Prof. Matthew T.V. Chan
MB BS, FANZCA, FHKCA, FHKAM(Anaesthesiology)

Professor
Department of Anaesthesia and Intensive Care
The Chinese University of Hong Kong

Honorary Consultant
Prince of Wales Hospital
Shatin, NT Hong Kong SAR

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Publications:
For details about citations arising from my publications and links to online versions of some of the publications, refer to:
http://www.researcherid.com/rid/J-2884-2013(Researcher ID:J-2884-2013)


2020

Li Z, Huang C, Yang B, Hu W, Chan MT, Wu WKK. Emerging roles of long non-coding RNAs in osteonecrosis of the femoral head. Am J Transl Res. 2020 September 15;12(9):5984-91.


Liu YZ, Chu R, Lee A, Gomersall CD, Zhang L, Gin T, Chan MTV, Wu WKK, Ling L. A surveillance method to identify patients with sepsis from electronic health records in hong kong: A single centre retrospective study. BMC Infect Dis. 2020 September 07;20(1):652-x.


Short TG, Leslie K, Campbell D, Frampton C, Chan MTV, Myles PS, Balanced Anaesthesia Study Group. Deep anaesthesia - authors' reply. Lancet. 2020 September 05;396(10252):666-7.


Wang K, Liu X, Liu Q, Ho IH, Wei X, Yin T, Zhan Y, Zhang W, Zhang W, Chen B, Gu J, Tan Y, Zhang L, Chan MT, Wu WK, Du B, Xiao J. Hederagenin potentiated cisplatin- and paclitaxel-mediated cytotoxicity by impairing autophagy in lung cancer cells. Cell Death Dis. 2020 August 13;11(8):611-5.


Xia X, Wu WKK, Wong SH, Liu D, Kwong TNY, Nakatsu G, Yan PS, Chuang YM, Chan MW, Coker OO, Chen Z, Yeoh YK, Zhao L, Wang X, Cheng WY, Chan MTV, Chan PKS, Sung JJY, Wang MH, Yu J. Bacteria pathogens drive host colonic epithelial cell promoter hypermethylation of tumor suppressor genes in colorectal cancer. Microbiome. 2020 July 16;8(1):108-4.


Li Z, Li X, Shen J, Zhang L, Chan MTV, Wu WKK. Emerging roles of non-coding RNAs in scoliosis. Cell Prolif. 2020 February 01;53(2):e12736.


Turan A, Artis AS, Hanline C, Saha P, Maheshwari K, Kurz A, Devereaux PJ, Duceppe E, Patel A, Tiboni M, Ruetzler K, Pearse R, Chan MTV, Wu WKK, Srinathan S, Garg AX, Sapsford R, Sessler DI. Preoperative vitamin D Liu Y, Zhu Z, Ho IHT, Shi Y, Li J, Wang X, Chan MTV, Cheng CHK. Genetic deletion of miR-430 disrupts maternal-zygotic transition and embryonic body plan. Front Genet. 2020 August 04;11:853.


Sun J, Liang F, Wu Y, Zhao Y, Miao Z, Zhang L, Gelb AW, Chan MTV, Peng Y, Han R, CANVAS Pilot Trial Investigators. Choice of ANesthesia for EndoVAScular treatment of acute ischemic stroke (CANVAS): Results of the CANVAS pilot randomized controlled trial. J Neurosurg Anesthesiol. 2020 January 01;32(1):41-7.


Duceppe E, Patel A, Chan MTV, Berwanger O, Ackland G, Kavsak PA, Rodseth R, Biccard B, Chow CK, Borges FK, Guyatt G, Pearse R, Sessler DI, Heels-Ansdell D, Kurz A, Wang CY, Szczeklik W, Srinathan S, Garg AX, Pettit S, Sloan EN, Januzzi JL, McQueen M, Buse GL, Mills NL, Zhang L, Sapsford R, Pare G, Walsh M, Whitlock R, Lamy A, Hill S, Thabane L, Yusuf S, Devereaux PJ. Preoperative N-terminal pro-B-type natriuretic peptide and cardiovascular events after noncardiac surgery: A cohort study. Ann Intern Med. 2020 January 21;172(2):96-104.


Sessler DI, Conen D, Leslie K, Yusuf S, Popova E, Graham M, Kurz A, Villar JC, Mrkobrada M, Sigamani A, Biccard BM, Meyhoff CS, Parlow JL, Guyatt G, Xavier D, Chan MTV, Kumar PA, Forget P, Malaga G, Fleischmann E, Amir M, Torres D, Wang CY, Paniagua P, Berwanger O, Srinathan S, Landoni G, Manach YL, Whitlock R, Lamy A, Balasubramanian K, Gilron I, Turan A, Pettit S, Devereaux PJ, Perioperative Ischemic Evaluation-2 Trial (POISE-2) Investigators. One-year results of a factorial randomized trial of aspirin versus placebo and clonidine versus placebo in patients having noncardiac surgery. Anesthesiology. 2020 April 01;132(4):692-701.


Ho J, Chan H, Liang Y, Liu X, Zhang L, Li Q, Zhang Y, Zeng J, Ugwu FN, Ho IHT, Hu W, Yau JCW, Wong SH, Wong WT, Ling L, Cho CH, Gallo RL, Gin T, Tse G, Yu J, Chan MTV, Leung CCH, Wu WKK. Cathelicidin preserves intestinal barrier function in polymicrobial sepsis. Crit Care. 2020 February 10;24(1):47-5.


Li CK, Xu Z, Ho J, Lakhani I, Liu YZ, Bazoukis G, Liu T, Wong WT, Cheng SH, Chan MT, Zhang L, Gin T, Wong MC, Wong ICK, Wu WKK, Zhang Q, Tse G. Association of NPAC score with survival after acute myocardial infarction. Atherosclerosis. 2020 May 01;301:30-6.


Thomas S, Borges F, Bhandari M, De Beer J, Urrutia Cuchi G, Adili A, Winemaker M, Avram V, Chan MTV, Lamas C, Cruz P, Aguilera X, Garutti I, Alonso-Coello P, Villar JC, Jacka M, Wang CY, Berwanger O, Chow C, Srinathan S, Pettit S, Heels-Ansdell D, Rubery P, Devereaux PJ, VISION Investigators. Association between myocardial injury and cardiovascular outcomes of orthopaedic surgery: A vascular events in noncardiac surgery patients cohort evaluation (VISION) substudy. J Bone Joint Surg Am. 2020 May 20;102(10):880-8.


Chan MTV, Hedrick TL, Egan TD, Garcia PS, Koch S, Purdon PL, Ramsay MA, Miller TE, McEvoy MD, Gan TJ, Perioperative Quality Initiative (POQI) 6 Workgroup. American society for enhanced recovery and perioperative quality initiative joint consensus statement on the role of neuromonitoring in perioperative outcomes: Electroencephalography. Anesth Analg. 2020 May 01;130(5):1278-91.


Conen D, Alonso-Coello P, Douketis J, Chan MTV, Kurz A, Sigamani A, Parlow JL, Wang CY, Villar JC, Srinathan SK, Tiboni M, Malaga G, Guyatt G, Sivakumaran S, Rodriguez Funes MV, Cruz P, Yang H, Dresser GK, Alvarez-Garcia J, Schricker T, Jones PM, Drummond LW, Balasubramanian K, Yusuf S, Devereaux PJ. Risk of stroke and other adverse outcomes in patients with perioperative atrial fibrillation 1 year after non-cardiac surgery. Eur Heart J. 2020 February 01;41(5):645-51.


Corcoran TB, O'Loughlin E, Chan MTV, Ho KM. Perioperative ADministration of dexamethasone and blood glucose concentrations in patients undergoing elective non-cardiac surgery - the randomised controlled PADDAG trial. Eur J Anaesthesiol. 2020 August 21


Li Z, Ma J, Lin Y, Shen J, Wu Z, Chan MTV, Wu WKK. Embryonic gene expression altered by maternal exposure to air pollution in rats. Environ Sci Pollut Res Int. 2020 September 01;27(25):31699-705.


Ho IHT, Chan MTV, Wu WKK, Liu X. Spinal microglia-neuron interactions in chronic pain. J Leukoc Biol. 2020 November 01;108(5):1575-92.


El-Boghdadly K, Wong DJN, Owen R, Neuman MD, Pocock S, Carlisle JB, Johnstone C, Andruszkiewicz P, Baker PA, Biccard BM, Bryson GL, Chan MTV, Cheng MH, Chin KJ, Coburn M, Jonsson Fagerlund M, Myatra SN, Myles PS, O'Sullivan E, Pasin L, Shamim F, van Klei WA, Ahmad I. Risks to healthcare workers following tracheal intubation of patients with COVID-19: A prospective international multicentre cohort study. Anaesthesia. 2020 November 01;75(11):1437-47.


Li Z, Xu D, Chen X, Li S, Chan MTV, Wu WKK. LINC01133: An emerging tumor-associated long non-coding RNA in tumor and osteosarcoma. Environ Sci Pollut Res Int. 2020 September 01;27(26):32467-73.


Yu X, Wang M, Li L, Zhang L, Chan MTV, Wu WKK. MicroRNAs in atopic dermatitis: A systematic review. J Cell Mol Med. 2020 June 01;24(11):5966-72.


Hu W, Chan H, Lu L, Wong KT, Wong SH, Li MX, Xiao ZG, Cho CH, Gin T, Chan MTV, Wu WKK, Zhang L. Autophagy in intracellular bacterial infection. Semin Cell Dev Biol. 2020;101:41-50. Available from: https://www.sciencedirect.com/science/article/pii/S1540



2019

Ng TH, Sham KWY, Xie CM, Ng SSM, To KF, Tong JHM, Liu WYZ, Zhang L, Chan MTV, Wu WKK, Cheng CHK. Eukaryotic elongation factor-2 kinase expression is an independent prognostic factor in colorectal cancer. BMC Cancer. 2019 July 02;19(1):649-0.


Ho IHT, Liu X, Zou Y, Liu T, Hu W, Chan H, Tian Y, Zhang Y, Li Q, Kou S, Chan CS, Gin T, Cheng CHK, Wong SH, Yu J, Zhang L, Wu WKK, Chan MTV. A novel peptide interfering with proBDNF-sortilin interaction alleviates chronic inflammatory pain. Theranostics. 2019 February 28;9(6):1651-65.


Ren Z, Li Z, Li S, Sheng L, Xu D, Chen X, Wu WKK, Chan MTV, Ho J. Local infiltration with cocktail analgesics during 2 level lumbar spinal fusion surgery: Study protocol of a randomized controlled trial. Medicine (Baltimore). 2019 May 01;98(19):e15526.


Chan MTV, Wang CY, Seet E, Tam S, Lai HY, Chew EFF, Wu WKK, Cheng BCP, Lam CKM, Short TG, Hui DSC, Chung F, Postoperative Vascular Complications in Unrecognized Obstructive Sleep Apnea (POSA) Study Investigators. Association of unrecognized obstructive sleep apnea with postoperative cardiovascular events in patients undergoing major noncardiac surgery. JAMA. 2019 May 14;321(18):1788-98.


NeuroVISION Investigators. Perioperative covert stroke in patients undergoing non-cardiac surgery (NeuroVISION): A prospective cohort study. Lancet. 2019 September 21;394(10203):1022-9.


McGillion MH, Henry S, Busse JW, Ouellette C, Katz J, Choiniere M, Lamy A, Whitlock R, Pettit S, Hare J, Gregus K, Brady K, Dvirnik N, Yang SS, Parlow J, Dumerton-Shore D, Gilron I, Buckley DN, Shanthanna H, Carroll SL, Coyte PC, Ebrahim S, Isaranuwatchai W, Guerriere DN, Hoch J, Khan J, MacDermid J, Martorella G, Victor JC, Watt-Watson J, Howard-Quijano K, Mahajan A, Chan MTV, Clarke H, Devereaux PJ. Examination of psychological risk factors for chronic pain following cardiac surgery: Protocol for a prospective observational study. BMJ Open. 2019 March 01;9(2):e022995-022995.


