1、针对基因组测序数据进行致病基因及其突变的筛选与分析；
2、针对转录组测序数据进行癌症特异基因的差异表达分析，预测新转录本；
二 大数据分析与数据挖掘
1．生物大数据分析的算法设计；
2．生物医学网络应用程序与数据库的开发；
个人简介
宋晓峰 博士，南京航空航天大学，自动化学院生物医学工程系，教授，博士生指导教师，江苏省生物医学工程学会理事，2013年度江苏省“六大人才高峰”人才项目培养对象。主要研究领域为基因组学与计算系统生物学。近几年主持国家自然科学基金两项、江苏省自然科学基金一项，教育部博士点基金一项，江苏省“六大人才高峰”项目一项，主持校级教改项目三项，以第一作者或通讯作者在国际著名SCI检索学术期刊Nucleic Acids Research, Journal of Theoretical Biology, Journal of Medical Virology, BMC Genomics等发表论文28篇，EI、ISTP收录论文30多篇，获发明专利授权2项，软件著作权一项。多次参与组织和参加国内国际学术会议。目前担任：中国人工智能学会生物信息学与人工生命专业委员会委员；中国计算机学会生物信息学专委会委员；江苏省生物医学工程学会理事；江苏省生物医学工程学会生物信息学专业委员会副主任委员。
学术成果
以第一作者或通讯作者在国际著名SCI检索学术期刊Nucleic Acids Research, Journal of Theoretical Biology, Journal of Medical Virology, BioSystems等发表论文28篇，EI、ISTP收录论文30多篇。1.Xiaofeng Song, Naibo Zhang, Ping Han, Rose K. Lai, Kai Wang, Wange Lu. Circular RNA Profile in Gliomas Revealed by Identification Tool UROBORUS. Nucleic Acids Research.2016,44(9):e87. (SCI IF#10.162).2.Xiaobai Zhang, Juan Cui, Daniel Nilsson; Kapila Gunasekera; Isabel Roditi; Astrid Chanfon; Xiaofeng Song, Huinan Wang, Ying Xu and Torsten Ochsenreiter. The Trypanosoma brucei Mitocarta and its Regulation and Splicing Pattern during Development. Nucleic Acids Research.2010,38(21):7378-7387. (SCI#689TK, IF#10.162) 3.Minghao Wang, Xiaofeng Song，Ping Han, Wei Li, Bin Jiang. New syntax to describe local continuous structure-sequence information for recognizing new pre-miRNAs. Journal of Theoretical Biology. 2010,264(2):578-584.（SCI# 588GG, IF#2.738）（corresponding author）4.Kun Sun, Xiaona Chen, Peiyong Jiang, Xiaofeng Song, Huating Wang, and Hao Sun. iSeeRNA: identification of long intergenic non-coding RNA transcripts from transcriptome sequencing data. BMC Genomics. 2013,14(Suppl 2):S7.(corresponding author)(SCI IF# 4.3)5.Xiao-feng Song，Ping Han，Yi-Ping Phoebe Chen. Genetic variation of the hemagglutinin of avian influenza virus H9N2. Journal of Medical Virology. 2011,83(5):838-846.（SCI#736BL, IF# 2.572）6.Xiaofeng Song; Minghao Wang; Yi-Ping Phoebe Chen; Ping Han; Hao Sun. Prediction of pre-miRNA with multiple stem-loops using pruning algorithm. Computers in Biology and Medicine. 2013 Jun 1;43(5):409-416.(corresponding author)（SCI, IF#1.485）7.Xiaofeng Song,Lei Cheng, Tao Zhou, Xuejiang Guo, Xiaobai Zhang, Ping Han, Yi-ping Phoebe Chen, Jiahao Sha. Predicting miRNA-Mediated Gene Silencing mode based on miRNA-target Duplex Features. Computers in Biology and Medicine. 2012, 42(1):1-6. （SCI, IF#1.485）8.Xiaobai Zhang. Xiaofeng Song, Huinan Wang。Characteristic comparison between two types of miRNA precursors in metazoan species。BioSystems,2010,100(2):144-149. (SCI# 599MX, IF#1.653）（corresponding author）9.Xiaofeng Song, Hao Jia,Tao Zhou, Xuejiang Guo, Ping Han, Xiaobai Zhang and Jiahao Sha. SProtP: a web server to recognize those short-lived proteins based on sequence-derived features in human cells. PLoS ONE.2011, 6(11): e27836. （SCI, IF#4.78）10.Xiaofeng Song, Wei-min Chen, Yi-Ping Phoebe Chen, Bin Jiang. Candidate Working Set Strategy based SMO Algorithm in Support Vector Machine. Information Processing & Management. 2009,45(5): 584-592. （corresponding author）（SCI# 481FP, IF# 2.106）
承担项目
1.主持国家自然科学基金（No.**）；2.主持国家自然科学基金（No.**）；3.主持教育部博士点基金（博导类，No.20**6）；4.主持2013年江苏省“六大人才高峰”项目（No.SWYY-021）5.主持江苏省自然科学基金（BK**）；6.主持校级教改项目三项；
