姓 名：赵 冉 性 别：女

出生年月：1989.12籍 贯：河南渑池

政治面貌：中共党员毕业院校：郑州大学

学历：博士研究生研究方向：癌症的化学预防

工作单位：郑州大学 基础医学院 职称：讲师

病理生理学

电 话：**687邮 箱：zhaorpp1208@126.com

2016.9-2020.6: 博士研究生 郑州大学基础医学院 病理学与病理生理学 2012.9-2015.6: 硕士研究生 广西大学动物科技学院 动物遗传育种与繁殖 2008.9-2012.7: 本科河南科技大学动物科技学院 动物科学

1. 国家自然基金面上项目，NSFC**, Caspase-7通过新型靶基因抑制皮肤癌的调控机制研究. 2017.01-2020.12, 58万，在研，参加

2. 国家自然基金面上项目，NSFC**, TAOK1激酶作为食管鳞癌潜在治疗靶点的功能研究. 2020.01-2023.12, 51万，在研，参加

1.Zhao R^#,Choi BY^#, Wei L^#, Fredimoses M. ^#, Yin F, Fu X, Chen H, LiuK, Bode AM, Kundu JK, Dong Z, Lee MH. Acetylshikonin suppressed growth ofcolorectal tumour tissue and cells by inhibiting the intracellular kinase,T-lymphokine-activated killer cell-originated protein kinase. British Journalof Pharmacology. 2020; 177(10):2303-2319.

2.Zhao R, Choi BY, Lee MH, Bode AM, Dong Z. Implicationsof Genetic and Epigenetic Alterations of CDKN2A (p16(INK4a)) in Cancer.EBioMedicine. 2016; 8:30-39.

3.Zhao R^#,Huang H^#, Choi BY^#, Liu X,Zhang M,Zhou S,Song M,Yin F,Chen H,Shim JH,Bode AM,Dong Z,Lee MH.Cell growth inhibition by 3-deoxysappanchalcone is mediated by directlytargeting the TOPK signaling pathway in colon cancer. Phytomedicine.2018; 61:152813.

4.Song M^#, Yin S^#, Zhao R, Liu K, Kundu JK, Shim JH,Lee MH, Dong Z. (S)-10-Hydroxycamptothecin InhibitsEsophageal Squamous Cell Carcinoma Growth In Vitro and In Vivo Via DecreasingTopoisomerase I Enzyme Activity. Cancers. 2019; 11(12):1964.

5.Liu X^#, Song M^#, Liu K^#, Zhao R, Chen H, Zhang M, Shi Y, Liu K, Liu F, YangR, Li E, Bode AM, Dong Z,Lee MH. Targeted therapy of the AKT kinase inhibits esophageal squamous cell carcinomagrowth in vitro and in vivo. International Journal of Cancer, 2018; 145(4):1007-1019.

6.Song M^#, Liu X^#, Liu K^#, Zhao R, Huang H, Shi Y, Zhang M, Zhou S, Xie H, ChenH, Li Y, Zheng Y, Wu Q, Liu F, Li E, Bode AM, Dong Z,Lee MH. TargetingAKT with Oridonin Inhibits Growth of Esophageal Squamous Cell Carcinoma InVitro and Patient-Derived Xenografts In Vivo. Mol Cancer Ther. 2018; 17(7):1540-1553.

7.Yin S^#, Song M^#,Zhao R, Liu X, Kang WK, Lee JM, Kim YE, ZhangC, Shim JH, Liu K, Dong Z,Lee MH. Xanthohumol Inhibits the Growth ofKeratin 18-Overexpressed Esophageal Squamous Cell Carcinoma in vitro and invivo. Front Cell Dev Biol. 2020; 8:366.