高璐 副教授（硕士生导师）

联系方式
通讯地址：成都市人民南路三段17# 四川大学华西药学院，610041
电子邮箱E-mail: lugao@scu.edu.cn

教育背景及工作经历
2005-2009 四川大学华西药学院，本科。
2009-2014 四川大学华西药学院药物化学专业硕博连读，师从宋振雷教授。
2014-2016 四川大学华西药学院，讲师。
2016-至今 四川大学华西药学院，副教授。

科研项目
1、国家自然科学基金青年基金：“手性硅烷及手性硅替代活性分子的合成及应用研究” 2016-2018，主持
2、四川大学青年教师启动基金：“手性有机硅烷的合成、性能及硅替代药物合成研究” 2015-2016，主持

研究方向
手性硅烷及含硅试剂的合成及应用研究

发表论文
1.Hu J.; Gao, L.*; Song, Z. L.* Study on Regio- and Diastereoselective Epoxide Opening/Halogenation of Geminal Bis(silyl) 2,3-Epoxy Alcohols. Chinese Journal of Synthetic Chemistry, 2017, 25(4): 277-281
2.Lin, X. L.; Gan, Z. B.; Lu, J.; Su, Z. S.; Hu, C. W.; Zhang, Y. B.; Wu, Y.; Gao, L.*; Song, Z. L.* Visible light-promoted radical cyclization of silicon-tethered alkyl iodide and phenyl alkyne. An efficient approach to synthesize benzosilolines. Chem. Commun. 2016, 52, (36), 6189-6192.
3.Huang, Z. G.; Gao, L.*; Song, Z. L.* Asymmetric alkylation or silylation of (S)-(?)-diphenylprolinol-derived α-silyl amide to synthesize optically pure α-monosilyl or bis(silyl) amides. Tetrahedron Lett. 2016, 57, (26), 2861-2864.
4.Xu, Y. J.; Yin, Z. P.; Lin, X. L.; Gan, Z. B.; He, Y. Y.; Gao, L.*; Song, Z. L.* 1,4-Hydroiodination of Dienyl Alcohols with TMSI To Form Homoallylic Alcohols Containing a Multisubstituted Z-Alkene and Application to Prins Cyclization. Org. Lett. 2015, 17, (8), 1846-1849.
5.Yin, Z. P.; Liu, Z. J.; Huang, Z. G.; Chu, Y.; Chu, Z. W.; Hu, J.; Gao, L.*; Song, Z. L. * Synthesis of Functionalized γ-Lactone via Sakurai exo-Cyclization/Rearrangement of 3,3-Bis(silyl) Enol Ester with a Tethered Acetal. Org. Lett. 2015, 17, (6), 1553-1556.
6.Li, L. J.; Zhang, Y. B.; Gao, L.*; Song, Z. L.* Recent advances in C–Si bond activation via a direct transition metal insertion. Tetrahedron Lett. 2015, 56, (12), 1466-1473.
7.Wu, Y.; Gao, L.*; Song, Z. L.* Recent Advances in Silicon-stereogenic Chiral Organosilanes. Chemistry 2015, 78, 676-680.
8.Gao, L.; Lu, J.; Song, Z. L.;* Lin, X. L.; Xu, Y. J.; Yin, Z. P. [1,5]-Brook Rearrangement: An Overlooked but Valuable Silyl Migration to Synthesize Configurationally Defined Vinylsilane. The Unique Steric and Electronic Effects of Geminal Bis(silane) Chem. Commun. 2013, 49, 8961-8963.
9.Gao, L.; Lu, J.; Song, Z. L.* Recent efforts to construct the B-ring of bryostatins Chem. Commun. 2013, 49, 10211-10220.
10.Gao, L.; Zhang, Y. B.; Song, Z. L.* Exploration of Versatile Geminal Bis(silane) Chemistry Synlett 2013, 24, 139-144.

11.Gao, L.; Lin, X. L.; Lei, J.; Song, Z. L.;* Lin, Z. Bissilyl Enal: A Useful Linchpin for Synthesis of Functionalized Vinylsilane Species by Anion Relay Chemistry Org. Lett. 2012, 14(1), 158-161.



编辑：四川大学华西药学院