王大勇
教授 医学院
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办公地点：丁家桥校区综合楼406室 电子邮箱：dayongw@seu.edu.cn
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研究方向



研究方向：


模式生物病理与毒理学研究：
（1）感染与免疫。
（2）纳米毒理学。
（3）微重力生物学。


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荣誉奖励






学术成果



科研成果：

[1] 袭著革，李君文，张英鸽，杨旭，王大勇，廖明阳，林治卿，邱志刚，杨丹凤，林本成，陈照立，张伟：微纳尺度粒子对健康影响评价的关键技术研究，天津市科技进步奖（一等奖），2013.
[2] 浦跃朴，刘松琴，王大勇，唐萌，尹立红，梁戈玉，武秋立，卫伟，刘冉，张小强，张婷，张娟，薛玉英，李晓波：纳米材料毒理学评价及环境医学应用的基础研究，教育部自然科学奖（一等奖），2015.
[3] 袭著革、王大勇等，环境微纳米颗粒毒理学效应的基础研究与应用，环境保护部环境保护科学技术奖（三等奖），2015。

专著：

[1] 王大勇，“模式生物毒理学”，东南大学出版社，2013，ISBN 978-7-5641-4080-9.
[2] Dayong Wang, Nanotoxicology in Caenorhabditis elegans.Springer Nature Singapore Pte Ltd., 2018, ISBN:978-981-13-0232-9.

近期发表学术论文：

Year2018

[1] Mingxia Ren, Li Zhao, Xuecheng Ding,Natalia Krasteva, Qi Rui, Dayong Wang. Developmentalbasis for intestinal barrier against the toxicity of graphene oxide. Particle and Fibre Toxicology, 2018,15: 26.
[2] Guosheng Xiao, He Chen, Natalia Krasteva,Qizhan Liu, Dayong Wang.Identification of interneuronsrequired for the aversive response of Caenorhabditiselegans to graphene oxide.J.Nanobiotechnol. 2018, 16: 45.
[3] Xuecheng Ding, Qi Rui, Yunli Zhao, HuiminShao, Yiping Yin, Qiuli Wu, Dayong Wang.Toxicity of graphene oxide in nematodes with deficit in epidermal barriercaused by RNA interference knockdown of unc-52.Environ. Sci. Technol. Lett. 2018,doi: 10.1021/acs.estlett.8b00473.
[4] Huimin Shao, Zhongyu Han, Natalia Krasteva,Dayong Wang. Identification of signalingcascade in the insulin signaling pathway in response to nanopolystyrene particles. Nanotoxicology 2018, doi: 10.1080/**.2018.**.
[5] Yonglin Yu, Lingtong Zhi, Qiuli Wu, LinaJing, Dayong Wang. NPR-9 regulatesinnate immune response in Caenorhabditiselegans by antagonizing activity of AIB interneurons. Cellular & Molecular Immunology 2018, 15: 27-37.

Year2017

[1] Lingtong Zhi, Man Qu, Mingxia Ren, Li Zhao, YunhuiLi, Dayong Wang. Graphene oxide induces canonical Wnt/β-catenin signaling-dependent toxicityin Caenorhabditis elegans. Carbon, 2017, 113: 122-131.
[2] Man Qu, Yunhui Li, Qiuli Wu, Yankai Xia, Dayong Wang. Neuronal ERK signaling in response to graphene oxide innematode Caenorhabditis elegans. Nanotoxicology, 2017, 11(4): 520-533.
[3] Mingxia Ren, Li Zhao, Xiao Lv, Dayong Wang. Antimicrobial proteins in the response to graphene oxidein Caenorhabditis elegans. Nanotoxicology, 2017, 11(4): 578-590.
[4] Li Zhao, Hanxiao Wan, Qizhan Liu, Dayong Wang.Multi-walled carbon nanotubes-induced alterations in microRNA let-7 and itstargets activate a protection mechanism by conferring a developmental timingcontrol. Particle and Fibre Toxicology, 2017, 14: 27.
[5] Lingtong Zhi, Yonglin Yu, Xueying Li, Daoyong Wang, Dayong Wang. Molecular control of innate immune response to Pseudomonas aeruginosa infection by intestinal let-7 in Caenorhabditis elegans. PLoS Pathogens, 2017, 13(1): e**.
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