出生年月：1988年12月
民族：汉族
职称：讲师
学科专业：分子生物学与生物化学
研究方向：真菌天然产物生物合成
电子邮箱：lqp_2019@scuec.edu.cn
办公室：药学院13-108
教育及工作经历
2019.8-至今 中南民族大学药学院，讲师
2018.7-2019.8 美国亚利桑那大学，博士后，合作导师：Prof. Istvan Molnar
2015.10-2017.10 美国亚利桑那大学，联合培养博士，导师：Prof. Istvan Molnar
2010.9-2018.6 华中农业大学食品科技学院，工学博士，导师：陈福生教授、王小红教授
2006.9-2010.6 华中农业大学食品科技学院，工学学士
研究领域
1、真菌天然产物的生物合成途径和机制研究
2、真菌聚酮合酶作用机制研究
科研项目
［1］翘孢霉属真菌XL029中新骨架聚酮杂萜化合物emerones A-C的生物合成研究（**），国家自然科学基金青年项目，24万，2021.01-2023.12，主持，在研。
［2］苯二酚内酯类与嗜氮酮类非还原型聚酮合酶组合生物合成产生新型活性分子的研究（2020CFB157），湖北省自然科学基金青年项目，5万，2020-03至2022-03，主持，在研。
［3］红曲菌中嗜氮酮型和萘酮型黄色素生物合成的研究（**），国家自然科学基金面上项目，59万，2019.01-2022.12，参与，在研。
［4］组蛋白去乙酰化酶介导的红曲菌次级代谢转录调控机制研究（**），国家自然科学基金面上项目，62万，2017.01-2020.12，参与，在研。
代表性研究成果
[1] Wenting Zhao^#, Qingpei Liu^#, Hengye Chen, Wei Zhao*, Yuan Gao*, Xiaolong Yang*. Two novel eremophylane acetophenone conjugates from Colletotrichum gloeosporioides, an endophytic fungus in Salvia miltiorrhiza. Fitoterapia, 2020, 141: 104474.
[2] Wanping Chen^#, Runfa Chen^#, Qingpei Liu^#, Yi He, Kun He, Xiaoli Ding, Lijing Kang, Xiaoxiao Guo, Nana Xie, Youxiang Zhou*, Yuanyuan Lu, Russell J. Cox, Istvan Molnar*, Mu Li, Yanchun Shao, Fusheng Chen*. Orange, red, yellow: biosynthesis of azaphilone pigments in Monascusfungi. Chemical Science, 2017, 8 (7), 4917-4925. (Nature指数收录)
[3] Qingpei Liu, Li Cai, Yanchun Shao, Youxiang Zhou, Mu Li, Xiaohong Wang*, Fusheng Chen*. Inactivation of the global regulator LaeA in Monascus ruberresults in a species-dependent response in sporulation and secondary metabolism. Fungal Biology, 2016, 120 (3): 297-305.
[4] Qingpei Liu, Nana Xie, Yi He, Li Wang, Yanchun Shao, Hongzhou Zhao, Fusheng Chen*. MpigE, a gene involved in pigment biosynthesis in Monascus ruberM7. Applied Microbiology and Biotechnology,2014, 98 (1): 285-296.
[5] Haili Chen^#, Wenting Zhao^#, Qingpei Liu, Hengye Chen, Wei Zhao*, Dengfeng Yang*, Xiaolong Yang*.(±)-Preisomide: A new alkaloid featuring a rare naturally occurringtetrahydro-2H-1,2-oxazin skeleton from an endophytic fungus Preussiaisomeraby using OSMAC strategy. Fitoterapia, 2020, 141: 104475.
[6] Chen Wang, Xiaojing Wang, Liwen Zhang, Qun Yue, Qingpei Liu, Ya-ming Xu, A. A. Leslie Gunatilaka, Xiaoyi Wei, Yuquan Xu*, Istvan Molnar*. Intrinsic and extrinsic programming of product chain length and release mode in fungal collaborating iterative polyketide synthases. Journal of the American Chemical Society, 2020. (Nature指数收录)
[7] Mu Li, Lijing Kang, Xiaoli Ding, Jiao Liu, Qingpei Liu, Yanchun Shao, Istvan Molnar*, Fusheng Chen*. Monasone naphthoquinone biosynthesis and resistance in Monascusfungi. mBio, 2020, 11(1):e02676-19.
[8] Xiaojing Wang^#, Chen Wang^#, Lixin Duan^#, Liwen Zhang, Hang Liu, Ya-ming Xu, Qingpei Liu, Tonglin Mao, Wei Zhang, Ming Chen, Min Lin, A. A. Leslie Gunatilaka, Yuquan Xu*, Istvan Molnar*. Rational reprogramming of O-methylation regioselectivity for combinatorial biosynthetic tailoring of benzenediol lactone scaffolds. Journal of the American Chemical Society, 2019, 141 (10), 4355-4364. (Nature指数收录)
[9] Jiao Liu^#, Youxiang Zhou^#, Tao Yi, Mingming Zhao, Nana Xie, Ming Lei, Qingpei Liu, Yanchun Shao, Fusheng Chen*. Identification and role analysis of an intermediate produced by a polygenic mutant of Monascuspigments cluster in Monascus ruberM7. Applied Microbiology and Biotechnology, 2016, 100 (16): 7037-7049.
[10] Nana Xie, Qingpei Liu, Fusheng Chen*. Deletion of pigRgene in Monascus ruberleads to loss of pigment production. Biotechnology Letters, 2013, 35 (9): 1425-1432.
[11] Yi He, Qingpei Liu, Yanchun Shao*, Fusheng Chen*. ku70and ku80null mutants improve the gene targeting frequency in Monascus ruberM7. Applied Microbiology and Biotechnology, 2013, 97 (11): 4965-4976.