Corcoran TB, Myles PS, Forbes AB, O'Loughlin E, Leslie K, Story D, Short TG, Chan MT, Coutts P, Sidhu J, Cheng AC, Bach LA, Ho KM, Australian and New Zealand College of Anaesthetists Clinical Trials Network (ANZCA), and the Australian Society for Infectious Diseases (ASID) Clinical Research Network. The perioperative administration of dexamethasone and infection (PADDI) trial protocol: Rationale and design of a pragmatic multicentre non-inferiority study. BMJ Open. 2019 September 06;9(9):e030402-030402.


Short TG, Campbell D, Frampton C, Chan MTV, Myles PS, Corcoran TB, Sessler DI, Mills GH, Cata JP, Painter T, Byrne K, Han R, Chu MHM, McAllister DJ, Leslie K, Australian and New Zealand College of Anaesthetists Clinical Trials Network, Balanced Anaesthesia Study Group. Anaesthetic depth and complications after major surgery: An international, randomised controlled trial. Lancet. 2019 November 23;394(10212):1907-14.


Li Z, Chen X, Xu D, Li S, Chan MTV, Wu WKK. Circular RNAs in nucleus pulposus cell function and intervertebral disc degeneration. Cell Prolif. 2019 November 01;52(6):e12704.


Chan MTV, Chung F, Postoperative Vascular Complications in Unrecognized Obstructive Sleep Apnea (POSA) Study Investigators. Unrecognized obstructive sleep apnea in patients undergoing surgery-reply. JAMA. 2019 September 24;322(12):1211-2.


Moonesinghe SR, Jackson AIR, Boney O, Stevenson N, Chan MTV, Cook TM, Lane-Fall M, Kalkman C, Neuman MD, Nilsson U, Shulman M, Myles PS, Standardised Endpoints in Perioperative Medicine-Core Outcome Measures in Perioperative and Anaesthetic Care (StEP-COMPAC) Group. Systematic review and consensus definitions for the standardised endpoints in perioperative medicine initiative: Patient-centred outcomes. Br J Anaesth. 2019 November 01;123(5):664-70.


Li KHC, Sang T, Chan C, Gong M, Liu Y, Jesuthasan A, Li G, Liu T, Lam MHS, Wu WK, Chan MTV, Liu FZ, Chen C, Ho J, Xia Y, Tse G. Anaesthesia use in catheter ablation for atrial fibrillation: A systematic review and meta-analysis of observational studies. Heart Asia. 2019 August 14;11(2):e011155,011155. eCollection 2019.


Vascular Events in Noncardiac Surgery Patients Cohort Evaluation (VISION) Study Investigators, Spence J, LeManach Y, Chan MTV, Wang CY, Sigamani A, Xavier D, Pearse R, Alonso-Coello P, Garutti I, Srinathan SK, Duceppe E, Walsh M, Borges FK, Malaga G, Abraham V, Faruqui A, Berwanger O, Biccard BM, Villar JC, Sessler DI, Kurz A, Chow CK, Polanczyk CA, Szczeklik W, Ackland G, X GA, Jacka M, Guyatt GH, Sapsford RJ, Williams C, Cortes OL, Coriat P, Patel A, Tiboni M, Belley-Cote EP, Yang S, Heels-Ansdell D, McGillion M, Parlow S, Patel M, Pettit S, Yusuf S, Devereaux PJ. Association between complications and death within 30 days after noncardiac surgery. CMAJ. 2019 July 29;191(30):E830-7.


Li Z, Ma J, Bi J, Guo H, Chan MTV, Wu WKK, Wu Z, Shen J. MicroRNA signature of air pollution exposure-induced congenital defects. J Cell Physiol. 2019 August 01;234(10):17896-904.


Chen X, Chan H, Zhang L, Liu X, Ho IHT, Zhang X, Ho J, Hu W, Tian Y, Kou S, Chan CS, Yu J, Wong SH, Gin T, Chan MTV, Sun X, Wu WKK. The phytochemical polydatin ameliorates non-alcoholic steatohepatitis by restoring lysosomal function and autophagic flux. J Cell Mol Med. 2019 June 01;23(6):4290-300.


Roshanov PS, Sheth T, Duceppe E, Tandon V, Bessissow A, Chan MTV, Butler C, Chow BJW, Khan JS, Devereaux PJ. Relationship between perioperative hypotension and perioperative cardiovascular events in patients with coronary artery disease undergoing major noncardiac surgery. Anesthesiology. 2019 May 01;130(5):756-66.


Hui DS, Chow BK, Lo T, Tsang OTY, Ko FW, Ng SS, Gin T, Chan MTV. Exhaled air dispersion during high-flow nasal cannula therapy versus CPAP via different masks. Eur Respir J. 2019 April 11;53(4):10.1183/13993003.02339,2018. Print 2019 Apr.


Garg AX, Chan MTV, Cuerden MS, Devereaux PJ, Abbasi SH, Hildebrand A, Lamontagne F, Lamy A, Noiseux N, Parikh CR, Perkovic V, Quantz M, Rochon A, Royse A, Sessler DI, Shah PJ, Sontrop JM, Tagarakis GI, Teoh KH, Vincent J, Walsh M, Yared JP, Yusuf S, Whitlock RP, SIRS Investigators. Effect of methylprednisolone on acute kidney injury in patients undergoing cardiac surgery with a cardiopulmonary bypass pump: A randomized controlled trial. CMAJ. 2019 March 04;191(9):E247-56.


Li Z, Li X, Bi J, Chan MTV, Wu WKK, Shen J. Melatonin protected against the detrimental effects of microRNA-363 in a rat model of vitamin A-associated congenital spinal deformities: Involvement of notch signaling. J Pineal Res. 2019 April 01;66(3):e12558.


Hu W, Zhang L, Li MX, Shen J, Liu XD, Xiao ZG, Wu DL, Ho IHT, Wu JCY, Cheung CKY, Zhang YC, Lau AHY, Ashktorab H, Smoot DT, Fang EF, Chan MTV, Gin T, Gong W, Wu WKK, Cho CH. Vitamin D3 activates the autolysosomal degradation function against helicobacter pylori through the PDIA3 receptor in gastric epithelial cells. Autophagy. 2019 April 01;15(4):707-25.


Konstantatos AH, Zhong T, Paul E, Tsang S, Tian S, Liu M, Liang Y, Tian Y, Qiao S, Wu WKK, Chan MTV. Effect of cultural background and healthcare environment on postoperative opioid requirement. Can J Anaesth. 2019 March 01;66(3):309-17.


Myles PS, Smith JA, Kasza J, Silbert B, Jayarajah M, Painter T, Cooper DJ, Marasco S, McNeil J, Bussieres JS, McGuinness S, Byrne K, Chan MTV, Landoni G, Wallace S, Forbes A, ATACAS investigators and the ANZCA Clinical Trials Network. Tranexamic acid in coronary artery surgery: One-year results of the aspirin and tranexamic acid for coronary artery surgery (ATACAS) trial. J Thorac Cardiovasc Surg. 2019 February 01;157(2):644,652.e9.


Myles PS, Smith JA, Kasza J, Silbert B, Jayarajah M, Painter T, Cooper DJ, Marasco S, McNeil J, Bussieres JS, McGuinness S, Chan MTV, Wallace S, Forbes A, ATACAS investigators and the ANZCA Clinical Trials Network. Aspirin in coronary artery surgery: 1-year results of the aspirin and tranexamic acid for coronary artery surgery trial. J Thorac Cardiovasc Surg. 2019 February 01;157(2):633-40.


Ho J, Li X, Zhang L, Liang Y, Hu W, Yau JCW, Chan H, Gin T, Chan MTV, Tse G, Wu WKK. Translational genomics in pancreatic ductal adenocarcinoma: A review with re-analysis of TCGA dataset. Semin Cancer Biol. 2019 April 01;55:70-7.


Li Z, Ma J, Shen J, Chan MTV, Wu WKK, Wu Z. Differentially expressed circular RNAs in air pollution-exposed rat embryos. Environ Sci Pollut Res Int. 2019 November 01;26(33):34421-9.


Li Z, Ma J, Li X, Chan MTV, Wu WKK, Wu Z, Shen J. Aberrantly expressed long non-coding RNAs in air pollution-induced congenital defects. J Cell Mol Med. 2019 November 01;23(11):7717-25.


Sun X, Ng TTH, Sham KWY, Zhang L, Chan MTV, Wu WKK, Cheng CHK. Bufalin, a traditional chinese medicine compound, prevents tumor formation in two murine models of colorectal cancer. Cancer Prev Res (Phila). 2019 October 01;12(10):653-66.



2018

Buse GL, Manns B, Lamy A, Guyatt G, Polanczyk CA,Chan MTV, Wang CY, Villar JC, Sigamani A, Sessler DI, Berwanger O, Biccard BM, Pearse R, Urrutia G, Szczeklik RW, Garutti I, Srinathan S, Malaga G, Abraham V, Chow CK, Jacka MJ, Tiboni M, Ackland G, Macneil D, Sapsford R, Leuwer M, Le Manach Y, Devereaux PJ. Troponin T monitoring to detect myocardial injury after noncardiac surgery: a cost-consequence analysis. Can J Surg. 2018;61(3):185-94.
Chan H, Zhao S, Zhang L, Ho J, Leung CCH,Wong WT, Tian Y, Liu X, Kwong TNY, Chan RCY, Yu SSB, Wang MHT, Tse G, Wong SH,Chan MTV,Wu WKK. Clostridium difficile toxin B induces autophagic cell death in colonocytes. J Cell Mol Med. 2018;22(4):2469-77.
Chan MTV, Chow BK, Lo T, Ko FW, Ng SS,Gin T, Hui DS. Exhaled air dispersion during bag-mask ventilation and sputum suctioning - Implications for infection control. Sci Rep-Uk. 2018;8.?
Graham MM, Sessler DI, Parlow JL, Biccard BM, Guyatt G, Leslie K,Chan MTV, Meyhoff CS, Xavier D, Sigamani A, Kumar PA, Mrkobrada M, Cook DJ, Tandon V, Alvarez-Garcia J, Villar JC, Painter TW, Landoni G, Fleischmann E, Lamy A, Whitlock R, Le Manach Y, Aphang-Lam M, Cata JP, Gao P, Terblanche NCS, Ramana PV, Jamieson KA, Bessissow A, Mendoza GR, Ramirez S, Diemunsch PA, Yusuf S, Devereaux PJ. Aspirin in Patients With Previous Percutaneous Coronary Intervention Undergoing Noncardiac Surgery. Ann Intern Med. 2018;168(4):237-+.

