研究员，博士生导师
教育经历：
1998.10-2003.03，岩手大学（日本），农学博士，应用昆虫学
1995.09-1998.08，安徽农业大学，农学硕士，蚕学
1991.09-1995.07，安徽农业大学，农学学士，蚕学
工作经历：
2021.01至今，江苏科技大学生物技术学院/中国农科院蚕业研究所，研究员
2014.11-2020.12，中国科学院分子植物科学卓越创新中心，研究员
2010.02-2014.11，中国科学院上海植物生理生态研究所，副研究员
2008.06-2010.01，美国圣母大学生物科学系，博士后
2006.01-2008.05，美国肯塔基大学昆虫学系，博士后
2003.06-2005.12，日本农业生物资源研究所，博士后
研究领域：
昆虫独特的生命特征，包括变态发育、性别决定与分化、取食特性等是其具有广泛生物与环境适应性的重要原因。阐明这些生命特征的分子机制、揭示相关重要基因的功能是现代昆虫科学的核心课题。家蚕不仅是一种重要的经济昆虫，也是鳞翅目代表性模式昆虫，以家蚕为对象开展的功能基因研究不仅有助于深入阐明昆虫特有生命特征的分子机制，还对鳞翅目害虫的遗传防治有重要的借鉴意义。本课题组（昆虫功能遗传学研究组）长期致力于创建和优化以家蚕为代表的昆虫遗传操作和基因编辑体系，并以此为重要手段开展发育和性别的遗传调控、昆虫食性调控的分子机制、创建生物新素材等多项研究。
主持科研项目：
1.国家****科学基金（**），昆虫生理生化，2020.01-2024.12，400万。
2.江苏****特别资助，2021-2023，400万。
3.国家自然科学基金联合基金项目（U**），空间环境对家蚕胚胎发育的影响及变异机理的研究，2018.01-2020.12，160万。
4.国家自然科学基金面上项目（**），Doublesex基因在家蚕性别调控通路中的作用机制研究，2016.01-2019.12，66万。
5.中国科学院重点部署项目（KJZD-EW-L12），剪接体复合物的高效表达系统与作用机制研究子课题：家蚕高效表达系统的建立，2015.05-2017.12，190万。
6.国家自然科学基金面上项目（**），胚胎期致死基因pdp-1在亚洲玉米螟遗传控制中的应用研究，2013.01-2016.12，80万。
7.国家重点基础研究发展计划（973计划，2012CB114101），害虫暴发成灾的遗传与行为机理子课题：害虫发育与变态的遗传机制，2012.01-2016.08，100万。
发表论文（通讯或第一作者论文）：
Sun Lili, Zhang Zhongjie, Zhang Ru, Yu Ye, Yang Fangying, Tan Anjiang*. Molecular disruption of ion transport peptide receptor results in impaired water homeostasis and developmental defects inBombyx mori. Frontiers in Physiology.doi.org/10.3389/fphys.2020.00424. 2020
Zhang Ru, Zhang Zhongjie, Huang Yongping, Qian Airong,Tan Anjiang*. A single ortholog of teashirt and tiptop regulates larval pigmentation and adult appendage patterning inBombyxmori. Insect Biochemistry and Molecular Biology. doi: 10.1016/j.ibmb.2020.103369.2020
Zhang Zhongjie^#, Zhang Shuaishuai^#, Niu Baolong^#, Ji Dongfeng, Liu Xiaojing, Li Muwang, Bai Hua, Palli Subba, Wang Chengzhu, Tan Anjiang*. A determining factor for insect feeding preference in the silkworm, Bombyx mori, PLoS Biology,17(2):e**. 2019
Xu Jun^#, Dong Qinglin^#, Yu Ye, Niu Baolong, Ji Dongfeng, Li Muwang, Huang Yongping, Chen Xin, Tan Anjiang*. Mass spider silk production through targeted gene replacement inBombyxmori. PNAS. 115(35): 8757-8762. 2018
Zhang Zhongjie^#, Niu Baolong^#, Ji Dongfeng, Li Muwang, Li Kai, James Anthony A*, Tan Anjiang*, Huang Yongping*. Silkworm genetic sexing through W chromosome-linked, targeted gene integration. PNAS. 115(35): 8752-8756. 2018
Li Zhiqian, You Lang, Yan Dong, James Anthony A, Huang Yongping, Tan Anjiang*. Bombyxmorihistone methyltransferase BmAsh2 is essential for silkworm piRNA-mediated sex determination. PLoS Genetics. 14(2):e**. 2018
Liu Zulian, Ling Lin, Xu Jun, Zeng Baosheng, Huang Yongping, Shang Peng, Tan Anjiang*. MicroRNA-14 regulates larval development time inBombyxmori. Insect Biochemistry and Molecular Biology.93: 57-65. 2018
Xu Jun, Chen Shuqing, Zeng Baosheng, James Anthony A, Tan Anjiang*, Huang Yongping*. Bombyx moriP-element somatic inhibitor (BmPSI) is a key auxiliary factor for silkworm male sex determination. PLoS Genetics13(1): e**.2017
