestinal Endoscopy, (2017), H.C. Lee et al, Biomed. Opt. Express 7(8), (2016), K. Liang et al. Am. J. Gastroenterol. 111, 1664 (2016), Z. Wang et al. Biomed. Opt. Express, 6(7), (2015)
目前,2017年中国的医疗器械市场已逾4500亿美金,且增长率为19.67%,超越日本成为了全球第二大器械市场。然而,高端医疗影像设备仍然被国际巨头垄断,国产设备更多是简单模仿,在产品原创、核心部件、技术细节、品牌、平台等方面存在全方位差距。在此关乎人民健康的重要领域研发和落地具有自主知识产权的国产高端医疗影像设备具有重大意义。我们致力于研发下一代高端微型内窥成像技术以及其他智能医疗器械,在国际竞争中迈出重要一步。
人工智能和医学图像处理
医学成像技术已经成为各项疾病诊断的必需手段之一,由此产生的医学影像数据极其庞大,人工分析数据费时费力,不同医生做出的诊断和分析差别可能很大,且很多经济欠发达地区无法获取一流的诊断和及时的治疗,这些都在一定程度上造成了当今中国医疗资源分配不平衡、看病贵、看病难等问题。因此,发展人工智能和医学图像处理技术,减轻医生的负担,提高医生诊断的效率,促进标准化分析,获取多维诊断信息,对于尽早发现、治疗疾病,普及医疗资源,提高医疗效率有着重要的意义。然而,当前医学图像处理技术远远落后于相关成像技术的发展。我们致力于开发新颖的人工智能和医学图像处理技术用于各项疾病的智能诊断,特别是对于新兴领域如医学光学影像数据的处理是我们研究的重点。图3是我们已经研发的一些成果用于心血管、消化道、眼科等疾病的诊断。
图3:人工智能和医学图像处理技术。(A)冠状动脉纤维帽板块自动量化和三维显示。(B)代表性实验室重点研发的算法:基于Graph的图像分割算法以及深度学习网络。(C)动脉粥样化斑块侵蚀的自动识别。(D)血管支架的自动检测。(E)白内障手术导航和图像自动追踪。参考文献: L. Xing et al, Journal of the American College of Cardiology 69(20) (2017), Z. Wang et al, Coronary artery disease (2016). Z. Wang et al, IEEE Trans. Med. Imaging. 34(7) (2015), Z. Wang et al, Circ. Cardiovasc. Imaging (2014), Z. Wang et al, Biomed. Opt. Express. 3(6), 1413-1426 (2012)
近期,国家相继出台数十项政策性文件,对医疗领域提出人工智能发展要求。李克强总理2017年所做的政府工作报告中首次涉及了“人工智能”,强调要加快我国人工智能方面的技术研究与转换,推动人工智能技术的落地使用,提出将人工智能技术应用于医疗领域。工信部印发《促进新一代人工智能产业发展三年行动计划(2018-2020年)》通知中明确指出推动医学影像数据采集标准化与规范化,支持脑、肺、眼、骨、心脑血管、乳腺等典型疾病领域的医学影像辅助诊断技术研发,加快医疗影像辅助诊断系统的产品化及临床辅助应用。人工智能辅助诊断技术已成为国家重要战略目标,人工智能与大数据相结合是未来医疗健康领域的发展方向。
太赫兹成像技术
太赫兹频段泛指300GHz-3THz(或 100微米-1毫米)的电子波,介于近红外光与微波之间。太赫兹成像技术有很多独特的特性。相比近红外光,太赫兹波对很多材料具备更强的穿透力,特别是对于非导电材料,且没有X光一样的辐射;相比微波成像,太赫兹成像具备更高的分辨率,且对很多材料和生物大分子等具备光谱“Fingerprint”特性,因此在安全检测、疾病诊断、材料科学、质量控制等领域有极大的应用前景。目前,相比微波和光学成像技术,太赫兹成像技术还远不成熟,因此具有广阔的探索范围和产生新的技术突破的潜力。我们的研究兴趣是研发太赫兹相干断层成像技术以及太赫兹和光学成像的交叉与结合。
合作单位
我们的合作单位包括世界顶级院校和研究机构哈佛医学院、麻省总医院、麻省理工学院、哈尔滨医科大学、北京协和医院等。
学术成果
Invited Book Chapters
1. Z. Wang, D.L. Wilson, H.G. Bezerra and A.M. Rollins, “Image processing in intravascular OCT”. In W. Drexler and J.G. Fujimoto: Optical Coherence Tomography: Technology and Applications. Springer, (2015)
2. Z. Wang, “Exploring the Physics Behind Optical Coherence Tomography”, in Barlis, Jang, Serruys: Coronary Optical Coherence Tomography: A Clinical Guide, Springer, to appear in 2018
Peer-reviewed Journal Articles
1. Z. Wang, H.C. Lee, O.O. Ahsen, K. Liang, M. Figueiredo, Q. Huang, J. Fujimoto, and H. Mashimo, “Computer-Aided Analysis of Gland-Like Subsurface Hyposcattering Structures in Barrett’s Esophagus Using Optical Coherence Tomography”, Applied Sciences, 8(12), 2420 (2018)
