基本信息科学研究 RESEARCHES个人新闻 / News论文著作 PUBLICATIONS
个人信息 PERSONAL INFORMATION

基本信息/ Personal Information

王磊，哈尔滨工业大学化工与化学学院高分子科学与工程系教师，硕士生导师；中国复合材料学会会员。

主持及参与完成国家自然科学基金等基金项目10项。迄今在 Angew. Chem. Int. Ed., Sci. Robotics, Adv. Sci., Adv. Funct. Mater., Small, Lab Chip, Anal. Chem. 等国际高水平杂志上发表了50余篇SCI论文，其中通讯作者（含第一作者）论文20余篇。影响因子大于10的8篇，大于5的30篇；论文总引次数超过850次。此外，申请国家发明专利14项，其中三项已经获得授权。

Lei Wang, Assistant Professor, School of Chemistry & Chemical Engineering, Harbin Institute of Technology, China. He participated in 10 funding programs, including 2 from National Natural Science Foundation of China.So far, he has published more than 50 peer-reviewed papers in high-level international journals, including Angew. Chem. Int. Ed., Sci. Robotics, Adv. Funct. Mater., Small, Lab Chip, ACS Nano, Anal. Chem.,which have been cited more than 850 times. He also applied 14 national invention patents, three of which have been authorized.

工作经历 / Working Experience

2017.12-至今玛丽居里学者，西班牙生物工程研究所

2016.03-至今讲师，哈尔滨工业大学化工与化学学院

课题组负责人：黄鑫教授 http://homepage.hit.edu.cn/huangxin

2015.08-2016.02 助教/博士后，哈尔滨工业大学化工与化学学院

2017.12-Now Marie Curie Research fellow, Institute of Bioengineering, Spain.

2016.03-Now Assistant Professor, School of Chemistry & Chemical Engineering, HIT

2015.08-2016.02 Postdoc Research fellow, School of Chemistry & Chemical Engineering, HIT

Supervisor: Prof. Xin Huang, http://homepage.hit.edu.cn/huangxin

教育经历 / Education Background

2004.09-2008.06QUST, Bachelor, Supervisor: Prof. Guangming Nie

2008.09-2011.06QUST, Master, Supervisor: Prof. Shusheng Zhang& Prof. Guifen Jie

Research area: Electrochemiluminescence;

2011.09-2015.07 HIT, Ph.D, Supervisor: Prof. X. Han

Research area: Self-assembly of biomaterials & Microfluidics

2012.12-2013.12University of Maryland, USA, Joint Ph. D student, Supervisor: Prof. Zhihong Nie,

http://www2.chem.umd.edu/groups/znie/

2014.07-2014.12University of Leeds, UK, Joint Ph. D student, Supervisor: Prof. S. D. Evans

http://www.mnp.leeds.ac.uk/steve-evans.html


研究领域 / Research Areas
研究方向：生物纳米材料自组装在药物靶向释放、微纳米马达和功能化原细胞模拟中的应用。

Research areas: Controlled drug release, fabrication of micromotors, and preparation of functional protocells based on the self-assembly of biomaterials.

科研项目

项目名称新型仿生膜体系的制备和应用研究

项目来源国家自然科学基金面上项目

项目经费80万元

担任角色参与

项目类别纵向项目

项目状态完成



荣誉称号 / Honors & Fellowships

奖项名称欧盟玛丽居里项目资助

获奖时间2017年



奖项名称博士生国家奖学金

获奖时间2013年11月



奖项名称国家留学基金委短期访学基金

获奖时间2013年8月



奖项名称Short-term visiting programme from CSC

获奖时间Aug. 2013



奖项名称National scholarship for Ph.D student

获奖时间Nov. 2013



国内外合作 / Collaboration
德国马克普朗克研究所/西班牙生物工程研究所

Institute of Bioengineering Catalonia, Spain/

Max Planck Institute of Intelligent system, Germany

Prof. S. Sanchez, http://www.is.mpg.de/sanchez
http://www.ibecbarcelona.eu/nanodevices

美国马里兰大学 University of Maryland, USA
Prof. Zhihong Nie, http://www2.chem.umd.edu/groups/znie/

Currently moved to Fudan University: https://www.nielab.com/research

美国康尼迪格大学University of Connecticut, USA

Prof. Jie He, http://jiehe.lab.uconn.edu/

南京师范大学 Nanjing Normal University

Prof. Ben Liu, http://hky.njnu.edu.cn/info/1072/3808.htm

英国利兹大学 University of Leeds, UK

Prof. S. Evans, http://www.mnp.leeds.ac.uk/steve-evans.html


讲授课程 / Courses
Biomedical polymers for undergraduates in each semester.

