Low-grade myofibroblastic sarcoma: A population-based study
Publication in refereed journal


香港中文大学研究人员 ( 现职)

Professor VLANTIS Alexander Chris (耳鼻咽喉-头颈外科学系)

唐志辉教授 (耳鼻咽喉-头颈外科学系)

陈英权教授 (耳鼻咽喉-头颈外科学系)

全文

数位物件识别号 (DOI) http://dx.doi.org/10.1002/lary.26146

引用次数
Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/1WOS source URL
Scopushttp://aims.cuhk.edu.hk/converis/portal/Publication/1Scopus source URL

其它资讯

摘要Objectives/Hypothesis: Low-grade myofibroblastic sarcoma (LGMS) is a rare entity that is described as having a predilection for occurring in the head and neck region. Here we analyze its demographics, clinic-pathologic, and survival characteristics. Study Design: Retrospective database analysis. Methods: A cohort from the Surveillance, Epidemiology, and End Results Program database of cases with LGMS between 200http://aims.cuhk.edu.hk/converis/portal/Publication/1 and 20http://aims.cuhk.edu.hk/converis/portal/Publication/12. Results: There were 49 cases with a 5-year overall survival of 7http://aims.cuhk.edu.hk/converis/portal/Publication/1.6% and disease- specific survival of 76.3%. The majority of cases were in patients <60 years old, female, and white ethnicity. The most common sites were the extremities in 40.8% of cases followed by the head and neck region with 26.5% of cases. Multivariate analysis showed that only older age was significantly associated with worse survival (P <.05). Conclusions: LGMS is uncommon in the United States and occurs most commonly in the extremities followed by the head and neck region, despite an existing characterization of a predilection for the head and neck region. Treatment most commonly involves surgery, but the optimal surgical extent and/or radiotherapy needs to be further investigated. Level of Evidence: 2c Laryngoscope, http://aims.cuhk.edu.hk/converis/portal/Publication/127:http://aims.cuhk.edu.hk/converis/portal/Publication/1http://aims.cuhk.edu.hk/converis/portal/Publication/16–http://aims.cuhk.edu.hk/converis/portal/Publication/12http://aims.cuhk.edu.hk/converis/portal/Publication/1, 20http://aims.cuhk.edu.hk/converis/portal/Publication/17.

着者Chan J.Y.K., Gooi Z., Wong E.W.Y., Ng S.K., Tong M.C.F., Vlantis A.C.
期刊名称LARYNGOSCOPE
详细描述doi: http://aims.cuhk.edu.hk/converis/portal/Publication/10.http://aims.cuhk.edu.hk/converis/portal/Publication/1002/lary.26http://aims.cuhk.edu.hk/converis/portal/Publication/146.
出版年份20http://aims.cuhk.edu.hk/converis/portal/Publication/17
月份http://aims.cuhk.edu.hk/converis/portal/Publication/1
日期http://aims.cuhk.edu.hk/converis/portal/Publication/1
卷号http://aims.cuhk.edu.hk/converis/portal/Publication/127
期次http://aims.cuhk.edu.hk/converis/portal/Publication/1
出版社Lippincott Williams & Wilkins Ltd.
出版地United States
页次http://aims.cuhk.edu.hk/converis/portal/Publication/1http://aims.cuhk.edu.hk/converis/portal/Publication/16 - http://aims.cuhk.edu.hk/converis/portal/Publication/12http://aims.cuhk.edu.hk/converis/portal/Publication/1
国际标準期刊号0023-852X
电子国际标準期刊号http://aims.cuhk.edu.hk/converis/portal/Publication/153http://aims.cuhk.edu.hk/converis/portal/Publication/1-4995
语言英式英语

关键词Low-grade myofibroblastic sarcoma, myofibroblastic sarcoma