职务： 博士生导师
联系电话： **
办公地址： 南京大学仙林校区化学楼E301
电子邮箱： yingliu@nju.edu.cn

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个人简介


刘颖，女，教授，博士生导师，国家级青年人才计划入选者。国家“优秀青年”基金、江苏省“****”基金、****、“双创人才”入选者”。2004年从南京大学化学化工学院获得学士学位，2007年从南京大学化学化工学院获得分析化学硕士学位，2012年从美国加州大学河滨分校（University of California Riverside）获得分析化学博士学位。2012-2013年在德国博世集团北美研发中心（Robert Bosch llc Research and Technology Center）任研究员。2013-2015年在加州大学戴维斯分校（University of California Davis）生物医学工程系从事博士后研究工作，并兼任Sersense Inc.生物科技公司项目负责人。2015年7月起任南京大学化学化工学院化学系生命分析化学国家重点实验室教授。

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工作经历


2012-2013年在德国博世集团北美研发中心（Robert Bosch llc Research and Technology Center）任研究员。2013-2015年在加州大学戴维斯分校（University of California Davis）生物医学工程系从事博士后研究工作，并兼任Sersense Inc.生物科技公司项目负责人。2015年7月起任南京大学化学化工学院化学系生命分析化学国家重点实验室教授。

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研究方向


1）基于智能响应材料的体内成像与精准治疗。2）生物功能化表界面与即时现场分子诊断器件。3）蛋白质超高灵敏分析测定新方法。


学术成果


1.体内成像：
(1)Kewei Ren, Yifan Xu, Ying Liu*, Min Yang, Huangxian Ju* A Responsive Nano String Light for Highly Efficient mRNA Imaging in Living Cells via Accelerated DNA Cascade Reaction ACS Nano 2018,12,263.??
2.精准治疗：
(1)Xiaobo Zhang, Weiwei Chen, Xiaoyu Xie, Yuyi Li, Desheng Chen, Zhicong Chao, Chenghui Liu, Haibo Ma, Ying Liu*, Huangxian Ju* Boosting luminance energy transfer efficiency in upconversion nanoparticles with an energy-concentrating zoneAngew. Chem. Int. Ed. 2019, 58, 12117.
(2)Yue Zhang, Yue Zhang, Guobin Song, Yuling He, Xiaobo Zhang, Ying Liu*, Huangxian Ju* A DNA-Azobenzene nanopump fueled by upconversion luminance for controllable intracellular drug release Angew. Chem. Int. Ed. 2019, DOI: 10.1002/anie..
(3)Yuling He, Shuwen Guo, Lina Wu, Pengwen Chen, Leyong Wang, Ying Liu*, Huangxian Ju* Near-infrared boosted ROS responsive siRNA delivery and cancer therapy with sequentially peeled upconversion nano-onions Biomaterials2019, 225, 119501.
(4)Yue Zhang, Kewei Ren, Xiaobo Zhang, Zhicong Chao, Yuqin Yang, Deju Ye, Zhihui Dai, Ying Liu*, Huangxian Ju* Photo-tearable Tape Close-wrapped Upconversion Nanocapsules for Near-infrared Modulated Efficient siRNA Delivery and Therapy Biomaterials 2018,163,55.
(5)Kewei Ren, Yue Zhang, Xiaobo Zhang, Ying Liu*, Min Yang, Huangxian Ju*In situ siRNA assembly in living cells for gene therapy with microRNA triggered cascade reactions templated by nucleic acids ACS Nano 2018, 12, 10797.
(6)Kewei Ren#,Ying Liu#, Jie Wu, Yue Zhang, Jing Zhu, Min Yang, Huangxian Ju* A DNA Dual Lock-and-key Strategy for Cell-subtype-specific siRNA Delivery Nat. Commun. 2016,7,13580.(共同一作);
3.生物功能化表界面:
(1)Jingxing Guo, Zhihao Zhong, Yumei Li, Ying Liu*, Ruiyong Wang*, Huangxian Ju* “Three-in-One” SERS adhesive tape for rapid sampling, release, and detection of wound infectious pathogens ACS Appl. Mater. Interfaces2019, 11, 36399-36408.
(2) Jingxing Guo,# Ying Liu,# Yunlong Cheng, Jianqi Li, Huangxian Ju* A multifunctional SERS sticky note for real-time quorum sensing tracing and inactivation of bacterial biofilms Chem. Sci. 2018,9,5906.
(3)Xiao Meng, Junjie Hu, Zhicong Chao, Ying Liu*, Huangxian Ju, Quan Cheng* Thermoresponsive Arrays Patterned via Photoclick Chemistry: Smart MALDI Plate for Protein Digest Enrichment, Desalting, and Direct MS Analysis ACS Appl.Mater.Interfaces 2018,10,1324.
(4)Ying Liu, Michael C. Young, Orly Moshe, Quan Cheng*, Richard J. Hooley* A Membrane-bound Synthetic Receptor that Promotes Growth of a Polymeric Coating at the Bilayer-Water Interface Angew. Chem. Int. Ed. 2012, 51, 7748.
(5)Ying Liu, Puhong Liao, Quan Cheng*, Richard J. Hooley* Protein and Small Molecule Recognition Properties of Deep Cavitands in a Supported Lipid Membrane Determined by Calcination-Enhanced SPR Spectroscopy J.Am. Chem. Soc. 2010,1342,10383.

4.?高灵敏生物分析与即时检测器件：
(1) Lina Wu, Yingfei Wang, Rong He, Yue Zhang, Yuling He, Chao Wang, Zhenda Lu, Ying Liu*, Huangxian Ju Fluorescence hydrogel array based on interfacial cation exchange amplification for highly sensitive microRNA detection Anal. Chim. Acta2019,1080,206.
(2)Ying Liu, Zimple Matharu, Ali Rahimian, Alexander Revzin* Detecting multiple cell-secreted cytolines from the same aptamer-functionalized electrode Biosens. Bioelectron.2015,64,43.
(3)Chuanbo Gao#,Zhenda Lu#,Ying Liu#,Qiao Zhang, Miaofang Chi, Quan Cheng, Yadong Yin* Highly Stable Silver Nanoplates for Surface Plasmon Resonance Biosensing Angew.Chem.Int.Ed.2012,51,5629. (共同一作).
(4)Ying Liu, Quan Cheng* Detection of Membrane-Binding Proteins by Surface Plasmon Resonance with an All-Aqueous Amplification SchemeAnal.Chem.2012,84,3179.



课程名称、上课时间地点


表面材料分析，研究生专业必修课

教学大纲、考试要求




教学资源（上课讲义、参考资料等）





课题组风采