Publication in refereed journal
香港中文大学研究人员 ( 现职)
| 胡嘉麒教授 (麻醉及深切治疗学系) |
| 陈德威教授 (麻醉及深切治疗学系) |
全文
| 数位物件识别号 (DOI) http://dx.doi.org/10.1111/cpr.12329 |
引用次数
Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/0WOS source URL
Scopushttp://aims.cuhk.edu.hk/converis/portal/Publication/0Scopus source URL
其它资讯
摘要Aberrant overexpression of the long non-coding RNA NEAT1 (nuclear paraspeckle assembly transcript 1) has been documented in different types of solid tumours, such as lung cancer, oesophageal cancer, colorectal cancer and hepatocellular carcinoma, in which its high levels are associated with poor prognosis. In contrast, NEAT1 is downregulated in acute promyelocytic leukaemia where it promotes leucocyte differentiation. In this review, we provide an overview of current evidence concerning the oncogenic role and potential clinical utilities of NEAT1. Further investigations are warranted to elucidate the upstream and downstream mechanisms of NEAT1 overexpression.
着者Xin Yu, Zheng Li, Heyi Zheng, Matthew T. V. Chan, William Ka Kei Wu
期刊名称Cell Proliferation
出版年份2http://aims.cuhk.edu.hk/converis/portal/Publication/017
月份4
卷号5http://aims.cuhk.edu.hk/converis/portal/Publication/0
期次2
出版社Wiley
国际标準期刊号http://aims.cuhk.edu.hk/converis/portal/Publication/096http://aims.cuhk.edu.hk/converis/portal/Publication/0-7722
语言英式英语
