个人资料
直属机构：医学部公共卫生学院
联系电话：**
性别：男
电子邮箱：tchen@suda.edu.cn
专业技术职务：
办公地址：402-2423
毕业院校：中国科学院动物研究所
通讯地址：
学位：博士
邮编：
学历：博士
传真：


教育经历
教育经历：博士研究生,2002.08.01 00:00:00-2005.09.01 00:00:00,中科院动物所,博士



工作经历
工作经历：2010-2012,英国纽卡斯尔大学,研究人员
2007-2009,英国伯明翰大学,研究人员




个人简介
个人简介：

社会职务
社会职务：


研究领域
研究领域：１．环境化学物（PM2.5，BaP,三氯乙烯）的心脏发育毒性
２．环境化学物致癌的表观遗传毒性机制



开授课程
开授课程：1、卫生毒理学双语及全英文,本科生
2、高级毒理学,研究生

课程教学：


科研项目
科研项目：1、AHR调控RNA m6A甲基化介导大气PM2.5心脏发育毒性的机制研究,2020-,陈涛,国家自然科学基金,**
2、白藜芦醇通过AhR和Rspo2/Wnt通路对大气PM2.5心脏发育毒性的保护机制研究,2018-,陈涛,国家自然科学基金,**




论文
论文：1、Huang Y, Jiang B, Xia Y, Wang J, Ji C, Tong J, Chen?T*, Jiang Y*. Downregulation of miR-133a contributes to the cardiac developmental toxicity of trichloroethylene in zebrafish. Chemosphere. 2020. 251:126610
2、Ren F, Ji C, Huang YJ, Aniagu S, Tong J, Jiang Y*, Chen?T*, AHR-mediated ROS production contributes to the cardiac developmental toxicity of PM2.5 in zebrafish embryos. Sci Total Environ. 2020 Jun 1;719:135097.
3、Jin H, Ji C, Ren F, Aniagu S, Tong J, Jiang Y*, Chen?T*. AHR-mediated oxidative stress contributes to the cardiac developmental toxicity of trichloroethylene in zebrafish embryos. J Hazard Mater. 2020 Mar 5;385:121521.
4、Ren F, Wang J, Aniagu S, Li J, Jiang Y*, Chen?T*，Effects of Trichloroethylene on the Expression of Long Intergenic Noncoding RNAs in B6C3F1 Mouse Liver. Chem Res Toxicol. 2020 Jan 27.
5、Jiang Y, Li J, Ren F, Ji C, Aniagu S, Chen?T*.PM2.5-induced extensive DNA methylation changes in the heart of zebrafish embryos and the protective effect of folic acid, Environ Pollut. 2019 Dec;255(Pt 3):113331.
6、Jiang Y, Zhou Z, Fei R, Zhou X, Wang J, Tao Y, Li J*, Chen?T*. Role of miR-182-5p overexpression in trichloroethylene-induced abnormal cell cycle functions in human HepG2 cells. J Toxicol Environ Health A. 2019;82(16):920-927.
7、Wang J, Yu XF, OUYang N, Luo Q, Tong J, Chen?T*, Li J*. Role of DNA methylation regulation of miR-130b expression in human lung cancer using bioinformatics analysis. J Toxicol Environ Health A. 2019;82(17):935-943.
8、Wang J, Yu XF, Ouyang N, Zhao S, Yao H, Guan X, Tong J, Chen?T*, Li JX*. MicroRNA and mRNA Interaction Network Regulates the Malignant Transformation of Human Bronchial Epithelial Cells Induced by Cigarette Smoke. Front Oncol. 2019 Oct 9;9:1029
9、Chen T, Jin H, Wang H, Yao Y, Aniagu S, Tong J,?Jiang Y*. Aryl hydrocarbon receptor mediates the cardiac developmental toxicity of EOM from PM2.5?in P19 embryonic carcinoma cells. Chemosphere. 2019 Feb; 216:372-378.
10、Wang J, Yu XF, OUYang N, Luo QL, Zhao SY, Guan XF,?Chen T*, Li JX*. Multi-platform analysis of methylation-regulated genes in human lung adenocarcinoma. J Toxicol Environ Health A. 2019 Jan 9:1-9.
11、Jiang Y, Chen JH, Yue C, Zhang H, Tong J, Li JX*, Chen T*. The role of miR-182-5p in hepatocarcinogenesis of trichloroethylene in mice. Toxicol Sci. 2016 Dec
12、Zhang H, Yao YG, Chen Y, Yue C, Chen JH, Jiang Y*, Chen T*. Crosstalk between AhR and wnt/β-catenin signal pathwaysin the cardiac developmental toxicity of PM2.5 in zebrafish embryos. Toxicology 2016 May
13、Jiang Y, Wang D, Zhang G, Wang G, Tong J*,?Chen T*. Disruption of cardiogenesis in human embryonic stem cells exposed to trichloroethylene. Environ Toxicol. 2015 Apr 6
14、Chen T, Middleton FK, Falcon S, Reaper PM, Pollard JR, Curtin NJ. Development of pharmacodynamic biomarkers for?ATR?inhibitors. Mol Oncol. 2014 Oct 13.?
15、Jiang Y, Chen JH, Tong J, Chen T*. Trichloroethylene-induced gene expression and DNA methylation changes in B6C3F1 mouse liver. Plos One. 2014 Dec 30
16、Chen T, Stephens P, Middleton F, Curtin NJ. Targeting the S and G2 Checkpoint. Drug Discov Today. 2011 Dec 14.
17、Chen T, Williams T, Mally A, Hamberger C, Mirbahai L, Hickling K, Chipman JK*. Gene expression and epigenetic changes by furan in rat liver. Toxicology. 2011
18、Chen T, Mally A, Ozden S, Chipman JK. Low Doses of the Carcinogen Furan Alter Cell Cycle and Apoptosis Gene Expression in Rat Liver Independent of DNA Methylation. Environ Health Perspect. 2010 Nov;118(11):1597-602.




科技成果
软件著作 软件著作：1、Jiang Y, Dai YF, Chen T, Advances in Molecular Toxicology (Chapeter 2 Advances in TCE Toxicology)， Volume 11, Pages 51-79,2017,ELSIVER

专利 专利：1、Method for measuring ATR inhibition mediated increases in DNA damage, ** B2,美国发明专利




荣誉及奖励
荣誉及奖励：



招生信息
招生信息： 招生信息1：