Publication in refereed journal
香港中文大学研究人员 ( 现职)
| 胡嘉麒教授 (麻醉及深切治疗学系) |
| 陈德威教授 (麻醉及深切治疗学系) |
全文
| 数位物件识别号 (DOI) http://dx.doi.org/10.1111/cpr.12342 |
引用次数
Scopushttp://aims.cuhk.edu.hk/converis/portal/Publication/0Scopus source URL
其它资讯
摘要Colon cancer-associated transcript 2 (CCAT2) was originally identified as an oncogenic long non-coding RNA in colorectal cancer. Since its discovery, the oncogenic role of CCAT2 has been increasingly demonstrated in human cancers. In this connection, CCAT2 upregulation is frequently reported and very often associated with tumour progression and poor clinical outcomes. Functionally, knockdown of CCAT2 could induce cancer cell apoptosis and suppress cell proliferation and invasiveness, suggesting that CCAT2 might be a therapeutic target. The present review summarized current literature concerning the expression and functional role of CCAT2 in human malignancies.
着者Yu Xin, Zheng Li, Heyi Zheng, Matthew T.V. Chan,William Ka Kei Wu
期刊名称Cell Proliferation
出版年份2http://aims.cuhk.edu.hk/converis/portal/Publication/017
月份6
卷号5http://aims.cuhk.edu.hk/converis/portal/Publication/0
期次3
出版社Wiley
国际标準期刊号http://aims.cuhk.edu.hk/converis/portal/Publication/096http://aims.cuhk.edu.hk/converis/portal/Publication/0-7722
语言英式英语
