个人简介
Gaojian Chen, Professor
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Center for Soft Condensed Matter Physics and Interdisciplinary Research
Soochow University
1 Shizi Street, Suzhou 215006, China
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Email:gchen@suda.edu.cn


Researcher ID:http://www.researcherid.com/rid/C-2802-2008




University of Warwick, PhD inChemistrySep.2004 - Oct. 2007

Soochow University, B.S. inChemistrySep.1996 - July 2000


Jul. 2015 – presentSoochow University,Professor

Mar. 2010 – Mar. 2012Chinese University of Hong Kong,Research Associate
<span font-size:10pt;= style=box-sizing: border-box; padding: 0px; margin: 0px; border: 0px;>Dec. 2007 –Nov. 2009University of New South Wales, Research Associate




先后在苏州大学朱秀林教授和英国华威（Warwick）大学DavidHaddleton教授课题组获得硕士和博士学位，在澳大利亚新南威尔士大学Martina Stenzel教授和香港中文大学吴奇教授课题组开展博士后研究。主要工作涉及生物大分子合成方法学和含糖聚合物材料制备及应用研究。目前已在Macromolecules, Chem. Commun.，Soft Matter, Polym. Chem.等杂志上发表论文70多篇，H因子24，受邀在Wiley及Springer出版的专著中撰写多个章节，并多次受邀在ACS，RSC等国际会议作特邀口头报告。



研究领域
研究方向主要围绕生物大分子的合成与含糖聚合物材料的制备和应用。
包括：
生物大分子合成方法学
绿色可见光控制聚合
含糖材料制备及特异性识别
识别和靶向癌细胞的功能材料
识别和调控细菌/细胞的功能高分子




基本信息
陈高健
职称： 研究员
院部/部门： 物理科学与技术学院
学历：
学位：
毕业学校：
毕业专业：


联系方式
通讯地址：
邮政编码：
电子邮箱： gchen@suda.edu.cn
联系电话： +86-
传真号码：
办公地点： 独墅湖校区701-1121




Copyright ? 2011-2014苏州大学版权所有苏州大学信息化建设与管理中心技术支持




科学研究




科研团队



Copyright ? 2011-2014苏州大学版权所有苏州大学信息化建设与管理中心技术支持




论文
2018
Peng, L., Luo, Y., Zheng, Y., Zhang, W., & Chen, G. (2018). Sunlight-Induced RAFT Synthesis of Multifaceted Glycopolymers with Surface Anchoring, In Situ AgNP Formation, and Antibacterial Properties.ACS Applied Nano Materials, 1(5), 2219–2226. http://doi.org/10.1021/acsanm.8b00286
Wen, M., Liu, M., Xue, W., Yang, K., Chen, G., & Zhang, W. (2018). Simple and Green Strategy for the Synthesis of “Pathogen-Mimetic” Glycoadjuvant@AuNPs by Combination of Photoinduced RAFT and Bioinspired Dopamine Chemistry.ACS Macro Letters, 7(1), 70–74. http://doi.org/10.1021/acsmacrolett.7b00837