?Kwong TNY, Wang XS, Nakatsu G, Chow TC, Tipoe T, Dai RZW, Tsoi KKK, Wong MCS, Tse G,Chan MTV, Chan FKL, Ng SC, Wu JCY,Wu WKK, Yu J, Sung JJY, Wong SH. Association Between Bacteremia From Specific Microbes and Subsequent Diagnosis of Colorectal Cancer. Gastroenterology. 2018;155(2):383-+.?
Li XC, Xu WQ, Kang W, Wong SH, Wang MY, Zhou Y, Fang XD, Zhang XQ, Yang HM, Wong CH, To KF, Chan SL,Chan MTV, Sung JJY,Wu WKK, Yu J. Genomic analysis of liver cancer unveils novel driver genes and distinct prognostic features. Theranostics. 2018;8(6):1740-51.
Li Z, Chen C, Lin YX, Li XY, Tan HN,Chan MTV,Wu WKK, Zhan ST, Cao Q, Shen JX. A novel probe for measuring tissue bioelectrical impedance to enhance pedicle screw placement in spinal surgery. Am J Transl Res. 2018;10(7):2205-12.
Li Z, Jiang C, Li XY,Wu WKK, Chen X, Zhu SB, Ye CH,Chan MTV, Qian WW. Circulating microRNA signature of steroid-induced osteonecrosis of the femoral head. Cell Proliferat. 2018;51(1).
Li Z, Li XY, Jiang C, Qian WW, Tse G,Chan MTV,Wu WKK. Long non-coding RNAs in rheumatoid arthritis. Cell Proliferat. 2018;51(1).
Li Z, Shen JX,Chan MTV,Wu WKK. The long non-coding RNA SPRY4-IT1: An emerging player in tumorigenesis and osteosarcoma. Cell Proliferat. 2018;51(4).
Li Z, Yang B, Weng XS, Tse G,Chan MTV,Wu WKK. Emerging roles of MicroRNAs in osteonecrosis of the femoral head. Cell Proliferat. 2018;51(1).
Lindroth H, Bratzke L, Purvis S, Brown R, Coburn M, Mrkobrada M,Chan MTV, Davis DHJ, Pandharipande P, Carlsson CM, Sanders RD. Systematic review of prediction models for delirium in the older adult inpatient. Bmj Open. 2018;8(4).?
Myles PS, Bellomo R, Corcoran T, Forbes A, Peyton P, Story D, Christophi C, Leslie K, McGuinness S, Parke R, Serpell J,Chan MTV, Painter T, McCluskey S, Minto G, Wallace S, Anaes ANZC, C ANZI. Restrictive versus Liberal Fluid Therapy for Major Abdominal Surgery. New Engl J Med. 2018;378(24):2263-74.
Myles PS, Smith JA, Forbes A, Silbert B, Jayarajah M, Painter T, Cooper J, Marasco S, McNeil J, Bussieres JS, McGuinness S, Byrne K,Chan MTV, Landoni G, Wallace S, Network ACT. Tranexamic Acid in Patients Undergoing Coronary-Artery Surgery (vol 376, pg 136, 2017). New Engl J Med. 2018;378(8):782-.
Nakatsu G, Zhou HK,Wu WKK, Wong SH, Coker OO, Dai ZW, Li XC, Szeto CH, Sugimura N, Lam TYT, Yu ACS, Wang XS, Chen ZG, Wong MCS, Ng SC,Chan MTV, Chan PKS, Chan FKL, Sung JJY, Yu J. Alterations in Enteric Virome Are Associated With Colorectal Cancer and Survival Outcomes. Gastroenterology. 2018;155(2):529-+.
Tian Y, Liu X, Jia M, Yu H, Lichtner P, Shi Y, Meng Z, Kou S, Ho IHT, Jia B, Cheng BCP, Lam CKM, Tsang S, Wong SH, Yu J, Cheng CHK,Gin T,Wu WKK, Chen Z,Chan MTV. Targeted Genotyping Identifies Susceptibility Locus in Brain-derived Neurotrophic Factor Gene for Chronic Postsurgical Pain (vol 128, pg 587, 2018). Anesthesiology. 2018;128(5):1049-.
Tian YY, Liu XD, Jia MZ, Yu H, Lichtner P, Shi YJ, Meng ZY, Kou SL, Ho IHT, Jia B, Cheng BCP, Lam CKM, Tsang S, Wong SH, Yu J, Cheng CHK,Gin T,Wu WKK, Chen ZY,Chan MTV, Stud PPAS. Targeted Genotyping Identifies Susceptibility Locus in Brain-derived Neurotrophic Factor Gene for Chronic Postsurgical Pain. Anesthesiology. 2018;128(3):587-97.
Tipoe TL,Wu WKK, Chung L, Gong MQ, Dong M, Liu T, Roever L, Ho J, Wong MCS,Chan MTV, Tse G, Wu JCY, Wong SH. Plasminogen Activator Inhibitor 1 for Predicting Sepsis Severity and Mortality Outcomes: A Systematic Review and Meta-Analysis. Front Immunol. 2018;9.
Wang XJ, Zhang X, Chu ESH, Chen XT, Kang W, Wu F, To KF, Wong VWS, Chan HLY,Chan MTV, Sung JJY,Wu WKK, Yu J. Defective lysosomal clearance of autophagosomes and its clinical implications in nonalcoholic steatohepatitis. Faseb J. 2018;32(1):37-51.
Wong WT, Phua J,Joynt GM. Worldwide end-of-life practice for patients in ICUs. Curr Opin Anesthesio. 2018;31(2):172-8.
Wu WKK, Sun R, Zuo T, Tian YY, Zeng ZR, Ho J, Wu JCY, Chan FKL,Chan MTV, Yu J, Sung JJY, Wong SH, Wang MH, Ng SC. A novel susceptibility locus in MST1 and gene-gene interaction network for Crohn's disease in the Chinese population. J Cell Mol Med. 2018;22(4):2368-77.
Yu X, Zheng HY,Chan MTV,Wu WKK. Immune consequences induced by photodynamic therapy in non-melanoma skin cancers: a review. Environ Sci Pollut R. 2018;25(21):20569-74.
Yu X, Zheng HY,Chan MTV,Wu WKK. NOVA1 acts as an oncogene in melanoma via regulating FOXO3a expression. J Cell Mol Med. 2018;22(5):2622-30.
Yu X, Zheng HY, Tse G,Chan MTV,Wu WKK. Long non-coding RNAs in melanoma. Cell Proliferat. 2018;51(4).
Zhang L, Hu W, Cho CH, Chan FKL, Yu J, Fitzgerald JR, Cheung CKY, Xiao ZG, Shen J, Li LF, Li MX, Wu JCY, Ling TKW, Chan JYK, Ko H, Tse G, Ng SC, Yu S, Wang MHT,Gin T, Ashktorab H, Smoot DT, Wong SH,Chan MTV,Wu WKK. Reduced lysosomal clearance of autophagosomes promotes survival and colonization of Helicobacter pylori. J Pathol. 2018;244(4):432-44.
Zhang L, Zhang YC, Wong SH, Law PTY, Zhao S, Yu J,Chan MTV,Wu WKK. Common Deregulation of Seven Biological Processes by MicroRNAs in Gastrointestinal Cancers. Sci Rep-Uk. 2018;8.



2017

Chan MTV, Chu MHM, Lam CKM, Jia B, Tsang S,Wu WKK. Deep anesthesia: too much of a good thing? Can J Anesth. 2017;64(6):574-80.
Corcoran T, Kasza J, Short TG, O'Loughlin E,Chan MTV, Leslie K, Forbes A, Paech M, Myles P, Investigators E-I. Intraoperative dexamethasone does not increase the risk of postoperative wound infection: a propensity score-matched post hoc analysis of the ENIGMA-II trial (EnDEX). Brit J Anaesth. 2017;118(2):190-9.
Ho AMH, Leung JYC, Mizubuti GB, Contardi LH,Chan MTV, Lo TSF,Lee AKT. Inattentional blindness in anesthesiology: A simulation study. J Clin Anesth. 2017;42:36-9.
Ho J, He WJ,Chan MTV, Tse G, Liu T, Wong SH,Leung CCH, Wong WT, Tsang S, Zhang L, Chan RYP,Gin T, Leung J, Lau BWM,Wu WKK, Ngai SPC. Eosinophilia and clinical outcome of chronic obstructive pulmonary disease: a meta-analysis. Sci Rep-Uk. 2017;7.
Ho J, Zhang L, Liu XD, Wong SH, Wang MHT, Lau BWM, Ngai SPC, Chan H, Choi G,Leung CCH, Wong WT, Tsang S,Gin T, Yu J,Chan MTV,Wu WKK. Pathological Role and Diagnostic Value of Endogenous Host Defense Peptides in Adult and Neonatal Sepsis: A Systematic Review. Shock. 2017;47(6):673-9.
Li Z, Li XY,Chan MTV,Wu WKK, Tan DX, Shen JX. Melatonin antagonizes interleukin-18-mediated inhibition on neural stem cell proliferation and differentiation. J Cell Mol Med. 2017;21(9):2163-71.
Li Z, Li XY, Chen C,Chan MTV,Wu WKK, Shen JX. Melatonin inhibits nucleus pulposus (NP) cell proliferation and extracellular matrix (ECM) remodeling via the melatonin membrane receptors mediated PI3K-Akt pathway. J Pineal Res. 2017;63(3).
Li Z, Shen JX,Chan MTV,Wu WKK. The role of microRNAs in intrahepatic cholangiocarcinoma. J Cell Mol Med. 2017;21(1):177-84.
Li Z, Shen JX,Chan MTV,Wu WKK. MicroRNA-379 suppresses osteosarcoma progression by targeting PDK1. J Cell Mol Med. 2017;21(2):315-23.
Liu QM, Wang QZ, Liu HG,Wu WKK,Chan MTV. Warning criteria for intraoperative neurophysiologic monitoring. Curr Opin Anesthesio. 2017;30(5):557-62.
Liu Y, Zhu ZY, Ho IHT, Shi YJ, Xie YX, Li JZ, Zhang Y,Chan MTV, Cheng CHK. Germline-specific dgcr8 knockout in zebrafish using a BACK approach. Cell Mol Life Sci. 2017;74(13):2503-11.
Myles PS, Smith JA, Forbes A, Silbert B, Jayarajah M, Painter T, Cooper DJ, Marasco S, McNeil J, Bussieres JS, McGuinness S, Byrne K,Chan MTV, Landoni G, Wallace S, Network ACT. Tranexamic Acid in Patients Undergoing Coronary-Artery Surgery. New Engl J Med. 2017;376(2):136-48.
Peng YM, Li Y, Jian MY, Liu XY, Sun J, Jia B, Dong J, Zeng M, Lin N, Zhang L, Gelb AW,Chan MTV, Han RQ. Choice of ANesthesia for EndoVAScular Treatment of Acute Ischemic Stroke: Protocol for a randomized controlled (CANVAS) trial. Int J Stroke. 2017;12(9):991-7.
Wu WKK, Li XC, Wang XS, Dai RZW, Cheng ASL, Wang MHT, Kwong T, Chow TC, Yu J,Chan MTV, Wong SH. Oncogenes without a Neighboring Tumor-Suppressor Gene Are More Prone to Amplification. Mol Biol Evol. 2017;34(4):903-7.
Xin Y,Li Z, Zheng HY,Chan MTV,Wu WKK. CCAT2: A novel oncogenic long non-coding RNA in human cancers. Cell Proliferat. 2017;50(3).
Xin Y,Li Z, Zheng HY, Ho J,Chan MTV,Wu WKK. Neuro-oncological ventral antigen 1 (NOVA1): Implications in neurological diseases and cancers. Cell Proliferat. 2017;50(4).
Yu X,Li Z, Zheng HY,Chan MTV,Wu WKK. NEAT1: A novel cancer-related long non-coding RNA. Cell Proliferat. 2017;50(2).
Yu X,Li Z, Zheng HY, Ho J,Chan MTV,Wu WKK. Protective roles of melatonin in central nervous system diseases by regulation of neural stem cells. Cell Proliferat. 2017;50(2).
Yu X, Zheng HY,Chan MTV,Wu WKK. MicroRNAs: new players in cataract. Am J Transl Res. 2017;9(9):3896-903.
Yu X, Zheng HY,Chan MTV,Wu WKK. Modulation of chemoresponsiveness to platinum-based agents by microRNAs in cancer. Am J Cancer Res. 2017;7(9):1769-78.
Yu X, Zheng HY,Chan MTV,Wu WKK. BANCR: a cancer-related long non-coding RNA. Am J Cancer Res. 2017;7(9):1779-87.
Yu X, Zheng HY,Chan MTV,Wu WKK. HULC: an oncogenic long non-coding RNA in human cancer. J Cell Mol Med. 2017;21(2):410-7.