个人新闻 / News

新闻标题Congratulations to Dr. Lei Wang for obtaining the Best Poster Award at 2016 SIPCD!

发表时间Sep. 2016

Congratulations to Dr. Lei Wang for obtaining the Best Poster Award at 2016 SIPCD!

The details can be seen from the following link:

https://twitter.com/Biomac_ACS


新闻标题Jiaqiang, Weiran, Zibo and Yuxiong joined our group for conducting the innovation experiments!!! Welcome~

发表时间Dec.01, 2016

Jiaqiang, Weiran, Zibo and Yuxiong joined our group for conducting the innovation experiments!!! Welcome~

Their research topic would be the fabrication of microfibers using microfluidics.


新闻标题Congratulations to Dr. Wang for the Chem. Commun paper！

发表时间2017-07-07

Our paper on ''Single-step fabrication of multi-compartmentalized biphasic proteinosomes'' is accepted for publication in Chem. Commun. !!! Congratulations to Lei and all the coauthors!!!

http://pubs.rsc.org/en/content/articlelanding/2017/cc/c7cc04180b#!divAbstract


新闻标题Dr. Wang attended the 2017 International Conference on Micro/Nano Machines, at Wuhan.

发表时间2017-08-25


新闻标题Dr. Wang obtained the Marie Curie fellowship from EU.

发表时间2017-11-01

Dr. Wang successfully arrived at the Bio-nanodevices Group, led by Prof. S. Sanchez, with the Marie Curie fellowship supporting on the project of Protein-based micromotors.



新闻标题Congratulations to Dr. Wang for the Anal. Chem. paper！

发表时间2018-08-21

Our paper was accepted for publication in Anal. Chem. Congratulations to Lei and all the coauthors!!!

Signal-On Electrochemiluminescence of Self-Ordered Molybdenum Oxynitride Nanotube Arrays for Label-Free Cytosensing

L. Wang, D.Q. Liu, Y. Sun, J.J. Su, B.W. Jin, L. Geng, Y.-Y. Song*, X. Huang*, and M. Yang*

Anal. Chem., 2018, DOI: 10.1021/acs.analchem.8b02196. (IF=6.042)



新闻标题Congrats to Dr. Wang for the paper published on Angew. Chem.!

发表时间2018-11-27

Many thanks to Prof. Huang for the guidance and help in the paper supervision!!! Also appreciate all the contributions from coauthors! Thanks.

Autonomic Behaviors in Lipase-active Oil Droplets

Lei Wang, Youping Lin (Equal contribution), Yuting Zhou, Hui Xie, Jianmin Song, Mei Li, Yudong Huang, Xin Huang*, and Stephen Mann*. Angew. Chem. 2018, DOI:10.1002/anie.**

https://onlinelibrary.wiley.com/doi/10.1002/anie.**



新闻标题Congrats to Dr. Wang for the Angew. Chem. paper!

发表时间Apr. 16, 2019

Lipase‐powered mesoporous silica nanomotors for triglyceride degradationhttps://onlinelibrary.wiley.com/doi/abs/10.1002/anie.**


代表论文 / Representative Publications

2019年

[50] Lipase-powered Mesoporous Silica Nanomotors for Triglyceride Degrdation.

L. Wang, A.C. Hortelao, X. Huang, and S. Sanchez*
Angew. Chem. Int. Ed., 2019,

https://onlinelibrary.wiley.com/doi/abs/10.1002/anie.**
[49] Autonomic Behaviors in Lipase-Active Oil Droplets,

L. Wang, Y.P. Lin, Y.T. Zhou, H. Xie, J. Song, M. Li, Y.D. Huang, X. Huang*, and S. Mann*.

Angew. Chem. Int. Ed., 2019, 58，1067.
[48] Enzyme-Modulated Anaerobic Encapsulation of Chlorella Cells Allows Switching from O2 to H2 Production,

D. Su, J. Qi, X. Liu, L.Wang, H. Zhang, H. Xie, and X. Huang*

Angew. Chem. Int. Ed., 2019, 58, 3992–3995. (VIP)
[47] Reconfigurable magnetic microrobot swarm:Multimode transformation, locomotion,and manipulation,

H. Xie,* M. Sun , X. Fan, Z. Lin, W. Chen, L. Wang,L Dong*, Q. He*

Sci. Robot. 2019, 4, eaav8006.

