Publication in refereed journal
香港中文大学研究人员 ( 现职)
| 卢煜明教授 (化学病理学系) |
| 陈君赐教授 (化学病理学系) |
全文
| 数位物件识别号 (DOI) http://dx.doi.org/10.1016/S1044-579X(02)00091-3 |
引用次数
Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/48WOS source URL
其它资讯
摘要The demonstration of Epstein-Barr virus (EBV) DNA in the Plasma/serum of patients suffering from nasopharyngeal carcinoma (NPC) has provided us with a new tool for NPC detection and monitoring. The sensitivity and specificity Of using circulating EBV DNA for the detection of NPC, with real-time polymerase chain reaction analysis, is 96 and 93 %, respectively. EBV DNA level has been shown to be more powerful than existing staging system in predicting outcomes and it could also identify patients with emergent clinical relapse. It is, therefore, expected that this promising molecular tumor marker would soon be incorporated into routine clinical use.
着者Chan KCA, Lo YMD
期刊名称SEMINARS IN CANCER BIOLOGY
出版年份2002
月份12
日期1
卷号12
期次6
出版社ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD
页次http://aims.cuhk.edu.hk/converis/portal/Publication/489 - 496
国际标準期刊号1044-579X
语言英式英语
关键词cancer screening; circulating nucleic acids; nasopharyngeal carcinoma; plasma DNA
Web of Science 学科类别Oncology; ONCOLOGY