2017
Weng, Y., Li, Z., Peng, L., Zhang, W., & Chen, G. (2017). Fabrication of carbon quantum dots with nano-defined position and pattern in one stepvia sugar-electron-beam writing.Nanoscale, 9(48), 19263–19270. http://doi.org/10.1039/C7NR07892G
Hu, X., Gao, J., Luo, Y., Wei, T., Dong, Y., Chen, G., & Chen, H. (2017). One-Pot Multicomponent Synthesis of Glycopolymers through aCombination of Host-Guest Interaction, Thiol-ene, and Copper-Catalyzed Click Reaction in Water.Macromolecular Rapid Communications, 38(20), **. http://doi.org/10.1002/marc.
Peng, L., Zhou, S., Yang, B., Bao, M., Chen, G., & Zhang, X. (2017). Chemically Modified Surface Having a Dual-Structured HierarchicalTopography for Controlled Cell Growth.ACS Applied Materials & Interfaces, 9(28), 24339–24347. http://doi.org/10.1021/acsami.7b06197
Xue, W., Wang, J., Wen,M., Chen, G., & Zhang, W. (2017). Integration of CuAAC Polymerization andControlled Radical Polymerization into Electron Transfer Mediated“Click-Radical” Concurrent Polymerization.Macromolecular RapidCommunications,38(6), **.http://doi.org/10.1002/marc.
Liu, Q., Lyu, Z., Yu,Y., Zhao, Z., Hu, S., Yuan, L., Chen, G.,Chen, H. (2017). Synthetic Glycopolymers forHighly Efficient Differentiation of Embryonic Stem Cells into Neurons: Lipo- orNot?ACS Applied Materials & Interfaces,9(13), 11518–11527.http://doi.org/10.1021/acsami.7b01397
Peng, L., Li, Z., Li,X., Xue, H., Zhang, W., & Chen, G. (2017). Integrating Sugar and Dopamineinto One Polymer: Controlled Synthesis and Robust Surface Modification.MacromolecularRapid Communications,38(3), **.http://doi.org/10.1002/marc.
Xue, H., Peng, L.,Dong, Y., Zheng, Y., Luan, Y., Hu, X., Chen, G.,Chen, H. (2017). Synthesis ofstar-glycopolymers by Cu(0)-mediated radical polymerisation in the absence andpresence of oxygen.RSC Adv.,7(14), 8484–8490.http://doi.org/10.1039/C6RA28763H

2016

Liu, Q., Xue, H., Gao,J., Cao, L., Chen, G., & Chen, H. (2016). Synthesis of lipo-glycopolymersfor cell surface engineering.Polym. Chem.,7(47), 7287–7294.http://doi.org/10.1039/C6PY01788F
Wang, J., Rivero, M.,Mu?oz Bonilla, A., Sanchez-Marcos, J., Xue, W., Chen, G., … Zhu, X. (2016).Natural RAFT Polymerization: Recyclable-Catalyst-Aided, Opened-to-Air, andSunlight-Photolyzed RAFT Polymerizations.ACS Macro Letters,5,1278–1282. http://doi.org/10.1021/acsmacrolett.6b00818
Li, Z., Zhang, P., Lu,W., Peng, L., Zhao, Y., & Chen, G. (2016). Ratiometric Fluorescent pHProbes Based on Glycopolymers.Macromolecular Rapid Communications,37(18),1513–1519. http://doi.org/10.1002/marc.
Xue, L., Xiong, X.,Chen, K., Luan, Y., Chen, G., & Chen, H. (2016). Modular synthesis ofglycopolymers with well-defined sugar units in the side chain via Ugi reactionand click chemistry: hetero vs. homo.Polym. Chem.,7(25),4263–4271. http://doi.org/10.1039/C6PY00734A
Cao, L., Shi, X., Cui,Y., Yang, W., Chen, G., Yuan, L., & Chen, H. (2016). Protein–polymerconjugates prepared via host–guest interactions: effects of the conjugationsite, polymer type and molecular weight on protein activity.Polym. Chem.,7(32), 5139–5146. http://doi.org/10.1039/C6PY00882H
Wang, J., Wang, X.,Xue, W., Chen, G., Zhang, W., & Zhu, X. (2016). Initiator andPhotocatalyst-Free Visible Light Induced One-Pot Reaction: Concurrent RAFTPolymerization and CuAAC Click Reaction.Macromolecular Rapid Communications,37(9), 799–804. http://doi.org/10.1002/marc.
Chen, K., Bao, M.,Mu?oz Bonilla, A., Zhang, W., & Chen, G. (2016). A biomimicking andelectrostatic self-assembly strategy for the preparation of glycopolymerdecorated photoactive nanoparticles.Polym. Chem.,7(14),2565–2572. http://doi.org/10.1039/C6PY00129G
Li, X., Zhang, W.,& Chen, G. (2016). Synthesis of Non-spherical Glycopolymer-DecoratedNanoparticles: Combing Thiol-ene with Catecholic Chemistry (Vol. 1367, pp.149–155). Springer. http://doi.org/10.1007/978-1-4939-3130-9_12

