Publication in refereed journal
香港中文大学研究人员 ( 现职)
| 卢煜明教授 (化学病理学系) |
| 刘子建教授 (妇产科学系) |
| 梁子昂教授 (妇产科学系) |
全文
| 数位物件识别号 (DOI) http://dx.doi.org/10.1016/S0140-6736(00)03237-2 |
引用次数
Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/45WOS source URL
其它资讯
摘要Fetal DNA is present in maternal plasma, and a proportion of such DNA is seen in intact fetal cells. We investigated the use of fluorescence in-situ hybridisation (FISH) techniques on maternal plasma samples, in plasma samples obtained from three women carrying fetuses affected by trisomy 21 (Down's syndrome), we identified fetal cells with three chromosome-21 signals. These results show the feasibility of non-invasive detection of fetal chromosomal aneuploidy by maternal plasma analysis.
着者Poon LLM, Leung TN, Lau TK, Lo YMD
期刊名称Lancet
出版年份2000
月份11
日期25
卷号356
期次9244
出版社LANCET LTD
页次1819 - 1820
国际标準期刊号0140-6736
电子国际标準期刊号1474-547X
语言英式英语
Web of Science 学科类别General & Internal Medicine; Medicine, General & Internal; MEDICINE, GENERAL & INTERNAL