2016

Bai AHC,Wu WKK, Xu LL, Wong SH, Go MY, Chan AWH, Harbord M, Zhang SH, Chen MH, Wu JCY, Chan MWY,Chan MTV, Chan FKL, Sung JJY, Yu J, Cheng ASL, Ng SC. Dysregulated Lysine Acetyltransferase 2B Promotes Inflammatory Bowel Disease Pathogenesis Through Transcriptional Repression of Interleukin-10. J Crohns Colitis. 2016;10(6):726-34.
Chan MTV, Peyton PJ, Myles PS, Leslie K, Buckley N, Kasza J, Paech MJ, Beattie WS, Sessler DI, Forbes A, Wallace S, Chen Y, Tian Y,Wu WKK, Coll ANZ. Chronic postsurgical pain in the Evaluation of Nitrous Oxide in the Gas Mixture for Anaesthesia (ENIGMA)-II trial. Brit J Anaesth. 2016;117(6):801-11.
Ho J, Chan H, Wong SH, Wang MHT, Yu J, Xiao ZG, Liu XD, Choi G, Leung CCH, Wong WT, Li Z,Gin T,Chan MTV,Wu WKK. The involvement of regulatory non-coding RNAs in sepsis: a systematic review. Crit Care. 2016;20.
Ho J, Yu J, Wong SH, Zhang L, Liu XD, Wong WT, Leung CCH, Choi G, Wang MHT,Gin T,Chan MTV,Wu WKK. Autophagy in sepsis: Degradation into exhaustion? Autophagy. 2016;12(7):1073-82.
13. Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Arozena AA, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, Agnello M, Agostinis P, Aguilar PV, Aguirre-Ghiso J, Airoldi EM, Ait-Si-Ali S, Akematsu T, Akporiaye ET, Al-Rubeai M, Albaiceta GM, Albanese C, Albani D, Albert ML, Aldudo J, Algul H, Alirezaei M, Alloza I, Almasan A, Almonte-Beceril M, Alnemri ES, Alonso C, Altan-Bonnet N, Altieri DC, Alvarez S, Alvarez-Erviti L, Alves S, Amadoro G, Amano A, Amantini C, Ambrosio S, Amelio I, Amer AO, Amessou M, Amon A, An ZY, Anania FA, Andersen SU, Andley UP, Andreadi CK, Andrieu-Abadie N, Anel A, Ann DK, Anoopkumar-Dukie S, Antonioli M, Aoki H, Apostolova N, Aquila S, Aquilano K, Araki K, Arama E, Aranda A, Araya J, Arcaro A, Arias E, Arimoto H, Ariosa AR, Armstrong JL, Arnould T, Arsov I, Asanuma K, Askanas V, Asselin E, Atarashi R, Atherton SS, Atkin JD, Attardi LD, Auberger P, Auburger G, Aurelian L, Autelli R, Avagliano L, Avantaggiati ML, Avrahami L, Awale S, Azad N, Bachetti T, Backer JM, Bae DH, Bae JS, Bae ON, Bae SH, Baehrecke EH, Baek SH, Baghdiguian S, Bagniewska-Zadworna A, Bai H, Bai J, Bai XY, Bailly Y, Balaji KN, Balduini W, Ballabio A, Balzan R, Banerjee R, Banhegyi G, Bao HJ, Barbeau B, Barrachina MD, Barreiro E, Bartel B, Bartolome A, Bassham DC, Bassi MT, Bast RC, Basu A, Batista MT, Batoko H, Battino M, Bauckman K, Baumgarner BL, Bayer KU, Beale R, Beaulieu JF, Beck GR, Becker C, Beckham JD, Bedard PA, Bednarski PJ, Begley TJ, Behl C, Behrends C, Behrens GMN, Behrns KE, Bejarano E, Belaid A, Belleudi F, Benard G, Berchem G, Bergamaschi D, Bergami M, Berkhout B, Berliocchi L, Bernard A, Bernard M, Bernassola F, Bertolotti A, Bess AS, Besteiro S, Bettuzzi S, Bhalla S, Bhattacharyya S, Bhutia SK, Biagosch C, Bianchi MW, Biard-Piechaczyk M, Billes V, Bincoletto C, Bingol B, Bird SW, Bitoun M, Bjedov I, Blackstone C, Blanc L, Blanco GA, Blomhoff HK, Boada-Romero E, Bockler S, Boes M, Boesze-Battaglia K, Boise LH, Bolino A, Boman A, Bonaldo P, Bordi M, Bosch J, Botana LM, Botti J, Bou G, Bouche M, Bouchecareilh M, Boucher MJ, Boulton ME, Bouret SG, Boya P, Boyer-Guittaut M, Bozhkov PV, Brady N, Braga VMM, Brancolini C, Braus GH, Bravo-San Pedro JM, Brennan LA, Bresnick EH, Brest P, Bridges D, Bringer MA, Brini M, Brito GC, Brodin B, Brookes PS, Brown EJ, Brown K, Broxmeyer HE, Bruhat A, Brum PC, Brumell JH, Brunetti-Pierri N, Bryson-Richardson RJ, Buch S, Buchan AM, Budak H, Bulavin DV, Bultman SJ, Bultman SJ, Bumbasirevic V, Burelle Y, Burke RE, Burmeister M, Butikofer P, Caberlotto L, Cadwell K, Cahova M, Cai DS, Cai JJ, Cai Q, Calatayud S, Camougrand N, Campanella M, Campbell GR, Campbell M, Campello S, Candau R, Caniggia I, Cantoni L, Cao LZ, Caplan AB, Caraglia M, Cardinali C, Cardoso SM, Carew JS, Carleton LA, Carlin CR, Carloni S, Carlsson SR, Carmona-Gutierrez D, Carneiro LAM, Carnevali O, Carra S, Carrier A, Carroll B, Casas C, Casas J, Cassinelli G, Castets P, Castro-Obregon S, Cavallini G, Ceccherini I, Cecconi F, Cederbaum AI, Cena V, Cenci S, Cerella C, Cervia D, Cetrullo S, Chaachouay H, Chae HJ, Chagin AS, Chai CY, Chakrabarti G, Chamilos G, Chan EYW,Chan MTV,et al.. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 2016;12(1):1-222.
Konstantatos AH, Howard W, Story D, Mok LYH, Boyd D,Chan MTVA randomised controlled trial of peri-operative pregabalin vs. placebo for video-assisted thoracoscopic surgery. Anaesthesia. 2016;71(2):192-7.
Lei DW, Dong CG,Wu WKK, Dong AM, Li TT,Chan MTV, Zhou XR, Yuan HP. Lentiviral Delivery of Small Hairpin RNA Targeting Connective Tissue Growth Factor Blocks Profibrotic Signaling in Tenon's Capsule Fibroblasts. Invest Ophth Vis Sci. 2016;57(13):5171-80.
Li XC,Wu WKK, Xing R, Wong SH, Liu YX, Fang XD, Zhang YL, Wang MY, Wang JQ, Li L, Zhou Y, Tang SW, Peng SL, Qiu KL, Chen LY, Chen KX, Yang HM, Zhang W,Chan MTV, Lu YY, Sung JJY, Yu J. Distinct Subtypes of Gastric Cancer Defined by Molecular Characterization Include Novel Mutational Signatures with Prognostic Capability. Cancer Res. 2016;76(7):1724-32.
Li Z, Shen JX,Chan MTV,Wu WKK. TUG1: a pivotal oncogenic long non-coding RNA of human cancers. Cell Proliferat. 2016;49(4):471-5.
Li Z, Wong SH, Shen JX,Chan MTV,Wu WKK. The Role of MicroRNAS in Ankylosing Spondylitis. Medicine. 2016;95(14).
Mrkobrada M, Hill MD,Chan MTV, Sigamani A, Cowan D, Kurz A, Sessler DI, Jacka M, Graham M, Dasgupta M, Dunlop V, Emery DJ, Gulka I, Guyatt G, Heels-Ansdell D, Murkin J, Pettit S, Sahlas DJ, Sharma M, Sharma M, Srinathan S, St John P, Tsai S, Gelb AW, O'Donnell M, Siu D, Chiu PWY, Sharath V, George A, Devereaux PJ. Covert stroke after non-cardiac surgery: a prospective cohort study. Brit J Anaesth. 2016;117(2):191-7.
Myles PS,Chan MTV, Kasza J, Paech MJ, Leslie K, Peyton PJ, Sessler DI, Haller G, Beattie WS, Osborne C, Sneyd JR, Forbes A. Severe Nausea and Vomiting in the Evaluation of Nitrous Oxide in the Gas Mixture for Anesthesia II Trial. Anesthesiology. 2016;124(5):1032-40.
Sun Z, Yue Y, Leung CCH,Chan MTV, Gelb AW, Stroke SGP. Clinical diagnostic tools for screening of perioperative stroke in general surgery: a systematic review. Brit J Anaesth. 2016;116(3):328-38.
Tang SW,Wu WKK, Li XC, Wong SH, Wong N,Chan MTV, Sung JJY, Yu J. Stratification of Digestive Cancers with Different Pathological Features and Survival Outcomes by MicroRNA Expression. Sci Rep-Uk. 2016;6.
Tsang DPF,Wu WKK, Kang W, Lee YY, Wu F, Yu Z, Xiong L, Chan AW, Tong JH, Yang WQ, Li MSM, Lau SS, Li XC, Lee SD, Yang YH, Lai PBS, Yu DY, Xu G, Lo KW,Chan MTV, Wang HT, Lee TL, Yu J, Wong N, Yip KY, To KF, Cheng ASL. Yin Yang 1-mediated epigenetic silencing of tumour-suppressive microRNAs activates nuclear factor-B in hepatocellular carcinoma. J Pathol. 2016;238(5):651-64.
Wu WKK,Chan MTV, Cheng ASL. A transcriptional-microRNA network for beta-catenin-driven stemness in hepatocellular carcinoma. Transl Cancer Res. 2016;5:S1408-S12.
Wu WKK, Yu J,Chan MTV, To KF, Cheng ASL. Combinatorial epigenetic deregulation by Helicobacter pylori and Epstein-Barr virus infections in gastric tumourigenesis. J Pathol. 2016;239(3):245-9.
Xin Y, Li Z,Chan MTV,Wu WKK. Circulating epigenetic biomarkers in melanoma. Tumor Biol. 2016;37(2):1487-92.
Xin Y, Li Z, Shen JX,Chan MTV,Wu WKK. CCAT1: a pivotal oncogenic long non-coding RNA in human cancers. Cell Proliferat. 2016;49(3):255-60.
Yu J,Wu WKK, Liang Q, Zhang N, He J, Li X, Zhang X, Xu L,Chan MTV, Ng SSM, Sung JJY. Disruption of NCOA2 by recurrent fusion with LACTB2 in colorectal cancer. Oncogene. 2016;35(2):187-95.
Yu L,Wu WKK, Gu CP, Zhong DS, Zhao XY, Kong Y, Lin QH,Chan MTV, Zhou ZT, Liu SW. Obatoclax impairs lysosomal function to block autophagy in cisplatin-sensitive and -resistant esophageal cancer cells. Oncotarget. 2016;7(12):14693-707.
Yu X, Li Z,Chan MTV,Wu WKK. The roles of microRNAs in Wilms' tumors. Tumor Biol. 2016;37(2):1445-50.
Yu X, Li Z, Shen JX,Chan MTV,Wu WKK. Role of microRNAs in primary central nervous system lymphomas. Cell Proliferat. 2016;49(2):147-53.
Zhang L,Wu WKK, Gallo RL, Fang EF, Hu W, Ling TKW, Shen J, Chan RLY, Lu L, Luo XM, Li MX, Chan KM, Yu J, Wong VWS, Ng SC, Wong SH, Chan FKL, Sung JJY,Chan MTV, Cho CH. Critical Role of Antimicrobial Peptide Cathelicidin for Controlling Helicobacter pylori Survival and Infection. J Immunol. 2016;196(4):1799-809.





2015

Chan MTV,Gin T. Delirium and cognitive decline after surgery: a randomised controlled trial of anaesthetic management to improve postoperative mental health outcome. Hong Kong Med J 2015; 20 Suppl 7; 28-9.


Chan MTV,Gin T. Predicting postoperative cardiac complications using automated endothelial function test. Hong Kong Med J 2015; 21 Suppl 6; 17-8.
Chan MTV,Wu WKK, Tang RS. Optimizing depth of sedation for colonoscopy. Can J Anaesth 2015; 62(11); 1143-8. doi: 10.1007/s12630-015-0462-4.
Chen X, Dong C, Law PT,Chan MTV, Su Z, Wang S,Wu WKK, Xu H. MicroRNA-145 targets TRIM2 and exerts tumor-suppressing functions in epithelial ovarian cancer. Gynecol Oncol 2015; 139(3); 513-9. doi: 10.1016/j.ygyno.2015.10.008.
Dorhout Mees SM, Algra A, Wong GK, Poon WS, Bradford CM, Saver JL, Starkman S, Rinkel GJ, van den Bergh WM; writing groups of MASH-I, IMASH, MASH-II, MASH and FAST-MAG, van Kooten F, Dirven CM, van Gijn J, Vermeulen M, Rinkel GJ, Boet R,Chan MTV,Gin T, Ng SC, Zee BC, Al-Shahi Salman R, Boiten J, Kuijsten H, Lavados PM, van Oostenbrugge RJ, Vandertop WP, Finfer S, O'Connor A, Yarad E, Firth R, McCallister R, Harrington T, Steinfort B, Faulder K, Assaad N, Morgan M, Starkman S, Eckstein M, Stratton SJ, Pratt FD, Hamilton S, Conwit R, Liebeskind DS, Sung G, Kramer I, Moreau G, Goldweber R, Sanossian N. Early Magnesium Treatment After Aneurysmal Subarachnoid Hemorrhage: Individual Patient Data Meta-Analysis. Stroke 2015; 46(11); 3190-3. doi: 10.1161/STROKEAHA.115.010575.
Hui DS, Chow BK, Lo T, Ng SS, Ko FW,Gin T,Chan MTV. Exhaled air dispersion during noninvasive ventilation via helmets and a total facemask. Chest 2015; 147(5); 1336-43. doi: 10.1378/chest.14-1934.?