2015

Wang, S., Yuan, F.,Chen, K., Chen, G., Tu, K., Wang, H., & Wang, L.-Q. (2015). Synthesis ofHemoglobin Conjugated Polymeric Micelle: A ZnPc Carrier with OxygenSelf-Compensating Ability for Photodynamic Therapy.Biomacromolecules,16(9),2693–2700. http://doi.org/10.1021/acs.biomac.5b00571
Shi, X., Zhan, W.,Chen, G., Yu, Q., Liu, Q., Du, H., … Chen, H. (2015). Regulation of ProteinBinding Capability of Surfaces via Host–Guest Interactions: Effects ofLocalized and Average Ligand Density.Langmuir,31(22),6172–6178. http://doi.org/10.1021/acs.langmuir.5b01380
Yuan, F., Wang, S., Lu,W., Chen, G., Tu, K., Jiang, H., & Wang, L.-Q. (2015). Facile preparationof cancer-specific polyelectrolyte nanogels from natural and synthetic sugar polymers.J. Mater. Chem. B,3(22), 4546–4554.http://doi.org/10.1039/C5TB00539F
Li, B., Wang, M., Chen,K., Cheng, Z., Chen, G., & Zhang, Z. (2015). Synthesis of BiofunctionalJanus Particles.Macromolecular Rapid Communications,36(12),1200–1204. http://doi.org/10.1002/marc.
Li, X., & Chen, G.(2015). Glycopolymer-based nanoparticles: synthesis and application.Polym.Chem.,6(9), 1417–1430. http://doi.org/10.1039/C4PY01740D
Xue, L., Lyu, Z., Luan,Y., Xiong, X., Pan, J., Chen, G., & Chen, H. (2015). Efficient cancer cellcapturing SiNWAs prepared via surface-initiated SET-LRP and click chemistry.Polym.Chem.,6(19), 3708–3715. http://doi.org/10.1039/C5PY00247H

