Refereed conference paper presented and published in conference proceedings
香港中文大学研究人员 ( 现职)
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Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/4WOS source URL
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摘要Much research interest has been shown in recent years for the development of molecular diagnostic strategies based on the analysis of DNA/RNA molecules that are present in the plasma/serum or human Subjects. Reported applications include the diagnosis, prognostication or monitoring of malignancies and pregnancy-associated complications. While researchers have speculated that cell death is a potential mechanism that leads to the release of DNA/RNA into the circulation, studies have demonstrated that indeed increased amounts of plasma DNA and RNA could be detected in patients sustaining acute traumatic injuries. The degree of plasma DNA elevation correlated with the severity of injury. Similarly, plasma DNA concentrations have been shown to correlate with indices of prognostic significance in patients with acute stroke. It is expected that new, diagnostic markers based on plasma RNA detection could be developed for the evaluation of acute pathologies.
着者Chiu RWK, Rainer TH, Lo YMD
会议名称12th International Symposium on Intracranial Pressure and Brain Monitoring
会议开始日16.08.200http://aims.cuhk.edu.hk/converis/portal/Publication/4
会议完结日21.08.200http://aims.cuhk.edu.hk/converis/portal/Publication/4
会议地点Hong Kong
会议国家中国
期刊名称Acta Neurochirurgica -Supplementum then Supplement- Wien-
出版年份2005
月份1
日期1
卷号95
出版社SPRINGER-VERLAG WIEN
页次http://aims.cuhk.edu.hk/converis/portal/Publication/471 - http://aims.cuhk.edu.hk/converis/portal/Publication/47http://aims.cuhk.edu.hk/converis/portal/Publication/4
国际标準书号3-211-2http://aims.cuhk.edu.hk/converis/portal/Publication/4336-http://aims.cuhk.edu.hk/converis/portal/Publication/4
国际标準期刊号0065-1http://aims.cuhk.edu.hk/converis/portal/Publication/419
语言英式英语
关键词acute medicine; cerebrovascular accident; circulating nucleic acids; molecular diagnostics; nasopharyngeal cancer; plasma DNA; plasma RNA; stroke
Web of Science 学科类别Clinical Neurology; Neuroimaging; Neurosciences & Neurology; Surgery