2. O.O. Ahsen, K. Liang, H.C. Lee, M.G. Giacomelli, Z. Wang, B. Potsaid, M. Figueiredo, Q. Huang, V. Jayaraman, J.G. Fujimoto, and H. Mashimo. Assessment of Barrett’s Esophagus and Dysplasia with Ultrahigh-Speed Volumetric En Face and Cross-sectional Optical Coherence Tomography. Endoscopy (2018)
3. K. Liang*, Z. Wang*, O.O. Ahsen, H.C. Lee, B.M Potsaid, V. Jayaraman, A. Cable, H. Mashimo, X. Li, and J. G Fujimoto, “Cycloid Scanning for Wide field optical coherence tomography endomicroscopy and angiography in vivo”, Optica 1(5) (2018) *Co-first authors
4. O.O. Ahsen, H.C. Lee, K. Liang, Z. Wang, M. Figueiredo, Q. Huang, B. Potsaid, V. Jayaraman, J. G Fujimoto, H. Mashimo, “Ultrahigh-Speed Endoscopic Optical Coherence Tomography and Angiography Enables Delineation of Lateral Margins of Endoscopic Mucosal Resection: A Case Report”, Therap. Adv. Gastroenterol., 10(12), 931-936 (2017)
5. E. Yamamoto, L. Xing, T. Higuma, Y. Minami, K. Bryniarski, T. Zanchin, Z. Wang, A. D Aguirre, H. Lee, I. K. Jang, “Dynamic Neointimal Pattern After Drug-Eluting Stent Implantation Defined by Optical Coherence Tomography”, Coronary Artery Disease 28 (7), 557-563 (2017)
6. K. Liang, O.O. Ahsen, Z. Wang, H. Lee, W. Liang, B.M. Potsaid, T.H. Tsai, M. G. Giacomelli, V. Jayaraman, H. Mashimo, X. Li, and J. G. Fujimoto, "Endoscopic Forward-Viewing Optical Coherence Tomography and Angiography with MHz Swept Source," Opt. Lett. 42, 3193-3196 (2017)
7. Y. Minami, Z. Wang, A.D. Aguirre, D.S. Ong, C.J. Kim, S. Uemura, T. Soeda, H. Lee, J. Fujimoto, I.K. Jang, “Clinical Predictors for Lack of Favorable Vascular Response to Statin Therapy in Patients With Coronary Artery Disease: A Serial Optical Coherence Tomography Study”, J. Am. Heart Assoc., 6(11), e006241 (2017)
8. L. Xing, T. Higuma, Z. Wang, A. Aguirre, K. Mizuno, M. Takano, H.L. Dauerman, S. Park, Y. Jang, C.J. Kim, S.J. Kim, S.Y. Choi, T. Itoh, S. Uemura, H. Lowe, D.L. Walters, P. Barlis, S. Lee, A. Lerman, C. Toma, J. Wei, C. Tan, E. Yamamoto, K. Bryniarski, J. Dai, T. Zanchin, S. Zhang, B. Yu, H. Lee, J. Fujimoto, V. Fuster, I.K. Jang, “Clinical Significance of Lipid-Rich Plaque Detected by Optical Coherence Tomography: A 4-Year Follow-Up Study”; J. Am. Coll. Cardiol. 69(20) 2502-2513 (2017)
9. O.O. Ahsen, H.C. Lee, K. Liang, Z. Wang, M. Figueiredo, Q. Huang, B. Potsaid, V. Jayaraman, J.G. Fujimoto, H. Mashimo, “Association Between Cross-Sectional and En Face Image Features of Barrett's Esophagus and Dysplasia with Endoscopic Optical Coherence Tomography”, Gastroenterology, 152(5) S841-S842 (2017)