2014

Li, X., Bao, M., Weng, Y., Yang, K., Zhang, W.*, & Chen, G.* (2014).Glycopolymer-coated iron oxide nanoparticles: shape-controlled synthesis andcellular uptake.Journal of Materials Chemistry B,2(34), 5569.doi:10.1039/C4TB00852A
Li, X., Wang, L., Chen, G.*, Haddleton, D. M., & Chen, H.* (2014).Visible light induced fast synthesis of protein-polymer conjugates:controllable polymerization and protein activity.Chemical Communications,50(49), 6506–8. doi:10.1039/c4cc02277g
Lu, J., Fu, C., Wang, S., Tao, L.*, Yan, L.*, Haddleton, D. M., Chen,G.*,Wei, Y. (2014). From Polymer Sequence Control to Protein Recognition:Synthesis, Self-Assembly and Lectin Binding.Macromolecules,47(14),4676–4683. doi:10.1021/ma500664u
Lu, J., Zhang, W., Richards, S., Gibson, M. I., & Chen, G.* (2014).Glycopolymer-coated gold nanorods synthesised by a one pot copper(0) catalyzedtandem RAFT/click reaction.Polymer Chemistry,5(7), 2326.doi:10.1039/c3py01526b
Lu, J., Zhang, W., Yuan, L., Ma, W., Li, X., Lu, W., Zhao, Y.*,Chen,G.* (2014). One-pot synthesis of glycopolymer-porphyrin conjugate as photosensitizerfor targeted cancer imaging and photodynamic therapy.MacromolecularBioscience,14(3), 340–6. doi:10.1002/mabi.
Lu, W., Ma, W., Lu, J., Li, X., Zhao, Y.*, & Chen, G.* (2014).Microwave-assisted synthesis of glycopolymer-functionalized silvernanoclusters: combining the bioactivity of sugar with the fluorescence andcytotoxicity of silver.Macromolecular Rapid Communications,35(8),827–33. doi:10.1002/marc.
Shi, X., Chen, G.*, Yuan, L., Tang, Z., Liu, W., Zhang, Q.,Haddleton, D.*,Chen,H.* (2014). Integrating a thermoresponsive copolymer with host–guestinteractions for fabricating molecular recognition surfaces.MaterialsHorizons,1(5), 540. doi:10.1039/C4MH00081A
Wang, J., Zhu, H., Chen, G., Hu, Z.*, Weng, Y., Wang, X., & Zhang, W.*(2014). Controlled synthesis and self-assembly of dopamine-containing copolymerfor honeycomb-like porous hybrid particles.Macromolecular RapidCommunications,35(11), 1061–7. doi:10.1002/marc.
Wang, L., Li, J., Zhang, W., Chen, G.*, Zhang, W.*, & Zhu, X. (2014).A novel approach to synthesize polymers for potential photodynamic therapy:from benzenedinitrile to phthalocyanine.Polymer Chemistry,5(8),2872. doi:10.1039/c3py01129a
Xue, L., Lyu, Z., Shi, X., Tang, Z., Chen, G.*, & Chen, H.* (2014).Fast and Green Synthesis of a Smart Glyco-surface via Aqueous Single ElectronTransfer-Living Radical Polymerization.Macromolecular Chemistry and Physics,215(15), 1491–1497. doi:10.1002/macp.
Yuan, F., Wang, S., Chen, G.*, Tu, K., Jiang, H., & Wang, L.* (2014).Novel chitosan-based pH-sensitive and disintegrable polyelectrolyte nanogels.Colloidsand Surfaces. B, Biointerfaces,122, 194–201.doi:10.1016/j.colsurfb.2014.06.042
Chen, G., Yang, J., Lu, G., Liu, P. C., Chen, Q., Xie, Z., & Wu, C.*(2014). One Stone Kills Three Birds: Novel Boron-Containing Vesicles forPotential BNCT, Controlled Drug Release, and Diagnostic Imaging.MolecularPharmaceutics. doi:10.1021/mp400641u
Du, X., Wang, Y., Yuan, L.*, Weng, Y., Chen, G.*, & Hu, Z.* (2014).Guiding the behaviors of human umbilical vein endothelial cells with patternedsilk fibroin films.Colloids and Surfaces. B, Biointerfaces,122,79–84. doi:10.1016/j.colsurfb.2014.06.049
Luo, F., Cheng, Z., Wang, M., Chen, G., & Zhang, Z.* (2014). Synthesisof soft colloids with well-controlled softness.Chemical Communications,50(56), 7535–7. doi:10.1039/c4cc02485k
Liu, J., Li, J., Zhang, Z., Weng, Y., Chen, G., Yuan, B.*, … Ma, Y.*(2014). Encapsulation of Hydrophobic Phthalocyanine with Poly(N-isopropylacrylamide)/LipidComposite Microspheres for Thermo-Responsive Release and Photodynamic Therapy.Materials,7(5), 3481–3493. doi:10.3390/ma**
Wang, Z., Chen, G., Lu, J., Hong, L.*, & Ngai, T.* (2013).Investigation of the factors affecting the carbohydrate–lectin interaction byITC and QCM-D.Colloid and Polymer Science,292(2), 391–398.doi:10.1007/s00396-013-3080-0
Liu, X., Yuan, L., Li, D., Tang, Z., Wang, Y., Chen, G.,Chen,H.*,Brash, J. L.* (2014). Blood compatible materials: state of the art.Journalof Materials Chemistry B,2(35), 5718. doi:10.1039/C4TB00881B
Tan, M., Wang, H., Wang, Y., Chen, G., Yuan, L.*, & Chen, H.* (2014).Recyclable antibacterial material: silicon grafted with 3,6-O-sulfated chitosanand specifically bound by lysozyme.Journal of Materials Chemistry B,2(5),569. doi:10.1039/c3tb21358g

2013
Li, J., Zhang, W., Hu, Z., Jiang, X.-J., Ngai, T., Lo, P.-C.,Zhang,W.,Chen, G.* (2013). Novel phthalocyanine and PEG-methacrylates basedtemperature-responsive polymers for targeted photodynamic therapy.PolymerChemistry,4(3), 782. doi:10.1039/c2py20668d
Shi, X., Chen, G.*, Wang, Y., Yuan, L., Zhang, Q., Haddleton, D. M., &Chen, H.* (2013). Control the wettability ofpoly(n-isopropylacrylamide-co-1-adamantan-1-ylmethyl acrylate) modifiedsurfaces: the more Ada, the bigger impact?Langmuir,29(46), 14188–95.doi:10.1021/la**


2012
Shen, Q., Zhang, J., Zhang, S., Hao, Y., Zhang, W.*, Zhang, W., Chen, G.,Zhang, Z.,Zhu, X.* (2012). Facile one-pot/one-step technique forpreparation of side-chain functionalized polymers: Combination of SET-RAFT polymerizationof azide vinyl monomer and click chemistry.Journal of Polymer Science PartA: Polymer Chemistry,50(6), 1120–1126.
Zhang, W., Chen, G., Hu, Z., Zhang, W., Zhang, Z., & Zhu, X.* (2012).Precisely controlled copper(0)-catalyzed one-pot reaction: Concurrent livingradical polymerization and click chemistry.Journal of Polymer Science PartA: Polymer Chemistry,50(17), 3656–3663.