2018年

[46] Signal-On Electrochemiluminescence of Self-Ordered Molybdenum Oxynitride Nanotube Arrays for Label-Free Cytosensing

L. Wang, D.Q. Liu, Y. Sun, J.J. Su, B.W. Jin, L. Geng, Y.-Y. Song*, X. Huang*, and M. Yang*

Anal. Chem., 2018, 90 (18), 10858–10864. (IF=6.042, Highlighted in the Journal homepage)



[45] Design and Construction of Hybrid Microcapsules with Higher-Order Structure and Multiple Functions

G.Y. Wu, L.Wang,* P.Zhou, P. Wen, C. Ma, X. Huang,* and Y.D. Huang*

Adv. Sci., 2018, 5, **. (IF=12.441)



2017年

[44] One-step self-assembly of hybrid janus-like capsule for NIR-controlled release

L. Wang, G.Y. Wu, X.M. Liu, and X. Huang*

J. Controlled Release., 2017, 259, doi:10.1016/j.jconrel.2017.03.169. (IF=7.877)

[43] Single-step fabrication of multi-compartmentalized biphasic proteinosomes.

L. Wang, P. Wen, X.M. Liu, Y.T. Zhou, M. Li, Y.D. Huang, L. Geng, S. Mann,* and X. Huang*

Chem. Comm. 2017, 53, 8537-8540. http://dx.doi.org/10.1039/C7CC04180B (IF=6.319)


[42] In Situ Generation of Core-Shell Protein-Based Microcapsules with Regulated Ion Absorbance Capacity

P. Zhou, L. Wang,* G. Wu, Y. Zhou, M. Hegazy, and X. Huang*

Chemistry Select, 2017, 2, 6249-6253. http://onlinelibrary.wiley.com/doi/10.1002/slct.**/full



[41] Efficient Way to Generate Protein-based Nanoparticles by in-Situ Photoinitiated Polymerization-Induced Self-Assembly.

C. Ma, X.M. Liu,* G.Y. Wu, P. Zhou, Y.T. Zhou, L. Wang, and X. Huang,*

ACS Macro Lett., 2017, 6, 689-694.



[40] In Situ Gelation-Induced Death of Cancer Cells Based on Proteinosomes

Y. T. Zhou, J. M. Song, L.Wang*, X.T. Xue, X.M. Liu, H. Xie* and X. Huang*

Biomacromolecules, 2017, 18 (8), 2446-2453.



[39] Coordinated Membrane Fusion of Proteinosomes by Contact Induced Hydrogel Self-healing

P. Wen, X.M. Liu, L. Wang, M. Li, Y.D. Huang, X. Huang* and S. Mann*.

Small, 2017, **.


[38] Engineering DNA-based capsule used as a platform for carrying various molecules

G. Wu, L. Wang, X. Huang*, and Y.D. Huang.

J. Control. Release, 2017,259,36.

2016年

[37] Bio-inspired Engineering Proteinosomes with Cell Wall like Protective Shell by Self-assembly of Metal-chelated Complex

D. Su, X.M. Liu,* L. Wang, C. Ma, H. Xie, H. Zhang, X. Meng, Y.D. Huang, and X. Huang*

Chem. Comm., 2016, 52, 13803-13806.



[36] Programmable modulation of membrane permeability of proteinosome upon multiple stimuli responses

P. Zhou, X.M. Liu*, G.Y. Wu, P. Wen, L. Wang, Y.D. Huang, and X. Huang*

ACS Macro Lett. 2016, 5, 961-966.



[35] Formation of hybrid core-shell microgels induced by autonomousunidirectional migration of nanoparticles

J.Y. Wang, K. Song, L.Wang, Y.J. Liu, B. Liu, J. Zhu, X. Xie, and Z.H. Nie*

Mater. Horiz., 2016, 3, 78-82. (IF=13.183)



[34] Light-triggeredgeneration of multifunctional gas-filled capsules on-demand

L. Wang, J.Y. Wang, K. Song, W. Li, Z.Q.Huang, J. Zhu, X. Han*, and Z.H. Nie*

J. Mater. Chem. C, 2016, 4, 652-658. (Journal of Materials Chemistry C, Hot Paper)



[33] CdS-modified Porous Foam Nickel for Label-freeHigh Efficient Detection of Cancer Cells

B. Dai, L.Wang *, J. Shao, X.Huang*,and G. Yu*

RSC Adv., 2016, 6, 32874–32880.