10. S. Hu, Y. Zhu, Y. Zhang, J. Dai, L. Li, H. Dauerman, T. Soeda, Z. Wang, H Lee, C. Wang, C. Zhe, Y. Wang, G. Zheng, S. Zhang, H. Jia, B. Yu, I.K. Jang, “Management and Outcome of Patients with Acute Coronary Syndrome Caused by Plaque Rupture Versus Plaque Erosion: An Intravascular Optical Coherence Tomography Study”, J. Am. Heart Assoc., 6(3) e004730 (2017)
11. H.C. Lee, O.O. Ahsen, K. Liang, Z. Wang, M. Figueiredo, M.G. Giacomelli, B. Potsaid, V. Jayaraman, A.E. Cable, Q. Huang, H. Mashimo and J.G. Fujimoto, “Endoscopic Optical Coherence Tomography Angiography for Dysplasia Detection in Barrett's Esophagus (with video)”, Gastrointestinal Endoscopy, 86(3) 476-484 (2017)
12. Z. Wang, B. Potsaid, L. Chen, C. Doerr, H.C. Lee, T. Nielson, V. Jayaraman, A. Cable, E. Swanson and J. G. Fujimoto, " Cubic Meter Volume Swept Source Optical Coherence Tomography," Optica 3(12) (2016)
13. H.C. Lee, O. O. Ahsen, K. Liang, G. Traverso, Z Wang, C. Cleveland, L. Booth, B. Potsaid, V. Jayaraman, A.E. Cable, H. Mashimo, R. Langer and J.G. Fujimoto “Circumferential Optical Coherence Tomography Angiography Imaging of the Swine Esophagus Using a Micromotor Balloon Catheter,” Biomed. Opt. Express 7(8), 2927-2942 (2016)
14. K. Liang, O. O. Ahsen, H.C. Lee, Z. Wang, B. Potsaid, M. Figueiredo, V. Jayaraman, A. Cable, Q. Huang, H. Mashimo and J. G. Fujimoto. “Volumetric mapping of Barrett’s Esophagus and dysplasia with en face optical coherence tomography tethered capsule,” Am. J. Gastroenterol. 111, 1664 (2016)
15. Z. Wang, Y.S. Cho, T. Soeda, Y. Minami, L. Xing, H. J, A. Aguirre, R. Vergallo, H. Lee, J.G. Fujimoto, B. Yu, I.K. Jang. “Three Dimensional Morphological Response of Lipid-Rich Coronary Plaques to Statin Therapy: A Serial Optical Coherence Tomography Study,” Coronary artery disease (2016).
16. D.S. Ong, J. S. Lee, T. Soeda, T. Higuma, Y. Minami, Z. Wang, H. Lee, H. Yokoyama, T. Yokota, K. Okumura, and I.K Jang. “Coronary Calcification and Plaque Vulnerability: An Optical Coherence Tomographic Study,” Circ. Cardiovasc. Imaging. 9:e003929, (2016)
17. Z. Wang, H.C. Lee, D. Vermeulen, L. Chen, T. Nielsen, S.Y. Park, A. Ghaemi, E. Swanson, C. Doerr and J. G. Fujimoto, "Silicon Photonic Integrated Circuit Swept-Source Optical Coherence Tomography Receiver with Dual Polarization, Dual Balanced, In-phase and Quadrature Detection," Biomed. Opt. Express, 6(7), 2562-2574 (2015)
18. Y. Minami, Z Wang, A. D. Aguirre, S. Lee, S. Uemura, T. Soeda, R. Vergallo, O. C. Raffel, P. Barlis, T. Itoh, H. Lee, J. Fujimoto and I.K Jang. "Quantitative Analysis of the Side-branch Orifice after Bifurcation Stenting using En-face Processing of OCT Images: A Comparison Between Xience V and Resolute Integrity Stents." Coronary artery disease (2015).