2011
Huynh, V. T., Chen, G., Souza, P. De, & Stenzel, M. H.* (2011).Thiol-yne and Thiol-ene “Click” Chemistry as a Tool for a Variety of PlatinumDrug Delivery Carriers, from Statistical Copolymers to Crosslinked Micelles.Biomacromolecules,12(5), 1738–51. doi:10.1021/bm200135e
Kumar, J., McDowall, L., Chen, G., & Stenzel, M. H.* (2011). Synthesisof thermo-responsive glycopolymers via copper catalysed azide–alkyne “click”chemistry for inhibition of ricin: the effect of spacer between polymerbackbone and galactose.Polymer Chemistry,2(8), 1879–1886.doi:10.1039/c1py00048a
Pearson, S., Chen, G., & Stenzel, M. H.* (2011). Synthesis ofGlycopolymers. In R. Narain (Ed.),Engineered Carbohydrate-Based Materialsfor Biomedical Applications(pp. 1–118). John Wiley & Sons.doi:10.1002/49.ch1
Tao, L., Chen, G., Zhao, L., Xu, J., Huang, E., Liu, A., … Davis, T. P.* (2011).Protein release from biodegradable polyHPMA-lysozyme conjugates resulting inbioactivity enhancement.Chemistry, an Asian Journal,6(6),1398–404. doi:10.1002/asia.
Wang, J., Yue, Y., Chen, G., & Xia, J.* (2011). Protease-promoted drugdelivery using peptide-functionalized gold nanoparticles.Soft Matter,7(16),7217. doi:10.1039/c1sm05242j
Zhang, W., Zhang, W., Cheng, Z., Zhou, N., Zhu, J., Zhang, Z.,Chen,G.,Zhu, X.* (2011). Synthesis and Aggregation Behaviors of NonlinearMultiresponsive, Multihydrophilic Block Copolymers.Macromolecules,44(9),3366–3373. doi:10.1021/ma200083v


2010
Chen, Y., Chen, G., & Stenzel, M. H.* (2010). Synthesis and LectinRecognition of Glyco Star Polymers Prepared by “Clicking” Thiocarbohydratesonto a Reactive Scaffold.Macromolecules,43(19), 8109–8114.doi:10.1021/ma100919x
Hetzer, M., Chen, G., Barner-Kowollik, C., & Stenzel, M. H.* (2010).Neoglycopolymers based on 4-vinyl-1,2,3-triazole monomers prepared by clickchemistry.Macromolecular Bioscience,10(2), 119–26.doi:10.1002/mabi.
Ting, S., Chen, G., & Stenzel, M. H.* (2010). Synthesis ofglycopolymers and their multivalent recognitions with lectins.PolymerChemistry,1(9), 1392. doi:10.1039/c0py00141d

