Publication in refereed journal
香港中文大学研究人员 ( 现职)
| 李焕坤教授 (麻醉及深切治疗学系) |
| 黎嘉慧 (麻醉及深切治疗学学部) |
| 黄维达教授 (麻醉及深切治疗学系) |
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典藏于此文库的全文
数位物件识别号 (DOI) http://dx.doi.org/10.1002/14651858.CD003587.pub3 |
引用次数
Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/5WOS source URL
其它资讯
摘要Background
Fast-track cardiac care is a complex intervention involving several components of care during cardiac anaesthesia and in the postoperative period, with the ultimate aim of early extubation after surgery, to reduce length of stay in the intensive care unit and in the hospital. Safe and effective fast-track cardiac care may reduce hospital costs. This is an update of a Cochrane review first published in 2003, updated in 2012 and updated now in 2016.
Objectives
To determine the safety and effectiveness of fast-track cardiac care compared with conventional (not fast-track) care in adult patients undergoing cardiac surgery. Fast-track cardiac care intervention includes administration of low-dose opioid-based general anaesthesia or use of a time-directed extubation protocol, or both.
Search methods
We searched the Cochrane Central Register of Controlled Trials (CENTRAL; 201http://aims.cuhk.edu.hk/converis/portal/Publication/5, Issue http://aims.cuhk.edu.hk/converis/portal/Publication/5), MEDLINE (January 2012 to May 201http://aims.cuhk.edu.hk/converis/portal/Publication/5), Embase (January 2012 to May 201http://aims.cuhk.edu.hk/converis/portal/Publication/5), the Cumulative Index to Nursing and Allied Health Literature (CINAHL; January 2012 to May 201http://aims.cuhk.edu.hk/converis/portal/Publication/5) and the Institute for Scientific Information (ISI) Web of Science (January 2012 to May 201http://aims.cuhk.edu.hk/converis/portal/Publication/5), along with reference lists of articles, to identify additional trials. We applied no language restrictions.
Selection criteria
We included all randomized controlled trials of adult cardiac surgical patients (coronary artery bypass grafts, aortic valve replacement, mitral valve replacement) that compared fast-track cardiac care and conventional (not fast-track) care groups. We focused on the following fast-track interventions, which were designed for early extubation after surgery: administration of low-dose opioid-based general anaesthesia during cardiac surgery and use of a time-directed extubation protocol after surgery. The primary outcome was risk of mortality. Secondary outcomes included postoperative complications, reintubation within 24 hours of surgery, time to extubation, length of stay in the intensive care unit and in the hospital, quality of life after surgery and hospital costs.
Data collection and analysis
Two review authors independently assessed trial quality and extracted study data. We contacted study authors for additional information. We calculated a Peto odds ratio (OR) for risk of mortality and used a random-effects model to report risk ratio (RR), mean difference (MD) and 9http://aims.cuhk.edu.hk/converis/portal/Publication/5% confidence intervals (9http://aims.cuhk.edu.hk/converis/portal/Publication/5% CIs) for all secondary outcomes.
着者Wai-Tat Wong, Veronica KW Lai, Yee Eot Chee, Anna Lee
期刊名称Cochrane Database of Systematic Reviews
出版年份2016
期次9
出版社Cochrane Collaboration
国际标準期刊号1469-493X
电子国际标準期刊号1361-6137
语言英式英语
关键词*Coronary Artery Bypass, *Heart Valve Prosthesis Implantation, *Intubation, Intratracheal, Adult, Aortic Aneurysm [*surgery], Aortic Valve [surgery], Controlled Clinical Trials as Topic, Early Ambulation, Humans, Mitral Valve [surgery], Randomized Controlled Trials as Topic, Time Factors
Web of Science 学科类别General & Internal Medicine; Medicine, General & Internal; MEDICINE, GENERAL & INTERNAL
