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Human chorionic gonadotropin: a secretory hormone (1999)_香港中文大学化學病理學系 (CPY)研究成果

香港中文大学 辅仁网/2017-06-20

Human chorionic gonadotropin: a secretory hormone
Publication in refereed journal


香港中文大学研究人员 ( 现职)
潘力行教授 (化学病理学系)


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Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/7WOS source URL

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摘要There are several physiological and pathophysiological situations where there is an apparent fluid flux across plasma membranes at the time when human chorionic gonadotropin (hCG) levels are high. These fluxes may take the form of a fluid loss from gastrointestinal tract (e.g. emesis/hyperemesis gravidarum) or accumulations in enclosures (e.g. amniotic fluid or hydatidiform mole). What is not obvious though is whether hCG is the cause of these fluid fluxes. Although glycoprotein hormones like hCG are mainly hormonogenic, their action in the latter process involves the efflux or conductance of halide ions. Since the basis of fluid secretion is an active afflux of ions such as chloride stimulated by a humoral agent, accompanied by a passive diffusion of water across a cell wall, I hypothesize that hCG is also a secretory hormone and responsible for fluid fluxes in the above and other clinical situations.

着者Panesar NS
期刊名称MEDICAL HYPOTHESES
出版年份1999
月份8
日期1
卷号53
期次2
出版社CHURCHILL LIVINGSTONE
页次136 - 140
国际标準期刊号0306-98http://aims.cuhk.edu.hk/converis/portal/Publication/7http://aims.cuhk.edu.hk/converis/portal/Publication/7
语言英式英语

Web of Science 学科类别Medicine, Research & Experimental; MEDICINE, RESEARCH & EXPERIMENTAL; Research & Experimental Medicine

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