光谱显微图像分析(Spectroscopic Image Analysis)
计量学建模及计算(Chemometrics Modeling and Assessment)
生医光子学技术开发及应用 (D&A of Biomed Photonics Tech.)
光谱生物分析化学(Spectroscopic Bioanalytical Chemistry)
药物及肿瘤的光谱学检测 （Spectroscopic detection of Drug and Tumor）
个人简介
南京航空航天大学生物医学工程系教授，中国光学学会生物医学光子学专业委员会委员，中国生物医学工程学会纳米医学分会、中国电子学会生命电子学分会、日本分析化学学会等学会高级会员。发表文章七十余篇，一作及通讯作者SCI论文三十多篇。申请发明专利3项，已授权1项。主持NSFC面上项目、教育部博士学科点基金、江苏省自然科学基金和江苏省“六大人才高峰”高层次人才计划等项目。作为项目主要完成人参与完成2项美国NIH R01项目，2项日本文部省重大项目，3项国家自然科学基金面上项目。
指导江苏省优秀学术硕士学位论文1项（2017），研究生创新基金项目、校优秀硕士学位论文、校优秀本科毕业设计各2项。指导研究生获得研究生国家奖学金（2015、2016年度3人各20K）、中航工业奖学金（2017年度1人6K）、南京市第十二届自然科学优秀学术论文三等奖。
学术成果
部分代表性成果：[to update soon or to visit http://bmsi.nuaa.edu.cn/]
-------------------------------
【红外光谱成像/分析&化学计量学&荧光成像光谱&光子技术@生物医学&生物医学光子学】
[1] Zhi-Hua Mao, Jian-Hua Yin*, Xue-Xi Zhang, Xiao Wang, Yang Xia, Discrimination of healthy and osteoarthritic articular cartilage by Fourier transform infrared imaging and Fisher’s discriminant analysis, Biomed. Opt. Express, 7(2) 448-453, 2016（SCI IF3.648）
[2] Zhi-Hua Mao ?, Yue-Chao Wu ?, Xue-Xi Zhang, Hao Gao and Jian-Hua Yin*, Comparative study on identication of healthy and osteoarthritic articular cartilages by fourier transform infrared imaging and chemometrics methods, J Innov Opt Health Sci, 10, **, 2017 (SCI)
[3] Xue-Xi Zhang, Jian-Hua Yin*, Zhi-Hua Mao, Yang Xia, Discrimination of healthy and osteoarthritic articular cartilages by Fourier transform infrared imaging and partial least squares-discriminant analysis, J Biomed Opt, 20(6), 060501, 2015（SCI IF2.85）
[4] Xue-Xi Zhang, Zhi-Hua Mao, Jian-Hua Yin*, Yang Xia, Determination of collagen and proteoglycan concentration in osteoarthritic and healthy articular cartilage by Fourier transform infrared imaging and partial least square, Vib Spectrosc., 78, 49-53, 2015（SCI IF2.1）
[5] Zhi-Hua MAO, Xue-Xi ZHANG, Yue-Chao WU, Jian-Hua YIN*, XIA Yang, Fourier Transform Infrared Microscopic Imaging and Fisher Discriminant Analysis for Identification of Healthy and Degenerated Articular Cartilage, Chin J Anal Chem, 43, 518-522, 2015（SCI）(EN)
毛之华, 张学喜, 吴曰超，尹建华*，Xia Yang, 健康和病变关节软骨的傅里叶变换红外光谱显微成像及Fisher判别. 分析化学, 43: 518-522, 2015 (SCI) (CN)
[6] Jian-Hua Yin, Yang Xia*, "Proteoglycan Concentrations in Healthy and Diseased Articular Cartilage by Fourier Transform Infrared Imaging and Principal Component Regression", Spectrochim Acta A: Molecular and Biomolecular Spectroscopy, 133, 825-830, 2014 (SCI, IF=2.653)
[7] Xue-Xi Zhang, Zhi-Yan Xiao, Jian-Hua Yin*, et al. Concentration Determination of Collagen and Proteoglycan in Bovine Nasal Cartilage by Fourier Transform Infrared Imaging and PLS, Proc. of SPIE, 9230: 923015-1~7, 2014 (EI)
[8] 吴曰超, 张学喜, 毛之华, 尹建华*. 关节软骨内胶原纤维各向异性的红外光谱学显微成像研究, 光谱学与光谱分析, 36(7): 2071-2075, 2016 (SCI)
[9] 尹建华*，黄凤玲，钱志余，谢捷如，傅里叶变换红外光谱学显微成像技术在骨病研究中的应用和进展，光谱学与光谱分析, 34, 340-343, 2014 (SCI)
[10] 王潇，吴曰超，何俊豪，毛之华，张学喜，蔡金洋，王强，尹建华*, 关节软骨的荧光显微检测方法研究, 光散射学报, 28(2), 185-189, 2016
[11] 毛之华，尹建华*, 基于主成分分析的不同预处理方法对关节软骨分类的影响, 光散射学报, 28(3), 264-269, 2016
[12] 吴曰超, 尹建华*, 刘玉, 毛之华, 关节软骨红外光谱成像及分析方法研究，南京航空航天大学学报, 47, 421-427, 2015 (EI)
[13] 尹建华，关节软骨和骨关节炎的傅里叶变换红外光谱学显微成像研究进展，科学通报, 59 (27) ,2645 – 2651, 2014 (重核)
[14] 尹建华，关节软骨主成分的红外光谱学分析及表征，光散射学报，26(2)，213-218, 2014
[15] 尚林伟，尹建华*，软骨退变的显微荧光光谱研究?，中国科技论文，11(24)，2811-2815，2016
[16] Z. Xiao, J.H. Yin*, “Spectroscopic studies on bilirubin aggregate at liquid/liquid interface”, Anal. Bioanal. Chem., 405, 2723-2728, 2013 (SCI, IF=3.778)
[17] J.H. Yin*, Y. Xia, “Comparison of macromolecular component distributions in osteoarthritic and healthy cartilages by Fourier transform infrared imaging”, J Innov. Opt. Health Sci., 6, **, 2013 (SCI)