[32] Electrochemiluminescence Biosensor Based on CdS-modified Silica NPs for Cancer Cell Detection

B. Dai, J. Shao, Y. Song, G. Yu, Y. Guan, L. Wang, D. Gao.

Basic Clin. Pharmacol. Toxicol., 2016, 118,51.

[31] Polyacrylate emulsion containing IBOMA for removable pressure sensitive adhesives

L. Zhang, Y. Cao, L. Wang, L. Shao, Y. Bai*

J. Appl. Polym. Sci., 2016, 133, 42886.


2015年

[30] Continuousmicrofluidic self-assembly of hybrid Janus-like vesicular motors: autonomousmovement and controlled release

L.Wang, Y.J. Liu (Equal contribution), J. He, M. J.Hourwitz, Y.L. Yang, J. Fourkas, X.Han* and Z.H. Nie*

Small, 2015, 11, 3762–3767. (featured by website of Harbin Institute of Technology)



[29] Photosynthetic Proteinin Supported Lipid Bilayers - Towards a Biokleptic Approach for Energy Capture

L. Wang, J. S. Roth, X.Han, and S. D.Evans*

Small, 2015, 11, 3306-3318.



[28] A NovelElectrochemiluminescence Immunosensor Based on CdS-Coated ZnO Nanorods arrayfor HepG2 Cell Detection

D. Liu, L.Wang (Equal contribution), S. Ma, Z. Jiang, B. Yang,X.Han*, and S.Q. Liu*

Nanoscale, 2015, 7, 3627-3633.



[27] Self-assembly viamicrofluidics

L. Wang and S. Sanchez*

Lab Chip, 2015, 15,4383-4386.

[26] Morphology-controlledSynthesis of Ag nanoparticles-decorated poly(o-phenylenediamine) usingmicrofluidics and its application for hydrogen peroxide detection

L. Wang, S. Ma, B. Yang, W. Cao, and X.Han*

Chem. Eng.J. 2015, 268, 102-108. (JOURNAL FRONT COVER PAPER)



[25] A novel porousadhesion material with ink absorbency for digital inkjet printing

L. Zhang, Y. Cao, L.Wang*, L. Shao and Y. Bai*

RSC Adv., 2015, 5, 36288–36294.



[24] Preparation andproperties of aligned graphene composites

D. Li, Y. Liu, H.Ma, Y. Wang, L. Wang and Z. Xie

RSC Adv., 2015, 5, 31670-31676.


[23] Preparation andproperties of polyurethane modified epoxy cured in the different simulatedgravity environments

D. Li, Y. Liu, H.Kang, H. Tan, L. Wang, and C. Zhang

J. Appl. Polym. Sci. 2015, 132, 42063.

[22] A Highly Efficient ZrO₂ Nanoparticle Based Electrochemical Sensor for the Detection of OrganophosphorusPesticides

H. Wang, Y. Su,H. Kim, D. Yong, L. Wang, and X.Han*

Chin. J. Chem., 2015, 33, 1135–1139.
[21] Micromixingenhancement in a novel passive mixer with symmetrical cylindrical grooves

L. Wang, S. Ma and X.Han*

Asia-Pac. J. Chem. Eng. 2015, 10, 201-209.



Before 2014

[20] Lipid nanotubeformation using space regulated electric field above interdigitated electrodes

H. Bi, Di. Fu, L.Wang and X.Han*

ACS Nano, 2014, 8 (4), 3961-3969. (IF=13.709, featured by website of HarbinInstitute of Technology)


[19] A novel quantum dotnanocluster as versatile probe for electrochemiluminescence andelectrochemicalassays of DNA and cancer cells

G.F. Jie, J. Zhang, G.Jie, and L. Wang

Biosensors andBioelectronics, 2014, 52, 69-75.



[18] Interactions of thebaicalin and baicalein with bilayer lipid membranes investigated by cyclicvoltammetry and UV-Vis spectroscopy

Y. Zhang, X.J. Wang, L.Wang, M. Yu and X.Han*

Bioelectrochemistry, 2014, 95, 29-33.


[17] Synthesis andproperties of soap-free P(2-EHA-BA) emulsion for removable pressure sensitiveadhesives

L. Zhang, Y. Cao, L. Wang, L. Shao, and Y. Bai*

RSC Adv., 2014, 4, 47708-47713.


[16] The influences ofdifferent gravity environments on the curing process and cured products ofcarbon- nanotube-reinforced epoxy composites

D. Li, Y. Liu,Y. Wang, H. Kang, L. Wang, and H. Tan

J. Appl. Polym. Sci. 2014, 132, 41413.

[15] Mixing enhancement ofnovel passive microfluidic mixers with triangle-baffles

L. Wang, S. Ma, X. Wang, H. Bi, and X.Han*

Asia-Pac. J. Chem. Eng. 2014, 9(6), 877-885.