19. Y. Minami, D. Ong, S. Uemura, Z. Wang, A. Aguirre, S. Mukhopadhyay, T. Soeda, R. Vergallo, H. Jia, J. Tian, S. Hu, S.J. Kim, C.B. Park, H.Dauerman, S. Lee, I.K. Jang, “Impacts of Lesion Angle on Incidence and Distribution of Acute Vessel Wall Injuries and Strut Malapposition after Drug-eluting Stent Implantation Assessed by Optical Coherence Tomography,” Eur. Heart J. Cardiovasc. Imaging. (2015)
20. Z. Wang, M.W. Jenkins, G.C. Linderman, H.G. Bezerra, Y. Fujino, M.A. Costa, D.L. Wilson and A.M. Rollins, "3-D Stent Detection in Intravascular OCT Using a Bayesian Network and Graph Search," IEEE Trans. Med. Imaging. 34(7) (2015)
21. K. Liang, G. Traverso, H.C. Lee, O. O. Ahsen, Z. Wang, B. Potsaid, M. Giacomelli, V. Jayaraman, R. Barman, A. Cable, H. Mashimo, R. Langer, and J.G. Fujimoto, “Ultrahigh Speed En Face OCT Capsule for Endoscopic Imaging,” Biomed. Opt. Express, 6(4), 1146-1163 (2015) (
22. O.O. Ahsen, H.C. Lee, M.G. Giacomelli, Z. Wang, K. Liang, T.H. Tsai, B. Potsaid, H. Mashimo, and J.G. Fujimoto, “Correction of Rotational Distortion for Catheter-based en face OCT and OCT Angiography,” Opt. Lett. 39(20): 5973-5976 (2014)
23. R. Vergallo, M.I Papafaklis, T. Yonetsu, C.V. Bourantas, I. Andreou, Z. Wang, J.G. Fujimoto, I. McNulty, H. Lee, L.M. Biasucci, F. Crea, C.L. Feldman, L.K Michalis, P.H Stone and I.K. Jang. "Endothelial Shear Stress and Coronary Plaque Characteristics in Humans: A Combined Frequency-Domain Optical Coherence Tomography and Computational Fluid Dynamics Study," Circ. Cardiovasc. Imaging (2014)
24. M.Z. Galon, Z. Wang, H.G. Bezerra, P.A. Lemos, A. Schnell, D.L. Wilson, A.M. Rollins, M.A. Costa and G.F. Attizanni, “Differences Determined by Optical Coherence Tomography Volumetric Analysis in Non-Culprit Lesion Morphology and Inflammation in ST-Segment Elevation Myocardial Infarction and Stable Angina Pectoris Patients,” Catheter Cardiovasc Interv. (2014)
25. Z. Wang, H. Jia, J. Tian, T. Soeda, R. Vergallo, Y. Minami, H. Lee, A. Aguirre, J.G. Fujimoto and I.K. Jang, “Computer-Aided Image Analysis Algorithm to Enhance In Vivo Diagnosis of Plaque Erosion by Intravascular Optical Coherence Tomography,” Circ. Cardiovasc. Imaging (2014)
26. X. Fu, Z. Wang, H.Wang, Y. Wang, M.W. Jenkins, and A.M. Rollins. "Fiber-optic Catheter-based Polarization-sensitive OCT for Radio-Frequency Ablation Monitoring,” Opt. Lett. 39(17): 5066-5069 (2014)
27. Z. Wang, H.C. Lee, O.O. Ahsen, B. Lee, W. Choi, B. Potsaid, J. Liu, V. Jayaraman, A. Cable, M.F. Kraus, K. Liang, J. Homegger and J.G. Fujimoto, "Depth-encoded All-fiber Swept Source Polarization Sensitive OCT,” Biomed. Opt. Express. 5(9), 2931-2949 (2014)
28. J. Gao, Z. Wang, Y. Yang, W. Zhang, C. Tao, J. Guan and N. Rao, “A Novel Approach for Lie Detection Based on F-score and Extreme Learning Machine,” PloS one 8(6), e64704 (2013)
29. H. Lu, M. Gargesha, Z. Wang, D. Chamié, G.F. Attizani, T. Kanaya, S. Ray, M.A. Costa, A.M. Rollins, H.G. Bezerra, and D.L. Wilson, “Automatic Stent Detection in Intravascular OCT Images Using Bagged Decision Trees,” Biomed. Opt. Express. 3(11), 2809-2824 (2012)