Chen Shuqing^#, Hou Chengxiang^#, Bi Honglun, Wang Yueqiang, Xu Jun, Li Muwang, James Anthony A, Huang Yongping*, Tan Anjiang*. Transgenic clustered regularly interspaced short palindromic repeat/Cas9-mediated viral gene targeting for antiviral therapy of Bombyx moriNucleopolyhedrovirus. Journal of Virology91(8): e02465-16. 2017
Zeng Baosheng, Huang Yuping, Xu Jun, Shiotsuki Takahiro, Bai Hua, Palli Subba Reddy, Huang Yongping,Tan Anjiang*. FOXO transcription factor controls insect growth and development by regulating juvenile hormone degradation in the silkworm, Bombyxmori. Journal of Biological Chemistry.292(28):11659-11669. 2017
Zhang Zhongjie, Liu Xiaojing, Shiotsuki Takahiro, Wang Zhisheng, Xu Xia, Huang Yongping, Li Muwang, Li Kai*, Tan Anjiang*. Depletion of juvenile hormone esterase extends larval growth in Bombyx mori. Insect Biochemistry and Molecular Biology81: 72-79. 2017
Zeng Baosheng, Zhan Shuai, Wang Yueqiang, Huang Yuping, Xu Jun, Liu Qun, Li Zhiqian, Huang Yongping*, Tan Anjiang*. Expansion of CRISPR targeting sites in Bombyx mori. Insect Biochemistry and Molecular Biology.72: 31-40. 2016
Li Zhiqian, You Lang, Zeng Baosheng, Ling Lin, Xu Jun, Chen Xu, Zhang Zhongjie, Subba Reddy Palli, Huang Yongping*, Tan Anjiang*. Ectopic expression of the ecdysone oxidase impairs tissue degeneration inBombyx mori.Proceedings of the Royal Society of Lodon B: Biological Sciences282(1809): **.2015
Ling Lin, GeXie, Li Zhiqian, Zeng Baosheng, Xu Jun, Shang Peng, Anthony A. James, Huang Yongping*, Tan Anjiang*.MiR-2 family targets awd and fng to regulate wing morphogenesis inBombyx mori.RNA Biology12: 742-748. 2015
ZhangZhongjie, Abu F.MAslam, Liu Xiaojing, Li Muwang, Huang Yongping, Tan Anjiang*.Functional analysisofBombyxWnt1 during embryogenesis using the CRISPR/Cas9 system.Journal of Insect Physiology. 79:73-9. 2015
Xu Jun, Bi Honglun, Chen Rongmei, AF Aslam, Li Zhiqian, Ling Lin, Zeng Baosheng, Huang Yongping, and Tan Anjiang*. Transgenic characterization of two testis-specific promoters in the silkworm, Bombyx mori.Insect Molecular Biology. 24(2):183-90. 2015
Li Zhiqian, Zeng Baosheng, Ling Lin, Xu Jun, You Lang, Abu F. M. Aslam, Tan Anjiang*, Huang Yongping*. Enhancement of larval RNAi efficiency by over-expressing the Argonaute 2 inBombyx mori.International Journal of Biological Sciences.11(2): 176-185. 2015
Xu Jun, Wang Yueqiang, Li Zhiqian, Ling Lin, Zeng Baosheng, Anthony A James,Tan Anjiang*, Huang Yongping*. Transcription activator-like effector nuclease (TALEN)-mediated female-specific sterility in the silkworm, Bombyx mori. Insect Molecular Biology.23(6): 800-7.2014
Xu Jun, Wang Yueqiang, Li Zhiqian, Ling Lin, Zeng Baosheng, You Lang, Chen Yazhou, AF Aslam, Huang Yongping, Tan Anjiang*. Functional characterization of the vitellogenin promoter in the silkworm, Bombyx mori. Insect Molecular Biology. 23(5):550-7. 2014