before 2010
Chen, G., Amajjahe, S., & Stenzel, M. H. (2009). Synthesis ofthiol-linked neoglycopolymers and thermo-responsive glycomicelles as potentialdrug carrier.Chemical Communications, (10), 1198–200.doi:10.1039/b900215d
Chen, G., Kumar, J., Gregory, A., & Stenzel, M. H. (2009). Efficientsynthesis of dendrimers via a thiol-yne and esterification process and theirpotential application in the delivery of platinum anti-cancer drugs.ChemicalCommunications,12(41), 6291–3. doi:10.1039/b910340f
Chen, G., Tao, L., Mantovani, G., Geng, J., Nystr?m, D., & Haddleton,D. M. (2007). A Modular Click Approach to Glycosylated Polymeric Beads: Design,Synthesis and Preliminary Lectin Recognition Studies.Macromolecules,40(21),7513–7520. doi:10.1021/ma071362v
Chen, G., Tao, L., Mantovani, G., Ladmiral, V., Burt, D. P., Macpherson,J. V., & Haddleton, D. M. (2007). Synthesis of azide/alkyne-terminalpolymers and application for surface functionalisation through a [2 + 3]Huisgen cycloaddition process,??click chemistry?Soft Matter,3(6),732. doi:10.1039/b618325e
Chen, G., Wright, P. M., Geng, J., Mantovani, G., & Haddleton, D. M.(2008). Tunable thermoresponsive water-dispersed multiwalled carbon nanotubes.ChemicalCommunications, (9), 1097–9. doi:10.1039/b718112d
Chen, G., Zhu, X., Zhu, J., & Cheng, Z. (2004). Plasma-InitiatedControlled/Living Radical Polymerization of Methyl Methacrylate in the Presenceof 2-Cyanoprop-2-yl 1-dithionaphthalate(CPDN).Macromolecular RapidCommunications,25(7), 818–824. doi:10.1002/marc.
Geng, J., Lindqvist, J., Mantovani, G., Chen, G., Sayers, C. T., Clarkson,G. J., & Haddleton, D. M. (2007). Well-Defined Poly(N-glycosyl1,2,3-triazole) Multivalent Ligands: Design, Synthesis and Lectin BindingStudies.QSAR & Combinatorial Science,26(11-12), 1220–1228.doi:10.1002/qsar.
Geng, J., Mantovani, G., Tao, L., Nicolas, J., Chen, G., Wallis, R., …Haddleton, D. M. (2007). Site-directed conjugation of “clicked” glycopolymersto form glycoprotein mimics: binding to mammalian lectin and induction ofimmunological function.Journal of the American Chemical Society,129(49),15156–63. doi:10.1021/ja072999x
Gu, W., Chen, G., & Stenzel, M. H. (2009). Synthesis ofglyco-microspheres via a thiol-ene coupling reaction.Journal of PolymerScience Part A: Polymer Chemistry,47(20), 5550–5556.doi:10.1002/pola.23615
McDowall, L., Chen, G., & Stenzel, M. H. (2008). Synthesis ofSeven-Arm Poly(vinyl pyrrolidone) Star Polymers with Lysozyme Core Prepared byMADIX/RAFT Polymerization.Macromolecular Rapid Communications,29(20),1666–1671. doi:10.1002/marc.
Tao, L., Chen, G., Mantovani, G., York, S., & Haddleton, D. M. (2006).Modification of multi-wall carbon nanotube surfaces with poly(amidoamine)dendrons: synthesis and metal templating.Chemical Communications, (47),4949–51. doi:10.1039/b609065f
Tao, L., Geng, J., Chen, G., Xu, Y., Ladmiral, V., Mantovani, G., &Haddleton, D. M. (2007). Bioconjugation of biotinylated PAMAM dendrons toavidin.Chemical Communications, (33), 3441–3. doi:10.1039/b709080c
Withey, A. B. J., Chen, G., Nguyen, T. L. U., & Stenzel, M. H. (2009).Macromolecular cobalt carbonyl complexes encapsulated in a click-cross-linkedmicelle structure as a nanoparticle to deliver cobalt pharmaceuticals.Biomacromolecules,10(12), 3215–26. doi:10.1021/bm901050x
Xu, W., Zhu, X., Cheng, Z., Chen, G., & Zhu, J. (2005). Polymerizationof styrene with tetramethylthiuram disulfide as an initiator in the presence of2,2,6,6-tetramethyl-1-piperidinyloxy.Journal of Polymer Science Part A:Polymer Chemistry,43(3), 543–551. doi:10.1002/pola.20533



荣誉奖励




Copyright ? 2011-2014苏州大学版权所有苏州大学信息化建设与管理中心技术支持




开授课程
本科教学
《生命中的甜蜜化学》
《材料化学 Materials Chemistry》
研究生教学
《软物质物理》
《软物质前沿》



招生信息
本课题组现招收有志于科研工作的研究生及博士后。招生方向包括高分子化学与物理，材料化学与物理等，欢迎具有物理，化学、或材料背景的同学报考。



Copyright ? 2011-2014苏州大学版权所有苏州大学信息化建设与管理中心技术支持