[14] Hydrodynamic-drivenself-assembly of giant vesicles of metal nanoparticles for remote-controlledrelease

J. He, Z. Wei, L.Wang, Z. Tomova, T. Babu, C. Wang, X.Han, J.Fourkas, and Z.H. Nie*

Angew. Chem. Int. Ed., 2013, 52, 2463-2468.


[13] Electroformation ofGiant Unilamellar Vesicles Using Interdigitated ITO Electrodes

H. Bi, B. Yang, L.Wang, W. Cao and X.Han*

J. Mater. Chem. A, 2013, 1, 7125-7130.


[12] Vesicularself-assembly of colloidal amphiphiles in microfluidics

J. He, L. Wang (Equal contribution), Z. Wei, Y. Yang, C. Wang,X. Han, and Z.H. Nie*

ACS Appl. Mater. Interfaces, 2013, 5, 9746-9751.



[11] Forming Lipid BilayerMembrane Arrays on Micropatterned Polyelectrolyte Film Surfaces

Y. Zhang, L.Wang, X. Wang, G. Qi, and X.Han

Chem. Eur. J., 2013, 19, 9059- 9063.

[10]ElectrochemiluminescentTiO₂/CdS nanocomposites for efficient immunosensing of HepG2 cells

L. Wang, S. Ma, X.J. Wang, D. Liu, S. Liu,and X.Han

J. Mater. Chem. B, 2013, 1, 5021-5027. (IF=4.872)


[9] Lipid Bilayer MembraneArrays: Fabrication and Applications

X.Han, G. Qi,X. Xu, and L. Wang

Adv. Biochem. Eng. Biot., 2013, 131, 121-152.


[8] Migration of ChargedSpecies in Lipid Bilayer Membranes under an Electric Field

X. Wang, L.Wang, X.Han and C. Guo*

Nano, 2013, 8 (1), ** (12 pages)


[7] Fabrication of ChemicalGradient Using Space Limited Plasma Oxidation and its Application on DropletMotion

X.Han*, L. Wang, and X.Wang

Adv. Funct. Mater., 2012, 22, 4533-4538. (featured by websites of MaterialsViewChina and Harbin Institute of Technology)


[6] Mixing enhancement ofnovel passive mixers with cylindrical grooves

L. Wang, Da. Liu, X. Wang, and X.Han*

Chem. Eng. Sci., 2012, 81, 157-163.

[5] Formation of Lipid Bilayer Microarrays on Photo-Oxidized Polystyrene Surfaces

X.Han, G. Qi,X. Xu, and L. Wang

Chem. Eur. J., 2011, 17, 14741-14744.


2009-2011 Publications from QUST:

[4] Versatile Electrochemiluminescence Assays for Cancer Cells Based on Dendrimer/CdSe-ZnS-Quantum Dot Nanoclusters

G.F. Jie, L.Wang, J. Yuan, and S.S. Zhang*

Anal. Chem., 2011, 83, 3873-3880. (IF=6.042, citation times=170 from GoogleScholar)


[3] Magnetic Electrochemiluminescent Fe₃O₄/CdSe@CdS Nanoparticle/Polyelectrolyte Nanocomposite for Highly Efficient Immunosensing of a CancerBiomarker

G.F. Jie, L. Wang, and S.S. Zhang*
Chem. Eur. J., 2011, 17, 641-648. (IF=5.771, citation times=68 from GoogleScholar)


[2]Electrochemiluminescence Imunosensor Based on Nanocomposite film of CdS QuantumDots-carbon Nanotubes Combined with Gold Nanoparticles-chitosan

G.F. Jie, P. Liu, L.Wang, and S.S. Zhang*

Electrochem. Commun., 2010, 12, 22-26. (IF=4.847, citation times=54 from GoogleScholar)


[1] Label-free Electrochemiluminescence Imunosensor Based on Nanocomposite film of CdS Quantum Dots/carbon Nanotubes

G.F. Jie, P. Liu, L.Wang, and S.S. Zhang*

Chin. J.Anal. Chem.,2009, 10 (37), F106.





专利 / Patents

出版物

出版物名称Nanomaterials for Tumor Targeting Theranostics: A Proactive Clinical Perspective

作者Lei Wang, et al.

出版时间,完成时间2016/2/22

出版社World Scientific

简单介绍Chapter 10 Microbubbles for Tumor Targeting Theranostics