30. D. Chamié, D. Prabhu, Z. Wang, H. Bezerra, A. Erglis, D.L. Wilson, A.M. Rollins and M.A. Costa, "Three-Dimensional Fourier-Domain Optical Coherence Tomography Imaging: Advantages and Future Development,” Curr. Cardiovasc. Imaging. 5(4), 221-230 (2012)
31. Z. Wang, D. Chamie, H.G. Bezerra, J. Kanovsky, H.Yamamoto, M.A. Costa and A.M. Rollins, "Volumetric Quantification of Fibrous Caps Using Intravascular Optical Coherence Tomography,” Biomed. Opt. Express. 3(6), 1413-1426 (2012)
32. S. Tahara, T. Morooka, Z. Wang, H.G. Bezerra, A.M. Rollins, D.I. Simon and M.A. Costa, "Intravascular Optical Coherence Tomography Detection of Atherosclerosis and Inflammation in Murine Aorta,” Arterioscler Thromb Vasc Biol. 32(5), 1150-1157 (2012)
33. W. Kang, H. Wang, Z. Wang, M.W. Jenkins, G.A. Isenberg, A. Chak and A.M. Rollins, "Motion Artifacts Associated with In Vivo Endoscopic OCT Images of the Esophagus,” Opt. Express. 19(21), 20722-20735 (2011)
34. T. Kubo, C. Xu, Z. Wang, N. van Ditzhuijzen and H.G. Bezerra, "Plaque and Thrombus Evaluation by Optical Coherence Tomography,” Int. J. Cardiovasc. Imaging. 27(2), 289-298 (2011)
35. D. Chamié, Z. Wang, H.G. Bezerra, A.M. Rollins and M.A. Costa, "Optical Coherence Tomography and Fibrous Cap Characterization,” Curr. Cardiovasc. Imaging. Rep. 4(4), 276-283 (2011)
36. Z. Wang, H. Kyono, H.G. Bezerra, H. Wang, M. Gargesha, C. Alraies, C. Xu, J.M. Schmitt, D.L. Wilson, M.A. Costa and A.M. Rollins, "Semi-automatic Segmentation and Quantification of Calcified Plaques in Intracoronary Optical Coherence Tomography Images,” J. Biomed. Opt. 15(6), 061711 (2010)
Selected Conference Presentations and Papers
1. Z. Wang, H.C. Lee, O.O Ahsen, K. Liang, M. Figueiredo, Q. Huang, J. G. Fujimoto and H. Mashimo, “Novel optical coherence tomography image analysis reveals subsquamous glandular structures as strong predictors of poorer response to radiofrequency ablation in Barrett’s esophagus,” in Digestive Disease Week (2016)
2. O.O Ahsen, H.C. Lee, K. Liang, Z. Wang, M. Figueiredo, M.G. Giacomelli, Q. Huang, B. Potsaid, V. Jayaraman, J. G. Fujimoto and H. Mashimo, “Endoscopic OCT Angiography Enables Visualization of Microvascular Changes to Assess RFA Treatment of Chronic Radiation Proctitis,” in Digestive Disease Week (2016)
3. H.C. Lee, O.O Ahsen, K. Liang, Z. Wang, M. Figueiredo, B. Potsaid, V. Jayaraman, Q. Huang, H. Mashimo and J. G. Fujimoto, “Ultrahigh speed endoscopic OCT angiography identifies both architectural and microvascular changes in patients with gastric antral vascular ectasia (GAVE) and received radiofrequency ablation treatment,” in Digestive Disease Week (2016)
4. Z. Wang, H. C. Lee, L. Chen, D. Vermeulen, T. Nielsen, S.Y. Park, A. Ghaemi, E. Swanson, C. Doerr, J. G. Fujimoto, “Miniaturized silicon photonic integrated swept source OCT receiver with dual polarization, dual balanced, in-phase and quadrature detection,” in SPIE Photonics West, San Francisco (2016) Oral presentation
5. K. Liang, Z. Wang, O.O Ahsen, H.C. Lee, M. Figueiredo, B. Potsaid, M.G. Giacomelli, V. Jayaraman, Q. Huang, H. Mashimo. Ultrahigh Speed Optical Coherence Tomography Imaging Capsule for En Face and Cross Sectional Mapping of Esophageal Architecture. Gastroenterology. 148(4):S-581 (2015)