Leslie K, Myles PS, Kasza J, Forbes A, Peyton PJ,Chan MTV, Paech MJ, Sessler DI, Beattie WS, Devereaux PJ, Wallace S. Nitrous Oxide and Serious Long-term Morbidity and Mortality in the Evaluation of Nitrous Oxide in the Gas Mixture for Anaesthesia (ENIGMA)-II Trial. Anesthesiology 2015; 123(6); 1267-80. doi: 10.1097/ALN.0908.
Leung JY,Critchley LAH, Yung AL, Kumta SM. Evidence of virtual patients as a facilitative learning tool on an anesthesia course. Adv Health Sci Educ Theory Pract 2015; 20(4); 885-901. doi: 10.1007/s10459-014-9570-0.
Li CW, Liao CH, Huang X,Chan MTV. Orchids (Oncidium and Phalaenopsis). Methods Mol Biol 2015; 1224; 331-46. doi: 10.1007/978-1-4939-1658-0_26.
Li H,Critchley LAH, Zhang J. Does using two Doppler cardiac output monitors in tandem provide a reliable trend line of changes for validation studies? J Clin Monit Comput 2015.
Li X, Li JW, Ho AM,Karmakar MK. Age-related differences in the quantitative echo texture of the median nerve. J Ultrasound Med 2015; 34(5); 797-804. doi: 10.7863/ultra.34.5.797.
Li Z, Shen J, Li Q,Chan MTV,Wu WKK. Drug Fever Induced by Piperacillin/Tazobactam in a Scoliosis Patient: A Case Report. Medicine (Baltimore) 2015; 94(46); e1875. doi: 10.1097/MD.1875.
Li Z, Yu X, Shen J,Chan MTV,Wu WKK. MicroRNA in intervertebral disc degeneration. Cell Prolif 2015; 48(3); 278-83. doi: 10.1111/cpr.12180.
Li Z, Yu X, Shen J, Law PT,Chan MTV,Wu WKK. MicroRNA expression and its implications for diagnosis and therapy of gallbladder cancer. Oncotarget 2015; 6(16); 13914-21.
Li Z, Yu X, Shen J, Liu Y,Chan MTV,Wu WKK. MicroRNA dysregulation in rhabdomyosarcoma: a new player enters the game. Cell Prolif 2015; 48(5); 511-6. doi: 10.1111/cpr.12199.
Li Z, Yu X, Shen J,Wu WKK,Chan MTV. MicroRNA expression and its clinical implications in Ewing's sarcoma. Cell Prolif; 48(1); 1-6. doi: 10.1111/cpr.12160.
Li Z, Yu X, Wang Y, Shen J,Wu WKK, Liang J, Feng F. By downregulating TIAM1 expression, microRNA-329 suppresses gastric cancer invasion and growth. Oncotarget 2015; 6(19); 17559-69.
Lin CS, Chen JJ, Huang YT,Chan MTV, Daniell H, Chang WJ, Hsu CT, Liao DC, Wu FH, Lin SY, Liao CF, Deyholos MK, Wong GK, Albert VA, Chou ML, Chen CY, Shih MC. The location and translocation of ndh genes of chloroplast origin in the Orchidaceae family. Sci Rep 2015; 5; 9040. doi: 10.1038/srep09040.
Liu X, Dong C, Jiang Z,Wu WKK,Chan MTV, Zhang J, Li H, Qin K, Sun X. MicroRNA-10b downregulation mediates acute rejection of renal allografts by derepressing BCL2L11. Exp Cell Res 2015; 333(1); 155-63. doi: 10.1016/j.yexcr.2015.01.018.
Liu X, Tian Y, Meng Z, Chen Y, Ho IH, Choy KW, Lichtner P, Wong SH, Yu J,Gin T,Wu WKK, Cheng CH,Chan MTV. Up-regulation of Cathepsin G in the Development of Chronic Postsurgical Pain: An Experimental and Clinical Genetic Study. Anesthesiology; 123(4); 838-50. doi: 10.1097/ALN.0828.
Lu L, Li ZJ, Li LF,Wu WKK, Shen J, Zhang L, Chan RL, Yu L, Liu YW, Ren SX, Chan KM, Cho CH. Vascular-targeted TNFa improves tumor blood vessel function and enhances antitumor immunity and chemotherapy in colorectal cancer. J Control Release 2015; 210; 134-46. doi: 10.1016/j.jconrel.2015.05.282.
Luo MX, Wong SH,Chan MTV, Yu L, Yu SS, Wu F, Xiao Z, Wang X, Zhang L, Cheng AS, Ng SS, Chan FK, Cho CH, Yu J, Sung JJ,Wu WKK. Autophagy Mediates HBx-Induced Nuclear Factor-?B Activation and Release of IL-6, IL-8, and CXCL2 in Hepatocytes. J Cell Physiol 2015; 230(10); 2382-9. doi: 10.1002/jcp.24967.
McIlroy DR,Chan MTV, Wallace SK, Grover A, Koo EG, Ma J, Symons JA, Myles PS. Is Preoperative Endothelial Dysfunction a Potentially Modifiable Risk Factor for Renal Injury Associated With Noncardiac Surgery? J Cardiothorac Vasc Anesth 2015; 29(5); 1220-8. doi: 10.1053/j.jvca.2015.05.116.
Moralli D, Nudel R,Chan MTV, Green CM, Volpi EV, Benítez-Burraco A, Newbury DF, García-Bellido P. Language impairment in a case of a complex chromosomal rearrangement with a breakpoint downstream of FOXP2. Mol Cytogenet 2015; 8; 36. doi: 10.1186/s13039-015-0148-1.
Myles PS, Peyton P,Chan MTV, Leslie K; ENIGMA-II investigators. Nitrous oxide in general anaesthesia - Authors' reply. Lancet 2015; 385(9966); 417-8. doi: 10.1016/S0140-6736(15)60152-0.?
Ruhlman TA, Chang WJ, Chen JJ, Huang YT,Chan MTV, Zhang J, Liao DC, Blazier JC, Jin X, Shih MC, Jansen RK, Lin CS. NDH expression marks major transitions in plant evolution and reveals coordinate intracellular gene loss. BMC Plant Biol 2015; 15; 100. doi: 10.1186/s12870-015-0484-7.
Shen J, Xiao Z,Wu WKK, Wang MH, To KF, Chen Y, Yang W, Li MS, Shin VY, Tong JH, Kang W, Zhang L, Li M, Wang L, Lu L, Chan RL, Wong SH, Yu J,Chan MTV, Chan FK, Sung JJ, Cheng AS, Cho CH. Epigenetic silencing of miR-490-3p reactivates the chromatin remodeler SMARCD1 to promote Helicobacter pylori-induced gastric carcinogenesis. Cancer Res 2015; 75(4); 754-65. doi: 10.1158/0008-5472.CAN-14-1301.
Short TG, Leslie K,Chan MTV, Campbell D, Frampton C, Myles P. Rationale and Design of the Balanced Anesthesia Study: A Prospective Randomized Clinical Trial of Two Levels of Anesthetic Depth on Patient Outcome After Major Surgery. Anesth Analg 2015; 121(2); 357-65. doi: 10.1213/ANE.0797.
Shulman MA, Myles PS,Chan MTV, McIlroy DR, Wallace S, Ponsford J. Measurement of disability-free survival after surgery. Anesthesiology 2015; 122(3); 524-36. doi: 10.1097/ALN.0586.
Wong GK, Chan DY, Siu DY, Zee BC, Poon WS,Chan MTV,Gin T, Leung M; HDS-SAH Investigators. High-dose simvastatin for aneurysmal subarachnoid hemorrhage: multicenter randomized controlled double-blinded clinical trial. Stroke; 46(2); 382-8. doi: 10.1161/STROKEAHA.114.007006.
Wong GK, Wong A, Zee BC, Poon WS,Chan MTV,Gin T, Siu DY, Mok VC. Cognitive outcome in acute simvastatin treatment for aneurysmal subarachnoid hemorrhage: A propensity matched analysis. J Neurol Sci. 2015; 358(1-2); 58-61. doi: 10.1016/j.jns.2015.08.013.
Wong WT, Choi G,Gomersall CD, Lipman J. To increase or decrease dosage of antimicrobials in septic patients during continuous renal replacement therapy: the eternal doubt. Curr Opin Pharmacol 2015; 24; 68-78. doi: 10.1016/j.coph.2015.07.003. Epub 2015 Oct 28.
Xin Y, Li Z,Chan MTV,Wu WKK. Circulating epigenetic biomarkers in melanoma. Tumour Biol 2015.
Yu X, Li Z,Chan MTV,Wu WKK. microRNA deregulation in keloids: an opportunity for clinical intervention? Cell Prolif; 48(6); 626-30. doi: 10.1111/cpr.12225.
Yu X, Li Z,Chan MTV,Wu WKK. PAQR3: a novel tumor suppressor gene. Am J Cancer Res 2015; 5(9); 2562-8.
Yu X, Li Z,Chan MTV,Wu WKK. The roles of microRNAs in Wilms' tumors. Tumour Biol 2015.
Yu X, Li Z, Yu J,Chan MTV,Wu WKK. MicroRNAs predict and modulate responses to chemotherapy in colorectal cancer. Cell Prolif 2015; 48(5); 503-10. doi: 10.1111/cpr.12202.




2014

Chan MTV, Gin T. "Delirium and cognitive decline after surgery: a randomised controlled trial of anaesthetic management to improve postoperative mental health outcome." Hong Kong Med J. 2014 Dec. 28-29.


Garg AX, Kurz A, Sessler DI, Cuerden M, Robinson A, Mrkobrada M, Parikh CR, Mizera R, Jones PM, Tiboni M, Font A, Cegarra V, Gomez MF, Meyhoff CS, VanHelder T, Chan MTV, Torres D, Parlow J, Clanchet Mde N, Amir M, Bidgoli SJ, Pasin L, Martinsen K, Malaga G, Myles P, Acedillo R, Roshanov PS, Walsh M, Dresser G, Kumar P, Fleischmann E, Villar JC, Painter T, Biccard B, Bergese S, Srinathan S, Cata JP, Chan V, Mehra B, Wijeysundera DN, Leslie K, Forget P, Whitlock R, Yusuf S, Devereaux PJ; POISE-2 Investigators. "Perioperative aspirin and clonidine and risk of acute kidney injury: a randomized clinical trial." JAMA. 2014 Dec 3. 2254-2264.

Hui DS, Chow BK, Lo T, Ng S, Ko FW, Gin T, Chan MTV. "Exhaled air dispersion during non-invasive ventilation via helmets and a total facemask." Chest. 2014 Nov 13. 14-1934.

