学术学位博导
--> 职称:教授
单位:生物化学与分子生物学系
cxsun@njmu.edu.cn
专业:生物化学与分子生物学
个人简介
发表论文:
Triglyceride-rich lipoprotein modulates inflammatory VCAM-1 expression via differential regulation of endoplasmic reticulum stress and IRF-1 expression.
ADAM15 deficiency attenuates pulmonary hyperpermeability and acute lung injury in lipopolysaccharide-treated mice.
Interleukin 18 function in atherosclerosis is mediated by the interleukin 18 receptor and the Na-Cl co-transporter.
ADAM15 contributes to atherosclerosis by mediating endothelial barrier dysfunction via Src family kinase activity.
IRF-1 and miRNA126 Modulate VCAM-1 Expression in Response to a High Fat Meal.
nmMLCK deficiency ameliorates atherosclerosis in ApoE-deficient mice via reduced endothelial barrier dysfunction and monocyte migration.
Cystatin C Deficiency Promotes Inflammation in Angiotensin II-Induced Abdominal Aortic Aneurisms in Atherosclerotic Mice.
ADAM15 regulates endothelial permeability and neutrophil migration via Src/ERK1/2.
11,12-Epoxyecosatrienoic acids mitigate endothelial dysfunction associated with estrogen loss and aging: Role of membrane depolarization.
Shear stress modulates VCAM-1 expression in response to TNFα and dietary lipids via interferon regulatory factor-1 in cultured endothelium.
教材专著:
科研成果:
一种可预测人冠状动脉粥样硬化性心脏病严重缺血风险的mRNA及其应用
目前承担的科研项目:
心血管疾病的转化医学研究双创团队
IRF-1介导的内皮细胞功能失调在动脉粥样硬化中的作用(81670410)
mTOR信号在动脉内皮细胞炎性激活中的作用及机制(18KJA310001)
mTOR信号对内皮细胞骨架及屏障功能的调控(81870355)
已经完成的科研项目: