王慧婧 特聘副研究员

单位：四川大学华西药学院 药物化学系
通讯地址：成都市人民南路三段17号四川大学华西药学院610041
E-mail:wanghuijing@scu.edu.cn，hjwang0313@163.com
教育与工作经历：
2008.09-2012.06 四川大学华西药学院 理学学士
2012.09-2017.06 重庆大学创新药物研究中心 工学博士（导师：秦勇教授）
2017.09-2019.12 美国加州大学圣地亚哥分校（UCSD） 博士后（导师：Dionicio Siegel教授）
2020.04-至今 四川大学华西药学院药物化学系，特聘副研究员
研究方向
1.具有重要生理活性的天然产物全合成
2.活性小分子的结构修饰、构效关系研究及先导化合物的发现
科研项目
2020-2023 四川大学引进人才科研启动经费资助项目
发表论文
1.Huijing Wang, Qiuyan Dong, Qinxia Xie, Pei Tang*. Asymmetric synthesis of ABC tricyclic systems in Daphniphyllum alkaloid. Chin. Chem. Lett. 2020, 31, 685-688.
2.Huijing Wang, Matthew J. Kolar, Tina Chang, Jose? Rizo, Srihari Konduri, Clare McNerlin, Alan Saghatelian, and Dionicio Siegel*. Stereochemistry of Linoleic Acid Esters of Hydroxy Linoleic Acids. Org. Lett. 2019, 21, 8080?8084.
3.Huijing Wang, Tina Chang, Srihari Konduri, Jianbo Huang, Alan Saghatelian, Dionicio Siegel*. Synthesis of chemically edited derivatives of the endogenous regulator of inflammation 9-PAHSA. J. Antibiot. 2019, 72 (6), 498? 506.
4.Yi Luo, Lingmei Guo, Xinling Yu, Haosheng Ding, Huijing Wang*, and Yong Wu*. Cp*IrIII-Catalyzed [3+2] Annulations of N-Aryl-2- aminopyrimidines with Sulfoxonium Ylides to Access 2-Alkyl Indoles Through C–H Bond Activation. Eur. J. Org. Chem. 2019, 3203–3207.
5.Yan-zhao Liu, Yao Hu, Guang-hui Lv, Rui-fang Nie, Yao Peng, Chen Zhang, Song-yang Lv, Li Hai, Hui-jing Wang*, and Yong Wu*. Synthesis of 1,2-Benzothiazines via C?H Activation/Cyclization in a Recyclable, Mild System. ACS Sustainable Chem. Eng. 2019, 7, 13425?13429.
6.Huijing Wang, Pei Tang, Qilong Zhou, Dan Zhang*, Zhitao Chen, Hongxiu Huang, Yong Qin*. One-Pot Synthesis of Multisubstituted Butyrolactonimidates: Total Synthesis of (-)-Nephrosteranic Acid, J. Org. Chem. 2015, 80, 2494-2505. (Featured Article).
7.Hongxiu Huang, Huijing Wang (co-first author), Ling Tan, Shuqing Wang, Pei Tang, Hao Song*, Xiao-Yu Liu, Dan Zhang, Yong Qin*. Asymmetric Michael Addition Induced by (R)-tert-Butanesulfinamide and Synthesis of Chiral Pyrazolidinone Derivatives, J. Org. Chem. 2016, 81, 10506-10516.
8.Huijing Wang, Dan Zhang*, Fusheng Wang, Yi Wu, Hao Song. Synthesis and Anticholinesterase Activity of (-)-Physostigmine, Analogues with Modifications at C3a and C5, Chem. Res. Chin. Univ. 2013, 29, 888-893.
9.Lingmei Guo, Baolan Tang, Ruifang Nie, Yanzhao Liu, Shan Lv, Huijing Wang, Li Guo, Li Hai*, and Yong Wu*. C–H alkenylation/cyclization and sulfamidation of 2-phenylisatogens using N-oxide as a directing group. Chem.Commun. 2019, 55, 10623?10626.
10.Matthew J. Kolar, Srihari Konduri, Tina Chang, Huijing Wang, Clare McNerlin, Lena Ohlsson, Magnus Ha?rro?d, Dionicio Siegel*, and Alan Saghatelian*. Linoleic acid esters of hydroxy linoleic acids are anti-inflammatory lipids found in plants and mammals. J. Biol. Chem. 2019, 294 (27), 10698?10707.
11.Fei Xue, Tao Xiao, Huijing Wang, Dan Zhang*, Hao Song, Yong Qin*. Synthesis of chiral trans-fused 2-methyl-5-hydroxyldecahydroquinoline, Tetrahedron, 2015, 71, 5640-5643.
12.Xiaobei Wang, Dongliang Xia, Wenfang Qin, Ruijie Zhou, Xiaohan Zhou, Qilong Zhou, Wentao Liu, Xiang Dai, Huijing Wang, Shuqing Wang, Ling Tan, Dan Zhang, Hao Song, Xiao-Yu Liu, Yong Qin*. A radical cascade enabling collective syntheses of divergent natural products, Chem 2017, 2, 803-816.
13.Qilong Zhou, Huijing Wang, Pei Tang, Hao Song, Yong Qin*. Total Synthesis of Lignan Lactone (-)-Hinokinin, Nat. Prod. Bioprospect. 2015, 5, 255-261.



编辑：四川大学华西药学院