Hui DS, Chan MTV, Chow B. "Aerosol dispersion during various respiratory therapies: a risk assessment model of nosocomial infection to health care workers." Hong Kong Med J. 2014 Aug. 9-13.
Myles PS, Leslie K, Chan MTV, Forbes A, Peyton PJ, Paech MJ, Beattie WS, Sessler DI, Devereaux PJ, Silbert B, Schricker T, Wallace S; ANZCA Trials Group for the ENIGMA-II investigators. "The safety of addition of nitrous oxide to general anaesthesia in at-risk patients having major non-cardiac surgery (ENIGMA-II): a randomised, single-blind trial. Lancet." 2014 Oct 18. 1446-1454.
Chan MTV, Gin T. "Perioperative outcome after nitrous oxide anaesthesia: an ENIGMA trial. Hong Kong Med J. 2014 Jun. 34-35.
Short TG, Leslie K, Campbell D, Chan MTV, Corcoran T, O'Loughlin E, Frampton C, Myles P. "A pilot study for a prospective, randomized, double-blind trial of the influence of anesthetic depth on long-term outcome." Anesth Analg. 2014 May. 981-986.
Devereaux PJ, Mrkobrada M, Sessler DI, Leslie K, Alonso-Coello P, Kurz A, Villar JC, Sigamani A, Biccard BM, Meyhoff CS, Parlow JL, Guyatt G, Robinson A, Garg AX, Rodseth RN, Botto F, Lurati Buse G, Xavier D, Chan MTV, Tiboni M, Cook D, Kumar PA, Forget P, Malaga G, Fleischmann E, Amir M, Eikelboom J, Mizera R, Torres D, Wang CY, VanHelder T, Paniagua P, Berwanger O, Srinathan S, Graham M, Pasin L, Le Manach Y, Gao P, Pogue J, Whitlock R, Lamy A, Kearon C, Baigent C, Chow C, Pettit S, Chrolavicius S, Yusuf S; POISE-2 Investigators. "Aspirin in patients undergoing noncardiac surgery." N Engl J Med. 2014 Apr 17. 1494-1503.





2013

Wong KC, Chan MTV, Poon WS.? "Preconditioning Strategy: Coronary Bypass, Subarachnoid Hemorrhage, Temporary Proximal Vessel Occlusion in Carotid Revascularization, and Intracranial Aneurysm Surgery".? 2013. 567-568 pgs.
Ho SS, Chan MTV. ?"Anesthesia for Patients with Hilar Cholangiocarcinoma". ?Hilar Cholangiocarcinoma.? Ed by Lau WY. USA.? People's Medical Publishing House. 2013.


Chan MTV, Cheng BCP, Lee TMC, Gin T. ?"BIS-Guided Anesthesia Decreases Postoperative Delirium and Cognitive Decline". J Neurosurg Aneshtesiol 2013;25;33-42.

Fong AWY, Lam KC, Cheng BCP, Lam KK, Chan MTV.? "A Randomised Comparison of InnoScope and Macintosh Laryngoscope in Simulated Difficult Tracheal Intubation in Manikins".? Anaesthesia 2013;68;167-174.

Chan MTV, Chow BKM, Chu CY, Hui SCD.? "Mask Ventilation and Dispersion of Exhaled Air". Am J Resp Med Crit Care 2013;187;e12-e14.

Fong AWY, Lam KC, Cheng BCP, Lam KK, Chan MTV.? "A Reply". Anaesthesia 2013;68;545.


Chen Y, Liu XD, Cheng CHK, Gin T, Leslie K, Myles Paul, Chan MTV.? "Leukocyte DNA Damage and Wound Infection After Nitrous Oxide Administration A Randomized Controlled Trial".? Anesthesiology 2013;118;1258-1260.
Liu X, Tian Y, Lu N,Gin T, Cheng CH, Chan MTV.? “Stat3 Inhibition Attenuates Mechanical Allodynia Through Transcriptional Regulation of Chemokine Expression in Spinal Astrocytes”.? Public Library of Science One 2013;8;10;e75804.






2012

Chan MTV, Kan KY.? Blood Loss During Spine Surger. Essentials of Neurosurgical Anesthesia and Critical Care: Strategies for Prevention, Early Detection and Successful Management of Perioperative Complications. By Brambrink A, Kirsch JR. Springer, 2012; 289-298.
Woo PY, Wong KC, Chan MTV, Poon WS.? Magnesium in Ischemic Stroke and Subarachnoid Hemorrhage.? Metal Ion in Stroke. Springer Link, 2012;481-521.
Wong KC, Chan MTV, Poon WS.? Preconditioning Strategy: Coronary Bypass, Subarachnoid Hemorrhage, Temporary Proximal Vessel Occlusion in Carotid Revascularization and Intracranial Aneurysm Surgery.? Innate Tolerance in the CNS. Springer New York. 2012;567-577.
Chan MTV, Wang Q, Liu H, Liu Q. Growth Hormone and Insulin-Like Growth Factor-1 for Spinal Cord Injury: A Porcine Study.? Anesthesiology 2012;A1202.
Chan MTV, Ho SS, Gin T.? Performance of The Bispectral Index during Electrocautery.? J Neurosurg Anesthesiol 2012;24:9-13
Wong KC, Boet R, Ng CP, Chan MTV, Gin T, Zee BCY, Poon WS.? Ultra-Early (Within 24 Hours) Aneurysm Treatment After Subarachnoid Hemorrhage.? World Neurosurgery 2012;77:311-315.
Wong J,? Lam DPL, Abrishami A, Chan MTV,? Chung F.? Short-Term Preoperative Smoking Cessation and Postoperative Complications: A Systematic Review and Meta-Analysis. Can J Anesth 2012;59:268-279..
Devereaux PJ, Chan MTV, Eisenach JE, Schricker T, Sessler DI.? The Need for Large Clinical Studies in Perioperative Medicine.? Anesthesiology 2012;116:1169-75
Devereaux PJ; Chan MTV, Alonso-Coello P, Walsh M, Berwanger O, Villar JC, Wang CY, GaruttiI RI, Jacka MJ, Sigamani A, Srinathan S, Biccard BM, Chow CK, Abraham V, TIiboni M, Pettit S, Szczeklik W, Luratibuse G, Botto F, Guyatt G, Heels-AnsdellL D, Sessler DI, Thorlund K, Garg AX, Mrkobrada M, Thomas S, Rodseth RN, Pearse RM, Thabane L, Mequeen MJ, Vandhelder T, Bhandari M, Bosch J, Kurz A, Polanczyk C, Malaga G, Nagele P, Le Manach Y, Leuwer M, Yusuf S, Choi GYS, Gin T.? Association between Postoperative Troponin Levels and 30-Day Mortality among Patients Undergoing Noncardiac Surgery.? JAMAVascular Events In Noncardiac Surgery Patients Cohort Evaluation (VISION) Study Investigators 2012;307:2295-2304.
Sheth T, Butler C, Chow B, Chan MTV, Mitha A, Nagele P, Tandon V, Stewart L, Graham M, Choi GYS, Kisten T, Woodward PK, Crean A, Abdul Aziz YF, Karthikeyan G, Chow CK, Szczeklik W, Markobrada M, Mastracci T, Devereaux PJ.? The Coronary CT Angiography Vision Protocol: A Prospective Observational Imaging Cohort Study in Patients Undergoing Non-Cardiac Surgery.? BMJ Open for the CTA VISION Investigators 2012;2:e001474.
Chan MTV, Wang Q, Liu Q, Liu H, Ni W.? Optimal Stimulation Protocols for Transcranial Electrical Motor Evoked Potentials: A Porcine Study.? Anesthesiology 2012;A1187
Devereaux PJ, Chan MTV, Alonso-Coello P.? Troponin Levels and Mortality After Noncardiac Surgery Reply.? JAMAon behalf of the Vascular Events in Noncardiac Surgery Patients Cohort Evaluation (VISION) Study Investigators 2012;308:1205
Konstantatos A, Imberger G, Angliss M, Cheng CHK, Meng Z, Chan MTV.? A Prospective Cohort Study Comparing Early Opioid Requirement Between Chinese from Hong Kong and Caucasian Australians after Major Abdominal Surgery.? British Journal of Anaesthesia2012;109:797-803.
Hui DSC, Chow BKM, Chu CY, Ng Susanna, Lee NLS, Gin T, Chan MTV.? Exhaled Air Dispersion During Coughing With and Without Wearing a Surgical or N95 Mask.? Public Library of Science one 2012;7(12):e50845.




2011

Ho SS, Chan MTV .? Anesthesia for Patients with Hilar Cholangiocarcinoma.? Hilar Cholangiocarcinoma 2011.
Chan MTV, Kan KY.? Blood Loss During Spine Surgery.? Essentials of Neurosurgical Anesthesia and Critical Care: Strategies for Prevention, Early Detection, and Successful Management of Perioperative Complications 2011.
Wong KC, Boet R, Poon WS, Chan MTV, Gin T, Ng CP, Zee CYB.? Intravenous Magnesium Sulphate for Aneurysmal Subarachnoid Hemorrhage: An Updated System Review and Meta-Analysis.? Crit Care 2011;15:R52. Epub 2011 Feb 7.
Hui DS, Chow BK, Chu L, Ng SS, Lai ST, Gin T, Chan MT. Exhaled Air Dispersion and Removal Is Influenced by Isolation Room Size and Ventilation Settings during Oxygen Delivery via Nasal Cannula. Respirology. 2011 Aug;16(6):1005-13. Epub May 23.
Wong KC, Poon WS, Chan MTV, Boet R, Gin T, Ng CP, Zee CYB.? Health-Related Quality of Life after Aneurysmal Subarachnoid Haemorrhage: Profile and Clinical Factors.? Neurosurgery 2011 Jun;68(6):1556-61. Epub Feb 9.
Wong KC, Chan MTV, Gin T, Poon WS.? Intravenous Magnesium Sulfate After Aneurysmal Subarachnoid Hemorrhage: Current Status.? Acta Neurochir Suppl 2011;110(Pt2):169-173.
Leslie K, Myles PS, Chan MTV, Forbes A, Paech MJ, Peyton P, Silbert BS, Williamson E.? Nitrous Oxide and Long-Term Morbidity and Mortality in the ENIGMA Trial.? Anesth Analg 2011;112:387-393.
Chan MTV, Wan CM, Gin T, Leslie K, Myles PS.? Chronic Postsurgical Pain after Nitrous Oxide Anesthesia.? PAIN? 2011;152:2514-2520.




2010

Leslie K, Chan MT, Myles PS, Forbes A, McCulloch TJ.? Posttraumatic Stress Disorder in Aware Patients from the B-Aware Trial.? Anesth Analg 2010;110:823-828.


Leslie K, Myles PS, Forbes A, Chan MT.? The Effect of Bispectral Index Monitoring on Long-Term Survival in the B-Aware Trial.? Anesth Analg 2010;110:816-822.

Wong GK, Poon WS, Chan MT, Boet R, Gin T, Ng SC, Zee BC.? Plasma Magnesium Concentrations and Clinical Outcomes in Aneurysmal Subarachnoid Hemorrhage Patients.? Post Hoc Analysis of Intravenous Magnesium Sulphate for Aneurysmal Subarachnoid Hemorrhage Trial.? Stroke 2010.

Chan MTV.? Intravenous Magnesium Sulfate for Aneurysmal Subarachnoid Hemorrhage (IMASH) Trail.? J Neurosug Anesthesiol 2010;22:411-412.

Arango MF, Craen R A, Chan MTV.? Randomized Comparison of 20% Mannitol and 7.5% Hypertonic Saline for Supratentorial Craniotomy.? Anesthesiology 2010;A784-.

Chan MTV.? Intravenous Magnesium Sulfate for Aneurysmal Subarachnoid Hemorrhage (IMASH) Trail.? Anesthesiology 2010;A1131.

Chan MTV, Cheng BCP, Gin Tony, Lam Kwok Key, Koo Emily Gar Yee.? Cognitive Dysfunction After Anesthesia (CoDA): A Ramdomized Controlled Trial.? Anesthesiology 2010;A139.

Devereaux PJ, Chan MTV, Ekielboom J.? Major Vascular Complications in Patients Undergoing Non-Cardiac Surgery: Magnitude of the Problem, Risk Prediction, Surveillance, and Prevention (Chapter 5).? Evidence Based Cardiolgoy ;47-62.

Wong KC, Poon WS, Chan MTV, Boet R, Gin T, Ng CP, Zee CYB.? Magnesium Sulfate for Subarachnoid Hemorrhage: A Piece of the Mosaic Response.? Stroke 2010;41:e577.