[18] J.H. YIN, Y. Xia*, “Concentration Profiles of Collagen and Proteoglycan in Articular Cartilage by Fourier Transform Infrared Imaging and Principal Component Regression”, Spectrochim. Acta A, 88, 90-96, 2012 (SCI, IF=2.663)
[19] J.H. YIN, Y. Xia*, “Chemical Visualization of Individual Chondrocytes in Articular Cartilage by Attenuated-Total-Reflection Fourier Transform Infrared Microimaging”, Biomed. Opt. Express, 2, 937-945, 2011 (SCI, IF=3.648)
[20] J.H. YIN, Y. Xia*, “Depth-dependent Anisotropy of Proteoglycan in Articular Cartilage by Fourier Transform Infrared Imaging”, Vib. Spectrosc., 57, 338-341, 2011 (SCI, IF=2.083)
[21] J.H. YIN, Y. Xia*, “Macromolecular Concentrations in Bovine Nasal Cartilage by Fourier Transform Infrared Imaging and Principal Component Regression”, Appl. Spectrosc., 64, 1199-1208, 2010 (SCI, IF=1.663)
-------------------------------
【共焦显微拉曼&圆二色谱&荧光光谱&界面分子聚集@生物分析化学】
[22] J.H. Yin, H. Watarai*, “Effect of Chloroform on Complexation and Chiral Aggregation of Bilirubin–Bovine Serum Albumin at Heptane/Water Interface”, J. Colloid Interface Sci., 329, 325-330, 2009 (SCI, IF=3.263)
[23] D. Tokunaga, H. Takechi, J.H. Yin, H. Watarai*, T. Ohde, “Microscopic Observation of Second Harmonic Generation from Chiral Surfaces”, Anal. Sci., 25, 311-314, 2009 (SCI, IF=1.255)
[24] J.H. Yin, H. Watarai*, “Chiral Complexation and Aggregation of Bilirubin with Serum Albumin at Liquid/Liquid Interface”, Anal. Bioanal. Chem., 389, 895-902, 2007 (SCI, IF=3.778)
[25] J.H. Yin, H. Watarai*, “Resonance Raman Spectroscopic Study on Chiral Aggregation of Bilirubin-Bovine Serum Albumin Complex Formed at Liquid/Liquid Interface”, Anal. Sci., 23 841-846, 2007 (SCI, IF=1.255)
-------------------------------
【光纤Raman光谱@分子光谱学&光学光子学】
[26] J.H. Yin*, Z.Y. Xiao, Z.W. Li, “Ultralow concentration beta-carotene molecule detection by liquid-core optical fiber resonance Raman spectroscopy”, Vib. Spectrosc., 62, 7-9, 2012 (SCI, IF=2.083)
[27] J.H. Yin, Z.W. Li*, “Resonance Raman Spectra of n-pi* Singlet–triplet Transition of p- benzoquinone at Low Concentrations”, Spectrochim. Acta Part A, 61, 495–498, 2005 (SCI, IF=2.098)
[28] J.H. Yin, Z.W. Li*, Y.J. Tian, Z.W. Sun, X.L. Song, “A Study on Raman Scattering Cross Section of Carbon Tetrachloride at low Concentrations”, Appl. Phys. B: Lasers and Optics, 80, 573-576, 2005 (SCI, IF=2.189)
[29] J.H. Yin, Z.W. Li*, C.N. Ren, L.Y. Zhang, “Visible Absorption Spectra of n-pi* Singlet-Triplet Transition of p-benzoquinone in CS2 and its Resonance Raman Spectra”, Spectrosc. Spect. Anal., 25, 1821-1823, 2005 (SCI)
[30] J.H. Yin, S.Q. Gao, Z.W. Li*, Y.N. Yu, G.H. Lu, Y.J. Tian, “Effect of Solution Concentration on Raman Scattering Cross Section of Carbon Tetrachloride”, J. Raman Spectrosc., 35, 1042-1046, 2004 (SCI, IF=3.087)
[31] J.H. Yin, S.Q. Gao, X.F. Xu, Z.W. Li*, “Experimental Studies on Effect of Concentration of CS2 on Linewidth and Frequency Shift of Raman Spectrum”, Chem. J. Chin. Univ., 23, 2300- 2302, 2002 (SCI)
承担项目
主持项目：
1. 2016 江苏省第十三批“六大人才高峰”高层次人才计划项目
2. 国家自然科学基金面上项目 ( **)
3. 高等学校博士学科点专项科研基金 (20**7)
4. 江苏省自然基金 (BK**)
5. 南京航空航天大学引进人才启动基金 (1003-56YAH13005)
参研项目：
2 项美国NIH R01项目 2008-2012
2 项日本文部省重大项目 2005-2008
3 项国家自然科学基金 2000-2005
http://bmsi.nuaa.edu.cn/
https://terminator314.github.io/home.html
http://gsmis.nuaa.edu.cn:81/gmis/xkjsb/yjsdsfc.aspx?id=03163
Thanks for your visiting and welcome to access to our group.
