叶俊梅，女，博士，生命科学与技术学院副教授，硕士生导师。
受教育经历：
1999/9-2004/6，武汉大学临床医学，学士；2004/9-2006/6，武汉大学内科学，硕士；2008/9-2011/6，武汉大学内科学，博士；2009/5-2013/2，西班牙莱里达大学生物化学，博士。
工作经历：
2006/7-2008/8，广东省梅州市嘉应医学院，助教；2013/2-2014/8，南京大学基础医学院，助理研究员；2014/10至今，中国药科大学生命科学与技术学院，生物化学教研室任职。
研究方向：
1. 心肌肥厚及心力衰竭的分子机制及药物治疗。
2. 糖尿病引起心肌功能及代谢紊乱的分子机制及药物治疗。
主持课题：
1. 国家自然科学青年基金，（编号：）：心脏Endo G缺失导致心肌肥大的机制研究。
2. 江苏省青年基金，（编号：BK）：心肌细胞Endo G缺失导致心肌肥大的分子机制研究。
3. 江苏省留学回国人员资助项目：AKT2在心脏发育过程中的机制研究。
发表文章：
1). IL-6: A Potential Role in Cardiac Metabolic Homeostasis.Xu Y, Zhang Y*,Ye J*.Int J Mol Sci.2018 Aug 21;19(9). pii: E2474. doi: 10.3390/ijms**. Review.
2)Shuai Yang^#, Dandan Chen^#, Fan Chen, Xinmei Zhao, Yubin Zhang, Zhe Li, Liang Jin, Yitao Xu, Daniel Sanchis, Junmei Ye.Deletion of AKT2 preserves cardiac function by blocking IL-6-mediated injury and restores blood pressure during angiotensin II/high salt diet-induced hypertension. J Hypertension.2018 Apr;36(4):834-846.
3). Chen F^#, Chen D^#, Zhao X, Yang S, Li Z, Sanchis D, Jin L, Qiang X, Wang K, Xu Y, Zhang Y, Ye J*. Interleukin-6 deficiency facilitates myocardial dysfunction during high fat diet-induced obesity by promoting lipotoxicity and inflammation.Biochim Biophys Acta-Mol Base Dis.2017 Dec;1863(12):3128-3141.
4). Chen F^#, Chen D^#, Zhang Y, Jin L, Zhang H, Pan T, Su Y, Wan M, Wang X, Xu Y,Ye J. Interleukin-6 deficiency attenuates angiotensin II-Induced cardiac pathogenesis with increased myocyte hypertrophy, Biochem Biophys Res Commun.2017 Dec 16;494(3-4):534-541.
5). Chen D, Chen F, Xu Y, Zhang Y, Li Z, Zhang H, Pan T, Su Y, Wan M, Wang X,Ye J. AKT2 deficiency induces retardation of myocyte development through EndoG-MEF2A signaling in mouse heart.Biochem Biophys Res Commun.2017 Dec 2;493(4):1410-1417.
6). Shuai Yang, Xinmei Zhao, Hui Xu, Fan Chen, Yitao Xu, Zhe Li , Daniel Sanchis, Liang Jin, Yubin Zhang*, Junmei Ye*. AKT2 Blocks Nucleus Translocation of Apoptosis-Inducing Factor (AIF) and Endonuclease G (EndoG) While Promoting Caspase Activation during Cardiac Ischemia. Int J Mol Sci.2017 Mar 6;18(3). pii: E565.
7). Ye J^#,Llorian M^#,Cardona M,Rongvaux A,Moubarak RS,Comella JX,Bassel-Duby R,Flavell RA,Olson EN,Smith CW,Sanchis D*, A pathway involving HDAC5, cFLIP and caspases regulates expression of the splicing regulator Polypyrimidine Tract Binding Protein in the heart. J Cell Sci. 2013 Apr 1;126(Pt 7):1682-91.
8). Ye J, Cardona M, Llovera M, Comella JX, Sanchis D*. Translation of Myocyte Enhancer Factor-2 is induced by hypertrophic stimuli in cardiomyocytes through a Calcineurin-dependent pathway. J Mol Cell Cardiol.2012.53(4):578-87.
9). McDermott-Roe C,Ye J,Ahmed R,Sun XM,Serafín A,Ware J,Bottolo L,Muckett P,Ca?as X,Zhang J,Rowe GC,Buchan R,Lu H,Braithwaite A,Mancini M,Hauton D,Martí R,García-Arumí E,Hubner N,Jacob H,Serikawa T,Zidek V,Papousek F,Kolar F,Cardona M,Ruiz-Meana M,García-Dorado D,Comella JX,Felkin LE,Barton PJ,Arany Z,Pravenec M,Petretto E,Sanchis D*, Cook SA*, Endonuclease G is a novel determinant of cardiac hypertrophy and mitochondrial function. Nature. 5;478(7367):114-8. 2011.
联系方式：junmeiye@126.com