Wong KC, Yeung DTW, Ahuja AT, King A, Lam WKC, Chan MTV, Gin T, Poon WS.? Intracellular Free Magnesium of Brain and Cerebral Phosphorus-Containing Metabolites After Subarachnoid Hemorhage and Hypermagnesemic Treatment: A 31P-Magnetic Resonance Spectroscopy Study.? J Neurosurg 2010;113:763-769.

Chan MTV, Chen Y, Liu XD, Cheng CHK, Gin T, Leslie K, Myles PS.? Genomic Stability after Nitrous Oxide Administration.? Anesthesiology 2010;A1334.





2009


Hui DSC, Hall S, Chan MTV, Joynt GM, Chow B, Sung JJY.? Risks Posed by the Use of Oxygen Therapy and Non-invasive Positive Pressure Ventilation: A Pilot Study.? Hong Kong Med J 2009;15:4-7.

Hui SCD, Chow BK, Ng S, Chu LC, HALL SD, Gin T, Sung JJY, Chan MTV.? Exhaled Air Dispersion Distances During Nonninvasive Ventilation Via Different Respironics Face Masks.? Chest 2009;135:998-1005.

Wong GK, Lam CW, Chan MTV, Gin T, Poon WS.? The Effect of Hypermagnesemic Treatment on Cerebrospinal Fluid Magnesium Level in Patients With Aneurysmal Subarachnoid Hemorrhage.? Magnesium Research 2009;22:60-65.

Hui SCD, Chow BKM, Chu CY, Ng S, Hall DS, Gin T, Chan MTV.? Exhaled Air and Aerosolized Droplet Dispersion During Application of a Jet Nebulizer.? Chest 2009;135:648-654.

Wong GK, Yeung DK, Ahuja AT, King AD, Lam CW, Chan MT, Gin T, Poon WS.? Intracellular Free Magnesium of Brain and Cerebral Phosphorus-Containing Metabolites After Su7barachnoid Hemorhage and Hypermagnesemic Treatment: A (31) P-magnetic Resonance Spectroscopy Study.? J Neurosurg?? 2009.

Chan MTV, Wong KC, Ahuja AT, King A, Gin T, Poon WS.? Intravenouse Magnesium Sulfate Infusion Elevates Neuronal Free Magnesium Concentration.? J Neurosurg Anesthesiol 2009;21:367.

Chan MTV, Wong KC, Ahuja AT, Lam CWK, ?King A, Gin T, Poon WS.? Intravenous Magnesium Sulfate Infusion Elevates Neuronal Free Magnesium Concentration.? Anaesethesiology 2009;A516.

Jensen EW, Chan MTV, Gumbus P.? Prediction of the Index of Consciousness (IoC) by Fuzzy Logic of the Auditory Evoked Potential.? Anesthesiology? 2009;A380.

Kwan A, Chan MTV, Lui J, Lau L, Das DR, Chow YF, Law B, Hui T, Ho B.? Per-Operative Mortality Case Reports.? Quality Assurance Subcommittee, Coordinating Committee (Anaesthesiology) 2009.

Karthikeyan G, Moncur RA, Levine O, Heels-Ansdell D, Chan MTV, Alonso-Coello P, Yusuf S, Sessler D, Villar JC, Berwanger O, Mcqueen M, Mathew A, Hill S, Gibson S, Berry C, Lai LP Devereaux PJ.? Is a Preoperative BNP or NT-pro BNP Measurement An Independent Predictor of Adverse Cardiovascular Outcomes Within 30 days of Noncardiac Surgery? A Systemic Review and Meta-Analysis of Observational Studies.? J Am coll Cardiol 2009;54:1599-1606.

Wong KC, Yeung DK, Ahuja AT, King A, Chan MTV, Lam CWK, Poon WS.? The Effect of Energy Metabolism and Intracellular Free Magnesium of Brain After Good Grade Subarachnoid Haemorrhage.? J Cereb Blood Flow Metab 2009;29:S300.



2008

Chan MTV, Lo CCK, Lok CKW, Chan TW, Choi KC, Gin T.? Psychometric Testing of the Chinese Quality of Recovery Score. Anesth Analg 2008;107:1189-95.
Devereaux PJ, Yang H, Yusuf S, Guyatt G, Leslie K, Villar JC, Xavier D, Chrolavicius S, Greenspan L, Pogue J. Pais P, Liu LS, Xu S, Malaga G, Avezum A, Chan MTV, Montori VM, Jacka M, Choi P.? Effects of Extended-Release Metoprolol Succinate in Patients Undergoing Noncardiac Surgery (POISE trial): A Randomised Controlled Trial.? Lancet 2008;371:1839-47.

Gelb WA, Craen AR, Rao U, Reddy KM, Megyesi J, Mohanty B, Dash HH, Choi KC, Chan MTV.? Does Hyperventilation Improve Operating Condition During Supratentorial Craniotomy? A Multicenter Randomized Crossover Trial. Anesth Analg 2008;106:585-94.
Myles PS, Chan MTV, Leslie K, Peyton P, Paech M, Forbes A.? Effect of Nitrous Oxide on Plasma Homocysteine and Folate in Patients Undergoing Major Surgery.? Br J Anaesth 2008;100:780-86.
Wong KC, Ng CP, Chan MTV, Sun TFD, Lam WM, Lam JMK, Poon WS.Impaired Transcranial Doppler Ultrasound Cerebrovascular Reactivity before Carotid Intervention is not Predictive of a Subsequent Ischaemic Event.Surg Pract2008;12:11-5.
Wong KC, Poon WS, Chan MTV.Hypomagnesemia after Ruptured Middle Cerebral Artery Aneurysms: Predictive Factor and Pathophysiological Implication.Acta Neurochir Suppl2008;104:267-8.




2007

Chan MTV, Choi KC, Wong GKC, Poon WS.? Interaction Between Magnesium Sulfate and Acetylsalicylic Acid in the MASH Trial.? Stroke 2007;38:e14.
Chan MTV, Fu YT, Koo EGY, Choi YSG, Gin T.? Combination Antiemetics: Combining Effects or Side Effects?? ASEAN J Anaesthesiol 2007;8:6-13.
Hui DSC, Hall SD, Chan MTV, Chow BKM, Ng SS, Gin T, Sung JJY.? Exhaled Air Dispersion During Oxygen Delivery Via a Simple Oxygen Mask.? Chest 2007;132:540-6.
Ip M, Tang JW, Hui DS, Wong ALN, Chan MTV, Joynt GM, So ATP, Hall SD, Chan PKS, Sung JJY.? Airflow and Droplet Spreading Around Oxygen Masks: A Simulation Model for Infection Control Research.? Am J Infect Control 2007;35:684-9.
Myles PS, Leslie K, Chan MTV, Forbes A, Paech MJ, Peyton P, Silbert BS, Pascoe E.? ENIGMA Trial Group.? Avoidance of Nitrous Oxide for Patients Undergoing Major Surgery: A Randomised Controlled Trial.? Anesthesiology 2007;107:221-31.
Wong KC, Poon WS, Chan MTV, Gin T, Boet R.? The Effect of Intravenous Magnesium Sulfate Infusion on Serum Levels of Sodium and Potassium in Patients With Aneurysmal Subarachnoid Hemorrhage.? Magnes Res 2007;20:37-42.




2006

Chan MTV, Gin T.? Changes of Bispectral Index After a Bolus Dose of Muscle Relaxant.? Anesth Analg 2006;103:776-7.
Chan MTV, Gin T.? QTc Changes After Ondnasetron and Droperidol for the Prevention of Postoperative Nausea and Vomiting.? Anesthesiology 2006;A1386.
Chan MTV, Ng SCP, Poon WS, Gin T.? The Lower Limit of Cerebral Perfusion Pressure in Head Injured Patients.? Anaesthesiology 2006;A571.
Gin T, Chan MTV, Wong G, Boet R, Poon W.? Intravenous Magnesium Sulfate to Improve Outcome after Aneurysmal Subarachnoid Hemorrhage.? Anaesth Intensive Care 2006;34:542.
Gin T, Tang YK, Chan MTV, Chui PT.? Tracheal Tube Advancement During Fibreoptic Intubation: A Randomized Comparison of Three Techniques.? Anaesthesiology 2006;A869.
Hui DS, Hall SD, Chan MTV, Chow BK, Tsou JY, Joynt GM, Sullivan CE, Sung JJY.? Non-invasive Positive-Pressure Ventilation: An Experimental Model to Assess Air and Particle Dispersion.? Chest 2006;130:730-40.
Hui DS, Ip M, Tang JW, Wong ALN, Chan MTV, Hall SD, Chan PKS, Sung JJY.? Airflows Around Oxygen Masks: A Potential Source of Infection?? Chest 2006;130:822-6.
Myles PS, Chan MTV, Forbes A, Leslie K, Paech MJ, Peyton P.? Preoperative Folate and Homocysteine Status in Patients Undergoing Major Surgery.? Clin Nutr?2006;25:736-45.
Ng SC, Poon WS, Chan MTV.? Cerebral Hemisphere Asymmetry in Cerebrovascular Regulation in Ventilated Traumatic Brain Injury.? Acta Neurochir Suppl 2006;96:21-3.
Siu NSN, Chan MTV, Lau TK.? Placental Transfer of Ondansetron During Early Human Pregnancy (In press).? Clin Pharmacokinet 2006;45:419-23.
Wong GK, Chan MTV, Boet R, Poon WS.? Dose Evaluation for Long-Term Magnesium Treatment in Aneurysmal Subarachnoid Haemorrhage.? J Clin Pharm Ther 2006;31:407.
Wong GKC, Chan MTV, Poon WS, Boet R, Gin T.? Magnesium Therapy within 48 Hours of an Aneurysmal Subarachnoid Hemorrhage: Neuro-Panacea. Neurol Res 2006;28:1-5.
Wong GKC, Chan MTV, Boet R, Poon WS, Gin T.? Intravenous Magnesium Sulfate After Aneurysmal Subarachnoid Hemorrhage: A Prospective Randomized Pilot Study.? J Neurosurg Anesthesiol 2006;18:142-8.




2005

Boet R, Chan MTV, Poon WS, Wong GK, Wong HT, Gin T. Intravenous Magnesium Sulphate to Improve Outcome After Aneurysmal Subarachnoid Hemorrhage: Interim Report from a Pilot Study.Acta Neurochir Suppl2005;95:263-4.
Chan MTV, Boet R, Ng SCP, Poon WS, Gin T.? Effect of Ischemic Preconditioning on Brain Tissue Gases and pH During Temporary Cerebral Artery Occlusion.? Acta Neurochir Suppl 2005;95:93-6.
Chan MTV, Boet R, Ng SCP, Poon WS, Gin T.? Magnesium Sulfate for Brain Protection During Temporary Cerebral Artery Occlusion.? Acta Neurochir Suppl 2005;95:107-11.
Chan MTV, Ng SCP, Lam JMK, Poon WS.? Re-Defining the Ischemic Threshold for Jugular Venous Oxygen Saturation - A Microdialysis Study in Patients With Severe Head Injury.? Acta Neurochir Suppl 2005;95:63-6.
Chan MTV, Ng SCP, Lam JMK, Poon WS, Gin T.? Monitoring of Autoregulation Using Intracerebral Microdialysis in Patients With Severe Head Injury.? Acta Neurochir Suppl 2005;95:113-6.
Leslie K, Myles PS, Forbes A, Chan MTV, Short TG, Swallow SK.? Recovery from Bispectral Index-Guided Anaesthesia in a Large Randomised Controlled Trial of Patients at High Risk of Awareness.? Anaesth Intensive Care 2005;33:443-51.
Leslie K, Myles PS, Forbes A, Chan MTV, Swallow SK, Short TG.? Dreaming During Anaesthesia in Patients at High Risk of Awareness.? Anaesthesia 2005;60:239-44.
Ng SC, Poon WS, Chan MTV. Cerebral haemodynamic assessment in patients with thalamic haemorrhage: a pilot study with continuous compliance monitoring. Acta Neurochir Suppl 2005;95:299-301.