Chen Yazhou, Li Muwang, Iftakher Islam, You Lang, Wang Yueqiang, Li Zhiqian, Ling Lin, Zeng Baosheng, Xu Jun, Huang Yongping, Tan Anjiang*. Allelic-specific expression in relation to Bombyx moriresistance to Bt toxin.Insect Biochemistry and Molecular Biology.54: 53-60.2014
Ling Lin, Ge Xie, Li Zhiqian, Zeng Baosheng, Xu Jun, AF Aslam, Song Qisheng, Shang Peng, Huang Yongping*, Tan Anjiang*. MicroRNA Let-7 regulates molting and metamorphosis in the silkworm, Bombyx mori. Insect Biochemistry and Molecular Biology.53:13-21.2014
Li Zhiqian, Ge Xie, Ling Lin, Zeng Baosheng, Xu Jun, AF Aslam, You Lang, Subba Reddy Palli, Huang Yongping*, Tan Anjiang*. CYP18A1 regulates tissue-specific steroid hormone inactivation inBombyxmori. Insect Biochemistry and Molecular Biology.54: 33-41.2014
Li Zhiqian, Jiang Jianhao, Chen Yazhou, You Lang, Niu Baolong, Meng Zhiqi, Huang Yongping, Tan Anjiang*. PDP1 regulates energy metabolism through the IIS-TOR pathway in the red flour beetle, Tribolium castaneum. Archive of Insect Biochemistry and Physiology85(3):127-36. 2014
Wang Yueqiang, Li Zhiqian, Xu Jun,Zeng Baosheng, Ling Lin, You Lang, Chen Yazhou, Huang Yongping*, Tan Anjiang*. The CRISPR/Cas System mediates efficient genome engineering in Bombyx mori. Cell Research23(12):1414-6. 2013
Tan Anjiang^#, Fu Guoliang^#, Jin Li, Guo Qiuhong, Li Zhiqian, Niu Baolong, Meng Zhiqi, Neil I. Morrison, Alphey Luke*, Huang Yongping*. Transgene-based, female-specific lethality system for genetic sexing of the silkworm, Bombyx mori. PNAS110(17): 6766-70. 2013
Ge Xie, Zhang Yong, Jiang Jianhao, Yang Xiaonan, Li Zhiqian, Huang Yongping, Tan Anjiang*. Identification of microRNAs in Helicoverpa armigeraand Spodoptera liturabased on deep sequencing and homology analysis. International Journal of Biological Sciences9(1): 1-15.2013
Liu Dan, Yan Shangchun*, Huang Yongping, Tan Anjiang*, David W. Stanley, Song Qisheng. Genetic transformation mediated by piggyBac in the Asian corn borer, Ostrinia furnacalis(Lepidoptera: Crambidae). Archive of Insect Biochemistry and Physiology80(3): 140-50.2012
Tan Anjiang, Subba Reddy Palli. Identification and characterization of nuclear receptors from the red flour beetle, Tribolium castaneum. Insect Biochemistry and Molecular Biology38(4): 430-9. 2008
Tan Anjiang, Subba Reddy Palli. Ecdysone receptor isoforms play distinct roles in controlling molting and metamorphosis in the red flour beetle, Tribolium castaneum. Molecular and cellular Endocrinology 291(1-2): 42-9. 2008
Tan Anjiang,Hiromasa Tanaka, Toshiki Tamura, Takahiro Shiotsuki. Precocious metamorphosis in transgenic silkworms overexpressing juvenile hormone esterase. PNAS 102(33): 11751-6. 2005

联系方式：
江苏科技大学生物技术学院/中国农业科学院蚕业研究所
江苏省镇江市丹徒区长晖路666号
邮编：212100
E-mail:bombyx@126.com