6. Z. Wang, H.C. Lee, M.G. Giacomelli, K. Liang, O.O Ahsen, M. Figueiredo, Q. Huang, J. G. Fujimoto and H. Mashimo, “Automated Optical Coherence Tomography Image Processing for Three Dimensional Detection and Visualization of Subsurface Glands in Barrett’s Esophagus with Dysplasia. ” Gastroenterology, 148(4):S-580-S-581 (2015)
7. H.C. Lee, K. Liang, O.O. Ahsen, M.G. Giacomelli, Z. Wang, M. Figueiredo, Q. Huang, B. Potsaid, V. Jayaraman, and J. G. Fujimoto, "Ultrahigh Speed Endoscopic Optical Coherence Tomography and Angiography for Investigating Terminal Ileum With Chronic Inflammation," Gastroenterology, 148(4), S-581 (2015)
8. H.C. Lee, O.O. Ahsen, K. Liang, Z. Wang, M.G. Giacomelli, M. Figueiredo, Q. Huang, B. Potsaid, V. Jayaraman, and H. Mashimo, "Ultrahigh Speed Endoscopic Optical Coherence Tomography Angiography for Visualization of Subsurface Vasculature in Barrett's Esophagus and Dysplasia," Gastroenterology, 5(81), AB388 (2015)
9. O.O. Ahsen, H.C. Lee, K. Liang, M.G. Giacomelli, Z. Wang, M. Figueiredo, Q. Huang, B. Potsaid, V. Jayaraman, and J. G. Fujimoto, " En Face Optical Coherence Tomography Visualization of Mucosal Surface Patterns for Identifying Early Malignancy in the Upper GI Tract," Gastroenterology, 148(4), S-579 (2015)
10. H.C. Lee, O.O. Ahsen, K. Liang, M.G. Giacomelli, Z. Wang, B. Potsaid, V. Jayaraman, M. Figueiredo, Q. Huang, A. Cable, H. Mashimo and J.G. Fujimoto, “Ultrahigh Speed Endoscopic Structural and Angiographic OCT Imaging,” in SPIE Photonics West, San Francisco (2015) Oral presentation
11. O.O. Ahsen, H.C. Lee, K. Liang, M.G. Giacomelli, Z. Wang, B. Potsaid, M. Figueiredo, Q. Huang, A. Cable, V. Jayaraman, H. Mashimo and J.G. Fujimoto, “Ultrahigh Speed Endoscopic Optical Coherence Tomography For Structural And Angiographic Imaging,” in SPIE Photonics West, San Francisco (2015) Oral presentation
12. K. Liang, O.O Ahsen, Z. Wang, H.C. Lee, M.G. Giacomelli, B. Potsaid, V. Jayaraman, T. H. Tsai, W. Liang, A. Cable, H. Mashimo, X. Li and J.G. Fujimoto, “Ultrahigh Speed Swept Source OCT Forward Viewing Endomicroscopy,” in SPIE Photonics West, San Francisco (2015) Oral presentation
13. Z. Wang, H.C. Lee, O.O Ahsen, B. Lee, W. Choi, B. Potsaid, V. Jayaraman, A. Cable, K. Liang and J.G. Fujimoto, “Endoscopic and Ophthalmic Swept Source Polarization Sensitive OCT,” in SPIE Photonics West, San Francisco (2015). Oral presentation
14. H.C. Lee, O.O Ahsen, T.H Tsai, M.G. Giacomelli, Z. Wang, K. Liang, M. Figueiredo, Q. Huang, B. Potsaid, J.G. Fujimoto and H. Mashimo, “Novel Ultrahigh Speed Optical Coherence Tomography System and Micromotor Imaging Probe for Investigating Microvasculature in the Gastrointestinal Tract,” Gastroenterology. 146(5), S-520-S-521 (2014)
15. M.G. Giacomelli, T.H. Tsai, O.O Ahsen, H.C. Lee, K. Liang, Z. Wang, M. Figueiredo, Q. Huang, B. Potsaid, J.G. Fujimoto and H. Mashimo, “Ultrahigh Speed Micromotor Optical Coherence Tomography Enables Improved Access, Image Quality, and Maneuverability in Upper and Lower Endoscopy,” Gastroenterology. 146(5), S-521 (2014)
16. O.O. Ahsen, H.C. Lee, K. Liang, M.G. Giacomelli, T.H. Tsai, Z. Wang, M. Figueiredo, Q. Huang, B. Potsaid, J.G. Fujimoto and H. Mashimo, “Ultrahigh Speed Optical Coherence Tomography With Micromotor Imaging Probe Enables Three-Dimensional Visualization of Mucosal Surface Patterns in the Gastrointestinal Tract,” Gastroenterology. 146(5), S-519 (2014)