Poon WS, Lam JMK, Chan MTV, Goh KYC, Marmarou A, Teasdale GM. Intracranial Pressure and Brain Monitoring.In: Poon WS, Lam JM, Chan MTV, Goh KYC, Marmarou A, Teasdale GM, eds.Springer-Verlag/Wein,2005.
Poon WS, Ng SC, Chan MTV, Lam JMK, Lam WWM.Cerebral Blood Flow (CBF)-Directed Management of Ventilated Head-Injured Patients.Acta Neurochir Suppl 2005;9-11.



2004

Chan MTV, Gin T, Goh KYC.? Interventional Neurophysiologic Monitoring.? Curr Opin Anaesthesiol 2004;17:389-96.
Chan MTV, Ho SS, Gin T.? AEP 'Click Detection" Failure: May Be, May Be Not! Anesth Analg 2004;99:948-9.
Chan MTV, Ng S, Sun DTF, Lam JMK, Poon WS, Gin T.? Carbon Dioxide Vasomotor Reactivity of the Infraclinoid Internal Carotid Artery.? J Neurosurg Anesthesiol 2004;16:332-3
Kwok RFK, Lim J, Chan MTV, Gin T, Chiu WKY.? Preoperative Ketamine Improves Postoperative Analgesia After Gynecologic Laparoscopic Surgery.? Anesth Analg 2004;98:1044-9.
Myles PS, Leslie K, Forbes A, McNeil J, Chan MTV.? B-Aware: Recall of Intraoperative Events.? Lancet 2004;364:841-2.
Myles PS, Leslie K, McNeil J, Forbes A, Chan MTV.? Bispectral Index Monitoring to Prevent Awareness During Anaesthesia: The B-Aware Randomised Controlled Trial.? Lancet 2004;363:1757-63.
So CY, Gomersall CD, Chui PT, Chan MTV.? Performance of An Oxygen Delivery Device for Weaning Potentially Infectious Critically Ill Patients.? Anaesthesia 2004;59:710-4.




2003

Boet R, Poon WS, Chan MTV.Magnesium Sulphate in Aneurysmal Subarachnoid Haemorrhage - the Need for a Large Multi-center Study (Letters to the Editor).J Clin Neurosci2003;10:394.

Chan KL, Chan MTV, Gin T.? Mainstream vs. Sidestream Capnometry for Prediction of Arterial Carbon Dioxide Tension During Supine Craniotomy.? Anaesthesia 2003;58:149-55.
Chan MTV, Boet R, Ng S, Poon WS, Gin T.? Magnesium Sulfate for Brain Protection During Temporary Cerebral Artery Occlusion.? J Neurosurg Anesthesiol 2003;15:373.
Chan MTV, Boet R, Poon WS, Gin T.? Magnesium Sulfate for Brain Protection During Temporary Cerebral Artery Occlusion.? Anesthesiology 2003;99:A351.
Chan MTV, Gin T, Chui AK, Lau WY.? Pitfalls of Indocyanine Green Dye Elimination to Assess Graft Function During Liver Transplantation.? Anesth Analg 2003;96:1839-40.
Myles PS, Leslie K, Forbes A, Chan MTV, McNeil.? A Large Randomized Trial of BISTM Monitoring to Prevent Awareness in High Risk Patients: The B-Ware Trail.? Anesthesiology 2003;99:A320.
Ng S, Poon WS,Chan MTV.The Role of Haematoma Aspiration in the Management of Patients with Thalamic Haemorrhage: A Pilot Study with Continuous Compliance Monitoring.Acta Neurochir Suppl 2003;86:469-71.




2002

Chan MTV, Gin T, Boet R, Poon W.? Intravenous Magnesium Sulfate to Improve Outcome after Aneurysmal Subarachnoid Hemorrhage.? J Neurosurg Anesthesiol 2002;14:342.
Chan MTV, Gin T, Boet R, Poon WS.? Intravenous Magnesium Sulfate to Improve Outcome after Aneurysmal Subarachnoid Hemorrhage.? Anesthesiology 2002;97:A529.
Gelb AW, Graen RA, Chan MTV, Rao U.? Hyperventilation Does Not Improve Neurosurgical Operating Conditions During Supratentorial Craniotomy.? J Neurosurg Anesthesiol 2002;15:376.
Gin T, Chan MTV, Chan KL.Quality of Recovery After Auditory Evoked Potential Guided Anesthesia. Anesth Analg2002;94:S157.
Gin T, Chan MTV, Chan KL, Yuen PM.? Prolonged Neuromuscular Block After Rocuronium In Postpartum Patients.? Anaesth Analg 2002;94:686-9.
Ho AMH, Chan MTV.? Awareness During Anesthesia.? Eur J Anaesthesiol 2002;19:618-9.
Lok IH, Chan MTV, Tam WH, Leung PL, Yuen PM.? Patient-Controlled Sedation for Outpatient Thermal Balloon Endometrial Ablation.? J Am Assoc Gynecol laparosc 2002;9:436-41.
Lok IH, Chan MTV, Chan DLW, Cheung LP, Haines CJ, Yuen PM.? A Prospective Randomized Trail Comparing Patient-Controlled Sedation Using Propofol and Alfentanil and Physician-Administered Sedation Using Diazepam and Pethidine During Transvaginal Ultrasound-Guided Oocyte Retrieval.? Hum Reprod 2002;17:2101-6.
Ng SCP, Poon WS, Chan MTV, Lam JMK, Lam WWM.? Is Transcranial Doppler Ultrasonography (TCD) Good Enough in Determining CO2 Reactivity and Pressure Autoregulation in Head-Injured Patients?? Acta Neurochir Suppl 2002;81:125-7.
Poon WS, Ng SC, Chan MTV, Leung CH, Lam JM.? Neurochemical Changes in Ventilated Head-Injured Patients with Cerebral Perfusion Pressure Treatment Failure.? Acta Neurochir Suppl 2002;81:335-8.
To EWH, Tsang WM, Williams MD, Lai ECH, Chan MTV.? Tracheal Necrosis and Surgical Emphysema: A Rare Complication of Thyroidectomy.? Ear Nose Throat J 2002;81:738-41.
Tong MCF, Lam JMK, Wong TKC, Chan MTV, Poon WS, Van hasselt CA.? Neurofibromatosis II and the 24-Channel Auditory Brainstem Implant.? Cochlear Implants - An Update 2002;549-52.




2001

Chan MTV, Ng S, Sun D, Lam JMK, Poon WS, Gin T.? Carbon Dioxide Vasomotor Reactivity of the Infraclinoid Internal Carotid Artery - Cerebral Vasomotor Reactivity I Carotid Artery Disease. A Comparison of Infraclinoid Internal Cartoid Artery to Distal Middle Cerebral Artery.? J Cereb Blood Flow Metab 2001;21:S206.
Chan MTV, Ng SK, Chui PT, Tan PE, Gin T.Hemodynamic Changes and Catecholamine Release During Laparoscopic Adrenalectomy for Primary Hyperaldosteronism. Anesthesiology2001;95:A218.
Lam KK, Chan MTV, Chen PP, Ngan Kee WD.? Structured Preoperative Patient Education for Patient-Controlled Analgesia.? J Clin Anesth 2001;13:465-9.
Lok CK, Chan MTV, Martinson IM.? Risk Factors for Citation Errors in Peer-Reviewed Nursing Journals.? J Adv Nurs 2001;34:223-9.
Ng SCP, Poon WS, Chan MTV, Lam WWM.? Side-to-side Difference in Pressure Autoregulatory Response in Ventilated Head-Injured Patients.? J Cereb Blood Flow Metab 2001;21:S183.




2000

Chan MTV, Chui PT, Tam YH, Gin T.? Prospective Validation of the Context Sensitive Half Times for Propofol.? Anesthesiology 2000;93:A518.
Chan MTV, Gin T.? What Does the Bispectral EEG Index Monitor?.? Eur J Anaesthesiol 2000;17:146-8.
Chan MTV, Ng S, Leung C, Lam J, Poon WS, Gin T.? Re-Defining the Ischemic Threshold for Jugular Venous Oxygen Saturation - A Microdialysis Study in Patients With Severe Head Injury.? J Neurosurg Anesthesiol 2000;12:386.
Chee YE, Chan MTV, Aun CST, Gin T.? Age Dependent Changes in the Dose-Response Relation of Ci-satracurium During Propofol Anesthesia.? Anesthesiology 2000;93:A1007.
Gin T, Chan MTV, Chan A, Yuen PM.? Duration of Rocuronium Block in Postpartum Patients.? Anaesth Intensive Care 2000;28:215-6.
Gin T, Chan MTV, Chui PT, Suen TKL.? Double-Blind, Randomized Comparison of Ondansetron-Thiopental With Propofol to Prevent PONV.? Eur J Anaesthesiol 2000;17:A-389.
Ng SCP, Poon WS, Chan MTV, Lam JMK, Lam WWM, Metreweli C.Transcranial Doppler Ultrasonography (TCD) in Ventilated Head Injured Patients: Correlation with Stable Xenon-Enhanced CT. Acta Neurochir (Suppl)2000;76:479-82.




1998-1999

Chan KL, Chan MTV, Gin T.? Main Stream Sampling of End-Tidal CO2, Improves Prediction of Arterial CO2 Tension During Neurosurgical Procedures.? J Neurosurg Anesthesiol 1998;10:290.

Chan MTV, Chui PT, Ho WS, King WWK.? Single-Dose Tropisetron for Preventing Postoperative Nausea and Vomiting After Breast Surgery. ?Anesth Analg 1998;87:931-5.

Chan MTV, Gin T.? The Anti-Emetic Efficacy of a Combination of Ondansetron and Droperidol. ?Anaesthesia 1998;53:413.

Chan MTV, Gin T, Lau TK, Lam KK.? Increased Hypnotic Effect on N2O During Pregnancy .? Anaesth Intensive Care 1998;26:695-6.

Chan MTV, Gin T, Poon WS.? Propofol Requirements is Decreased in Patients with Supratentorial Brain Tumor.? J Neurosurg Anesthesiol 1998;10:278.

Chan MTV, Gin T, Suen T, Chui PT, Short T.? PONV After Ketorolac VS Fentanyl in Patients Undergoing Minor Gynecologic Laparoscopy.? In: Mori K, Ohmura A, Toyooka H, Hatano Y, Shingu K, Fukuda K, eds.? New Balanced Anesthesia.? Amsterdam: Elsevier, 1998;331-3.
Gin T, Chan MTV, Lau TK, Lam KK.? Pregnancy Potentiates the Sedative Effects of Nitrous Oxide.? Anesthesiology 1998;89:A1042.

Gin T, Derrick JL, Chan MTV, Chui PT, Mak TW.? Postpartum Patients Have Slightly Prolonged Neuromuscular Block After Mivacurium.? Anaesth Anagl 1998;86:82-5.

Lam JMK, Chan MTV, Poon WS, Oh TE.? Multimodality Monitoring During Carotid Endaterectomy - A Technical Note.? Ann Coll Surg1998;1:72-4.
Wong WCW, Chan MTV, Lau TK, Fung TY, Mainland PA, Chung DC.? Oxytocic Effect of Syntocinon During Early Pregnancy.? Anesthesiology 1998;89:A1051.
Chan F, Chan MTV, Sun D, Boet R, Lam J, Ng S.? Defining Abnormal Acetazolamide Reactivity Test in Patients with Carotid Artery Stenosis - A Comparison with CO2 Reactivity.? J Neurosurg Anesthesiol 1999;11:334.
Chan MTV, Gin T, Poon WS.? Propofol Requirement is Decreased in Patients with Large Supratentorial Brain Tumor.? Anesthesiology 1999;90:1571-6.

Chan MTV, Lam JMK.? New Monitors of Neurological Functions - Part 1.? Curr Anaesth Crit Care 1999;10:87-97.

Chan MTV, Lam JMK.? New Monitors of Neurological Functions - Part 2.? Curr Anaesth Crit Care 1999;10:147-57.

Chan MTV, Ng S, Lam J, Poon W, Lam W.? Correlation of TCD Flow Velocity with Regional CBF in Patients with Supratentorial Mass Lesion.? Anesthsiology 1999;91:A494.

Chan MTV, Ng S, Lam J, Poon WS, Gin T, Lam W.? Measurement of Regional Cerebral Blood Flow Using Near Infrared Spectroscopy - the Influence of Extracranial Contamination.? J Neurosurg Anesthesiol 1999;11:307.