17. Z. Wang, W.J. Choi, J. J. Liu, M. F. Kraus, K. Mohler, B. Potsaid, B. Lee, J. Hornegger, and J. G. Fujimoto, "All-Fiber Multifunctional Swept Source Polarization Sensitive OCT," Investigative ophthalmology & visual science, vol. 55, pp. 1628-1628 (2014)
18. H. Lu, M. Jakl, Z. Wang, K. Tanaka, S. Ray, P. Cervinka, A.M. Rollins, H.G. Bezerra and D.L. Wilson, ” Evaluation of Highly Automated Software for Analyzing Intravascular Optical Coherence Tomography Pullbacks of Stents,” J. Am. Coll. Cardiol. 64, 11_S (2014)
19. Z. Wang, H. Jia, J. Tian, R. Vergallo, T. Soeda, A. Aguirre, J.G. Fujimoto and I.K. Jang, “Computer Aided Image Analysis to Enhance In Vivo Diagnosis of Plaque Erosion by Intravascular Optical Coherence Tomography,” J. Am. Coll. Cardiol. 63(12_S) (2014)
20. H. Jia, H. Dauerman, C. Toma, H. Samady, S. Lee, R. Vergallo, S. Hu. J. Tian, T. Soeda, Z. Wang, H.Lee, I. McNulty, B. Yu, S. Uemura and I.K. Jang "Management and Clinical Outcome of Patients with Acute Coronary Syndrome Caused by Plaque Rupture and Plaque Erosion: an Intravascular Optical Coherence Tomography Study," J. Am. Coll. Cardiol. 63, 12_S (2014).
21. Z. Wang, G. Linderman, H.G. Bezerra, M.A. Costa, D.L. Wilson and A.M. Rollins, “Optimum Stent Detection in Intravascular OCT: A 3-D Approach,” in SPIE Photonics West, San Francisco (2013). Oral presentation
22. G. Linderman, Z. Wang, H.G. Bezerra, M.A. Costa, D.L. Wilson and A.M. Rollins, “Three Dimensional Calcified Plaque segmentation of Intravascular Optical Coherence Tomography using Interactive Graph Cuts,” in SPIE Photonics West, San Francisco (2013). Oral presentation
23. D.L. Wilson, Z. Wang, H. Lu, H.G. Bezerra, M.A. Costa and A.M. Rollins, “Assessments from Intravascular OCT,” in SPIE Photonics West, San Francisco (2013). Oral presentation
24. Z. Wang, M.W. Jenkins, H.G. Bezerra, M.A. Costa, D.L. Wilson and A.M. Rollins, "Single-shot Stent Segmentation in Intravascular OCT Pullbacks," in Biomedical Optics (BIOMED) - OSA, Miami (2012). Oral presentation
25. Z. Wang, D. Chamié, H.G. Bezerra, D.L. Wilson, M.A. Costa and A.M. Rollins, "Three Dimensional Volumetric Quantification of Fibrous Caps Using Intravascular Optical Coherence Tomography," in SPIE Photonics West, San Francisco (2012). Oral presentation
26. G. Linderman, Z. Wang, H.G. Bezerra, M.A. Costa, and A.M. Rollins, “OCTivat: Optical Coherence Tomography Image Visualization and Analysis Toolkit,”, Biomedical Engineering Society (BMES), (2011), Oral presentation
27. Z. Wang, S. Tahara, T. Morooka, H.G. Bezerra, M.A. Costa and A.M. Rollins, "Quantification of Macrophages in ApoE Deficient Mouse Aorta by Optical Coherence Tomography," SPIE/OSA European conferences on Biomedical Optics (2011) Oral presentation
28. Z. Wang, H. Kyono, H. G. Bezerra, D.L. Wilson, M.A. Costa and A.M. Rollins, "Automatic Segmentation of Intravascular Optical Coherence Tomography Images for Facilitating Quantitative Diagnosis of Atherosclerosis," Proc. SPIE 7889-7822 (2011)
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